Obstructive sleep apnea syndrome (OSAS) increases the risk of post-surgery complications. This study uses Berlin Questionnaire (BQ) to identify Chinese adult surgical patients who are at a high risk of OSAS and to...Obstructive sleep apnea syndrome (OSAS) increases the risk of post-surgery complications. This study uses Berlin Questionnaire (BQ) to identify Chinese adult surgical patients who are at a high risk of OSAS and to determine if the BQ could be used to detect potential high risk of adverse respiratory events in the post anesthesia care unit (PACU). Results indicated that only 11.4% of the patients were considered at a high risk of OSAS. Age and body mass index are the key factors for the risk of OSAS prevalence in China and also gender specific. Furthermore, the incidence of adverse respiratory events in the PACU was higher in patients with high risk of OSAS than others (6.8% vs. 0.9%, P 〈 0.001). They also stayed longer than others in the PACU (95 ~ 28 min vs. 62 ~ 19 min, P 〈 0.001). Age, high risk for OSAS, and smoking were independent risk factors for the occurrence of adverse respiratory events in the PACU. The BQ may be adopted as a screening tool for anesthesiologists in China to identify patients who are at high risk of OSAS and determine the potential risk of developing postoperative respiratory complications in the PACU.展开更多
目的探讨青年OSAHS患者缺氧程度与认知功能的相关性。方法选取OSAHS患者63例,年龄18~44岁。根据OSAHS患者的低氧血症程度,将患者分为轻度组20例(最低SaO2≥85%),中度组24例(最低SaO265%~84%),重度组19例(最低SaO2<65%);对照组25例...目的探讨青年OSAHS患者缺氧程度与认知功能的相关性。方法选取OSAHS患者63例,年龄18~44岁。根据OSAHS患者的低氧血症程度,将患者分为轻度组20例(最低SaO2≥85%),中度组24例(最低SaO265%~84%),重度组19例(最低SaO2<65%);对照组25例(正常人:AHI<5)。均进行事件相关电位P300、多导睡眠图(polysomnogram,PSG)和简易智能精神状态检查量表(mini-mental state examination,MMSE)检测。结果①OSAHS患者轻度、中度、重度三组P300潜伏期分别为326.1±12.7、346.9±19.1、334.9±18.3ms,与对照组311.9±18.3ms比较差异均有统计学意义(皆P<0.05),OSAHS轻、中度组与重度组之间差异均有统计学意义(P<0.01或P<0.05),但轻度组和中度组患者之间差异无统计学意义(P=0.095);②重度组中因最低血氧持续时间的不同P300潜伏期不同:最低血氧持续时间4~60秒组潜伏期为338.12±13.7ms,最低血氧持续时间61~140秒组潜伏期为354.74±16.7ms,差异有统计学意义(P=0.031);③以上各组P300波幅之间比较差异无统计学意义;④所有患者MESS得分均在正常范围内,但部分得分稍低,重度组与对照组得分比较差异有统计学意义(R-A-R-B=9.91,P=0.003)。结论OSAHS患者普遍存在认知功能障碍,可以最低血氧程度及其持续时间初步评估认知功能损害的程度。展开更多
文摘Obstructive sleep apnea syndrome (OSAS) increases the risk of post-surgery complications. This study uses Berlin Questionnaire (BQ) to identify Chinese adult surgical patients who are at a high risk of OSAS and to determine if the BQ could be used to detect potential high risk of adverse respiratory events in the post anesthesia care unit (PACU). Results indicated that only 11.4% of the patients were considered at a high risk of OSAS. Age and body mass index are the key factors for the risk of OSAS prevalence in China and also gender specific. Furthermore, the incidence of adverse respiratory events in the PACU was higher in patients with high risk of OSAS than others (6.8% vs. 0.9%, P 〈 0.001). They also stayed longer than others in the PACU (95 ~ 28 min vs. 62 ~ 19 min, P 〈 0.001). Age, high risk for OSAS, and smoking were independent risk factors for the occurrence of adverse respiratory events in the PACU. The BQ may be adopted as a screening tool for anesthesiologists in China to identify patients who are at high risk of OSAS and determine the potential risk of developing postoperative respiratory complications in the PACU.
文摘目的探讨青年OSAHS患者缺氧程度与认知功能的相关性。方法选取OSAHS患者63例,年龄18~44岁。根据OSAHS患者的低氧血症程度,将患者分为轻度组20例(最低SaO2≥85%),中度组24例(最低SaO265%~84%),重度组19例(最低SaO2<65%);对照组25例(正常人:AHI<5)。均进行事件相关电位P300、多导睡眠图(polysomnogram,PSG)和简易智能精神状态检查量表(mini-mental state examination,MMSE)检测。结果①OSAHS患者轻度、中度、重度三组P300潜伏期分别为326.1±12.7、346.9±19.1、334.9±18.3ms,与对照组311.9±18.3ms比较差异均有统计学意义(皆P<0.05),OSAHS轻、中度组与重度组之间差异均有统计学意义(P<0.01或P<0.05),但轻度组和中度组患者之间差异无统计学意义(P=0.095);②重度组中因最低血氧持续时间的不同P300潜伏期不同:最低血氧持续时间4~60秒组潜伏期为338.12±13.7ms,最低血氧持续时间61~140秒组潜伏期为354.74±16.7ms,差异有统计学意义(P=0.031);③以上各组P300波幅之间比较差异无统计学意义;④所有患者MESS得分均在正常范围内,但部分得分稍低,重度组与对照组得分比较差异有统计学意义(R-A-R-B=9.91,P=0.003)。结论OSAHS患者普遍存在认知功能障碍,可以最低血氧程度及其持续时间初步评估认知功能损害的程度。