In the present paper,a homogenization-based two-scale FEM-FEM model is developed to simulate compactions of visco-plastic granular assemblies.The granular structure consisting of two-dimensional grains is modeled by t...In the present paper,a homogenization-based two-scale FEM-FEM model is developed to simulate compactions of visco-plastic granular assemblies.The granular structure consisting of two-dimensional grains is modeled by the microscopic finite element method at the small-scale level,and the homogenized viscous assembly is analyzed by the macroscopic finite element method at large-scale level.The link between scales is made using a computational homogenization method.The two-scale FEM-FEM model is developed in which each particle is treated individually with the appropriate constitutive relations obtained from a representative volume element,kinematic conditions,contact constraints,and elimination of overlap satisfied for every particle.The method could be used in a variety of problems that can be represented using granular media.展开更多
Hydrogels have drawn considerable attention in the past two decades due to their excellent biocompatibility and multi-stimuli responsiveness. They have a wide range of applications in the fields related to tissue engi...Hydrogels have drawn considerable attention in the past two decades due to their excellent biocompatibility and multi-stimuli responsiveness. They have a wide range of applications in the fields related to tissue engineering, sensors and biomedicine. Their applications are strongly influenced by the surface properties of hydrogels and the interfacial interactions between hydrogels and other substrates. In particular, the surface wettability and adhesion of hydrogels decide their applications as drug carriers and wound dressing materials. Nevertheless, there is a lack of systematic discussion on the surface functionalization strategies of hydrogels. Therefore, this review aims at summarizing the strategies of functionalizing the surfaces of hydrogels and bonding hydrogels with other solid substrates. It also explores the challenges and future perspectives of interfacial engineering of hydrogels.展开更多
基金This work was supported by National Natural Science Foundation of China(Grant No.10972162).
文摘In the present paper,a homogenization-based two-scale FEM-FEM model is developed to simulate compactions of visco-plastic granular assemblies.The granular structure consisting of two-dimensional grains is modeled by the microscopic finite element method at the small-scale level,and the homogenized viscous assembly is analyzed by the macroscopic finite element method at large-scale level.The link between scales is made using a computational homogenization method.The two-scale FEM-FEM model is developed in which each particle is treated individually with the appropriate constitutive relations obtained from a representative volume element,kinematic conditions,contact constraints,and elimination of overlap satisfied for every particle.The method could be used in a variety of problems that can be represented using granular media.
基金financially supported by the National Natural Science Foundation of China(No.21574004)Xiamen Southern Oceanographic Center(No.14GQT61HJ31)+3 种基金the 111 project(No.B14009)the Fundamental Research Funds for the Central Universitiesthe National ‘Young Thousand Talents Program’the Academic Excellence Foundation of BUAA for PHD Students
文摘Hydrogels have drawn considerable attention in the past two decades due to their excellent biocompatibility and multi-stimuli responsiveness. They have a wide range of applications in the fields related to tissue engineering, sensors and biomedicine. Their applications are strongly influenced by the surface properties of hydrogels and the interfacial interactions between hydrogels and other substrates. In particular, the surface wettability and adhesion of hydrogels decide their applications as drug carriers and wound dressing materials. Nevertheless, there is a lack of systematic discussion on the surface functionalization strategies of hydrogels. Therefore, this review aims at summarizing the strategies of functionalizing the surfaces of hydrogels and bonding hydrogels with other solid substrates. It also explores the challenges and future perspectives of interfacial engineering of hydrogels.
