In this paper,we highlight some recent developments of a new route to evaluate macroeconomic policy effects,which are investigated under the framework with potential outcomes.First,this paper begins with a brief intro...In this paper,we highlight some recent developments of a new route to evaluate macroeconomic policy effects,which are investigated under the framework with potential outcomes.First,this paper begins with a brief introduction of the basic model setup in modern econometric analysis of program evaluation.Secondly,primary attention goes to the focus on causal effect estimation of macroeconomic policy with single time series data together with some extensions to multiple time series data.Furthermore,we examine the connection of this new approach to traditional macroeconomic models for policy analysis and evaluation.Finally,we conclude by addressing some possible future research directions in statistics and econometrics.展开更多
Consider the following Schr？dinger-Poisson-Slater system, （P） where ω 〉 0, λ 〉 0 and β 〉 0 are real numbers, p ∈ （1, 2）. For β=0, it is known that problem （P） has no nontrivial solution if λ 〉 0 suit...Consider the following Schr？dinger-Poisson-Slater system, （P） where ω 〉 0, λ 〉 0 and β 〉 0 are real numbers, p ∈ （1, 2）. For β=0, it is known that problem （P） has no nontrivial solution if λ 〉 0 suitably large. When β 〉 0, -β/｜x｜ is an important potential in physics, which is called external Coulomb potential. In this paper, we find that （P） with β 〉 0 has totally different properties from that of β = 0. For β 〉 0, we prove that （P） has a ground state and multiple solutions if λ 〉 cp,ω, where cp,ω 〉 0 is a constant which can be expressed explicitly via ω and p.展开更多
The use of bacteria to specifically migrate to cancerous tissue and elicit an antitumor immune response provides a promising platform against cancer with significantly high potency.With dozens of clinical trials under...The use of bacteria to specifically migrate to cancerous tissue and elicit an antitumor immune response provides a promising platform against cancer with significantly high potency.With dozens of clinical trials underway,some researchers hold the following views:“humans are nearing the first commercial live bacteria therapeutic.”However,the facultative anaerobe Salmonella typhimurium VNP20009,which is particularly safe and shows anticancer effects in preclinical studies,had failed in a phase I clinical trial due to low tumor regression and undesired dose-dependent side effects.This is almost certain to disappoint people’s inflated expectations,but it is noted that recent stateof-the-art research has turned attention to bacteria-mediated synergistic cancer therapy(BMSCT).In this review,the foundation of bacteria-mediated bio-therapy is outlined.Then,we summarize the potential benefits and challenges of bacterial bio-therapy in combination with different traditional anticancer therapeutic modalities(chemotherapy,photothermal therapy,reactive oxygen and nitrogen species therapy,immunotherapy,or prodrug-activating therapy)in the past 5 years.Next,we discuss multiple administration routes of BMSCT,highlighting potentiated antitumor responses and avoidance of potential side effects.Finally,we envision the opportunities and challenges for BMSCT development,with the purpose of inspiring medicinal scientists to widely utilize the microbiome approach in patient populations.展开更多
In this paper,we use high-precision airborne gravity and magnetic data to study the geophysical characteristics of the western slope of the Songliao Basin and its adjacent areas and evaluate the resource potential.We ...In this paper,we use high-precision airborne gravity and magnetic data to study the geophysical characteristics of the western slope of the Songliao Basin and its adjacent areas and evaluate the resource potential.We performed an in-depth analysis of three aspects of the basin characteristics:the characteristics of residual strata,the development characteristics of faults,and the distribution characteristics of magmatic rocks.Next,we analyzed the forming background of organic(oil and gas)resources and inorganic(uranium ore and hot dry rock)resources.The results showed that the new Upper Paleozoic strata have significant differences in different regions of the study area(with a thickness of 0–8000 m),mainly distributed in the eastern and northern regions but absent in the middle eastern and western regions.Furthermore,the thickness and depth of the Mesozoic layer varied between the eastern and western regions;it was thicker and deeper in the middle eastern region but thinner and shallower in the western region,and it is absent in most western regions.The main faults in the region are in the north–northeast(NNE)direction.Faults in the NE–NNE and NW directions jointly controlled the morphology of the secondary structural units.Magmatic rocks are relatively developed in the middle and eastern parts of the region.Most magmatic rocks are distributed along the faults and their sides,clearly reflecting the control of the faults on magmatic activities.The western slope of the Songliao basin and its surroundings have a favorable geological setting for the accumulation(mineralization)of oil,gas,shale oil,hot dry rock,and uranium ore.It is conducive to oil and gas exploration of deep new strata and collaborative exploration of multiple resources.展开更多
