Optical imaging has served as a primary method to collect information about biosystems across scales—from functionalities of tissues to morphological structures of cells and even at biomolecular levels.However,to ade...Optical imaging has served as a primary method to collect information about biosystems across scales—from functionalities of tissues to morphological structures of cells and even at biomolecular levels.However,to adequately characterize a complex biosystem,an imaging system with a number of resolvable points,referred to as a space-bandwidth product(SBP),in excess of one billion is typically needed.Since a gigapixel-scale far exceeds the capacity of current optical imagers,compromises must be made to obtain either a low spatial resolution or a narrow field-of-view(FOV).The problem originates from constituent refractive optics—the larger the aperture,the more challenging the correction of lens aberrations.Therefore,it is impractical for a conventional optical imaging system to achieve an SBP over hundreds of millions.To address this unmet need,a variety of high-SBP imagers have emerged over the past decade,enabling an unprecedented resolution and FOV beyond the limit of conventional optics.We provide a comprehensive survey of high-SBP imaging techniques,exploring their underlying principles and applications in bioimaging.展开更多
Due to the influence of shock wave and turbulence, supersonic density field exhibits strongly inhomogeneous and unsteady characteristics. Applying traditional density field measurement techniques to supersonic flows y...Due to the influence of shock wave and turbulence, supersonic density field exhibits strongly inhomogeneous and unsteady characteristics. Applying traditional density field measurement techniques to supersonic flows yields three problems: low spatiotemporal resolution, limitation of measuring 3D density field, and low signal to noise ratio (SNR). A new method based on Nano-based Planar Laser Scattering (NPLS) technique is proposed in this paper to measure supersonic density field. This method measures planar transient density field in 3D supersonic flow by calibrating the relationship between density and concentration of tracer particles, which would display the density fluctuation due to the influence of shock waves and vortexes. The application of this new method to density field measurement of supersonic optical bow cap is introduced in this paper, and the results reveal shock wave, turbulent boundary layer in the flow with the spatial resolution of 93.2 μm/pixel. By analyzing the results at interval of 5 μs, temporal evolution of density field can be observed.展开更多
Landslide is one of the multitudinous serious geological hazards. The key to its control and reduction lies on dynamic monitoring and early warning. The article points out the insufficiency of traditional measuring me...Landslide is one of the multitudinous serious geological hazards. The key to its control and reduction lies on dynamic monitoring and early warning. The article points out the insufficiency of traditional measuring means applied for large-scale landslide monitoring and proposes the method for extensive landslide displacement field monitoring using high- resolution remote images. Matching of cognominal points is realized by using the invariant features of SIFT algorithm in image translation, rotation, zooming, and affine transformation, and through recognition and comparison of characteristics of high-resolution images in different landsliding periods. Following that, landslide displacement vector field can be made known by measuring the distances and directions between cognominal points. As evidenced by field application of the method for landslide monitoring at West Open Mine in Fushun city of China, the method has the attraction of being able to make areal measurement through satellite observation and capable of obtaining at the same time the information of large- area intensive displacement field, for facilitating automatic delimitation of extent of landslide displacement vector field and sliding mass. This can serve as a basis for making analysis of laws governing occurrence of landslide and adoption of countermeasures.展开更多
The optimization of velocity field is the core issue in reservoir seismic pressure prediction. For a long time, the seismic processing velocity analysis method has been used in the establishment of pressure prediction...The optimization of velocity field is the core issue in reservoir seismic pressure prediction. For a long time, the seismic processing velocity analysis method has been used in the establishment of pressure prediction velocity field, which has a long research period and low resolution and restricts the accuracy of seismic pressure prediction;This paper proposed for the first time the use of machine learning algorithms, based on the feasibility analysis of wellbore logging pressure prediction, to integrate the CVI velocity inversion field, velocity sensitive post stack attribute field, and AVO P-wave and S-wave velocity reflectivity to obtain high-precision seismic P and S wave velocities. On this basis, high-resolution formation pore pressure and other parameters prediction based on multi waves is carried out. The pressure prediction accuracy is improved by more than 50% compared to the P-wave resolution of pore pressure prediction using only root mean square velocity. Practice has proven that the research method has certain reference significance for reservoir pore pressure prediction.展开更多
Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously anal...Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.展开更多
In this paper we will summarize the progress in the development of the Chinese Space Solar Telescope (SST) during the past few years. The main scientific objective of SST is to observe the fundamental structure of sol...In this paper we will summarize the progress in the development of the Chinese Space Solar Telescope (SST) during the past few years. The main scientific objective of SST is to observe the fundamental structure of solar magnetic field with its 1-m optical telescope. The success of 1-m Swedish Solar Telescope and Hinode underscores the importance of this 1-m space telescope. In addition, some key technical problems have been solved.展开更多
基金supported partially by the National Institutes of Health(R01EY029397,R35GM128761)the National Science Foundation(1652150)+1 种基金support from the Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(2019R1A6A3A03031505)support from the National Science Foundation(1846784)。
文摘Optical imaging has served as a primary method to collect information about biosystems across scales—from functionalities of tissues to morphological structures of cells and even at biomolecular levels.However,to adequately characterize a complex biosystem,an imaging system with a number of resolvable points,referred to as a space-bandwidth product(SBP),in excess of one billion is typically needed.Since a gigapixel-scale far exceeds the capacity of current optical imagers,compromises must be made to obtain either a low spatial resolution or a narrow field-of-view(FOV).The problem originates from constituent refractive optics—the larger the aperture,the more challenging the correction of lens aberrations.Therefore,it is impractical for a conventional optical imaging system to achieve an SBP over hundreds of millions.To address this unmet need,a variety of high-SBP imagers have emerged over the past decade,enabling an unprecedented resolution and FOV beyond the limit of conventional optics.We provide a comprehensive survey of high-SBP imaging techniques,exploring their underlying principles and applications in bioimaging.
