Our analysis of fog and haze observations from the surface weather stations in China in recent 50 years （from 196l to 2011） shows that the number of fog days has experienced two-stage variations, with an increasing ...Our analysis of fog and haze observations from the surface weather stations in China in recent 50 years （from 196l to 2011） shows that the number of fog days has experienced two-stage variations, with an increasing trend before 1980 and a decreasing trend after 1990. Especially, an obvious decreasing trend after 1990 can be clearly seen, which is consistent with the decreas- ing trend of the surface relative humidity. However, the number of haze days has demonstrated an increasing trend. As such, the role of reduction of atmospheric relative humidity in the transition process from fog into haze has been further investigated. It is estimated that the mean relative humidity of haze days is about 69%, lower than previously estimated, which implies that it is more difficult for the haze particles to transform into fog drops. This is possibly one of the major environmental factors leading to the reduction of number of fog days. The threshold of the relative humidity for transition from fog into haze is about 82%, also lower than previously estimated. Thus, the reduction of the surface relative humidity in China mainly due to the in- crease of the surface temperature and the saturation specific humidity may exert an obvious impact on the environmental con- ditions for the formations of fog and haze. In addition, our investigation of the relationship between haze and visibility reveals that with the increase of haze days, the visibility has declined markedly. Since 1961, the mean visibility has dropped from 4-10 to 2-4 kin, about a half of the previous horizontal distance of visibility.展开更多
Objective To estimate the relative risks of dyslipidemia, hypertension, diabetes mellitus, and metabolic syndromes among overweight and obese Chinese children compared with their normal weight counterparts. Methods Ov...Objective To estimate the relative risks of dyslipidemia, hypertension, diabetes mellitus, and metabolic syndromes among overweight and obese Chinese children compared with their normal weight counterparts. Methods Overweight and obesity were defined by age- and sex-specific BMI classification reference for Chinese children and adolescents. Pediatric metabolic syndrome （MetS） and each risk factor for MetS were defined using the criteria for US adolescents. Definition of hyper-TC, LDL, and dyslipidemia for adults was applied as well. General linear model factor analysis and chi-square test were used to compare the difference in metabolic indicators among normal weight, overweight, and obese groups. Multiple logistic regression analysis was performed to estimate the odds ratio of metabolic abnormalities between obesity, overweight, and normal weight children, after adjustment for living area, family economic level, age, sex, and daily exercise time and TV watching time, as well as different dietary indices in the model. Results Significant increases in blood lipids, glucose, and blood pressure were found among overweight and obese children as compared with their counterparts with normal weight. By applying WGOC-recommended BMI classification, the risks for hypertriglyceridemia, low HDL and dyslipidemia among overweight children were 1.9, 1.4, and 1.5 times, and was 3.3, 1.5, and 1.8 times among obese groups compared to their counterparts with normal weight after adjustment for age, sex, region, socioeconomic status, physical activity, and dietary intakes. The overweight and obese children （15-17.9 years） had a high-risk of developing hypertension, which was 2.3 and 2.9 times higher than their counterparts with normal weight. Above 90% obese adolescents had abdominal obesity, while less than 1% normal weight ones had abdominal obesity. No obese adolescents were free from any risk factors for MetS, while 36.9% of normal weight adolescents were from the risk factors. 83.3% obese boys and all obese girls had me展开更多
An intensive field campaign including measurements from the environmental monitoring network and from two super sites took place in the Pearl River Delta region in summer 2006.Using routinely measured O3 and NOx conce...An intensive field campaign including measurements from the environmental monitoring network and from two super sites took place in the Pearl River Delta region in summer 2006.Using routinely measured O3 and NOx concentrations,the spatial and temporal variation of O3 and of the total oxidant concentrations was characterized.According to the spatial variability of NO2/NO,the two super sites were found to be representative of polluted urban and downwind suburban conditions.In addition,both sites were located in high O3 regions.In-depth diagnostic of photochemical ozone production processes and their key controlling factors are achieved with an observation-based model(OBM) to gain regional perspectives.Budget analysis and sensitivity model runs show that aldehyde and HONO chemistry had significant impacts on local photochemical ozone production rates.The analysis of calculated Relative Incremental Reactivities shows that photochemical ozone production rates are mainly sensitive to anthropogenic hydrocarbons(HCs) in the polluted urban areas.In the suburban areas,sensitivity to nitrogen oxide(NO) concentrations dominated.Key anthropogenic HCs in both areas are alkenes and aromatics.Significant differences of ozone production efficiencies are identified between the urban and suburban regions,consistent with the OBM diagnosed results.展开更多
