A National Science Foundation of China （NSFC） major research project, Destruction of the North China Craton （NCC）, has been carried out in the past few years by Chinese scientists through an in-depth and systemati...A National Science Foundation of China （NSFC） major research project, Destruction of the North China Craton （NCC）, has been carried out in the past few years by Chinese scientists through an in-depth and systematic observations, experiments and theoretical analyses, with an emphasis on the spatio-temporal distribution of the NCC destruction, the structure of deep earth and shallow geological records of the craton evolution, the mechanism and dynamics of the craton destruction. From this work the foUowing conclusions can be drawn： （1） Significant spatial heterogeneity exists in the NCC lithospheric thickness and crustal structure, which constrains the scope of the NCC destruction. （2） The nature of the Paleozoic, Mesozoic and Cenozoic sub-continental lithospheric mantle （CLM） underneath the NCC is characterized in detail. In terms of water content, the late Mesozoic CLM was rich in water, but Cenozoic CLM was highly water deficient. （3） The correlation between magmatism and surface geological response confirms that the geological and tectonic evolution is governed by cratonic destruction processes. （4） Pacific subduction is the main dynamic factor that triggered the destruction of the NCC, which highlights the role of cratonic destruction in plate tectonics.展开更多
Land use/cover change is an important theme on the impacts of human activities on the earth systems and global environmental change. National land-use changes of China during 2010–2015 were acquired by the digital in...Land use/cover change is an important theme on the impacts of human activities on the earth systems and global environmental change. National land-use changes of China during 2010–2015 were acquired by the digital interpretation method using the high-resolution remotely sensed images, e.g. the Landsat 8 OLI, GF-2 remote sensing images. The spatiotemporal characteristics of land-use changes across China during 2010–2015 were revealed by the indexes of dynamic degree model, annual land-use changes ratio etc. The results indicated that the built-up land increased by 24.6×10~3 km^2 while the cropland decreased by 4.9×10~3 km^2, and the total area of woodland and grassland decreased by 16.4×10~3 km^2. The spatial pattern of land-use changes in China during 2010–2015 was concordant with that of the period 2000–2010. Specially, new characteristics of land-use changes emerged in different regions of China in 2010–2015. The built-up land in eastern China expanded continually, and the total area of cropland decreased, both at decreasing rates. The rates of built-up land expansion and cropland shrinkage were accelerated in central China. The rates of built-up land expansion and cropland growth increased in western China, while the decreasing rate of woodland and grassland accelerated. In northeastern China, built-up land expansion slowed continually, and cropland area increased slightly accompanied by the conversions between paddy land and dry land. Besides, woodland and grassland area decreased in northeastern China. The characteristics of land-use changes in eastern China were essentially consistent with the spatial govern and control requirements of the optimal development zones and key development zones according to the Major Function-oriented Zones Planning implemented during the 12 th Five-Year Plan(2011–2015). It was a serious challenge for the central government of China to effectively protect the reasonable layout of land use types dominated with the key ecological function zones and agricultural pro展开更多
Background Primary percutaneous coronary intervention （PCI） has been identified as the first therapeutic option for patients with acute ST-segment elevation myocardial infarction （STEMI）. The strategy of transferr...Background Primary percutaneous coronary intervention （PCI） has been identified as the first therapeutic option for patients with acute ST-segment elevation myocardial infarction （STEMI）. The strategy of transferring patient to a PCI center was recently recommended for those with acute STEMI who were present to PCI incapable hospitals, which include lack of facilities or experienced operators. In China, some local hospitals have been equipped with PCI facilities, but they have no interventional physicians qualified for performing primary PCI. This study was conducted to assess the feasibility, safety and efficacy of the strategy of transferring physician to a PCI-equipped hospital to perform primary PCI for patients with acute STEMI. Methods Three hundred and thirty-four consecutive STEMI patients with symptom presentation 〈12 hours in five local hospitals from November 2005 to November 2007 were randomized to receive primary PCI by either physician transfer （physician transfer group, n=165） or patient transfer （patient transfer group, n=169） strategy. Door-to-balloon time, in-hospital and 30-day major adverse cardiac events （MACE, including death, non-fatal re-infarction, and target vessel revascularization） were compared between the two groups. Results Baseline characteristics between the two groups were comparable. Thrombolysis in myocardial infarction （TIMI） 3 flow was revealed in more patients in the physician transfer group at initial angiography （17.6% vs 10.1%, P〈0.05）. The success rate of primary PCI （96.3% vs 95.4%, P〉0.05） and length of hospital stay were similar between the two groups （（15±4） days vs （14±3） days, P〉0.05）. In the physician transfer group, door-to-balloon time was significantly shortened （（95±20） minutes vs （147±29） minutes, P〈0.0001） and more patients received primary PCI with door-to-balloon time less than 90 minutes （21.2% vs 7.7%, P〈0.001）. During hospitalization, MACE occurred in 6.7% and 11.2% of patients 展开更多