基金Supported by the National Natural Science Foundation of China (Grant No. 10672178)
文摘Due to the influence of shock wave and turbulence, supersonic density field exhibits strongly inhomogeneous and unsteady characteristics. Applying traditional density field measurement techniques to supersonic flows yields three problems: low spatiotemporal resolution, limitation of measuring 3D density field, and low signal to noise ratio (SNR). A new method based on Nano-based Planar Laser Scattering (NPLS) technique is proposed in this paper to measure supersonic density field. This method measures planar transient density field in 3D supersonic flow by calibrating the relationship between density and concentration of tracer particles, which would display the density fluctuation due to the influence of shock waves and vortexes. The application of this new method to density field measurement of supersonic optical bow cap is introduced in this paper, and the results reveal shock wave, turbulent boundary layer in the flow with the spatial resolution of 93.2 μm/pixel. By analyzing the results at interval of 5 μs, temporal evolution of density field can be observed.
文摘Landslide is one of the multitudinous serious geological hazards. The key to its control and reduction lies on dynamic monitoring and early warning. The article points out the insufficiency of traditional measuring means applied for large-scale landslide monitoring and proposes the method for extensive landslide displacement field monitoring using high- resolution remote images. Matching of cognominal points is realized by using the invariant features of SIFT algorithm in image translation, rotation, zooming, and affine transformation, and through recognition and comparison of characteristics of high-resolution images in different landsliding periods. Following that, landslide displacement vector field can be made known by measuring the distances and directions between cognominal points. As evidenced by field application of the method for landslide monitoring at West Open Mine in Fushun city of China, the method has the attraction of being able to make areal measurement through satellite observation and capable of obtaining at the same time the information of large- area intensive displacement field, for facilitating automatic delimitation of extent of landslide displacement vector field and sliding mass. This can serve as a basis for making analysis of laws governing occurrence of landslide and adoption of countermeasures.
文摘The optimization of velocity field is the core issue in reservoir seismic pressure prediction. For a long time, the seismic processing velocity analysis method has been used in the establishment of pressure prediction velocity field, which has a long research period and low resolution and restricts the accuracy of seismic pressure prediction;This paper proposed for the first time the use of machine learning algorithms, based on the feasibility analysis of wellbore logging pressure prediction, to integrate the CVI velocity inversion field, velocity sensitive post stack attribute field, and AVO P-wave and S-wave velocity reflectivity to obtain high-precision seismic P and S wave velocities. On this basis, high-resolution formation pore pressure and other parameters prediction based on multi waves is carried out. The pressure prediction accuracy is improved by more than 50% compared to the P-wave resolution of pore pressure prediction using only root mean square velocity. Practice has proven that the research method has certain reference significance for reservoir pore pressure prediction.
基金supported by National Key R&D Program of China(grant no.2022YFC2404201)the Chinese Academy of Sciences Project for Young Scientists in Basic Research(grant no.YSBR067).
文摘Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.
基金Supported by the Important Directional Project of Chinese Academy of Sciences (Grant No. KJCX2-YW-T04)the National Basic Research Program of China (Grant No. 2006CB806301)the National Natural Science Foundation of China (Grant Nos. 10878004, 10733020, and10673016)
文摘In this paper we will summarize the progress in the development of the Chinese Space Solar Telescope (SST) during the past few years. The main scientific objective of SST is to observe the fundamental structure of solar magnetic field with its 1-m optical telescope. The success of 1-m Swedish Solar Telescope and Hinode underscores the importance of this 1-m space telescope. In addition, some key technical problems have been solved.
