The Pearl River Mouth Basin(PRMB)is one of the most petroliferous basins on the northern margin of the South China Sea.Knowledge of the thermal history of the PRMB is significant for understanding its tectonic evoluti...The Pearl River Mouth Basin(PRMB)is one of the most petroliferous basins on the northern margin of the South China Sea.Knowledge of the thermal history of the PRMB is significant for understanding its tectonic evolution and for unraveling its poorly studied source-rock maturation history.Our investigations in this study are based on apatite fission-track(AFT)thermochronology analysis of 12 cutting samples from 4 boreholes.Both AFT ages and length data suggested that the PRMB has experienced quite complicated thermal evolution.Thermal history modeling results unraveled four successive events of heating separated by three stages of cooling since the early Middle Eocene.The cooling events occurred approximately in the Late Eocene,early Oligocene,and the Late Miocene,possibly attributed to the Zhuqiong II Event,Nanhai Event,and Dongsha Event,respectively.The erosion amount during the first cooling stage is roughly estimated to be about 455-712 m,with an erosion rate of 0.08-0.12 mm/a.The second erosion-driven cooling is stronger than the first one,with an erosion amount of about 747-814 m and an erosion rate between about 0.13-0.21 mm/a.The erosion amount calculated related to the third cooling event varies from 800 m to 3419 m,which is speculative due to the possible influence of the magmatic activity.展开更多
Acupuncture can be used to treat various nervous system diseases.Here,168 vascular dementia patients were orally administered donepezil hydrochloride alone（5 mg/day,once a day for 56 days）,or combined with acupunctu...Acupuncture can be used to treat various nervous system diseases.Here,168 vascular dementia patients were orally administered donepezil hydrochloride alone（5 mg/day,once a day for 56 days）,or combined with acupuncture at Shenting（DU24）,Tianzhu（BL10）,Sishencong（Extra）,Yintang（Extra）,Renzhong（DU26）,Neiguan（PC6）,Shenmen（HT7）,Fengchi（GB20）,Wangu（GB12） and Baihui（DU20）（once a day for 56 days）.Compared with donepezil hydrochloride alone,P300 event related potential latency was shorter with an increased amplitude in patients treated with donepezil hydrochloride and acupuncture.Mini-Mental State Examination score was also higher.Moreover,these differences in P300 latency were identified within different infarcted regions in patients treated with donepezil hydrochloride and acupuncture.These findings indicate that acupuncture combined with donepezil hydrochloride noticeably improves cognitive function in patients with vascular dementia,and exerts neuroprotective effects against vascular dementia.展开更多
A moist thermodynamic advection parameter, defined as an absolute value of the dot product of hori- zontal gradients of three-dimensional potential temperature advection and general potential temperature, is introduce...A moist thermodynamic advection parameter, defined as an absolute value of the dot product of hori- zontal gradients of three-dimensional potential temperature advection and general potential temperature, is introduced to diagnose frontal heavy rainfall events in the north of China. It is shown that the parameter is closely related to observed 6-h accumulative surface rainfall and simulated cloud hydrometeors. Since the parameter is capable of describing the typical vertical structural characteristics of dynamic, thermodynamic and water vapor fields above a strong precipitation region near the front surface, it may serve as a physical tracker to detect precipitable weather systems near to a front. A tendency equation of the parameter was derived in Cartesian coordinates and calculated with the simulation output data of a heavy rainfall event. Results revealed that the advection of the parameter by the three-dimensional velocity vector, the covariance of potential temperature advection by local change of the velocity vector and general potential temperature, and the interaction between potential temperature advection and the source or sink of general potential temperature, accounted for local change in the parameter. This indicated that the parameter was determined by a combination of dynamic processes and cloud microphysical processes.展开更多
The residual consciousness of unconscious patients can be detected by studying the P300, a wave among event-related potentials. Previous studies have applied tones, the subject＇s name and other names as stimuli. Howe...The residual consciousness of unconscious patients can be detected by studying the P300, a wave among event-related potentials. Previous studies have applied tones, the subject＇s name and other names as stimuli. However, the results were not satisfactory. In this study, we changed the constituent order of subjects＇ two-character names to create derived names. The subject＇s derived names, together with tones and their own names, were used as auditory stimuli in event-related potential experiments. Healthy controls and unconscious patients were included in this study and made to listen to these auditory stimuli. In the two paradigms, a sine tone followed by the subject＇s own name and the subject＇s derived name followed by the subject＇s own name were used as standard and deviant stimuli, respectively. The results showed that all healthy controls had the P300 using both paradigms, and that the P300 in the second paradigm had a longer latency and two peaks. All minimally conscious state patients had the P300 in the first paradigm and the majority of them had the P300 in the second paradigm. Most vegetative state patients had no P300. Patients who showed the P300 in the two paradigms had more residual consciousness, and patients with the two-peak P300 had a higher probability of awakening within a short time. Our experimental findings suggest that the P300 event-related potential could reflect the conscious state of unconscious patients.展开更多
