Chronic hepatitis B virus(HBV) infection is a major cause of cirrhosis and hepatocellular carcinoma(HCC). Applying the same strategies for antiviral therapy and HCC surveillance to all chronic hepatitis B(CHB) patient...Chronic hepatitis B virus(HBV) infection is a major cause of cirrhosis and hepatocellular carcinoma(HCC). Applying the same strategies for antiviral therapy and HCC surveillance to all chronic hepatitis B(CHB) patients would be a burden worldwide. To properly manage CHB patients, it is necessary to identify and classify the risk for HCC development in such patients. Several HCC risk scores based on risk factors such as cirrhosis, age, male gender, and high viral load have been used, and have negative predictive values of ≥ 95%. Most of these have been derived from, and internally validated in, treatment-na?ve Asian CHB patients. Herein, we summarized various HCC prediction models, including IPM(Individual Prediction Model), CU-HCC(Chinese University-HCC), GAG-HCC(Guide with Age, Gender, HBV DNA, Core Promoter Mutations and Cirrhosis-HCC), NGM-HCC(NomogramHCC), REACH-B(Risk Estimation for Hepatocellular Carcinoma in Chronic Hepatitis B), and Page-B score. To develop a noninvasive test of liver fibrosis, we also introduced a new scoring system that uses liver stiffness values from transient elastography, including an LSM(Liver Stiffness Measurement)-based model, LSM-HCC, and mR EACH-B(modified REACH-B).展开更多
本文介绍了确定普通混凝土导热系数的四个理论模型,它们分别是Campbell-Allen and Thorne模型、Hamilton and Crosser模型、Kook-Han Kim模型以及朱伯芳模型。通过这几个模型计算了不同骨料体积含量及不同强度等级混凝土的导热系数,并...本文介绍了确定普通混凝土导热系数的四个理论模型,它们分别是Campbell-Allen and Thorne模型、Hamilton and Crosser模型、Kook-Han Kim模型以及朱伯芳模型。通过这几个模型计算了不同骨料体积含量及不同强度等级混凝土的导热系数,并将这些计算值与实验值比较,可以发现Kook-Han Kim模型计算值的线性拟合与实验值较为接近;虽然其它三个模型计算值的线性拟合与实验值有一定误差,但当混凝土本身的导热系数越高时,它们得到的计算值的线性拟合与实验实测值的误差越小,而且这些模型足够可以反应各个因素对混凝土导热系数的影响。展开更多
文摘Chronic hepatitis B virus(HBV) infection is a major cause of cirrhosis and hepatocellular carcinoma(HCC). Applying the same strategies for antiviral therapy and HCC surveillance to all chronic hepatitis B(CHB) patients would be a burden worldwide. To properly manage CHB patients, it is necessary to identify and classify the risk for HCC development in such patients. Several HCC risk scores based on risk factors such as cirrhosis, age, male gender, and high viral load have been used, and have negative predictive values of ≥ 95%. Most of these have been derived from, and internally validated in, treatment-na?ve Asian CHB patients. Herein, we summarized various HCC prediction models, including IPM(Individual Prediction Model), CU-HCC(Chinese University-HCC), GAG-HCC(Guide with Age, Gender, HBV DNA, Core Promoter Mutations and Cirrhosis-HCC), NGM-HCC(NomogramHCC), REACH-B(Risk Estimation for Hepatocellular Carcinoma in Chronic Hepatitis B), and Page-B score. To develop a noninvasive test of liver fibrosis, we also introduced a new scoring system that uses liver stiffness values from transient elastography, including an LSM(Liver Stiffness Measurement)-based model, LSM-HCC, and mR EACH-B(modified REACH-B).
文摘本文介绍了确定普通混凝土导热系数的四个理论模型,它们分别是Campbell-Allen and Thorne模型、Hamilton and Crosser模型、Kook-Han Kim模型以及朱伯芳模型。通过这几个模型计算了不同骨料体积含量及不同强度等级混凝土的导热系数,并将这些计算值与实验值比较,可以发现Kook-Han Kim模型计算值的线性拟合与实验值较为接近;虽然其它三个模型计算值的线性拟合与实验值有一定误差,但当混凝土本身的导热系数越高时,它们得到的计算值的线性拟合与实验实测值的误差越小,而且这些模型足够可以反应各个因素对混凝土导热系数的影响。
