Detecting differential expression of genes in genom research(e.g.,2019-nCoV)is not uncommon,due to the cost only small sample is employed to estimate a large number of variances(or their inverse)of variables simultane...Detecting differential expression of genes in genom research(e.g.,2019-nCoV)is not uncommon,due to the cost only small sample is employed to estimate a large number of variances(or their inverse)of variables simultaneously.However,the commonly used approaches perform unreliable.Borrowing information across different variables or priori information of variables,shrinkage estimation approaches are proposed and some optimal shrinkage estimators are obtained in the sense of asymptotic.In this paper,we focus on the setting of small sample and a likelihood-unbiased estimator for power of variances is given under the assumption that the variances are chi-squared distribution.Simulation reports show that the likelihood-unbiased estimators for variances and their inverse perform very well.In addition,application comparison and real data analysis indicate that the proposed estimator also works well.展开更多
<span style="font-family:Verdana;">In the applications of Tobit regression models we always encounter the data sets which contain too many variables that only a few of them contribute to the model. The...<span style="font-family:Verdana;">In the applications of Tobit regression models we always encounter the data sets which contain too many variables that only a few of them contribute to the model. Therefore, it will waste much more samples to estimate the “non-effective” variables in the inference. In this paper, we use a sequential procedure for constructing the fixed size confidence set for the “effective” parameters to the model by using an adaptive shrinkage estimate such that the “effective” coefficients can be efficiently identified with the minimum sample size based on Tobit regression model. Fixed design is considered for numerical simulation.</span>展开更多
基金Supported by the National Natural Science Foundation of China(11971433)First Class Discipline of Zhejiang-A(Zhejiang Gongshang University-Statistics)Hunan Soft Science Research Project(2012ZK3064)
文摘Detecting differential expression of genes in genom research(e.g.,2019-nCoV)is not uncommon,due to the cost only small sample is employed to estimate a large number of variances(or their inverse)of variables simultaneously.However,the commonly used approaches perform unreliable.Borrowing information across different variables or priori information of variables,shrinkage estimation approaches are proposed and some optimal shrinkage estimators are obtained in the sense of asymptotic.In this paper,we focus on the setting of small sample and a likelihood-unbiased estimator for power of variances is given under the assumption that the variances are chi-squared distribution.Simulation reports show that the likelihood-unbiased estimators for variances and their inverse perform very well.In addition,application comparison and real data analysis indicate that the proposed estimator also works well.
文摘<span style="font-family:Verdana;">In the applications of Tobit regression models we always encounter the data sets which contain too many variables that only a few of them contribute to the model. Therefore, it will waste much more samples to estimate the “non-effective” variables in the inference. In this paper, we use a sequential procedure for constructing the fixed size confidence set for the “effective” parameters to the model by using an adaptive shrinkage estimate such that the “effective” coefficients can be efficiently identified with the minimum sample size based on Tobit regression model. Fixed design is considered for numerical simulation.</span>