The temporal dynamics in brain evoked by the scale of visual attention with the cues of Chinese characters were studied by recording event-related potentials (ERPs). With the fixed orientation of visual attention, 14 ...The temporal dynamics in brain evoked by the scale of visual attention with the cues of Chinese characters were studied by recording event-related potentials (ERPs). With the fixed orientation of visual attention, 14 healthy young participants performed a search task in which the search array was preceded by Chinese characters cues, '大, 中, 小' (large, medium, small). 128 channels scalp ERPs were recorded to study the role of visual attention scale played in the visual spatial attention. The results showed that there was no significant difference in the ERP components evoked by the three Chinese characters cues except the in-feroposterior N2 latency. The targets evoked P2, N2 amplitudes and latency have significant differences with the different cues of large, middle and small, while P1 and N1 components had no significant difference. The results suggested that the processing of scale of visual attention was mainly concerned with P2, N2 components, while the P1, N1 components were mainly related with展开更多
Background The etiology and pathology of functional constipation （FC） is unclear.Some researches suggest that psychological factors may be related to this common problem.This study aimed to investigate the relations...Background The etiology and pathology of functional constipation （FC） is unclear.Some researches suggest that psychological factors may be related to this common problem.This study aimed to investigate the relationship between attention processing and emotional status in FC patients compared with healthy controls.Methods We investigated selective attention and emotional status in patients with FC using the counting Stroop task.Thirty-five FC patients （FCP group） and 24 healthy controls （HCs） underwent an event-related potential （ERP） study while performing the task.Response time,latency and amplitude of P300 were collected and compared between the two groups.The Hamilton Depression Rating Scale （HAMD-17）,Hamilton Anxiety Scale （HAMA）,Symptom Checklist-90 （SCL-90） and Eysenck Personality Questionnaire （EPQ） were administered prior to the counting Stroop task.Results Scores for the FCP group differed significantly from those for the HCs on the HAMD-17,HAMA,SCL-90 （Global Severity Index,Positive Symptoms Total,dimensions of somatization,obsessive-compulsive,depression,anxiety,and psychosis）,as well as extraversion and neurosis dimensions of the EPQ （P〈0.05）.There was no significant difference in response time or accuracy rate between the two groups （P〉0.05）.ERP results showed prolonged latency at F4,additionally found enhanced activation at F3,FC1 and T8,and decreased activation at sites FC6 and P7 in the patients with FC.Statistically,significant differences of P300 latency at site F4 （P 〈0.05） and P300 amplitude at F3,F4,T8,P7,FC1 and FC6 （P〈0.05） between the patients with FC and the HC were revealed.Conclusions The findings suggest that patients with FC are more susceptible to depression and anxiety,as well as somatization,obsessive-compulsive tendencies and other neurotic personality characteristics.Patients may employ psychological defense mechanisms to avoid the pain of depression and anxiety.ERP results imply there may be some brain dysfunction and a展开更多
Event-related potential studies of cognitive function in addiction behaviors have focused on the P300 event-related potential component. The current study investigated the association between P300 component and Intern...Event-related potential studies of cognitive function in addiction behaviors have focused on the P300 event-related potential component. The current study investigated the association between P300 component and Internet addiction disorder. We found that individuals with Internet addiction disorder exhibited significantly longer P300 latencies than controls （N2： P = 0.035; P3a： P = 0.031 P3b： P = 0.043） and similar P300 amplitudes compared to control participants. After 3 months of cognitive behavioral therapy, P300 latencies decreased significantly in the P3a and P3b （P3a： P = 0.045; P3b： P = 0.062）. These results suggest that deficits in cognitive function may be involved in Internet addiction disorder, and that clinical psychological treatment may be effective.展开更多
基金This study is financially supported by the National Natural Science Foundation of China(42072181).
