Objective To investigate the role of severe acute respiratory syndrome coronavirus (SARS-CoV) in the induction of acute lung injury by promoting the synthesis of chemokine/cytokines in human endothelial cells. Methods...Objective To investigate the role of severe acute respiratory syndrome coronavirus (SARS-CoV) in the induction of acute lung injury by promoting the synthesis of chemokine/cytokines in human endothelial cells. Methods Twenty-three SARS patients were enrolled in this study, comprising 15 males and 8 females, aged 27～55 years, mean (36±6) years. They were treated at Guan-展开更多
Objective To compare the efficacy and safety of low-dose rituximab combined with different dosage of glucocorticoids for immune thrombocytopenia (ITP) .Methods Seventy-four patients (35 male,median age 34years,range 1...Objective To compare the efficacy and safety of low-dose rituximab combined with different dosage of glucocorticoids for immune thrombocytopenia (ITP) .Methods Seventy-four patients (35 male,median age 34years,range 18—70 years) including 60 newly-diagnosed,6 persistent,5 chronic and 3 refractory展开更多
Objective To explore the safety and efficacy of left atrial(LA)endocardial vagal denervation catheter ablation for treating the patients with refractory vasovagal syncope(VVS).Methods A total of 57 consecutive refract...Objective To explore the safety and efficacy of left atrial(LA)endocardial vagal denervation catheter ablation for treating the patients with refractory vasovagal syncope(VVS).Methods A total of 57 consecutive refractory VVS patients with severe symptom and positive response to head-up tilt test(HUT)were enrolled.There were 22 male at the mean age of(43±13)years.The patients who had no response or couldn’t tolerate routine treatment LA model were re-established by three-dimen-展开更多
Objective To explore the effect of L-dopa on plasma homocysteine and folic acid in patients with Parkinsons’s disease (PD). Methods Twenty eight elderly PD patients and thirty normal subjects were enrolled in this gr...Objective To explore the effect of L-dopa on plasma homocysteine and folic acid in patients with Parkinsons’s disease (PD). Methods Twenty eight elderly PD patients and thirty normal subjects were enrolled in this group. The homocysteine, cobalamin and folate were examined in normal group and in PD group before treatment and after being treated with L-dopa for six months respec-展开更多
Objective To study on the expression and clinical significance of T lymphocyte subset and NK cell activity （NKA） in patients with colorectal cancer. Methods Fifty-seven cancer patients and 33 healthy controls were e...Objective To study on the expression and clinical significance of T lymphocyte subset and NK cell activity （NKA） in patients with colorectal cancer. Methods Fifty-seven cancer patients and 33 healthy controls were enrolled in this study. T lymphocyte subset was measured by SAP technique and NKA by LDH release assay based on K<sub>562</sub> cells, which served as target cells.展开更多
Objective To investigate the association of single nucleotide polymorphisms(SNPs)of the mannan-binding lectin(MBL)gene with serum levels,development,progression and prognosis of severe lupus nephritis(LN).Methods A to...Objective To investigate the association of single nucleotide polymorphisms(SNPs)of the mannan-binding lectin(MBL)gene with serum levels,development,progression and prognosis of severe lupus nephritis(LN).Methods A total of 107 severe lupus nephritis patients were enrolled in the study from January 2003 to October2013.Integrated capillary electrophoresis was used to detect MBL gene polymorphism in peripheral展开更多
Objective To investigate the role of helper T cell(Th)1,Th17 and Th22 and their effector molecules including interferon-gamma,interleukin(IL)-17 and IL-22in active phase of chronic hepatitis B(CHB)and acuteon-chronic ...Objective To investigate the role of helper T cell(Th)1,Th17 and Th22 and their effector molecules including interferon-gamma,interleukin(IL)-17 and IL-22in active phase of chronic hepatitis B(CHB)and acuteon-chronic liver failure(ACLF).Methods Forty-five CHB patients and 38 ACLF patients at Ruijin Hospital of Shanghai Jiaotong University School of Medicine were included,and 26 healthy controls(HC)were also enrolled.Fresh heparinized peripheral blood was展开更多
