The physical models of the outer and inner half coil jackets were simplified to two types of coiled ducts.The mathematic models of incompressible fluid at the condition of laminar flow and heat transfer in the two typ...The physical models of the outer and inner half coil jackets were simplified to two types of coiled ducts.The mathematic models of incompressible fluid at the condition of laminar flow and heat transfer in the two types of jackets for cooling process reactor were set up and solved by the semi-implicit method for pressure linked equa-tions consistent （SIMPLEC） algorithm based on a control volume method.The flow and temperature fields were given and the effects of Dean and Prandtl numbers on flow and heat transfer were studied.The results show that flow in the inner half coil jacket is found to exhibit transition of secondary flow pattern from two vortices to four vortices when the Dean number increases,but that in the outer half coil jacket is not found.The critical Dean num-ber is about 96.The inner half coil jacket has stronger heat transfer ability than the outer half coil jacket and this superiority is more evident with larger Prandtl number.However,as the Dean number is greater than 105,the flow resistance enhances more severely in the inner jacket than the outer jacket.For both jackets,the centers of the heated wall are the poorest for heat transfer.展开更多
Simultaneous development of the laminar flow and heat transfer in helicalsquare ducts was numerically studied. The governing equations were written in an orthogonal helicalcoordinate system and fully parabolized in th...Simultaneous development of the laminar flow and heat transfer in helicalsquare ducts was numerically studied. The governing equations were written in an orthogonal helicalcoordinate system and fully parabolized in the axial direction. Results were found out over a widerange of the governing parameters. Two axial velocity entries were taken into account. Thedevelopment of secondary flow, axial velocity and temperature distribution for the large Dean numberwere examined in detail and the effects of different governing parameters on the friction factorand- the Nusselt number were annlyzee. Many new and interesting conclusions were reached. Thepresent results reveal the nature of fluid flow and heat transfer in the developing region ofhelical square ducts.展开更多
Li[Li0.2Ni0.13Coo.13Mn0.54]O2 cathode materials were synthesized by carbonate-based co-precipitation method, and then, its surface was coated by thin layers of FePO4. The prepared samples were characterized by X-ray d...Li[Li0.2Ni0.13Coo.13Mn0.54]O2 cathode materials were synthesized by carbonate-based co-precipitation method, and then, its surface was coated by thin layers of FePO4. The prepared samples were characterized by X-ray diffraction （XRD）, field emission scanning electron micro- scope （FESEM）, energy-dispersive spectroscopy （EDS）, and transmission electron microscopy （TEM）. The XRD and TEM results suggest that both the pristine and the coated materials have a hexagonal layered structure, and the FePO4 coating layer does not make any major change in the crystal structure. The FePO4-coated sample exhibits both improved initial discharge capacity and columbic efficiency compared to the pristine one. More significantly, the FePO4 coating layer has a much positive influence on the cycling perfor- mance. The FePO4-coated sample exhibits capacity reten- tion of 82 % after 100 cycles at 0.5℃ between 2.0 and 4.8 V, while only 28 % for the pristine one at the same charge-discharge condition. The electrochemical impe- dance spectroscopy （EIS） results indicate that this improved cycling performance could be ascribed to the presence of FePO4 on the surface of Li[Li0.2Ni0.13Co0.13Mno.54102 par- ticle, which helps to protect the cathode from chemical attacks by HF and thus suppresses the large increase in charge transfer resistance.展开更多
Transfer RNA(t RNA)-derived small RNAs(ts RNAs) are a recently established family of regulatory small non-coding RNAs that modulate diverse biological processes. Growing evidence indicates that ts RNAs are involved in...Transfer RNA(t RNA)-derived small RNAs(ts RNAs) are a recently established family of regulatory small non-coding RNAs that modulate diverse biological processes. Growing evidence indicates that ts RNAs are involved in neurological disorders and play a role in the pathogenesis of neurodegenerative disease. However, whether ts RNAs are involved in traumatic brain injury-induced secondary injury remains poorly understood. In this study, a mouse controlled cortical impact model of traumatic brain injury was established, and integrated ts RNA and messenger RNA(m RNA) transcriptome sequencing were used. The results revealed that 103 ts RNAs were differentially expressed in the mouse model of traumatic brain injury at 72 hours, of which 56 ts RNAs were upregulated and 47 ts RNAs were downregulated. Based on micro RNA-like seed matching and Pearson correlation analysis, 57 differentially expressed ts RNA-m RNA interaction pairs were identified, including 29 ts RNAs and 26 m RNAs. Moreover, Gene Ontology annotation of target genes revealed that the significantly enriched terms were primarily associated with inflammation and synaptic function. Collectively, our findings suggest that ts RNAs may be associated with traumatic brain injury-induced secondary brain injury, and are thus a potential therapeutic target for traumatic brain injury. The study was approved by the Beijing Neurosurgical Institute Animal Care and Use Committee(approval No. 20190411) on April 11, 2019.展开更多
基金Supported by the National Key Technologies Research and Development Program during the 10th Five-year Plan Period(2004BA319B1)the Educational Commission of Liaoning Province of China(2008S117)
文摘The physical models of the outer and inner half coil jackets were simplified to two types of coiled ducts.The mathematic models of incompressible fluid at the condition of laminar flow and heat transfer in the two types of jackets for cooling process reactor were set up and solved by the semi-implicit method for pressure linked equa-tions consistent （SIMPLEC） algorithm based on a control volume method.The flow and temperature fields were given and the effects of Dean and Prandtl numbers on flow and heat transfer were studied.The results show that flow in the inner half coil jacket is found to exhibit transition of secondary flow pattern from two vortices to four vortices when the Dean number increases,but that in the outer half coil jacket is not found.The critical Dean num-ber is about 96.The inner half coil jacket has stronger heat transfer ability than the outer half coil jacket and this superiority is more evident with larger Prandtl number.However,as the Dean number is greater than 105,the flow resistance enhances more severely in the inner jacket than the outer jacket.For both jackets,the centers of the heated wall are the poorest for heat transfer.