文摘The Pearl River Mouth Basin(PRMB)is one of the most petroliferous basins on the northern margin of the South China Sea.Knowledge of the thermal history of the PRMB is significant for understanding its tectonic evolution and for unraveling its poorly studied source-rock maturation history.Our investigations in this study are based on apatite fission-track(AFT)thermochronology analysis of 12 cutting samples from 4 boreholes.Both AFT ages and length data suggested that the PRMB has experienced quite complicated thermal evolution.Thermal history modeling results unraveled four successive events of heating separated by three stages of cooling since the early Middle Eocene.The cooling events occurred approximately in the Late Eocene,early Oligocene,and the Late Miocene,possibly attributed to the Zhuqiong II Event,Nanhai Event,and Dongsha Event,respectively.The erosion amount during the first cooling stage is roughly estimated to be about 455-712 m,with an erosion rate of 0.08-0.12 mm/a.The second erosion-driven cooling is stronger than the first one,with an erosion amount of about 747-814 m and an erosion rate between about 0.13-0.21 mm/a.The erosion amount calculated related to the third cooling event varies from 800 m to 3419 m,which is speculative due to the possible influence of the magmatic activity.
文摘Acupuncture can be used to treat various nervous system diseases.Here,168 vascular dementia patients were orally administered donepezil hydrochloride alone（5 mg/day,once a day for 56 days）,or combined with acupuncture at Shenting（DU24）,Tianzhu（BL10）,Sishencong（Extra）,Yintang（Extra）,Renzhong（DU26）,Neiguan（PC6）,Shenmen（HT7）,Fengchi（GB20）,Wangu（GB12） and Baihui（DU20）（once a day for 56 days）.Compared with donepezil hydrochloride alone,P300 event related potential latency was shorter with an increased amplitude in patients treated with donepezil hydrochloride and acupuncture.Mini-Mental State Examination score was also higher.Moreover,these differences in P300 latency were identified within different infarcted regions in patients treated with donepezil hydrochloride and acupuncture.These findings indicate that acupuncture combined with donepezil hydrochloride noticeably improves cognitive function in patients with vascular dementia,and exerts neuroprotective effects against vascular dementia.
基金supported by the National Basic Research Program of China (2009CB421505)the National Natural Sciences Foundation of China (Grant Nos. 40875032 and 40875002)+1 种基金the National Science and Technology Project (GYH200706042)the Knowledge Creative Project of CAS (IAP07201)
文摘A moist thermodynamic advection parameter, defined as an absolute value of the dot product of hori- zontal gradients of three-dimensional potential temperature advection and general potential temperature, is introduced to diagnose frontal heavy rainfall events in the north of China. It is shown that the parameter is closely related to observed 6-h accumulative surface rainfall and simulated cloud hydrometeors. Since the parameter is capable of describing the typical vertical structural characteristics of dynamic, thermodynamic and water vapor fields above a strong precipitation region near the front surface, it may serve as a physical tracker to detect precipitable weather systems near to a front. A tendency equation of the parameter was derived in Cartesian coordinates and calculated with the simulation output data of a heavy rainfall event. Results revealed that the advection of the parameter by the three-dimensional velocity vector, the covariance of potential temperature advection by local change of the velocity vector and general potential temperature, and the interaction between potential temperature advection and the source or sink of general potential temperature, accounted for local change in the parameter. This indicated that the parameter was determined by a combination of dynamic processes and cloud microphysical processes.
