Objective To find out several patented technologies of antihypertensive drugs with the most market value through analysis,and provide a reference for the research and development of enterprises.Methods The most valuab...Objective To find out several patented technologies of antihypertensive drugs with the most market value through analysis,and provide a reference for the research and development of enterprises.Methods The most valuable patented technologies of antihypertensive drugs from 2009 to 2019 were analyzed to explore the patent layout and technical characteristics of the main patent applicants,and then the key directions of their research and development were gotten.Results and Conclusion Based on the method of patent analysis,five patents with the most market value are extracted to provide important technical support and market value reference for the research and development of generic drugs or new drugs.展开更多
Objective To explore the extent to which the drug-patent linkage system should be implemented in China. Methods The present situation of drug-patent linkage system internationally was analyzed. Then the practices of d...Objective To explore the extent to which the drug-patent linkage system should be implemented in China. Methods The present situation of drug-patent linkage system internationally was analyzed. Then the practices of drug-patent linkage system were discussed through such methods as literature reviews and quantitative scoring methods in combination of selecting the representative countries. Finally the extent to which the drugpatent linkage system should be implemented in China was explored through comparative analysis. Results and Conclusion Compared with the United States, China should establish a drug-patent linkage system that will weaken the protection of original patented drugs and promote the timely marketing of high-quality generic drugs and appropriately prevent the patent abuse.展开更多
This study is a review of hydrogen station patents using the Derwent Innovation system and also a secondary screening.This was undertaken by the researchers to better understand and identify hydrogen station trends.Th...This study is a review of hydrogen station patents using the Derwent Innovation system and also a secondary screening.This was undertaken by the researchers to better understand and identify hydrogen station trends.The review focuses on analyzing the developing trends of patent technologies associated with a hydrogen station.The results of the review indicated that the countries with the major distribution of patents were Japan,China,the USA and Europe.Japan is leading the developmental trajectory of hydrogen stations.The results of the analysis found the leading developers of these patented technologies are Kobe Steel,Nippon Oil,Toyota and Honda.Other active patent developers analyzed include Linde,Hyundai and Texaco.The review concludes with a suggestion that using a patent analysis methodology is a good starting point to identify,evaluate and measure the trend in hydrogen station commercial development.展开更多
It is wen-known that patented technology licensing is closely related to technology standards, and whether a technology standard contains a specific patented technology solution or not, there is always a patented tech...It is wen-known that patented technology licensing is closely related to technology standards, and whether a technology standard contains a specific patented technology solution or not, there is always a patented technology hcensing imphed, for patented technology hcensing is a prerequisite for the existence and development of technology standards. Therefore, technology standards create a good many potential chances for hcensing patented technologies concerning them. Superficially speaking, patent holders achieve huge profits mainly by means of hcensing patented technologies through a standard mainly in the form of a patent pool; however, in fact, it is know-how licensing behind the patented technology involved in the standard that really helps patent holders make huge profits.展开更多
目的:运用Meta分析的方法系统评价原研与仿制氨氯地平治疗高血压的有效性和安全性。方法:在维普数据库(VIP)、万方数据库(WANFANG)和中国期刊网全文数据库(CNKI)中检索2014年12月25日之前发表的相关文献。在进行文献质量评估基础上提取...目的:运用Meta分析的方法系统评价原研与仿制氨氯地平治疗高血压的有效性和安全性。方法:在维普数据库(VIP)、万方数据库(WANFANG)和中国期刊网全文数据库(CNKI)中检索2014年12月25日之前发表的相关文献。在进行文献质量评估基础上提取文献数据,采用Rev Man 5.3软件进行Meta分析。结果:经过检索并剔除重复文献后共获得62篇文献,最终纳入综述文献4篇。Meta分析结果显示,仿制氨氯地平与原研氨氯地平治疗高血压的有效率RR=0.99(95%CI:0.65,1.52,P=0.97);根据用药剂量、病例纳入标准进行亚组分析;临床研究报道了显效率,合并效应量RR=0.99(95%CI:0.83,1.19,P=0.95);不良反应发生率RR=1.01(95%CI:0.51,1.99,P=0.98)。研究结果显示均无统计学上的显著性差异。结论:仿制氨氯地平有效性和安全性与原研氨氯地平相当,因此仿制氨氯地平在治疗高血压时是安全有效的。展开更多
文摘Objective To find out several patented technologies of antihypertensive drugs with the most market value through analysis,and provide a reference for the research and development of enterprises.Methods The most valuable patented technologies of antihypertensive drugs from 2009 to 2019 were analyzed to explore the patent layout and technical characteristics of the main patent applicants,and then the key directions of their research and development were gotten.Results and Conclusion Based on the method of patent analysis,five patents with the most market value are extracted to provide important technical support and market value reference for the research and development of generic drugs or new drugs.
文摘Objective To explore the extent to which the drug-patent linkage system should be implemented in China. Methods The present situation of drug-patent linkage system internationally was analyzed. Then the practices of drug-patent linkage system were discussed through such methods as literature reviews and quantitative scoring methods in combination of selecting the representative countries. Finally the extent to which the drugpatent linkage system should be implemented in China was explored through comparative analysis. Results and Conclusion Compared with the United States, China should establish a drug-patent linkage system that will weaken the protection of original patented drugs and promote the timely marketing of high-quality generic drugs and appropriately prevent the patent abuse.
文摘This study is a review of hydrogen station patents using the Derwent Innovation system and also a secondary screening.This was undertaken by the researchers to better understand and identify hydrogen station trends.The review focuses on analyzing the developing trends of patent technologies associated with a hydrogen station.The results of the review indicated that the countries with the major distribution of patents were Japan,China,the USA and Europe.Japan is leading the developmental trajectory of hydrogen stations.The results of the analysis found the leading developers of these patented technologies are Kobe Steel,Nippon Oil,Toyota and Honda.Other active patent developers analyzed include Linde,Hyundai and Texaco.The review concludes with a suggestion that using a patent analysis methodology is a good starting point to identify,evaluate and measure the trend in hydrogen station commercial development.
文摘It is wen-known that patented technology licensing is closely related to technology standards, and whether a technology standard contains a specific patented technology solution or not, there is always a patented technology hcensing imphed, for patented technology hcensing is a prerequisite for the existence and development of technology standards. Therefore, technology standards create a good many potential chances for hcensing patented technologies concerning them. Superficially speaking, patent holders achieve huge profits mainly by means of hcensing patented technologies through a standard mainly in the form of a patent pool; however, in fact, it is know-how licensing behind the patented technology involved in the standard that really helps patent holders make huge profits.
文摘目的:运用Meta分析的方法系统评价原研与仿制氨氯地平治疗高血压的有效性和安全性。方法:在维普数据库(VIP)、万方数据库(WANFANG)和中国期刊网全文数据库(CNKI)中检索2014年12月25日之前发表的相关文献。在进行文献质量评估基础上提取文献数据,采用Rev Man 5.3软件进行Meta分析。结果:经过检索并剔除重复文献后共获得62篇文献,最终纳入综述文献4篇。Meta分析结果显示,仿制氨氯地平与原研氨氯地平治疗高血压的有效率RR=0.99(95%CI:0.65,1.52,P=0.97);根据用药剂量、病例纳入标准进行亚组分析;临床研究报道了显效率,合并效应量RR=0.99(95%CI:0.83,1.19,P=0.95);不良反应发生率RR=1.01(95%CI:0.51,1.99,P=0.98)。研究结果显示均无统计学上的显著性差异。结论:仿制氨氯地平有效性和安全性与原研氨氯地平相当,因此仿制氨氯地平在治疗高血压时是安全有效的。