Objective To investigate the concentrations of plasma Gas6 and its receptor in acute coronary syndrome patients and their dynamic changes after PCI.Methods In this case control study,we enrolled 66 ACS patients[(63.5&...Objective To investigate the concentrations of plasma Gas6 and its receptor in acute coronary syndrome patients and their dynamic changes after PCI.Methods In this case control study,we enrolled 66 ACS patients[(63.5±14.5)years age,40 males and 26 females]and 42 age and gender matched stable coronary heart disease patients展开更多
Objective To explore the efficacy of triple therapy and sequential therapy in the eradication of Helicobacter pylori(Hp) in patients receiving long-term non-steroidal antiinflammatorv drugs(NSAID) treatment. Methods P...Objective To explore the efficacy of triple therapy and sequential therapy in the eradication of Helicobacter pylori(Hp) in patients receiving long-term non-steroidal antiinflammatorv drugs(NSAID) treatment. Methods Patients receiving long-term NSAID treatment were展开更多
2005505 Clinical significance of CD<sub><</sub>sup>+</sup> CD<sub>25</sub><sup>+</sup> T cells inperipheral blood of patients in systemic lupus erythe-matosus.YANG Xuya...2005505 Clinical significance of CD<sub><</sub>sup>+</sup> CD<sub>25</sub><sup>+</sup> T cells inperipheral blood of patients in systemic lupus erythe-matosus.YANG Xuyan（杨旭燕）,et al.Dept Rheuma-tol,2nd Affili Hosp,Med School,Zhejiang Univ,Hang-zhou 310009.Chin J Intern Med 2005;44（8）:570-572.展开更多
Objective To explore the independent risk factors for the 1 year stroke event in Chinese patients with atrial fibrillation(AF)and hypertension(HT).Methods Data of AF and HT patients in the Chinese Emergency Atrial Fib...Objective To explore the independent risk factors for the 1 year stroke event in Chinese patients with atrial fibrillation(AF)and hypertension(HT).Methods Data of AF and HT patients in the Chinese Emergency Atrial Fibrillation Registry Study were retrospectively analyzed.The eligible patients were divided into the stroke展开更多
Objective To investigate the clinical characteristics of pulmonary hypertension(PH)in patients with chronic obstructive pulmonary disease(COPD)and study the related risk factors.Methods Patients with stable COPD were ...Objective To investigate the clinical characteristics of pulmonary hypertension(PH)in patients with chronic obstructive pulmonary disease(COPD)and study the related risk factors.Methods Patients with stable COPD were enrolled in this study,undergoing examinations including full pulmonary function tests(PFT)。展开更多
Objective To investigate the association between plasma total antioxidant status (TAS) and association with brachial-ankle pulsewave velocity (baPWV) in the elderly patients with essential hypertension (EH) .Methods A...Objective To investigate the association between plasma total antioxidant status (TAS) and association with brachial-ankle pulsewave velocity (baPWV) in the elderly patients with essential hypertension (EH) .Methods A total of 133 consecutive EH patients older than 60years were enrolled and another 92 elderly non-EH healthy subjects served as control.According to blood pressure level,EH patients were further classified展开更多
Objective To analyze the therapeutic effects of the standard regimen and the optimized regimen in retreatment pulmonary tuberculosis complicated with diabetesmellitus(DM).Methods In a multi-center cohort study,patient...Objective To analyze the therapeutic effects of the standard regimen and the optimized regimen in retreatment pulmonary tuberculosis complicated with diabetesmellitus(DM).Methods In a multi-center cohort study,patients with smear positive retreatment pulmonary tuberculosis(TB)with DM and those without展开更多
