Three patients with nutcracker syndrome(NCS) were enrolled in the study.Their clinical symptoms mainly included proteinuria and serious varicocele.Color Doppler ultrasound and computed tomography showed that the patie...Three patients with nutcracker syndrome(NCS) were enrolled in the study.Their clinical symptoms mainly included proteinuria and serious varicocele.Color Doppler ultrasound and computed tomography showed that the patients had constricted abdominal aortas,reduced superior mesenteric artery angles,and thinned left renal veins.Patients then underwent left spermatic vein ligation and iliac vein anastomosis.They were checked tliree months after their operation,and results showed that their sperms were improved and their proteinuria disappeared. The color Doppler ultrasound showed new cycle pathways.NCS clinical manifestations are complicated,and need combination diagnosis of symptoms and auxiliary examination to detennine surgical indications.Ligation of spermatic vein and vein anastomosis can be used to treat NCS.展开更多
Aim:To assess the relation of reactive oxygen species(ROS)and antioxidants in the internal spermatic vein blood compared to the peripheral venous blood.Methods:Sixty-eight infertile oligoasthenozoospemic patients asso...Aim:To assess the relation of reactive oxygen species(ROS)and antioxidants in the internal spermatic vein blood compared to the peripheral venous blood.Methods:Sixty-eight infertile oligoasthenozoospemic patients associated with varicocele were investigated.During inguinal varicocelectomy,blood samples of internal sper- matic as well as median cubital veins were withdrawn.Three ROS factors(malondialdehyde[MDA],hydrogen peroxide H_2O_2,nitric oxide[NO])and four antioxidants(superoxide dismutase[SOD],catalase[Cat],glutathione peroxidase[GPx] and vitamin C)were estimated in these blood samples.Results:Mean levels of tested ROS factors were significantly higher in the internal spermatic venous blood compared to those in the peripheral one (mean±SD)(MDA 18.7±1.4 nmol/mL vs.15.4±1.4 nmol/mL,H_2O_2 43.6±8.0 μmol/mL vs.30.8±8.1 μmol/mL,NO 2.3±0.5 nmol/L vs.1.6±0.4 nmol/L,P<0.01).Mean levels of tested antioxidants were significantly lower in the internal spermatic venous blood compared to those in the peripheral one(superoxide dismutase 1690.7±130.0 U/mL vs.1818.5±143.0 U/mL,catalase 38.9±6.1 mol/L vs.47.9±10.2 mol/L,GPx 20.4±8.1 U/mL vs.23.0±8.4 U/mL,vita- min C 0.3±0.1 vs.0.4±0.1 mg/dL,P<0.05).Conclusion:Internal spermatic venous blood of infertile male cases associated with varicocele demonstrated elevated levels of ROS and decreased levels of antioxidants compared to peripheral venous circulation.(Asian J Androl 2006 Jul;8:451-454)展开更多
文摘Three patients with nutcracker syndrome(NCS) were enrolled in the study.Their clinical symptoms mainly included proteinuria and serious varicocele.Color Doppler ultrasound and computed tomography showed that the patients had constricted abdominal aortas,reduced superior mesenteric artery angles,and thinned left renal veins.Patients then underwent left spermatic vein ligation and iliac vein anastomosis.They were checked tliree months after their operation,and results showed that their sperms were improved and their proteinuria disappeared. The color Doppler ultrasound showed new cycle pathways.NCS clinical manifestations are complicated,and need combination diagnosis of symptoms and auxiliary examination to detennine surgical indications.Ligation of spermatic vein and vein anastomosis can be used to treat NCS.
文摘Aim:To assess the relation of reactive oxygen species(ROS)and antioxidants in the internal spermatic vein blood compared to the peripheral venous blood.Methods:Sixty-eight infertile oligoasthenozoospemic patients associated with varicocele were investigated.During inguinal varicocelectomy,blood samples of internal sper- matic as well as median cubital veins were withdrawn.Three ROS factors(malondialdehyde[MDA],hydrogen peroxide H_2O_2,nitric oxide[NO])and four antioxidants(superoxide dismutase[SOD],catalase[Cat],glutathione peroxidase[GPx] and vitamin C)were estimated in these blood samples.Results:Mean levels of tested ROS factors were significantly higher in the internal spermatic venous blood compared to those in the peripheral one (mean±SD)(MDA 18.7±1.4 nmol/mL vs.15.4±1.4 nmol/mL,H_2O_2 43.6±8.0 μmol/mL vs.30.8±8.1 μmol/mL,NO 2.3±0.5 nmol/L vs.1.6±0.4 nmol/L,P<0.01).Mean levels of tested antioxidants were significantly lower in the internal spermatic venous blood compared to those in the peripheral one(superoxide dismutase 1690.7±130.0 U/mL vs.1818.5±143.0 U/mL,catalase 38.9±6.1 mol/L vs.47.9±10.2 mol/L,GPx 20.4±8.1 U/mL vs.23.0±8.4 U/mL,vita- min C 0.3±0.1 vs.0.4±0.1 mg/dL,P<0.05).Conclusion:Internal spermatic venous blood of infertile male cases associated with varicocele demonstrated elevated levels of ROS and decreased levels of antioxidants compared to peripheral venous circulation.(Asian J Androl 2006 Jul;8:451-454)
