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吸烟对食管动力及胃食管反流的影响 被引量:4
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作者 刘维新 陈少夫 +2 位作者 黄茜 傅宝玉 刘雨桃 《中国医科大学学报》 CAS CSCD 北大核心 2001年第5期383-384,共2页
目的 :观察吸烟对食管下段括约肌压力 (loweresophagealsphincterpressure,LESP)、食管体部蠕动波幅度 (peristalsisamplitude,PA)及反流频数 (refluxfrequency ,RF)的影响 ,推断吸烟是否与反流性食管炎发病有关。 方法 :5 1例吸烟者中... 目的 :观察吸烟对食管下段括约肌压力 (loweresophagealsphincterpressure,LESP)、食管体部蠕动波幅度 (peristalsisamplitude,PA)及反流频数 (refluxfrequency ,RF)的影响 ,推断吸烟是否与反流性食管炎发病有关。 方法 :5 1例吸烟者中有 36例反流性食管炎和 15例健康人 ,将他们分别与 36例不吸烟的反流性食管炎患者及 15例不吸烟健康志愿者配对 ,对该 10 2例受试者进行食管动力和 pH值监测。结果 :食管炎患者的LESP及PA显著低于健康人 ,而RF显著高于健康人 (P <0 .0 1和P <0 .0 5 )。食管炎患者中吸烟组LESP及PA低于非吸烟组 ,而RF显著高于非吸烟组 (P <0 .0 1) ,在健康人中吸烟组LESP低于非吸烟组 (P <0 .0 5 ) ,PA及RF与非吸烟组相比无明显差别 (P >0 .0 5 )。结论 :吸烟可降低LESP和PA ,增加RF ,导致食管动力异常 。 展开更多
关键词 吸烟 食管下段扩约肌压力 食管体部蠕动波幅度 反流性食管炎 反流频数
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Swallowing of Casson fluid in oesophagus under the influence of peristaltic waves of varying amplitude 被引量:1
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作者 Sanjay Kumar Pandey Shailendra Kumar Tiwarit 《International Journal of Biomathematics》 2017年第2期49-64,共16页
The experimentally verified fact that there is a high pressure zone in the lower part of the oesophagus has established that the earlier models fall short of representing the realistic swallowing process in the oesoph... The experimentally verified fact that there is a high pressure zone in the lower part of the oesophagus has established that the earlier models fall short of representing the realistic swallowing process in the oesophagus. Since the high pressure is created by gradually increasing amplitudes of peristaltic waves, swallowing of Casson fluid in oesophagus is mathematically remodeled. It is revealed that in the case of exponentially increasing amplitude, pressure is non-uniformly distributed for different cycles. Pressure increases along the entire length of the oesophagus; and finally toward the end of the oesophageal flow, it increases quite significantly, probably to ensure delivery into the stomach. This is a similar observation for Newtonian as well as non-Newtonian fluids but Casson fluids need more pressure; and hence more efforts are required by the oesophagus to transport the fluid forward. When wave amplitude is small, flow rates are small. In such a case, Casson fluid requires higher flow rates for reflux to occur in comparison to Newtonian fluid. This tendency gradually diminishes with increasing amplitude. For a particular value of amplitude, there is no difference; and beyond that the trends are quite opposite. Thus, Casson fluid is found to be less prone to reflux near the wall. It is also concluded that for the Newtonian fluid as well as for the non-Newtonian Casson fluid, reflux is more likely to occur with increasing amplitude and it is further augmented by the addition of amplifying parameter. 展开更多
关键词 OESOPHAGUS peristalsis varying amplitude Casson fluid.
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Peristaltic transport in an elastic tube under the influence of dilating forcing amplitudes
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作者 Sanjay Kumar Pandey Amirlal Singh 《International Journal of Biomathematics》 SCIE 2020年第4期167-179,共13页
We investigate flow through an elastic tube which is constrained to a prescribed external forcing consisting of a progressive travelling wave.Such a flow dynamics is closely related to that in the oesophageal tube.The... We investigate flow through an elastic tube which is constrained to a prescribed external forcing consisting of a progressive travelling wave.Such a flow dynamics is closely related to that in the oesophageal tube.The mechanics of the tube is characterized by a relationship between transmural pressure difference and radial variation of the tube.Dimensionless radial variation,assumed to be small,is studied by perturbation techniques.Hesults demonstrate that the elasticity of the tube plays a significant role in the flow dynamics.An increment in the forcing amplitude of the inward radial force enhances pressure,time-averaged volume flow rate and hence axial and radial velocities.lt is revealed that the elastic nature of the oesophageal tube favors swallowing. 展开更多
关键词 peristalsis OESOPHAGUS elastic tube dilating forcing amplitude
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