AIM:To investigate the effect of preoperative biliary drainage(PBD)in jaundiced patients with hilar cholangiocarcinoma(HCCA)undergoing major liver resections.METHODS:An observational study was carried out by reviewing...AIM:To investigate the effect of preoperative biliary drainage(PBD)in jaundiced patients with hilar cholangiocarcinoma(HCCA)undergoing major liver resections.METHODS:An observational study was carried out by reviewing a prospectively maintained database of HCCA patients who underwent major liver resection for curative therapy from January 2002 to December 2012.Patients were divided into two groups based on whether PBD was performed:a drained group and an undrained group.Patient baseline characteristics,preoperative factors,perioperative and short-term postoperative outcomes were compared between the two groups.Risk factors for postoperative complications were also analyzed by logistic regression test with calculating OR and 95%CI.RESULTS:In total,78 jaundiced patients with HCCA underwent major liver resection:32 had PBD prior to operation while 46 did not have PBD.The two groups were comparable with respect to age,sex,body mass index and co-morbidities.Furthermore,there was no significant difference in the total bilirubin(TBIL)levels between the drained group and the undrained group at admission(294.2±135.7 vs 254.0±63.5,P=0.126).PBD significantly improved liver function,reducing not only the bilirubin levels but also other liver enzymes.The preoperative TBIL level was significantly lower in the drained group as compared to the undrained group(108.1±60.6 vs 265.7±69.1,P=0.000).The rate of overall postoperative complications(53.1%vs 58.7%,P=0.626),reoperation rate(6.3%vs 6.5%,P=1.000),postoperative hospital stay(16.5 vs 15.0,P=0.221)and mortality(9.4%vs 4.3%,P=0.673)were similar between the two groups.In addition,there was no significant difference in infectious complications(40.6%vs 23.9%,P=0.116)and noninfectious complications(31.3%vs 47.8%,P=0.143)between the two groups.Univariate and multivariate analyses revealed that preoperative TBIL>170μmol/L(OR=13.690,95%CI:1.275-147.028,P=0.031),Bismuth-Corlette classification(OR=0.013,95%CI:0.001-0.166,P=0.001)and extended liver resection(OR=14.010,95%CI:1.130-173.展开更多
How ophiolitic mèlanges can be defined as sutures is controversial with regard to accretionary orogenesis and continental growth.The Chinese Altay,East junggar,Tianshan,and Beishan belts of the southern Central A...How ophiolitic mèlanges can be defined as sutures is controversial with regard to accretionary orogenesis and continental growth.The Chinese Altay,East junggar,Tianshan,and Beishan belts of the southern Central Asian Orogenic Belt（CAOB） in Northwest China,offer a special natural laboratory to resolve this puzzle.In the Chinese Altay,the Erqis unit consists of ophiolitic melanges and coherent assemblages,forming a Paleozoic accretionary complex.At least two ophiolitic melanges（Armantai,and Kelameili） in East Junggar,characterized by imbricated ophiolitic melanges,Nb-enriched basalts,adakitic rocks and volcanic rocks,belong to a Devonian-Carboniferous intra-oceanic island arc with some Paleozoic ophiolites,superimposed by Permian arc volcanism.In the Tianshan,ophiolitic melanges like Kanggurtag,North Tianshan,and South Tianshan occur as part of some Paleozoic accretionary complexes related to amalgamation of arc terranes.In the Beishan there are also several ophiolitic melanges,including the Hongshishan,Xingxingxia-Shibangjing,Hongliuhe-Xichangjing,and Liuyuan ophiolitic units.Most ophiolitic melanges in the study area are characterized by ultramafic,mafic and other components,which are juxtaposed,or even emplaced as lenses and knockers in a matrix of some coherent units.The tectonic settings of various components are different,and some adjacent units in the same melange show contrasting different tectonic settings.The formation ages of these various components are in a wide spectrum,varying from Neoproterozoic to Permian.Therefore we cannot assume that these ophiolitic melanges always form in linear sutures as a result of the closure of specific oceans.Often the ophiolitic components formed either as the substrate of intra-oceanic arcs,or were accreted as lenses or knockers in subduction-accretion complexes.Using published age and paleogeographic constraints,we propose the presence of （1） a major early Paleozoic tectonic boundary that separates the Chinese Altay-East Junggar multiple subduction system展开更多
