Background Regional ejection fraction （EFR） measured by real-time three-dimensional echocardiography （RT-3DE） provides a novel method for quantifying left-ventricular （LV） regional systolic function. We aimed to...Background Regional ejection fraction （EFR） measured by real-time three-dimensional echocardiography （RT-3DE） provides a novel method for quantifying left-ventricular （LV） regional systolic function. We aimed to explore the diagnostic value of regional ejection fraction （EFR） derived from RT-3DE in detecting LV aneurysms in patients with myocardial infarction. Methods Thirty-eight patients with myocardial infarction were prospectively enrolled and underwent electrocardiography （ECG）, two-dimensional echocardiography （2-DE）, RT-3DE and left ventriculography （LVG）. Subjects with a negative EFR in at least one segment on RT-3DE were considered as having a ventricular aneurysm. We compared the sensitivity, specificity, Youden＇s index, and positive and negative predictive values of ECG, 2-DE and RT-3DE in determining LV aneurysm with detection by LVG. Results On LVG an LV aneurysm was diagnosed in 16 （42.1%） patients. The sensitivity and specificity were 62.5% and 86.4% for ECG, 81.2% and 95.4% for 2-DE, and 100.0% and 90.9% for RT-3DE in diagnosing LV aneurysm. Youden＇s indexes for ECG, 2-DE and RT-3DE were 0.49, 0.77 and 0.91, respectively. Positive and negative predictive values were 76.9% and 76.0% for ECG, 92.9% and 87.5% for 2-DE, and 88.9% and 100.0% for RT-3DE. Conclusions RT-3DE-derived EFR provides a novel, reliable index in the diagnosis of LV aneurysm and has excellent sensitivity and specificity.展开更多
本研究运用门控平衡法心血池显像(MGBP)观察了心肌梗塞组(MI)30例,原发性高血压病组(EH)20例及对照组(N)15例三组的左室局部射血分数(EF_1—EF_5)及局部轴缩短率(RS_1—RS_5)的变化,发现 MI 组的局部 EF 及 RS的变化与梗塞部位相符(40/4...本研究运用门控平衡法心血池显像(MGBP)观察了心肌梗塞组(MI)30例,原发性高血压病组(EH)20例及对照组(N)15例三组的左室局部射血分数(EF_1—EF_5)及局部轴缩短率(RS_1—RS_5)的变化,发现 MI 组的局部 EF 及 RS的变化与梗塞部位相符(40/46、85%),与 N 组比较各部位EF与RS均有显著性差异(P<0.05—0.001).EH组与N组比较除EF_4、RS_4的差异有显著性意义(P<0.05)以外,其余EF、RS两组的差异无显著性意义(P>0.05),提示左室局部EF及RS改变对于判断MI及EH的病变部位和病情变化有确定的应用价值.三组各部位EF与RS均呈正相关关系(P<0.05—0.001).展开更多
文摘Background Regional ejection fraction （EFR） measured by real-time three-dimensional echocardiography （RT-3DE） provides a novel method for quantifying left-ventricular （LV） regional systolic function. We aimed to explore the diagnostic value of regional ejection fraction （EFR） derived from RT-3DE in detecting LV aneurysms in patients with myocardial infarction. Methods Thirty-eight patients with myocardial infarction were prospectively enrolled and underwent electrocardiography （ECG）, two-dimensional echocardiography （2-DE）, RT-3DE and left ventriculography （LVG）. Subjects with a negative EFR in at least one segment on RT-3DE were considered as having a ventricular aneurysm. We compared the sensitivity, specificity, Youden＇s index, and positive and negative predictive values of ECG, 2-DE and RT-3DE in determining LV aneurysm with detection by LVG. Results On LVG an LV aneurysm was diagnosed in 16 （42.1%） patients. The sensitivity and specificity were 62.5% and 86.4% for ECG, 81.2% and 95.4% for 2-DE, and 100.0% and 90.9% for RT-3DE in diagnosing LV aneurysm. Youden＇s indexes for ECG, 2-DE and RT-3DE were 0.49, 0.77 and 0.91, respectively. Positive and negative predictive values were 76.9% and 76.0% for ECG, 92.9% and 87.5% for 2-DE, and 88.9% and 100.0% for RT-3DE. Conclusions RT-3DE-derived EFR provides a novel, reliable index in the diagnosis of LV aneurysm and has excellent sensitivity and specificity.
文摘本研究运用门控平衡法心血池显像(MGBP)观察了心肌梗塞组(MI)30例,原发性高血压病组(EH)20例及对照组(N)15例三组的左室局部射血分数(EF_1—EF_5)及局部轴缩短率(RS_1—RS_5)的变化,发现 MI 组的局部 EF 及 RS的变化与梗塞部位相符(40/46、85%),与 N 组比较各部位EF与RS均有显著性差异(P<0.05—0.001).EH组与N组比较除EF_4、RS_4的差异有显著性意义(P<0.05)以外,其余EF、RS两组的差异无显著性意义(P>0.05),提示左室局部EF及RS改变对于判断MI及EH的病变部位和病情变化有确定的应用价值.三组各部位EF与RS均呈正相关关系(P<0.05—0.001).
