目的测定5个不同厂家(分别以代码A,B,C,D和E表示)三黄片的体外溶出度,为评价和控制药品质量提供依据和参考。方法以水为释放介质,用高效液相色谱法对不同厂家的三黄片的溶出度进行测定和比较。使用SPSS中的一般线性模型(general linear ...目的测定5个不同厂家(分别以代码A,B,C,D和E表示)三黄片的体外溶出度,为评价和控制药品质量提供依据和参考。方法以水为释放介质,用高效液相色谱法对不同厂家的三黄片的溶出度进行测定和比较。使用SPSS中的一般线性模型(general linear model)对不同厂家三黄片的体外溶出度进行多重比较。结果5个不同厂家相互之间的溶出度有显著差异(Sig.<0.01),只有厂家A和厂家B之间无显著差异(Sig.=0.945),厂家C和厂家E之间无显著差异(Sig.=0.238)。结论有必要对各个厂家的三黄片剂进行溶出度检查,以保证临床用药疗效。展开更多
Tuber borchii is an ectomycorrhizal edible truffle, commonly called “bianchetto” (whitish truffle) to distinguish it from the more valuable white truffle found in Italy (T. magnatum). Although Tuber borchii also has...Tuber borchii is an ectomycorrhizal edible truffle, commonly called “bianchetto” (whitish truffle) to distinguish it from the more valuable white truffle found in Italy (T. magnatum). Although Tuber borchii also has a fairly high commercial value, information on its ecology, and especially its optimum rainfall and temperature values are lacking. In recent years the issue of climate change has steadily grown in importance, not only in the scientific world, but also politically and in civil society. Over the last century there has been a general increase in the temperature in Italy of about 1°C. Several studies have underlined how climatic changes influence the optimum growth and distribution of various species of truffle. This contribution aims to illustrate the fluctuation of T. borchii sporocarps production in different timescales and show how these alterations are driven by rainfall and temperature factors. The research, carried out in five different natural T. borchii production areas, reveals that the production of truffles is significantly higher after autumn months characterized by abundant rainfall and cold temperatures.展开更多
General linear model (GLM) is the most popular method for functional magnetic resource imaging (fMRI) data analysis . However, its theory is imperfect. The key of this model is how to constitute the design-matrix to m...General linear model (GLM) is the most popular method for functional magnetic resource imaging (fMRI) data analysis . However, its theory is imperfect. The key of this model is how to constitute the design-matrix to model the interesting effects better and separate noises better. For the purpose of detecting brain function activation , according to the principle of GLM,a new convolution model is presented by a new dynamic function convolving with design-matrix,which combining with t-test can be used to detect brain active signal. The fMRI imaging result of visual stimulus experiment indicates that brain activities mainly concentrate among v1and v2 areas of visual cortex, and also verified the validity of this technique.展开更多
文摘目的测定5个不同厂家(分别以代码A,B,C,D和E表示)三黄片的体外溶出度,为评价和控制药品质量提供依据和参考。方法以水为释放介质,用高效液相色谱法对不同厂家的三黄片的溶出度进行测定和比较。使用SPSS中的一般线性模型(general linear model)对不同厂家三黄片的体外溶出度进行多重比较。结果5个不同厂家相互之间的溶出度有显著差异(Sig.<0.01),只有厂家A和厂家B之间无显著差异(Sig.=0.945),厂家C和厂家E之间无显著差异(Sig.=0.238)。结论有必要对各个厂家的三黄片剂进行溶出度检查,以保证临床用药疗效。
文摘Tuber borchii is an ectomycorrhizal edible truffle, commonly called “bianchetto” (whitish truffle) to distinguish it from the more valuable white truffle found in Italy (T. magnatum). Although Tuber borchii also has a fairly high commercial value, information on its ecology, and especially its optimum rainfall and temperature values are lacking. In recent years the issue of climate change has steadily grown in importance, not only in the scientific world, but also politically and in civil society. Over the last century there has been a general increase in the temperature in Italy of about 1°C. Several studies have underlined how climatic changes influence the optimum growth and distribution of various species of truffle. This contribution aims to illustrate the fluctuation of T. borchii sporocarps production in different timescales and show how these alterations are driven by rainfall and temperature factors. The research, carried out in five different natural T. borchii production areas, reveals that the production of truffles is significantly higher after autumn months characterized by abundant rainfall and cold temperatures.
基金Supported by National Natural Science Foundation of China (No.90208003, 30200059), the 973 Project (No. 2003CB716106), Doctor training Fund of MOE, P.R.C., and Fok Ying Tong Education Foundation (No.91041)
文摘General linear model (GLM) is the most popular method for functional magnetic resource imaging (fMRI) data analysis . However, its theory is imperfect. The key of this model is how to constitute the design-matrix to model the interesting effects better and separate noises better. For the purpose of detecting brain function activation , according to the principle of GLM,a new convolution model is presented by a new dynamic function convolving with design-matrix,which combining with t-test can be used to detect brain active signal. The fMRI imaging result of visual stimulus experiment indicates that brain activities mainly concentrate among v1and v2 areas of visual cortex, and also verified the validity of this technique.
