Supercritical fluid chromatography(SFC) meets with great favor due to its high efficiency, low organic solvent consumption, and the specialty for the identification of the isomeric species. This review describes the a...Supercritical fluid chromatography(SFC) meets with great favor due to its high efficiency, low organic solvent consumption, and the specialty for the identification of the isomeric species. This review describes the advances of SFC in targeted and untargeted lipid profiling. The advancement of the SFC instruments and the stationary phases are summarized. Typical applications of SFC to the targeted and untargeted lipid profiling are discussed in detail. Moreover, the perspectives of SFC in the lipid profiling are also proposed. As a useful and promising tool for investigating lipids in vitro and in vivo, SFC will predictably obtain further development.展开更多
肿瘤是最常见的危害人类健康的疾病之一,但其早期诊断困难,导致患者不能及时、恰当地接受治疗。因此,探索肿瘤早期诊断的新方法,早发现、早治疗是肿瘤治愈的关键。目前,基因表达谱技术等新型诊断方法得到越来越多的应用。本文针对发表...肿瘤是最常见的危害人类健康的疾病之一,但其早期诊断困难,导致患者不能及时、恰当地接受治疗。因此,探索肿瘤早期诊断的新方法,早发现、早治疗是肿瘤治愈的关键。目前,基因表达谱技术等新型诊断方法得到越来越多的应用。本文针对发表在《临床医师肿瘤杂志》(CA Cancer J Clin)2009年第5期上的1篇综述文章,提出虽然基因表达谱技术是一项很有前景的诊断方法,但是经济效益分析暂时不支持其在临床大范围推广,期望能够引起同行的争鸣。展开更多
基金supported by the National Natural Science Foundation of China (Grant No. 21775047)Pearl River S and T Nova Program of Guangzhou, China (Grant No. 201806010055)the Fundamental Research Funds for the Central Universities (Grant No. 2018MS55)
文摘Supercritical fluid chromatography(SFC) meets with great favor due to its high efficiency, low organic solvent consumption, and the specialty for the identification of the isomeric species. This review describes the advances of SFC in targeted and untargeted lipid profiling. The advancement of the SFC instruments and the stationary phases are summarized. Typical applications of SFC to the targeted and untargeted lipid profiling are discussed in detail. Moreover, the perspectives of SFC in the lipid profiling are also proposed. As a useful and promising tool for investigating lipids in vitro and in vivo, SFC will predictably obtain further development.
文摘肿瘤是最常见的危害人类健康的疾病之一,但其早期诊断困难,导致患者不能及时、恰当地接受治疗。因此,探索肿瘤早期诊断的新方法,早发现、早治疗是肿瘤治愈的关键。目前,基因表达谱技术等新型诊断方法得到越来越多的应用。本文针对发表在《临床医师肿瘤杂志》(CA Cancer J Clin)2009年第5期上的1篇综述文章,提出虽然基因表达谱技术是一项很有前景的诊断方法,但是经济效益分析暂时不支持其在临床大范围推广,期望能够引起同行的争鸣。