Drought is one of the major natural disasters causing huge agricultural losses annually. Regional agricultural drought risk assessment has great significance for reducing regional disaster and agricultural drought los...Drought is one of the major natural disasters causing huge agricultural losses annually. Regional agricultural drought risk assessment has great significance for reducing regional disaster and agricultural drought losses. Based on the fuzzy characteristics of agricultural drought risk, variable fuzzy sets model was used for comprehensively assessing agricultural drought risk of Liaoning Province in China. A multi-layers and multi-indices assessment model was estab-lished according to variable fuzzy sets theory, and agricultural drought risk of all 14 prefecture-level cities was respec-tively estimated in terms of dangerousness, vulnerability, exposure and drought-resistibility. By calculating the combi-nation weights of four drought risk factors, agricultural drought risk grade of each city was obtained. Based on the as-sessment results, the spatial distribution maps of agricultural drought risk were drawn. The results shows that eastern cities have lower drought dangerousness than western cities in Liaoning Province totally. Most cities are located in low drought vulnerability region and high drought exposure region. Because of frequent and severe drought since 2000, most cities are located in lower drought-resistibility region. Comprehensive agricultural drought risk presents apparent spatial characteristics, escalating from the east to the west. Drought dangerousness is the most important factor influencing comprehensive agricultural drought risk. Through the spatial distribution maps of drought risk, decision makers could find out drought situation and make decisions on drought resistance conveniently.展开更多
The effect of water temperature on gut mass and digestive enzyme activity in sea cucumber Apostichopusjaponicus, including relative gut mass （RGM）, amylase, lipase, pepsin and trypsin activities were studied at temp...The effect of water temperature on gut mass and digestive enzyme activity in sea cucumber Apostichopusjaponicus, including relative gut mass （RGM）, amylase, lipase, pepsin and trypsin activities were studied at temperatures of 7, 14, 21, and 28℃ over a period of 40 days. Results show that RGM significantly decreased after 40 days at 21 ℃ and markedly decreased over the whole experiment period at 28℃; however, no significant effect of duration was observed at 7 or 14℃. At 14℃, trypsin activity significantly decreased over 10 and 20 days, then increased; amylase and trypsin activity significantly decreased after 40 days at 28℃. However, no significant effect of duration was found on amylase, pepsin or trypsin activities in the other temperature treatment groups. At 28℃, lipase activity peaked in 20 days and then markedly decreased to a minimum at the end of the experiment. On the other hand, pepsin activity at 28℃ continuously increased over the whole experimental period. Principle component analysis showed that sea cucumbers on day 40 in the 21℃ group and in the previous 20 days in the 28℃ group were in the prophase of aestivation. At 28℃, sea cucumbers aestivated at 30-40 days after the start of the experiment. It is concluded that the effect of temperature on the digestion ofA. japonicus is comparatively weak within a specific range of water temperatures and aestivation behavior is accompanied by significant changes in RGM and digestive enzyme activities.展开更多
AIM To assess the accuracy of Look-Locker on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(GdEOB-DTPA)-enhanced magnetic resonance imaging(MRI) for staging liver fibrosis in chronic hepatitis B/C(CHB/C)....AIM To assess the accuracy of Look-Locker on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(GdEOB-DTPA)-enhanced magnetic resonance imaging(MRI) for staging liver fibrosis in chronic hepatitis B/C(CHB/C).METHODS We prospectively included 109 patients with CHB or CHC who underwent a 3.0-Tesla MRI examination, including T1-weighted and Look-Locker sequences for T1 mapping. Hepatocyte fractions(He F) and relaxation time reduction rate(RE) were measured for staging liver fibrosis. A receiver operating characteristic analysis using the area under the receiver operating characteristic curve(AUC) was used to compare thediagnostic performance in predicting liver fibrosis between He F and RE.RESULTS A total of 73 patients had both pathological results and MRI information. The number of patients in each fibrosis stage was evaluated semiquantitatively according to the METAVIR scoring system: F0, n = 23(31.5%); F1, n = 19(26.0%); F2, n = 13(17.8%); F3, n = 6(8.2%), and F4, n = 12(16.4%). He F by EOB enhancement imaging was significantly correlated with fibrosis stage(r =-0.808, P < 0.05). AUC values for diagnosis of any(≥ F1), significant(≥ F2) or advanced(≥ F3) fibrosis, and cirrhosis(F4) using He F were 0.837(0.733-0.913), 0.890(0.795-0.951), 0.957(0.881-0.990), and 0.957(0.882-0.991), respectively. He F measurement was more accurate than use of RE in establishing liver fibrosis staging, suggesting that calculation of He F is a superior noninvasive liver fibrosis staging method.CONCLUSION A T1 mapping-based He F method is an efficient diagnostic tool for the staging of liver fibrosis.展开更多
