基金国家自然科学基金项目(51477011)北京市自然科学基金重点项目(KZ201511232035)+3 种基金北京市属高校科技创新能力提升计划项目(TJSHG201310772024)Project Supported by National Natural Science Foundation of China(51477011)Program of Beijing Natural Science Foundation(KZ201511232035)Funding Project for Science and Technology Innovation Ability Enhancement in Institutions under the Jurisdiction of Beijing Municipality(TJSHG201310772024)