在毫米波照射下,目标回波可模型化为多个散射中心回波的合成;宽带线性调频连续波(LFMCW)工作体制可以获得目标多散射中心在雷达径向距离轴上的投影分布,即高距离分辨率目标距离像(high range resolution range profile);综合利用距离像...在毫米波照射下,目标回波可模型化为多个散射中心回波的合成;宽带线性调频连续波(LFMCW)工作体制可以获得目标多散射中心在雷达径向距离轴上的投影分布,即高距离分辨率目标距离像(high range resolution range profile);综合利用距离像所提供的目标多散射中心空间分布和截面积信息,可以改善信号检测和跟踪性能,并完成目标识别。展开更多
Recently, the identification of miRNA targets has received much attention. The strategies to determine miRNA targets include bioinformatic prediction and experimental assays. The bioinformatic prediction methods are m...Recently, the identification of miRNA targets has received much attention. The strategies to determine miRNA targets include bioinformatic prediction and experimental assays. The bioinformatic prediction methods are mainly based on the confirmed rules of interaction between miRNAs and their targets, and are carried out by programs, such as miRanda, TargetScan, TargetScanS, RNAhybrid, DIANA-microT, PicTar, RNA22 and FindTar, which follow well-known principles. The experimental assays to find miRNA targets employ immunoprecipitation of AGO proteins to identify interacting mRNAs, or the analysis of mRNA or protein levels to identify genes which can be regulated by miRNAs. The improvement of current bioinformatic and experimental assays and the development of novel assays will enable greater efficiency in the identification of miRNA targets and thus facilitate miRNA research. This paper describes progress in the prediction and identification of miRNA targets.展开更多
文摘在毫米波照射下,目标回波可模型化为多个散射中心回波的合成;宽带线性调频连续波(LFMCW)工作体制可以获得目标多散射中心在雷达径向距离轴上的投影分布,即高距离分辨率目标距离像(high range resolution range profile);综合利用距离像所提供的目标多散射中心空间分布和截面积信息,可以改善信号检测和跟踪性能,并完成目标识别。
基金Supported by the National Basic Research Program of China (Grant No. 2005CB724600)the National Natural Science Foundation of China (Grant No. 30600110)
文摘Recently, the identification of miRNA targets has received much attention. The strategies to determine miRNA targets include bioinformatic prediction and experimental assays. The bioinformatic prediction methods are mainly based on the confirmed rules of interaction between miRNAs and their targets, and are carried out by programs, such as miRanda, TargetScan, TargetScanS, RNAhybrid, DIANA-microT, PicTar, RNA22 and FindTar, which follow well-known principles. The experimental assays to find miRNA targets employ immunoprecipitation of AGO proteins to identify interacting mRNAs, or the analysis of mRNA or protein levels to identify genes which can be regulated by miRNAs. The improvement of current bioinformatic and experimental assays and the development of novel assays will enable greater efficiency in the identification of miRNA targets and thus facilitate miRNA research. This paper describes progress in the prediction and identification of miRNA targets.