The effect of processing parameters such as hot rolling and heat treatment on microstructure and mechanical properties was investigated for a new 0.27mass% C and Ni, Mo-free low alloy martensitic abrasion resistant st...The effect of processing parameters such as hot rolling and heat treatment on microstructure and mechanical properties was investigated for a new 0.27mass% C and Ni, Mo-free low alloy martensitic abrasion resistant steel. The three-body impact abrasive wear behavior was also analyzed. The results showed that two-step controlled rolling besides quenching at 880 ℃ and tempering at 170 ℃ could result in optimal mechanical property., the Brinell hardness, tensile strength, elongation and --40 ℃ impact toughness were 531, 1530 MPa, 11.8% and 58 J, re- spectively. The microstructure was of fine lath martensite with little retained austenite. Three-body impact abrasive wear results showed that wear mechanism was mainly of plastic deformation fatigue when the impact energy was 2 J, and the relative wear resistance was 1.04 times higher than that of the same grade compared steel under the same working condition. The optimal hardness and toughness match was the main reason of higher wear resistance.展开更多
Multi-label learning deals with problems where each example is represented by a single instance while being associated with multiple class labels simultaneously. Binary relevance is arguably the most intuitive solutio...Multi-label learning deals with problems where each example is represented by a single instance while being associated with multiple class labels simultaneously. Binary relevance is arguably the most intuitive solution for learning from multi-label examples. It works by decomposing the multi-label learning task into a number of independent binary learning tasks （one per class label）. In view of its potential weakness in ignoring correlations between labels, many correlation-enabling extensions to binary relevance have been proposed in the past decade. In this paper, we aim to review the state of the art of binary relevance from three perspectives. First, basic settings for multi-label learning and binary relevance solutions are briefly summarized. Second, representative strategies to provide binary relevance with label correlation exploitation abilities are discussed. Third, some of our recent studies on binary relevance aimed at issues other than label correlation exploitation are introduced. As a conclusion, we provide suggestions on future research directions.展开更多
An intensive field campaign was conducted in Chongqing during the summer of 2015 to explore the formation mechanisms of ozone pollution. The sources of ozone, the local production rates, and the controlling factors, a...An intensive field campaign was conducted in Chongqing during the summer of 2015 to explore the formation mechanisms of ozone pollution. The sources of ozone, the local production rates, and the controlling factors, as well as key species of volatile organic compounds(VOCs), were quantified by integrating a local ozone budget analysis, calculations of the relative incremental reactivity, and an empirical kinetic model approach. It was found that the potential for rapid local ozone formation exists in Chongqing. During ozone pollution episodes, the ozone production rates were found to be high at the upwind station Nan Quan, the urban station Chao Zhan, and the downwind station Jin-Yun Shan. The average local ozone production rate was 30×10^(-9) V/V h^(-1) and the daily integration of the produced ozone was greater than 180×10^(-9) V/V. High ozone concentrations were associated with urban and downwind air masses. At most sites, the local ozone production was VOC-limited and the key species were aromatics and alkene, which originated mainly from vehicles and solvent usage. In addition, the air masses at the northwestern rural sites were NO_x-limited and the local ozone production rates were significantly higher during the pollution episodes due to the increased NOx concentrations. In summary, the ozone abatement strategies of Chongqing should be focused on the mitigation of VOCs. Nevertheless, a reduction in NO_x is also beneficial for reducing the regional ozone peak values in Chongqing and the surrounding areas.展开更多
BACKGROUND: There is a controversy over the degree of liver and biliary injury caused by the period of secondary warm ischemia. A liver autotransplantation model was adopted because it excludes the effects of infectio...BACKGROUND: There is a controversy over the degree of liver and biliary injury caused by the period of secondary warm ischemia. A liver autotransplantation model was adopted because it excludes the effects of infection and immunological rejection on bile duct injury. This study was undertaken to assess biliary tract injury caused by relative warm ischemia (secondary warm ischemia time in the biliary tract) and reperfusion. METHODS: One hundred and two rats were randomly divided into 5 groups: group I (control); groups 11 to V, relative warm ischemia times of 0 minute, 30 minutes, I hour and 2 hours. In addition to the levels of serum alkaline phosphatase, and total bilirubin, pathomorphology assessment and TUNEL assay were performed to evaluate biliary tract damage. RESULTS: Under the conditions that there were no significant differences in warm ischemia time, cold perfusion time and anhepatic phase, group comparisons showed statistically significant differences. The least injury occurred in group H (portal vein and hepatic artery reperfused simultaneously) but the most severe injury occurred in group V (biliary tract relative warm ischemia time 2 hours). CONCLUSIONS: Relative warm ischemia is one of the factors that result in bile duct injury, and the relationship between relative warm ischemia time the bile injury degree is time-dependent. Simultaneous arterial and portal reperfusion is the best choice to avoid the bile duct injury caused by relative warm ischemia. (Hepatobiliary Pancreat Dis Int 2009; 8: 247-254)展开更多