文摘Simultaneous development of the laminar flow and heat transfer in helicalsquare ducts was numerically studied. The governing equations were written in an orthogonal helicalcoordinate system and fully parabolized in the axial direction. Results were found out over a widerange of the governing parameters. Two axial velocity entries were taken into account. Thedevelopment of secondary flow, axial velocity and temperature distribution for the large Dean numberwere examined in detail and the effects of different governing parameters on the friction factorand- the Nusselt number were annlyzee. Many new and interesting conclusions were reached. Thepresent results reveal the nature of fluid flow and heat transfer in the developing region ofhelical square ducts.
基金financially supported by the National Nature Science Foundation of China (No.51302017)the National High Technology Research and Development Program of China (No.2012AA110102)the fund from the Science and Technology Commission of Beijing (No.2121100006712002)
文摘Li[Li0.2Ni0.13Coo.13Mn0.54]O2 cathode materials were synthesized by carbonate-based co-precipitation method, and then, its surface was coated by thin layers of FePO4. The prepared samples were characterized by X-ray diffraction （XRD）, field emission scanning electron micro- scope （FESEM）, energy-dispersive spectroscopy （EDS）, and transmission electron microscopy （TEM）. The XRD and TEM results suggest that both the pristine and the coated materials have a hexagonal layered structure, and the FePO4 coating layer does not make any major change in the crystal structure. The FePO4-coated sample exhibits both improved initial discharge capacity and columbic efficiency compared to the pristine one. More significantly, the FePO4 coating layer has a much positive influence on the cycling perfor- mance. The FePO4-coated sample exhibits capacity reten- tion of 82 % after 100 cycles at 0.5℃ between 2.0 and 4.8 V, while only 28 % for the pristine one at the same charge-discharge condition. The electrochemical impe- dance spectroscopy （EIS） results indicate that this improved cycling performance could be ascribed to the presence of FePO4 on the surface of Li[Li0.2Ni0.13Co0.13Mno.54102 par- ticle, which helps to protect the cathode from chemical attacks by HF and thus suppresses the large increase in charge transfer resistance.
基金supported by grants from the National Natural Science Foundation of China,Nos.81471238,81771327Construction of Central Nervous System Injury Basic Science and Clinical Translational Research Platform,Budget of Beijing Municipal Health Commission 2020,No.PXM2020_026280_000002(all to BYL)。
文摘Transfer RNA(t RNA)-derived small RNAs(ts RNAs) are a recently established family of regulatory small non-coding RNAs that modulate diverse biological processes. Growing evidence indicates that ts RNAs are involved in neurological disorders and play a role in the pathogenesis of neurodegenerative disease. However, whether ts RNAs are involved in traumatic brain injury-induced secondary injury remains poorly understood. In this study, a mouse controlled cortical impact model of traumatic brain injury was established, and integrated ts RNA and messenger RNA(m RNA) transcriptome sequencing were used. The results revealed that 103 ts RNAs were differentially expressed in the mouse model of traumatic brain injury at 72 hours, of which 56 ts RNAs were upregulated and 47 ts RNAs were downregulated. Based on micro RNA-like seed matching and Pearson correlation analysis, 57 differentially expressed ts RNA-m RNA interaction pairs were identified, including 29 ts RNAs and 26 m RNAs. Moreover, Gene Ontology annotation of target genes revealed that the significantly enriched terms were primarily associated with inflammation and synaptic function. Collectively, our findings suggest that ts RNAs may be associated with traumatic brain injury-induced secondary brain injury, and are thus a potential therapeutic target for traumatic brain injury. The study was approved by the Beijing Neurosurgical Institute Animal Care and Use Committee(approval No. 20190411) on April 11, 2019.
