Background:Allergy march refers to progression of allergic diseases from infantile food allergy to the development of asthma and allergic rhinitis (AR).Evidence come mostly from studies in European countries.This stud...Background:Allergy march refers to progression of allergic diseases from infantile food allergy to the development of asthma and allergic rhinitis (AR).Evidence come mostly from studies in European countries.This study aimed to investigate allergy march in Chinese children with infantile food protein allergy (FPA) with a special focus on the effect of different formula interventions.Methods:From 2008 to 2010,153 infants diagnosed with FPA were recruited in five tertiary hospitals across China.They were randomly treated with amino-acid-based formula or soy-protein-based formula for a period of 3 months.Long-term follow-up was performed when they reached early school age,using questionnaires,physical examinations,and serum-specific immunoglobulin E.Results:The overall follow-up rate was 73.20%.In patients who reached their early school years,the prevalence of physician-diagnosed AR and asthma were 43.75% and 23.21%,respectively.Only 40% of the subjects remained positive for food sensitizations upon follow-up.Twenty-six subjects receiving aeroallergen screening tests in infancy all proved negative,but upon follow-up,65.57% were sensitized to aeroallergens (P=0.005).No significant difference between the effects of amino-acid-based formula and soy-protein-based formula on children's allergy march was observed.Conclusions:A high proportion (47.32%) of Chinese infants with early allergic symptoms developed respiratory allergies by their early school years.Most food-sensitized infants outgrew their condition several years later,but then aeroallergen sensitization often occurred.Amino-acid-based formula showed no advantages over soy protein-based formula with respect to arresting the allergy march.展开更多
The anomalous behavior of the western Pacific subtropical high （WPSH） in E1 Nifio developing summer is studied based on the composite results of eight major E1 Nifio events during 1979-2013. It is shown that the WPS...The anomalous behavior of the western Pacific subtropical high （WPSH） in E1 Nifio developing summer is studied based on the composite results of eight major E1 Nifio events during 1979-2013. It is shown that the WPSH tends to retreat eastwards with weak intensity during the developing summer. The anomaly exhibits an intraseasonal variation with a weaker anomaly in June and July and a stronger anomaly in August, indicating that different underlying physical mechanisms may be responsible for the anomalous WPSH during early and late summer periods. In June and July, owing to the cold advection anomaly characterized as a weak northerly anomaly from high latitudes, geopotential height in East Asia is reduced and the WPSH tends to retreat eastwards slightly. By contrast, enhanced convection over the warm pool in August makes the atmosphere more sensitive to E1 Nifio forcing. Consequently, a cyclonic anomaly in the western Pacific is induced, which is consistent with the seasonal march of atmospheric circulation from July to August. Accordingly, geopotential height in the western Pacific is reduced significantly, and the WPSH tends to retreat eastwards remarkably in August. Different from the developing summer, geopotential height in the decaying summer over East Asia and the western Pacific tends to enhance and extend northwards from June to August consistently, reaching the maximum anomaly in August. Therefore, the seasonal march plays an important role in the WPSH anomaly for both the developing and decaying summer.展开更多
The world’s energy is in the "third major transformation period" from fossil energy to new energy, and all countries in the world have formulated energy development strategies. Through advanced deployment, ...The world’s energy is in the "third major transformation period" from fossil energy to new energy, and all countries in the world have formulated energy development strategies. Through advanced deployment, the United States is about to achieve "energy independence" relying on "unconventional oil and gas revolution". China’s energy development is faced with four challenges:(1) The population base and economic development scale determine the "totally huge amount" of energy consumption;(2) the "coal rich but oil and gas insufficient" resource structure determines the "unclean" energy consuming structure;(3) the increasing dependence on imported oil and gas determines the "unsafe" energy supply;and(4) the unconventional oil and gas endowment makes it impossible to achieve energy independence by copying the American model. From the perspective of the world energy trend and the unique situation of China’s energy, we put forward a "three-step" strategy for China to achieve "energy independence": From 2020 to 2035, "energy supply security" will be addressed by "cleaning coal, stabilizing oil and gas production and vigorously developing new alternative energy";from 2035 to 2050, the vision of "production independence" will be realized by relying on "domestic production and overseas oil and gas mining rights";from 2050 to 2100, "intelligent energy and new energy" will help China realize "energy independence". The two important signs of China’s "energy independence" are that domestic production accounts for more than 90% of the domestic consumption and clean energy production accounts for more than 70%, and energy security realizes "independence and self-control" and "long-term security". The strategic significance of "energy independence" is to ensure national energy security, drive the development of relevant major industries, achieve energy management reform, and implement the environmental protection goal of zero carbon emissions. The "energy independence" of China is a strategic mission, it might be fulfilled i展开更多