To better understand the potential causes of visibility impairment in autumn and winter in Chengdu,relative humidity(RH),visibility,the concentrations of PM2.5 and its chemical components were on-line measured continu...To better understand the potential causes of visibility impairment in autumn and winter in Chengdu,relative humidity(RH),visibility,the concentrations of PM2.5 and its chemical components were on-line measured continuously in Chengdu from Nov.2016 to Jan.2017.Six obvious haze episodes occurred in Chengdu,with the total time of haze episodes accounted for more than 90%of the total observation period,and higher NO2 concentrations and RH were related to the high particle concentrations in haze episodes.The visibility decreased in a non-linear tendency under different RH conditions with the increase of PM2.5 concentrations,which was more sensitive to RH under lower PM2.5 concentrations.The threshold concentration of PM2.5 got more smaller with the increase of RH.During the entire observation period,organic matter(OM)was the largest contributor(31.12%to extinction coefficient(bext)),followed by NH4NO3 and(NH4)2SO4 with 28.03%and 23.01%,respectively.However,with the visibility impairment from Type I(visibility>10 km)to Type IV(visibility≤2 km),the contribution of OM to bextdecreased from 38.12%to 26.77%,while the contribution of NH4NO3 and(NH4)2SO4 to bextincreased from 19.09%and 20.20%to 34.29%and 24.35%,respectively,and NH4NO3 became the largest contributor to bextat Type IV.The results showed that OM and NH4NO3 were the key components of PM2.5 for visibility impairment in Chengdu,indicating that the control of precursors emissions of carbonaceous species and NH4NO3 could effectively improve the visibility in Chengdu.展开更多
In the Late Cambrian, the North China Platform was a typical carbonate ramp platform. The Upper Cambrian of the northern part of the North China Platform is famous for the development of bioherm limestones and storm c...In the Late Cambrian, the North China Platform was a typical carbonate ramp platform. The Upper Cambrian of the northern part of the North China Platform is famous for the development of bioherm limestones and storm calcirudites and can be divided from bottom to top into the Gushan, Changshan and Fengshan formations. In this set of strata, the deep-ramp mudstone and marls and the shallow-ramp packstones and grainstones constitute many carbonate meter-scale cycles of subtidal type. More tidal-flat dolomites are developed in the Upper Cambrian of the southern margin of the North China platform, in which limestone and dolomite beds also constitute many carbonate meter-scale cycles of the peritidal type. These cycles are marked by a variety of litho-facies successions. There are regularly vertical stacking patterns of meter-scale cycles in long-term third-order sequences, which is the key to discerning such sequences. Third- order sequence is marked by a particular sedimentary-facies succession that is the result of the environment-changing process of deepening and shoaling, which is genetically related to third-order sea level changes. Furthermore, four third- order sequences can be grouped in the Upper Cambrian of the North China Platform. The main features of these four third -order sequences in the northern part of the platform can be summarized as follows: firstly, sequence-boundaries are characterized by drowning unconformities; secondly, the sedimentary-facies succession is generally constituted by one from deep-ramp facies to shallow-ramp facies; thirdly, a succession of “CS (?)+HST” (i.e., “condensed section and high- stand system”) forms these four third-order sequences. The chief features for the third-order sequences in the southern part of the North China Platform comprises: more dolomites are developed in the HSTs of third-order sequences and also developed more carbonate meter-scale cycles of peritidal types; the sedimentary-facies succession of the third-order sequences is marked by “shallow展开更多
Based on an integrated analysis of high-resolution 2D/3D seismic data and drilling results, this study analyzes the tectonic- sedimentary evolution of the Qiongdongnan Basin （QDNB） since the late Miocene, and discus...Based on an integrated analysis of high-resolution 2D/3D seismic data and drilling results, this study analyzes the tectonic- sedimentary evolution of the Qiongdongnan Basin （QDNB） since the late Miocene, and discusses the controlling factors on the formation and development of the Central Canyon System （CCS）. The sediment failures caused by the relative sea level falling might have discharged deposits from the slope to the canyon. The two suits of the infillings, i.e., turbidites and mass transport complex （MTC）, were derived from the northwestern source and northern source, respectively. The sediment supplies, which differ significantly among different areas, might have led to the variations observed in the internal architectures. Tectonic transformation around 11.6 Ma had provided the tectonic setting for the CCS and formed an axial sub-basin in the central part of the Changchang Depression, which could be called the rudiment of the CCS. The tectonic activity of the Red River Fault （RRF） at about 5.7 Ma might have strengthened the hydrodynamics of the deposits at the junction of the Yinggehal Basin （YGHB） and the QDNB to trigger a high-energy turbidity current. The MTC from the northern continental slope system might have been constrained by the Southern Uplift, functioning as a barrier for the infillings of the CCS. Thanks to a sufficient sediment supply during the Holocene period and the paleo-seafloor morphology, the relief of modern central canyon with the starving landform in the eastern Changchang Depression might have been accentuated by deposition of sediments and vertical growth along the canyon flanks, where collapse deposits were widely developed. Corresponding to the segmentation of the CCS, the forming mechanisms of the canyon between the three segments would be different. The turbidite channel in the head area had likely been triggered by the abundant sediment supply from the northwestern source together with the fault activity at about 5.7 Ma of the RRF. The formation and evo展开更多
