A polysaccharide named YhPS- 1 was isolated from the root of Cordalis yanhusuo Wang and purified by means of gel-permeation chromatography and ionexchange chromatography. Its physicochemical properties, including mono...A polysaccharide named YhPS- 1 was isolated from the root of Cordalis yanhusuo Wang and purified by means of gel-permeation chromatography and ionexchange chromatography. Its physicochemical properties, including monosaccharide composition, carbohydrate content, molecular weight and elemental composition, were determined. The structure of YhPS-1 was elucidated by chemical methods along with ^1H and ^13C NMR spectroscopy ways, such as including two-dimensional HMQC and HMBC experiments. These results show that YhPS-1 possesses a backbone consisting of terminal α-Glcp-（1→, a-Glcp-（1→6）, a-Glcp-（1→4） and a-Glcp-（1→4,6）. The bioactive assay showed that it could inhibit the growth of Sarcoma 180 and Lewis pulmonary carcinoma implanted in mice.展开更多
文摘A polysaccharide named YhPS- 1 was isolated from the root of Cordalis yanhusuo Wang and purified by means of gel-permeation chromatography and ionexchange chromatography. Its physicochemical properties, including monosaccharide composition, carbohydrate content, molecular weight and elemental composition, were determined. The structure of YhPS-1 was elucidated by chemical methods along with ^1H and ^13C NMR spectroscopy ways, such as including two-dimensional HMQC and HMBC experiments. These results show that YhPS-1 possesses a backbone consisting of terminal α-Glcp-（1→, a-Glcp-（1→6）, a-Glcp-（1→4） and a-Glcp-（1→4,6）. The bioactive assay showed that it could inhibit the growth of Sarcoma 180 and Lewis pulmonary carcinoma implanted in mice.
