In this study,a novel strategy for developingα+βdual-phase titanium alloys with low Young's modulus and high yield strength was proposed,and a Ti-15Nb-5Zr-4Sn-1 Fe alloy was developed through theoretical composi...In this study,a novel strategy for developingα+βdual-phase titanium alloys with low Young's modulus and high yield strength was proposed,and a Ti-15Nb-5Zr-4Sn-1 Fe alloy was developed through theoretical composition design and microstructure manipulation.After hot-rolling and subsequent annealing,a high volume fraction of ultrafine grainedαphase embedded in metastableβ-matrix was formed in the microstructure as intended.Consequently,this alloy exhibits both low Young's modulus(61 GPa)and high yield strength(912 MPa).The experimental results prove that the proposed strategy is appropriate for developing titanium alloys with superior yield strength-to-modulus ratio than those of conventional metallic biomedical materials.Present study might shed light on the research and development of advanced biomedical titanium alloys with low Young's modulus and high yield strength.展开更多
为了获得抗病毒能力较强的海南番木瓜转基因新品系,采用海南番木瓜环斑花叶病毒外壳蛋白(PapayaRing Spot Virus-Capsid Protein of Hainan,HPRSV-CP)和重组人源干扰素α-2b(recombinant human interferon-α 2b,rhIFNα-2b)为目的基因...为了获得抗病毒能力较强的海南番木瓜转基因新品系,采用海南番木瓜环斑花叶病毒外壳蛋白(PapayaRing Spot Virus-Capsid Protein of Hainan,HPRSV-CP)和重组人源干扰素α-2b(recombinant human interferon-α 2b,rhIFNα-2b)为目的基因,利用pBI121、pCAMBIA2300载体及相关技术(如技术基因内部位点突变套叠PCR),实施双价基因表达载体的构建策略。本研究成果可为其他多价基因表达载体的构建提供技术依据。展开更多
基金the National Natural Science Foundation of China(Nos.51671012,51831006 and 51971009)the International Science and Technology Cooperation Program of China(No.2015DFA51430)the Fundamental Research Funds for the Central Universities。
文摘In this study,a novel strategy for developingα+βdual-phase titanium alloys with low Young's modulus and high yield strength was proposed,and a Ti-15Nb-5Zr-4Sn-1 Fe alloy was developed through theoretical composition design and microstructure manipulation.After hot-rolling and subsequent annealing,a high volume fraction of ultrafine grainedαphase embedded in metastableβ-matrix was formed in the microstructure as intended.Consequently,this alloy exhibits both low Young's modulus(61 GPa)and high yield strength(912 MPa).The experimental results prove that the proposed strategy is appropriate for developing titanium alloys with superior yield strength-to-modulus ratio than those of conventional metallic biomedical materials.Present study might shed light on the research and development of advanced biomedical titanium alloys with low Young's modulus and high yield strength.
文摘为了获得抗病毒能力较强的海南番木瓜转基因新品系,采用海南番木瓜环斑花叶病毒外壳蛋白(PapayaRing Spot Virus-Capsid Protein of Hainan,HPRSV-CP)和重组人源干扰素α-2b(recombinant human interferon-α 2b,rhIFNα-2b)为目的基因,利用pBI121、pCAMBIA2300载体及相关技术(如技术基因内部位点突变套叠PCR),实施双价基因表达载体的构建策略。本研究成果可为其他多价基因表达载体的构建提供技术依据。