基金supported by National Key Basic Research Program of China(Grant Nos.2012CB417205 and 2013CB430202)the National Natural Science Foundation of China(Grant No.41130960)National Science and Technology Support Program of China(Grant No.2009BAC51B02)
文摘Our analysis of fog and haze observations from the surface weather stations in China in recent 50 years （from 196l to 2011） shows that the number of fog days has experienced two-stage variations, with an increasing trend before 1980 and a decreasing trend after 1990. Especially, an obvious decreasing trend after 1990 can be clearly seen, which is consistent with the decreas- ing trend of the surface relative humidity. However, the number of haze days has demonstrated an increasing trend. As such, the role of reduction of atmospheric relative humidity in the transition process from fog into haze has been further investigated. It is estimated that the mean relative humidity of haze days is about 69%, lower than previously estimated, which implies that it is more difficult for the haze particles to transform into fog drops. This is possibly one of the major environmental factors leading to the reduction of number of fog days. The threshold of the relative humidity for transition from fog into haze is about 82%, also lower than previously estimated. Thus, the reduction of the surface relative humidity in China mainly due to the in- crease of the surface temperature and the saturation specific humidity may exert an obvious impact on the environmental con- ditions for the formations of fog and haze. In addition, our investigation of the relationship between haze and visibility reveals that with the increase of haze days, the visibility has declined markedly. Since 1961, the mean visibility has dropped from 4-10 to 2-4 kin, about a half of the previous horizontal distance of visibility.
基金This study was funded by Ministry of Health of Science and Technology (2001 DEA 30035,2002D2A40022,2003DIA6N008), China.
文摘Objective To estimate the relative risks of dyslipidemia, hypertension, diabetes mellitus, and metabolic syndromes among overweight and obese Chinese children compared with their normal weight counterparts. Methods Overweight and obesity were defined by age- and sex-specific BMI classification reference for Chinese children and adolescents. Pediatric metabolic syndrome （MetS） and each risk factor for MetS were defined using the criteria for US adolescents. Definition of hyper-TC, LDL, and dyslipidemia for adults was applied as well. General linear model factor analysis and chi-square test were used to compare the difference in metabolic indicators among normal weight, overweight, and obese groups. Multiple logistic regression analysis was performed to estimate the odds ratio of metabolic abnormalities between obesity, overweight, and normal weight children, after adjustment for living area, family economic level, age, sex, and daily exercise time and TV watching time, as well as different dietary indices in the model. Results Significant increases in blood lipids, glucose, and blood pressure were found among overweight and obese children as compared with their counterparts with normal weight. By applying WGOC-recommended BMI classification, the risks for hypertriglyceridemia, low HDL and dyslipidemia among overweight children were 1.9, 1.4, and 1.5 times, and was 3.3, 1.5, and 1.8 times among obese groups compared to their counterparts with normal weight after adjustment for age, sex, region, socioeconomic status, physical activity, and dietary intakes. The overweight and obese children （15-17.9 years） had a high-risk of developing hypertension, which was 2.3 and 2.9 times higher than their counterparts with normal weight. Above 90% obese adolescents had abdominal obesity, while less than 1% normal weight ones had abdominal obesity. No obese adolescents were free from any risk factors for MetS, while 36.9% of normal weight adolescents were from the risk factors. 83.3% obese boys and all obese girls had me
基金support from the National Natural Science Foundation of China (Grant No 40675072)National Basic Research Program of China (Grant No 2002CB410801)
文摘An intensive field campaign including measurements from the environmental monitoring network and from two super sites took place in the Pearl River Delta region in summer 2006.Using routinely measured O3 and NOx concentrations,the spatial and temporal variation of O3 and of the total oxidant concentrations was characterized.According to the spatial variability of NO2/NO,the two super sites were found to be representative of polluted urban and downwind suburban conditions.In addition,both sites were located in high O3 regions.In-depth diagnostic of photochemical ozone production processes and their key controlling factors are achieved with an observation-based model(OBM) to gain regional perspectives.Budget analysis and sensitivity model runs show that aldehyde and HONO chemistry had significant impacts on local photochemical ozone production rates.The analysis of calculated Relative Incremental Reactivities shows that photochemical ozone production rates are mainly sensitive to anthropogenic hydrocarbons(HCs) in the polluted urban areas.In the suburban areas,sensitivity to nitrogen oxide(NO) concentrations dominated.Key anthropogenic HCs in both areas are alkenes and aromatics.Significant differences of ozone production efficiencies are identified between the urban and suburban regions,consistent with the OBM diagnosed results.