Objective To evaluate the effect of percutaneous coronary intervention (PCI) on left ventricular function in patients with different types of myocardial infarction and to explore the correlation factors for the left v...Objective To evaluate the effect of percutaneous coronary intervention (PCI) on left ventricular function in patients with different types of myocardial infarction and to explore the correlation factors for the left ventricular function.Methods A total of 43 patients diagnosed as acute myocardial infarction were enrolled in this study.The perfusion and delayed enhancement magnetic resonance imaging (DE-MRI) was applied to observe the fol-展开更多
Objective To assess left ventricular (LV) strain by3-dimensional speckle tracking imaging (3D-STI) in patients with coronary heart disease (CHD) .Methods All subjects underwent invasive coronary angiography.2-dimensio...Objective To assess left ventricular (LV) strain by3-dimensional speckle tracking imaging (3D-STI) in patients with coronary heart disease (CHD) .Methods All subjects underwent invasive coronary angiography.2-dimensional and 3-dimensional echocardiography were performed in 52 subjects with suspected CHD.Longitudinal strain (LS) ,circumferential strain (CS) ,radial展开更多
Objective To study the influence of donor GFR on the early renal function in recipients undergoing living donor transplantation. Methods A total of 172 living donor transplant recipients in our kidney transplantation ...Objective To study the influence of donor GFR on the early renal function in recipients undergoing living donor transplantation. Methods A total of 172 living donor transplant recipients in our kidney transplantation center from 2006 to 2011 were enrolled into this study. Among them,166 were genetically展开更多
Objective To investigate the chronic effects of intracoronary autologous bone marrow mononuclear cell (BM-MNCs) transplantation in patients with refractory heart failure (RIHF) after myocardial infarction. Methods Thi...Objective To investigate the chronic effects of intracoronary autologous bone marrow mononuclear cell (BM-MNCs) transplantation in patients with refractory heart failure (RIHF) after myocardial infarction. Methods Thirty patients with RIHF (LVEF【40%) were enrolled in this nonrandomized study, autologous BM-MNCs (5.0±0.7)×107 were transplanted with via infarct-related coronary artery in 16 patients and 14 patients展开更多
文摘Objective To investigate the role of severe acute respiratory syndrome coronavirus (SARS-CoV) in the induction of acute lung injury by promoting the synthesis of chemokine/cytokines in human endothelial cells. Methods Twenty-three SARS patients were enrolled in this study, comprising 15 males and 8 females, aged 27～55 years, mean (36±6) years. They were treated at Guan-
文摘Objective To compare the efficacy and safety of low-dose rituximab combined with different dosage of glucocorticoids for immune thrombocytopenia (ITP) .Methods Seventy-four patients (35 male,median age 34years,range 18—70 years) including 60 newly-diagnosed,6 persistent,5 chronic and 3 refractory
文摘Objective To explore the safety and efficacy of left atrial(LA)endocardial vagal denervation catheter ablation for treating the patients with refractory vasovagal syncope(VVS).Methods A total of 57 consecutive refractory VVS patients with severe symptom and positive response to head-up tilt test(HUT)were enrolled.There were 22 male at the mean age of(43±13)years.The patients who had no response or couldn’t tolerate routine treatment LA model were re-established by three-dimen-
文摘Objective To explore the effect of L-dopa on plasma homocysteine and folic acid in patients with Parkinsons’s disease (PD). Methods Twenty eight elderly PD patients and thirty normal subjects were enrolled in this group. The homocysteine, cobalamin and folate were examined in normal group and in PD group before treatment and after being treated with L-dopa for six months respec-
文摘Objective To study on the expression and clinical significance of T lymphocyte subset and NK cell activity （NKA） in patients with colorectal cancer. Methods Fifty-seven cancer patients and 33 healthy controls were enrolled in this study. T lymphocyte subset was measured by SAP technique and NKA by LDH release assay based on K<sub>562</sub> cells, which served as target cells.