Based on the developed Anderson and Moore's theory about cross-equatorial inertial jets and a nonlinear equivalence shallow water model, new universal functions are determined by the characters of the vortical lar...Based on the developed Anderson and Moore's theory about cross-equatorial inertial jets and a nonlinear equivalence shallow water model, new universal functions are determined by the characters of the vortical large-scale air flow (atmosphere) or ocean current (ocean) related to the jet, then the potential vorticity and energy conservation equations along the streamline in the cross-equatorial in-ertial jets can be obtained. Because the governing equations are nonlinear, some limited multiple equi-libria of cross-equatorial inertial jets may exist. According to the character of large-scale air flow or ocean current outside the jets, the existent criterion for multiple eqnilibria in cross-equatorial inertial jets is discussed, and two examples for multiple equilibia of nonlinear governing equations are given.展开更多
We study the existence of solutions to a class of p(x)-Laplacian equations involving singular Hardy terms for nonlinear terms of the type f(x, t) = ±(-λ|t|m(x)-2t +|t|q(x)-2t). First we show the existence of inf...We study the existence of solutions to a class of p(x)-Laplacian equations involving singular Hardy terms for nonlinear terms of the type f(x, t) = ±(-λ|t|m(x)-2t +|t|q(x)-2t). First we show the existence of infinitely many weak solutions for anyλ 】 0, and next prove that if λ is large enough then there exists a nontrivial weak solution. Our approach relies on direct variational methods and the theory of variable exponent Lebesgue-Sobolev spaces.展开更多
We investigate the alpha-decay half-lives of non-spherical nuclei with the Yukawa potential as the prox- imity potential and an angle-dependent term that accounts for the deformation effects and apply the results to H...We investigate the alpha-decay half-lives of non-spherical nuclei with the Yukawa potential as the prox- imity potential and an angle-dependent term that accounts for the deformation effects and apply the results to Ho, Tb, Lu, Tin, Ta, Hf, Yb, Re, Ir, Pt, Au, Po, etc. as examples. The comparison with the existing data is encouraging.展开更多
基金the National Natural Science Foundation of China(71631004,Key Project)the National Science Fund for Distinguished Young Scholars(71625001)+2 种基金the Basic Scientific Center Project of National Science Foundation of China:Econometrics and Quantitative Policy Evaluation(71988101)the Science Foundation of Ministry of Education of China(19YJA910003)China Scholarship Council Funded Project(201806315045).
文摘In this paper,we highlight some recent developments of a new route to evaluate macroeconomic policy effects,which are investigated under the framework with potential outcomes.First,this paper begins with a brief introduction of the basic model setup in modern econometric analysis of program evaluation.Secondly,primary attention goes to the focus on causal effect estimation of macroeconomic policy with single time series data together with some extensions to multiple time series data.Furthermore,we examine the connection of this new approach to traditional macroeconomic models for policy analysis and evaluation.Finally,we conclude by addressing some possible future research directions in statistics and econometrics.
基金supported by National Natural Science Foundation of China(Grant Nos.11071245,11171339 and 11201486)supported by the Fundamental Research Funds for the Central Universities
文摘Consider the following Schr？dinger-Poisson-Slater system, （P） where ω 〉 0, λ 〉 0 and β 〉 0 are real numbers, p ∈ （1, 2）. For β=0, it is known that problem （P） has no nontrivial solution if λ 〉 0 suitably large. When β 〉 0, -β/｜x｜ is an important potential in physics, which is called external Coulomb potential. In this paper, we find that （P） with β 〉 0 has totally different properties from that of β = 0. For β 〉 0, we prove that （P） has a ground state and multiple solutions if λ 〉 cp,ω, where cp,ω 〉 0 is a constant which can be expressed explicitly via ω and p.
基金Supported by National Natural Science Foundation of China,No.81773656Liaoning Revitalization Talents Program,No.XLYC1808017Shenyang Youth Science and Technology Innovation Talents Program,No.RC190454.