基金supported by grants from the National Natural Science Foundation of China,No.81371194
文摘The residual consciousness of unconscious patients can be detected by studying the P300, a wave among event-related potentials. Previous studies have applied tones, the subject＇s name and other names as stimuli. However, the results were not satisfactory. In this study, we changed the constituent order of subjects＇ two-character names to create derived names. The subject＇s derived names, together with tones and their own names, were used as auditory stimuli in event-related potential experiments. Healthy controls and unconscious patients were included in this study and made to listen to these auditory stimuli. In the two paradigms, a sine tone followed by the subject＇s own name and the subject＇s derived name followed by the subject＇s own name were used as standard and deviant stimuli, respectively. The results showed that all healthy controls had the P300 using both paradigms, and that the P300 in the second paradigm had a longer latency and two peaks. All minimally conscious state patients had the P300 in the first paradigm and the majority of them had the P300 in the second paradigm. Most vegetative state patients had no P300. Patients who showed the P300 in the two paradigms had more residual consciousness, and patients with the two-peak P300 had a higher probability of awakening within a short time. Our experimental findings suggest that the P300 event-related potential could reflect the conscious state of unconscious patients.
基金This work was supported by theNational Natural Science Foundation of China (Grant No. 39970257)the Multidisciplinary Research Program of the Chinese Academy of Sciences (Grant No. KJCXl-07)by the Hundred Talents Program of the the Chinese Academy o
文摘The temporal dynamics in brain evoked by the scale of visual attention with the cues of Chinese characters were studied by recording event-related potentials (ERPs). With the fixed orientation of visual attention, 14 healthy young participants performed a search task in which the search array was preceded by Chinese characters cues, '大, 中, 小' (large, medium, small). 128 channels scalp ERPs were recorded to study the role of visual attention scale played in the visual spatial attention. The results showed that there was no significant difference in the ERP components evoked by the three Chinese characters cues except the in-feroposterior N2 latency. The targets evoked P2, N2 amplitudes and latency have significant differences with the different cues of large, middle and small, while P1 and N1 components had no significant difference. The results suggested that the processing of scale of visual attention was mainly concerned with P2, N2 components, while the P1, N1 components were mainly related with
文摘Background The etiology and pathology of functional constipation （FC） is unclear.Some researches suggest that psychological factors may be related to this common problem.This study aimed to investigate the relationship between attention processing and emotional status in FC patients compared with healthy controls.Methods We investigated selective attention and emotional status in patients with FC using the counting Stroop task.Thirty-five FC patients （FCP group） and 24 healthy controls （HCs） underwent an event-related potential （ERP） study while performing the task.Response time,latency and amplitude of P300 were collected and compared between the two groups.The Hamilton Depression Rating Scale （HAMD-17）,Hamilton Anxiety Scale （HAMA）,Symptom Checklist-90 （SCL-90） and Eysenck Personality Questionnaire （EPQ） were administered prior to the counting Stroop task.Results Scores for the FCP group differed significantly from those for the HCs on the HAMD-17,HAMA,SCL-90 （Global Severity Index,Positive Symptoms Total,dimensions of somatization,obsessive-compulsive,depression,anxiety,and psychosis）,as well as extraversion and neurosis dimensions of the EPQ （P〈0.05）.There was no significant difference in response time or accuracy rate between the two groups （P〉0.05）.ERP results showed prolonged latency at F4,additionally found enhanced activation at F3,FC1 and T8,and decreased activation at sites FC6 and P7 in the patients with FC.Statistically,significant differences of P300 latency at site F4 （P 〈0.05） and P300 amplitude at F3,F4,T8,P7,FC1 and FC6 （P〈0.05） between the patients with FC and the HC were revealed.Conclusions The findings suggest that patients with FC are more susceptible to depression and anxiety,as well as somatization,obsessive-compulsive tendencies and other neurotic personality characteristics.Patients may employ psychological defense mechanisms to avoid the pain of depression and anxiety.ERP results imply there may be some brain dysfunction and a
基金the Shanxi Soft Science Research Program, No. 2008041061-03
文摘Event-related potential studies of cognitive function in addiction behaviors have focused on the P300 event-related potential component. The current study investigated the association between P300 component and Internet addiction disorder. We found that individuals with Internet addiction disorder exhibited significantly longer P300 latencies than controls （N2： P = 0.035; P3a： P = 0.031 P3b： P = 0.043） and similar P300 amplitudes compared to control participants. After 3 months of cognitive behavioral therapy, P300 latencies decreased significantly in the P3a and P3b （P3a： P = 0.045; P3b： P = 0.062）. These results suggest that deficits in cognitive function may be involved in Internet addiction disorder, and that clinical psychological treatment may be effective.