基金Under the auspices of Key Program of National Key Technology R & D Program of China (No. 2007BAB28B01)
文摘Drought is one of the major natural disasters causing huge agricultural losses annually. Regional agricultural drought risk assessment has great significance for reducing regional disaster and agricultural drought losses. Based on the fuzzy characteristics of agricultural drought risk, variable fuzzy sets model was used for comprehensively assessing agricultural drought risk of Liaoning Province in China. A multi-layers and multi-indices assessment model was estab-lished according to variable fuzzy sets theory, and agricultural drought risk of all 14 prefecture-level cities was respec-tively estimated in terms of dangerousness, vulnerability, exposure and drought-resistibility. By calculating the combi-nation weights of four drought risk factors, agricultural drought risk grade of each city was obtained. Based on the as-sessment results, the spatial distribution maps of agricultural drought risk were drawn. The results shows that eastern cities have lower drought dangerousness than western cities in Liaoning Province totally. Most cities are located in low drought vulnerability region and high drought exposure region. Because of frequent and severe drought since 2000, most cities are located in lower drought-resistibility region. Comprehensive agricultural drought risk presents apparent spatial characteristics, escalating from the east to the west. Drought dangerousness is the most important factor influencing comprehensive agricultural drought risk. Through the spatial distribution maps of drought risk, decision makers could find out drought situation and make decisions on drought resistance conveniently.
基金Supported by the Science Fund for Creative Research Groups (No.40821004)National Natural Science Foundation of China (No.40576073)+1 种基金Breeding Project of Shandong Province (China),National Key Technology Research and Development Program of China (No. 2006BAD09A02)the National High Technology Research and Development Program of China (863 Program) (No.2006AA100304 /2006AA10A411)
文摘The effect of water temperature on gut mass and digestive enzyme activity in sea cucumber Apostichopusjaponicus, including relative gut mass （RGM）, amylase, lipase, pepsin and trypsin activities were studied at temperatures of 7, 14, 21, and 28℃ over a period of 40 days. Results show that RGM significantly decreased after 40 days at 21 ℃ and markedly decreased over the whole experiment period at 28℃; however, no significant effect of duration was observed at 7 or 14℃. At 14℃, trypsin activity significantly decreased over 10 and 20 days, then increased; amylase and trypsin activity significantly decreased after 40 days at 28℃. However, no significant effect of duration was found on amylase, pepsin or trypsin activities in the other temperature treatment groups. At 28℃, lipase activity peaked in 20 days and then markedly decreased to a minimum at the end of the experiment. On the other hand, pepsin activity at 28℃ continuously increased over the whole experimental period. Principle component analysis showed that sea cucumbers on day 40 in the 21℃ group and in the previous 20 days in the 28℃ group were in the prophase of aestivation. At 28℃, sea cucumbers aestivated at 30-40 days after the start of the experiment. It is concluded that the effect of temperature on the digestion ofA. japonicus is comparatively weak within a specific range of water temperatures and aestivation behavior is accompanied by significant changes in RGM and digestive enzyme activities.
基金Supported by National Natural Science Foundation of China,No.81771893,No.81771802,No.81471718 and No.81401376Outstanding youth Foundation of China Medical University,No.yq20160005
文摘AIM To assess the accuracy of Look-Locker on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(GdEOB-DTPA)-enhanced magnetic resonance imaging(MRI) for staging liver fibrosis in chronic hepatitis B/C(CHB/C).METHODS We prospectively included 109 patients with CHB or CHC who underwent a 3.0-Tesla MRI examination, including T1-weighted and Look-Locker sequences for T1 mapping. Hepatocyte fractions(He F) and relaxation time reduction rate(RE) were measured for staging liver fibrosis. A receiver operating characteristic analysis using the area under the receiver operating characteristic curve(AUC) was used to compare thediagnostic performance in predicting liver fibrosis between He F and RE.RESULTS A total of 73 patients had both pathological results and MRI information. The number of patients in each fibrosis stage was evaluated semiquantitatively according to the METAVIR scoring system: F0, n = 23(31.5%); F1, n = 19(26.0%); F2, n = 13(17.8%); F3, n = 6(8.2%), and F4, n = 12(16.4%). He F by EOB enhancement imaging was significantly correlated with fibrosis stage(r =-0.808, P < 0.05). AUC values for diagnosis of any(≥ F1), significant(≥ F2) or advanced(≥ F3) fibrosis, and cirrhosis(F4) using He F were 0.837(0.733-0.913), 0.890(0.795-0.951), 0.957(0.881-0.990), and 0.957(0.882-0.991), respectively. He F measurement was more accurate than use of RE in establishing liver fibrosis staging, suggesting that calculation of He F is a superior noninvasive liver fibrosis staging method.CONCLUSION A T1 mapping-based He F method is an efficient diagnostic tool for the staging of liver fibrosis.
