Purpose/Hypothesis: To determine if agreement exists between microcurrent conductance through the skin over an injury, myoglobin levels in the serum, and diagnostic ultrasound measurements of swelling. Number of Subje...Purpose/Hypothesis: To determine if agreement exists between microcurrent conductance through the skin over an injury, myoglobin levels in the serum, and diagnostic ultrasound measurements of swelling. Number of Subjects: 140. Materials/Methods: Subject underwent microcurrent conductance, serum myoglobin, diagnostic ultrasound, and strength testing before and after delayed onset muscle soreness (DOMS) was induced. Non-control subjects were also given a therapy wrap, dry heat, moist heat, or cold, either applied immediately or delayed 24 hours. Results: After induction of DOMS, there was agreement between significant 37% decreases in microcurrent conductance, significant 37% serum myoglobin increases, and significant 20% increases in quadriceps size, measured by diagnostic ultrasound. When either dry heat or cold was applied immediately, changes in these measurements were insignificant and less than 10%. Agreement was weaker when treatment was delayed 24 hours. Also, cold packs showed less than a 5% decrease in microcurrent conductance for covered areas compared to a 22% decrease for uncovered areas around the knee with 24 hour delay. Moist heat packs showed an insignificant change overall, but a significant 11% decrease for the covered center of the quadriceps with immediate treatment. Strength decreased 25% after DOMS, and all immediate treatments, along with 24 hour delayed cold and moist heat showed significantly smaller decreases. Conclusions: Changes in microcurrent conductance through the skin over injured tissue appear to be indicative of initial injury and recovery, and also for detecting the specific area of the injury. Clinical Relevance: Microcurrent through the skin over injured tissue appears to be a promising objective measurement of tissue injury as well as recovery from injury.展开更多
目的:探讨剪切波弹性成像定量评估鼻咽癌放疗后颈部软组织纤维化的可行性和临床应用价值。方法:使用法国Supersonic公司的AixPlorer型实时定量剪切波弹性成像诊断仪,分别对30例鼻咽癌放疗后颈部软组织纤维化患者(观察组)和30例同时期体...目的:探讨剪切波弹性成像定量评估鼻咽癌放疗后颈部软组织纤维化的可行性和临床应用价值。方法:使用法国Supersonic公司的AixPlorer型实时定量剪切波弹性成像诊断仪,分别对30例鼻咽癌放疗后颈部软组织纤维化患者(观察组)和30例同时期体检健康者(对照组)颈部软组织进行检测,在相同条件下对比分析两组颈部皮下组织、肌肉、涎腺、甲状腺的杨氏模量值。结果:(1)鼻咽癌放疗后观察组双侧颈部皮下组织、胸锁乳突肌的杨氏模量平均值,与对照组比较各项数值有明显增高:L-Sub 71.74±60.71 vs 11.79±5.74、R-Sub 84.09±87.97 vs 13.54±6.46、L-SCM 85.63±56.32 vs 18.53±5.03、R-SCM 81.02±66.33 vs20.20±5.84,P值均小于0.05,表明鼻咽癌放疗后观察组双侧颈部皮下组织和胸锁乳突肌的质硬度即纤维化有了明显增高;(2)对照组和观察组双侧颈部颌下腺、腮腺、甲状腺的杨氏模量平均值比较:L-subman7.27±1.46 vs 7.73±3.38、R-subman 6.34±1.65 vs 6.18±2.60、L-partotid 5.77±1.25 vs 6.90±3.31、Rpartotid 6.01±1.03 vs 6.91±2.09、L-thy 8.12±2.46 vs 7.87±4.19、R-thy 7.47±2.13 vs 7.81±2.80,P值均大于0.05,提示放疗对涎腺、甲状腺的质硬度或纤维化没有明显的影响。结论:剪切波弹性成像技术具有足够的灵敏度,可客观地量化鼻咽癌放疗后的软组织纤维化,具有定量评价纤维化程度、分级的临床应用潜力。展开更多
文摘Purpose/Hypothesis: To determine if agreement exists between microcurrent conductance through the skin over an injury, myoglobin levels in the serum, and diagnostic ultrasound measurements of swelling. Number of Subjects: 140. Materials/Methods: Subject underwent microcurrent conductance, serum myoglobin, diagnostic ultrasound, and strength testing before and after delayed onset muscle soreness (DOMS) was induced. Non-control subjects were also given a therapy wrap, dry heat, moist heat, or cold, either applied immediately or delayed 24 hours. Results: After induction of DOMS, there was agreement between significant 37% decreases in microcurrent conductance, significant 37% serum myoglobin increases, and significant 20% increases in quadriceps size, measured by diagnostic ultrasound. When either dry heat or cold was applied immediately, changes in these measurements were insignificant and less than 10%. Agreement was weaker when treatment was delayed 24 hours. Also, cold packs showed less than a 5% decrease in microcurrent conductance for covered areas compared to a 22% decrease for uncovered areas around the knee with 24 hour delay. Moist heat packs showed an insignificant change overall, but a significant 11% decrease for the covered center of the quadriceps with immediate treatment. Strength decreased 25% after DOMS, and all immediate treatments, along with 24 hour delayed cold and moist heat showed significantly smaller decreases. Conclusions: Changes in microcurrent conductance through the skin over injured tissue appear to be indicative of initial injury and recovery, and also for detecting the specific area of the injury. Clinical Relevance: Microcurrent through the skin over injured tissue appears to be a promising objective measurement of tissue injury as well as recovery from injury.
文摘目的:探讨剪切波弹性成像定量评估鼻咽癌放疗后颈部软组织纤维化的可行性和临床应用价值。方法:使用法国Supersonic公司的AixPlorer型实时定量剪切波弹性成像诊断仪,分别对30例鼻咽癌放疗后颈部软组织纤维化患者(观察组)和30例同时期体检健康者(对照组)颈部软组织进行检测,在相同条件下对比分析两组颈部皮下组织、肌肉、涎腺、甲状腺的杨氏模量值。结果:(1)鼻咽癌放疗后观察组双侧颈部皮下组织、胸锁乳突肌的杨氏模量平均值,与对照组比较各项数值有明显增高:L-Sub 71.74±60.71 vs 11.79±5.74、R-Sub 84.09±87.97 vs 13.54±6.46、L-SCM 85.63±56.32 vs 18.53±5.03、R-SCM 81.02±66.33 vs20.20±5.84,P值均小于0.05,表明鼻咽癌放疗后观察组双侧颈部皮下组织和胸锁乳突肌的质硬度即纤维化有了明显增高;(2)对照组和观察组双侧颈部颌下腺、腮腺、甲状腺的杨氏模量平均值比较:L-subman7.27±1.46 vs 7.73±3.38、R-subman 6.34±1.65 vs 6.18±2.60、L-partotid 5.77±1.25 vs 6.90±3.31、Rpartotid 6.01±1.03 vs 6.91±2.09、L-thy 8.12±2.46 vs 7.87±4.19、R-thy 7.47±2.13 vs 7.81±2.80,P值均大于0.05,提示放疗对涎腺、甲状腺的质硬度或纤维化没有明显的影响。结论:剪切波弹性成像技术具有足够的灵敏度,可客观地量化鼻咽癌放疗后的软组织纤维化,具有定量评价纤维化程度、分级的临床应用潜力。