文摘Background:Allergy march refers to progression of allergic diseases from infantile food allergy to the development of asthma and allergic rhinitis (AR).Evidence come mostly from studies in European countries.This study aimed to investigate allergy march in Chinese children with infantile food protein allergy (FPA) with a special focus on the effect of different formula interventions.Methods:From 2008 to 2010,153 infants diagnosed with FPA were recruited in five tertiary hospitals across China.They were randomly treated with amino-acid-based formula or soy-protein-based formula for a period of 3 months.Long-term follow-up was performed when they reached early school age,using questionnaires,physical examinations,and serum-specific immunoglobulin E.Results:The overall follow-up rate was 73.20%.In patients who reached their early school years,the prevalence of physician-diagnosed AR and asthma were 43.75% and 23.21%,respectively.Only 40% of the subjects remained positive for food sensitizations upon follow-up.Twenty-six subjects receiving aeroallergen screening tests in infancy all proved negative,but upon follow-up,65.57% were sensitized to aeroallergens (P=0.005).No significant difference between the effects of amino-acid-based formula and soy-protein-based formula on children's allergy march was observed.Conclusions:A high proportion (47.32%) of Chinese infants with early allergic symptoms developed respiratory allergies by their early school years.Most food-sensitized infants outgrew their condition several years later,but then aeroallergen sensitization often occurred.Amino-acid-based formula showed no advantages over soy protein-based formula with respect to arresting the allergy march.
基金supported by the National Science Foundation of China (Grant Nos. 41475052 and 41630530)
文摘The anomalous behavior of the western Pacific subtropical high （WPSH） in E1 Nifio developing summer is studied based on the composite results of eight major E1 Nifio events during 1979-2013. It is shown that the WPSH tends to retreat eastwards with weak intensity during the developing summer. The anomaly exhibits an intraseasonal variation with a weaker anomaly in June and July and a stronger anomaly in August, indicating that different underlying physical mechanisms may be responsible for the anomalous WPSH during early and late summer periods. In June and July, owing to the cold advection anomaly characterized as a weak northerly anomaly from high latitudes, geopotential height in East Asia is reduced and the WPSH tends to retreat eastwards slightly. By contrast, enhanced convection over the warm pool in August makes the atmosphere more sensitive to E1 Nifio forcing. Consequently, a cyclonic anomaly in the western Pacific is induced, which is consistent with the seasonal march of atmospheric circulation from July to August. Accordingly, geopotential height in the western Pacific is reduced significantly, and the WPSH tends to retreat eastwards remarkably in August. Different from the developing summer, geopotential height in the decaying summer over East Asia and the western Pacific tends to enhance and extend northwards from June to August consistently, reaching the maximum anomaly in August. Therefore, the seasonal march plays an important role in the WPSH anomaly for both the developing and decaying summer.
基金Supported by the National Natural Science Foundation of China(41902151)
文摘The world’s energy is in the "third major transformation period" from fossil energy to new energy, and all countries in the world have formulated energy development strategies. Through advanced deployment, the United States is about to achieve "energy independence" relying on "unconventional oil and gas revolution". China’s energy development is faced with four challenges:(1) The population base and economic development scale determine the "totally huge amount" of energy consumption;(2) the "coal rich but oil and gas insufficient" resource structure determines the "unclean" energy consuming structure;(3) the increasing dependence on imported oil and gas determines the "unsafe" energy supply;and(4) the unconventional oil and gas endowment makes it impossible to achieve energy independence by copying the American model. From the perspective of the world energy trend and the unique situation of China’s energy, we put forward a "three-step" strategy for China to achieve "energy independence": From 2020 to 2035, "energy supply security" will be addressed by "cleaning coal, stabilizing oil and gas production and vigorously developing new alternative energy";from 2035 to 2050, the vision of "production independence" will be realized by relying on "domestic production and overseas oil and gas mining rights";from 2050 to 2100, "intelligent energy and new energy" will help China realize "energy independence". The two important signs of China’s "energy independence" are that domestic production accounts for more than 90% of the domestic consumption and clean energy production accounts for more than 70%, and energy security realizes "independence and self-control" and "long-term security". The strategic significance of "energy independence" is to ensure national energy security, drive the development of relevant major industries, achieve energy management reform, and implement the environmental protection goal of zero carbon emissions. The "energy independence" of China is a strategic mission, it might be fulfilled i