基金Item Sponsored by National Basic Research Program of China(2010CB630801)
文摘The effect of processing parameters such as hot rolling and heat treatment on microstructure and mechanical properties was investigated for a new 0.27mass% C and Ni, Mo-free low alloy martensitic abrasion resistant steel. The three-body impact abrasive wear behavior was also analyzed. The results showed that two-step controlled rolling besides quenching at 880 ℃ and tempering at 170 ℃ could result in optimal mechanical property., the Brinell hardness, tensile strength, elongation and --40 ℃ impact toughness were 531, 1530 MPa, 11.8% and 58 J, re- spectively. The microstructure was of fine lath martensite with little retained austenite. Three-body impact abrasive wear results showed that wear mechanism was mainly of plastic deformation fatigue when the impact energy was 2 J, and the relative wear resistance was 1.04 times higher than that of the same grade compared steel under the same working condition. The optimal hardness and toughness match was the main reason of higher wear resistance.
基金Acknowledgements The authors would like to thank the associate editor and anonymous reviewers for their helpful comments and suggestions. This work was supported by the National Natural Science Foundation of China （Grant Nos. 61573104, 61622203）, the Natural Science Foundation of Jiangsu Province （BK20141340）, the Fundamental Research Funds for the Central Universities （2242017K40140）, and partially supported by the Collaborative Innovation Center of Novel Software Technology and Industrialization.
文摘Multi-label learning deals with problems where each example is represented by a single instance while being associated with multiple class labels simultaneously. Binary relevance is arguably the most intuitive solution for learning from multi-label examples. It works by decomposing the multi-label learning task into a number of independent binary learning tasks （one per class label）. In view of its potential weakness in ignoring correlations between labels, many correlation-enabling extensions to binary relevance have been proposed in the past decade. In this paper, we aim to review the state of the art of binary relevance from three perspectives. First, basic settings for multi-label learning and binary relevance solutions are briefly summarized. Second, representative strategies to provide binary relevance with label correlation exploitation abilities are discussed. Third, some of our recent studies on binary relevance aimed at issues other than label correlation exploitation are introduced. As a conclusion, we provide suggestions on future research directions.
基金supportted by the Environmental Public Welfare Industry in China (Grant No. 201509001)the National Science and Technology Supporting Plan (Grant No. 2014BAC21B01)the Chongqing Project of the Ozone Source Appointment
文摘An intensive field campaign was conducted in Chongqing during the summer of 2015 to explore the formation mechanisms of ozone pollution. The sources of ozone, the local production rates, and the controlling factors, as well as key species of volatile organic compounds(VOCs), were quantified by integrating a local ozone budget analysis, calculations of the relative incremental reactivity, and an empirical kinetic model approach. It was found that the potential for rapid local ozone formation exists in Chongqing. During ozone pollution episodes, the ozone production rates were found to be high at the upwind station Nan Quan, the urban station Chao Zhan, and the downwind station Jin-Yun Shan. The average local ozone production rate was 30×10^(-9) V/V h^(-1) and the daily integration of the produced ozone was greater than 180×10^(-9) V/V. High ozone concentrations were associated with urban and downwind air masses. At most sites, the local ozone production was VOC-limited and the key species were aromatics and alkene, which originated mainly from vehicles and solvent usage. In addition, the air masses at the northwestern rural sites were NO_x-limited and the local ozone production rates were significantly higher during the pollution episodes due to the increased NOx concentrations. In summary, the ozone abatement strategies of Chongqing should be focused on the mitigation of VOCs. Nevertheless, a reduction in NO_x is also beneficial for reducing the regional ozone peak values in Chongqing and the surrounding areas.
文摘BACKGROUND: There is a controversy over the degree of liver and biliary injury caused by the period of secondary warm ischemia. A liver autotransplantation model was adopted because it excludes the effects of infection and immunological rejection on bile duct injury. This study was undertaken to assess biliary tract injury caused by relative warm ischemia (secondary warm ischemia time in the biliary tract) and reperfusion. METHODS: One hundred and two rats were randomly divided into 5 groups: group I (control); groups 11 to V, relative warm ischemia times of 0 minute, 30 minutes, I hour and 2 hours. In addition to the levels of serum alkaline phosphatase, and total bilirubin, pathomorphology assessment and TUNEL assay were performed to evaluate biliary tract damage. RESULTS: Under the conditions that there were no significant differences in warm ischemia time, cold perfusion time and anhepatic phase, group comparisons showed statistically significant differences. The least injury occurred in group H (portal vein and hepatic artery reperfused simultaneously) but the most severe injury occurred in group V (biliary tract relative warm ischemia time 2 hours). CONCLUSIONS: Relative warm ischemia is one of the factors that result in bile duct injury, and the relationship between relative warm ischemia time the bile injury degree is time-dependent. Simultaneous arterial and portal reperfusion is the best choice to avoid the bile duct injury caused by relative warm ischemia. (Hepatobiliary Pancreat Dis Int 2009; 8: 247-254)
基金supported by Sichuan Science and Technology Program (Nos. 2018SZ0316, 2018SZDZX0023)the Research on Forecasting Technology of Heavy Pollution Weather
文摘To better understand the potential causes of visibility impairment in autumn and winter in Chengdu,relative humidity(RH),visibility,the concentrations of PM2.5 and its chemical components were on-line measured continuously in Chengdu from Nov.2016 to Jan.2017.Six obvious haze episodes occurred in Chengdu,with the total time of haze episodes accounted for more than 90%of the total observation period,and higher NO2 concentrations and RH were related to the high particle concentrations in haze episodes.The visibility decreased in a non-linear tendency under different RH conditions with the increase of PM2.5 concentrations,which was more sensitive to RH under lower PM2.5 concentrations.The threshold concentration of PM2.5 got more smaller with the increase of RH.During the entire observation period,organic matter(OM)was the largest contributor(31.12%to extinction coefficient(bext)),followed by NH4NO3 and(NH4)2SO4 with 28.03%and 23.01%,respectively.However,with the visibility impairment from Type I(visibility>10 km)to Type IV(visibility≤2 km),the contribution of OM to bextdecreased from 38.12%to 26.77%,while the contribution of NH4NO3 and(NH4)2SO4 to bextincreased from 19.09%and 20.20%to 34.29%and 24.35%,respectively,and NH4NO3 became the largest contributor to bextat Type IV.The results showed that OM and NH4NO3 were the key components of PM2.5 for visibility impairment in Chengdu,indicating that the control of precursors emissions of carbonaceous species and NH4NO3 could effectively improve the visibility in Chengdu.
