Water-soluble porphyrin, as a kind of photosensitive agent and good anticancer modelcompound. may find wide application in the diagnosis and photo-dynamic therapy of can-cer. For its clinical uses. it is very importan...Water-soluble porphyrin, as a kind of photosensitive agent and good anticancer modelcompound. may find wide application in the diagnosis and photo-dynamic therapy of can-cer. For its clinical uses. it is very important to elucidate the interaction mechanism ofporphyrin with DNA at molecular level. In 1990. when Turpin et al.studied展开更多
A novel water-soluble porphyrin[5,10,15,20-tetra（3-ethoxy-4-hydroxy-5-sulfonate）phenyl porphyrin, H2TEHPPS] was designed and synthesized, which could be used as a potential fluorescence sensor to detect temperature ...A novel water-soluble porphyrin[5,10,15,20-tetra（3-ethoxy-4-hydroxy-5-sulfonate）phenyl porphyrin, H2TEHPPS] was designed and synthesized, which could be used as a potential fluorescence sensor to detect temperature changes. The studies were performed in solution phase and the concentration of H2TEHPPS was 2.0×10^-5 mol/L. The optical properties of H2TEHPPS were investigated based on the UV and fluorescence spectra. The results show that the fluorescence intensity of H2TEHPPS is directly proportional to temperature in the range of 293-353 K So H,TEHPPS can be used as a molecular temoerature sensor in biomedical and other fields.展开更多
文摘Water-soluble porphyrin, as a kind of photosensitive agent and good anticancer modelcompound. may find wide application in the diagnosis and photo-dynamic therapy of can-cer. For its clinical uses. it is very important to elucidate the interaction mechanism ofporphyrin with DNA at molecular level. In 1990. when Turpin et al.studied
文摘A novel water-soluble porphyrin[5,10,15,20-tetra（3-ethoxy-4-hydroxy-5-sulfonate）phenyl porphyrin, H2TEHPPS] was designed and synthesized, which could be used as a potential fluorescence sensor to detect temperature changes. The studies were performed in solution phase and the concentration of H2TEHPPS was 2.0×10^-5 mol/L. The optical properties of H2TEHPPS were investigated based on the UV and fluorescence spectra. The results show that the fluorescence intensity of H2TEHPPS is directly proportional to temperature in the range of 293-353 K So H,TEHPPS can be used as a molecular temoerature sensor in biomedical and other fields.