文摘The use of bacteria to specifically migrate to cancerous tissue and elicit an antitumor immune response provides a promising platform against cancer with significantly high potency.With dozens of clinical trials underway,some researchers hold the following views:“humans are nearing the first commercial live bacteria therapeutic.”However,the facultative anaerobe Salmonella typhimurium VNP20009,which is particularly safe and shows anticancer effects in preclinical studies,had failed in a phase I clinical trial due to low tumor regression and undesired dose-dependent side effects.This is almost certain to disappoint people’s inflated expectations,but it is noted that recent stateof-the-art research has turned attention to bacteria-mediated synergistic cancer therapy(BMSCT).In this review,the foundation of bacteria-mediated bio-therapy is outlined.Then,we summarize the potential benefits and challenges of bacterial bio-therapy in combination with different traditional anticancer therapeutic modalities(chemotherapy,photothermal therapy,reactive oxygen and nitrogen species therapy,immunotherapy,or prodrug-activating therapy)in the past 5 years.Next,we discuss multiple administration routes of BMSCT,highlighting potentiated antitumor responses and avoidance of potential side effects.Finally,we envision the opportunities and challenges for BMSCT development,with the purpose of inspiring medicinal scientists to widely utilize the microbiome approach in patient populations.
基金funded by the national geological and mineral resources and environment investigation project (no. DD20190028)。
文摘In this paper,we use high-precision airborne gravity and magnetic data to study the geophysical characteristics of the western slope of the Songliao Basin and its adjacent areas and evaluate the resource potential.We performed an in-depth analysis of three aspects of the basin characteristics:the characteristics of residual strata,the development characteristics of faults,and the distribution characteristics of magmatic rocks.Next,we analyzed the forming background of organic(oil and gas)resources and inorganic(uranium ore and hot dry rock)resources.The results showed that the new Upper Paleozoic strata have significant differences in different regions of the study area(with a thickness of 0–8000 m),mainly distributed in the eastern and northern regions but absent in the middle eastern and western regions.Furthermore,the thickness and depth of the Mesozoic layer varied between the eastern and western regions;it was thicker and deeper in the middle eastern region but thinner and shallower in the western region,and it is absent in most western regions.The main faults in the region are in the north–northeast(NNE)direction.Faults in the NE–NNE and NW directions jointly controlled the morphology of the secondary structural units.Magmatic rocks are relatively developed in the middle and eastern parts of the region.Most magmatic rocks are distributed along the faults and their sides,clearly reflecting the control of the faults on magmatic activities.The western slope of the Songliao basin and its surroundings have a favorable geological setting for the accumulation(mineralization)of oil,gas,shale oil,hot dry rock,and uranium ore.It is conducive to oil and gas exploration of deep new strata and collaborative exploration of multiple resources.
基金Supported by the National Natural Science Foundation of China (Grant No. 4023012)the National Basic Research Program of China (Grant No. 2006cb400500)
文摘Based on the developed Anderson and Moore's theory about cross-equatorial inertial jets and a nonlinear equivalence shallow water model, new universal functions are determined by the characters of the vortical large-scale air flow (atmosphere) or ocean current (ocean) related to the jet, then the potential vorticity and energy conservation equations along the streamline in the cross-equatorial in-ertial jets can be obtained. Because the governing equations are nonlinear, some limited multiple equi-libria of cross-equatorial inertial jets may exist. According to the character of large-scale air flow or ocean current outside the jets, the existent criterion for multiple eqnilibria in cross-equatorial inertial jets is discussed, and two examples for multiple equilibia of nonlinear governing equations are given.
基金supported by Educational Commission of Henan Province(No.14A110013)
文摘We study the existence of solutions to a class of p(x)-Laplacian equations involving singular Hardy terms for nonlinear terms of the type f(x, t) = ±(-λ|t|m(x)-2t +|t|q(x)-2t). First we show the existence of infinitely many weak solutions for anyλ 】 0, and next prove that if λ is large enough then there exists a nontrivial weak solution. Our approach relies on direct variational methods and the theory of variable exponent Lebesgue-Sobolev spaces.
文摘We investigate the alpha-decay half-lives of non-spherical nuclei with the Yukawa potential as the prox- imity potential and an angle-dependent term that accounts for the deformation effects and apply the results to Ho, Tb, Lu, Tin, Ta, Hf, Yb, Re, Ir, Pt, Au, Po, etc. as examples. The comparison with the existing data is encouraging.