文摘In the Late Cambrian, the North China Platform was a typical carbonate ramp platform. The Upper Cambrian of the northern part of the North China Platform is famous for the development of bioherm limestones and storm calcirudites and can be divided from bottom to top into the Gushan, Changshan and Fengshan formations. In this set of strata, the deep-ramp mudstone and marls and the shallow-ramp packstones and grainstones constitute many carbonate meter-scale cycles of subtidal type. More tidal-flat dolomites are developed in the Upper Cambrian of the southern margin of the North China platform, in which limestone and dolomite beds also constitute many carbonate meter-scale cycles of the peritidal type. These cycles are marked by a variety of litho-facies successions. There are regularly vertical stacking patterns of meter-scale cycles in long-term third-order sequences, which is the key to discerning such sequences. Third- order sequence is marked by a particular sedimentary-facies succession that is the result of the environment-changing process of deepening and shoaling, which is genetically related to third-order sea level changes. Furthermore, four third- order sequences can be grouped in the Upper Cambrian of the North China Platform. The main features of these four third -order sequences in the northern part of the platform can be summarized as follows: firstly, sequence-boundaries are characterized by drowning unconformities; secondly, the sedimentary-facies succession is generally constituted by one from deep-ramp facies to shallow-ramp facies; thirdly, a succession of “CS (?)+HST” (i.e., “condensed section and high- stand system”) forms these four third-order sequences. The chief features for the third-order sequences in the southern part of the North China Platform comprises: more dolomites are developed in the HSTs of third-order sequences and also developed more carbonate meter-scale cycles of peritidal types; the sedimentary-facies succession of the third-order sequences is marked by “shallow
基金supported by the Major Research Plan of the National Natural Science Foundation of China(Grant No.91028009)the Young Scientists Fund of the National Natural Science Foundation of China(Grant No.41002031)the Foundation of State Key Laboratory of Petroleum Resource and Prospecting,China University of Petroleum(Grant No.PRP/open-1205)
文摘Based on an integrated analysis of high-resolution 2D/3D seismic data and drilling results, this study analyzes the tectonic- sedimentary evolution of the Qiongdongnan Basin （QDNB） since the late Miocene, and discusses the controlling factors on the formation and development of the Central Canyon System （CCS）. The sediment failures caused by the relative sea level falling might have discharged deposits from the slope to the canyon. The two suits of the infillings, i.e., turbidites and mass transport complex （MTC）, were derived from the northwestern source and northern source, respectively. The sediment supplies, which differ significantly among different areas, might have led to the variations observed in the internal architectures. Tectonic transformation around 11.6 Ma had provided the tectonic setting for the CCS and formed an axial sub-basin in the central part of the Changchang Depression, which could be called the rudiment of the CCS. The tectonic activity of the Red River Fault （RRF） at about 5.7 Ma might have strengthened the hydrodynamics of the deposits at the junction of the Yinggehal Basin （YGHB） and the QDNB to trigger a high-energy turbidity current. The MTC from the northern continental slope system might have been constrained by the Southern Uplift, functioning as a barrier for the infillings of the CCS. Thanks to a sufficient sediment supply during the Holocene period and the paleo-seafloor morphology, the relief of modern central canyon with the starving landform in the eastern Changchang Depression might have been accentuated by deposition of sediments and vertical growth along the canyon flanks, where collapse deposits were widely developed. Corresponding to the segmentation of the CCS, the forming mechanisms of the canyon between the three segments would be different. The turbidite channel in the head area had likely been triggered by the abundant sediment supply from the northwestern source together with the fault activity at about 5.7 Ma of the RRF. The formation and evo