文摘Objective To investigate the association of single nucleotide polymorphisms(SNPs)of the mannan-binding lectin(MBL)gene with serum levels,development,progression and prognosis of severe lupus nephritis(LN).Methods A total of 107 severe lupus nephritis patients were enrolled in the study from January 2003 to October2013.Integrated capillary electrophoresis was used to detect MBL gene polymorphism in peripheral
文摘Objective To investigate the role of helper T cell(Th)1,Th17 and Th22 and their effector molecules including interferon-gamma,interleukin(IL)-17 and IL-22in active phase of chronic hepatitis B(CHB)and acuteon-chronic liver failure(ACLF).Methods Forty-five CHB patients and 38 ACLF patients at Ruijin Hospital of Shanghai Jiaotong University School of Medicine were included,and 26 healthy controls(HC)were also enrolled.Fresh heparinized peripheral blood was
文摘Objective To investigate the concentrations of plasma Gas6 and its receptor in acute coronary syndrome patients and their dynamic changes after PCI.Methods In this case control study,we enrolled 66 ACS patients[(63.5±14.5)years age,40 males and 26 females]and 42 age and gender matched stable coronary heart disease patients
文摘Objective To explore the efficacy of triple therapy and sequential therapy in the eradication of Helicobacter pylori(Hp) in patients receiving long-term non-steroidal antiinflammatorv drugs(NSAID) treatment. Methods Patients receiving long-term NSAID treatment were
文摘Objective To explore the independent risk factors for the 1 year stroke event in Chinese patients with atrial fibrillation(AF)and hypertension(HT).Methods Data of AF and HT patients in the Chinese Emergency Atrial Fibrillation Registry Study were retrospectively analyzed.The eligible patients were divided into the stroke
文摘Objective To investigate the clinical characteristics of pulmonary hypertension(PH)in patients with chronic obstructive pulmonary disease(COPD)and study the related risk factors.Methods Patients with stable COPD were enrolled in this study,undergoing examinations including full pulmonary function tests(PFT)。
文摘Objective To investigate the association between plasma total antioxidant status (TAS) and association with brachial-ankle pulsewave velocity (baPWV) in the elderly patients with essential hypertension (EH) .Methods A total of 133 consecutive EH patients older than 60years were enrolled and another 92 elderly non-EH healthy subjects served as control.According to blood pressure level,EH patients were further classified
文摘Objective To analyze the therapeutic effects of the standard regimen and the optimized regimen in retreatment pulmonary tuberculosis complicated with diabetesmellitus(DM).Methods In a multi-center cohort study,patients with smear positive retreatment pulmonary tuberculosis(TB)with DM and those without
文摘Objective To evaluate the effect of percutaneous coronary intervention (PCI) on left ventricular function in patients with different types of myocardial infarction and to explore the correlation factors for the left ventricular function.Methods A total of 43 patients diagnosed as acute myocardial infarction were enrolled in this study.The perfusion and delayed enhancement magnetic resonance imaging (DE-MRI) was applied to observe the fol-
文摘Objective To assess left ventricular (LV) strain by3-dimensional speckle tracking imaging (3D-STI) in patients with coronary heart disease (CHD) .Methods All subjects underwent invasive coronary angiography.2-dimensional and 3-dimensional echocardiography were performed in 52 subjects with suspected CHD.Longitudinal strain (LS) ,circumferential strain (CS) ,radial
文摘Objective To study the influence of donor GFR on the early renal function in recipients undergoing living donor transplantation. Methods A total of 172 living donor transplant recipients in our kidney transplantation center from 2006 to 2011 were enrolled into this study. Among them,166 were genetically
文摘Objective To investigate the chronic effects of intracoronary autologous bone marrow mononuclear cell (BM-MNCs) transplantation in patients with refractory heart failure (RIHF) after myocardial infarction. Methods Thirty patients with RIHF (LVEF【40%) were enrolled in this nonrandomized study, autologous BM-MNCs (5.0±0.7)×107 were transplanted with via infarct-related coronary artery in 16 patients and 14 patients