Newest planning methods implemented by Chinese government are promoting a coordinated regional development and shaping an orderly spatial structure by applying the regulation of territorial function. This article anal...Newest planning methods implemented by Chinese government are promoting a coordinated regional development and shaping an orderly spatial structure by applying the regulation of territorial function. This article analyzes the problems of spatial planning and regional strategy caused by the wrongly-set primary goal of economic development; it states that the three-fold objective of competitiveness, sustainability, and welfare fairness shall be the principal for China to implement the spatial regulation in the new era; it discusses about theoretical thoughts and technology framework of conducting the ′Major Function Oriented Zone′ based on their different major functions that each region plays in urbanization and industrialization, ecological constructions, grain productions, and protection of natural and cultural heritages; it introduces the new concept of ′Major Function Oriented Zone′ that include the major functions category, the stereo regional equilibrium mode, the two-level zoning specification, and the territorial development intensity; it offers a zoning scheme that defines development-optimized and development-prioritized zones as regions with massive urbanization and industrialization, development-restricted zones as ecological constructing or grain producing regions, development-prohibited zones as natural and cultural heritage protecting regions; and finally it addresses the main obstacle for implementing ′Major Function Oriented Zone′, which is the institutional arrangement of the supreme goal of high GDP growth rate that is currently being implemented.展开更多
An insertion fragment in porcine FSHβ subunit gene was cloned by PCR. Sequencing data show that the insertion is a retroposon of 292 bp siting in intronⅠ at the site between +809 and +810 base. Based on these result...An insertion fragment in porcine FSHβ subunit gene was cloned by PCR. Sequencing data show that the insertion is a retroposon of 292 bp siting in intronⅠ at the site between +809 and +810 base. Based on these results, a PCR programme was created to genotype animal individuals in different pig breeds at FSHβ locus and polymorphism of FSHβ gene was analyzed. With the combination of genotype and litter size of sows, it was demonstrated that FSHβ locus is closely associated with major gene controlling litter size in commercial pig breeds, such as Yorkshire, Landrace, Durco. Averagely the AA sows give more 1.5 piglets than BB sows do per litter.展开更多
基金supported by National Natural Science Foundation of China (Grant Nos.90714001,90714004,90714008,90714009,91014006,91114206)
文摘A National Science Foundation of China （NSFC） major research project, Destruction of the North China Craton （NCC）, has been carried out in the past few years by Chinese scientists through an in-depth and systematic observations, experiments and theoretical analyses, with an emphasis on the spatio-temporal distribution of the NCC destruction, the structure of deep earth and shallow geological records of the craton evolution, the mechanism and dynamics of the craton destruction. From this work the foUowing conclusions can be drawn： （1） Significant spatial heterogeneity exists in the NCC lithospheric thickness and crustal structure, which constrains the scope of the NCC destruction. （2） The nature of the Paleozoic, Mesozoic and Cenozoic sub-continental lithospheric mantle （CLM） underneath the NCC is characterized in detail. In terms of water content, the late Mesozoic CLM was rich in water, but Cenozoic CLM was highly water deficient. （3） The correlation between magmatism and surface geological response confirms that the geological and tectonic evolution is governed by cratonic destruction processes. （4） Pacific subduction is the main dynamic factor that triggered the destruction of the NCC, which highlights the role of cratonic destruction in plate tectonics.
基金National Key Research and Development Program,No.2017YFC0506501National Key Basic Research Program of China,No.2014CB954302
文摘Land use/cover change is an important theme on the impacts of human activities on the earth systems and global environmental change. National land-use changes of China during 2010–2015 were acquired by the digital interpretation method using the high-resolution remotely sensed images, e.g. the Landsat 8 OLI, GF-2 remote sensing images. The spatiotemporal characteristics of land-use changes across China during 2010–2015 were revealed by the indexes of dynamic degree model, annual land-use changes ratio etc. The results indicated that the built-up land increased by 24.6×10~3 km^2 while the cropland decreased by 4.9×10~3 km^2, and the total area of woodland and grassland decreased by 16.4×10~3 km^2. The spatial pattern of land-use changes in China during 2010–2015 was concordant with that of the period 2000–2010. Specially, new characteristics of land-use changes emerged in different regions of China in 2010–2015. The built-up land in eastern China expanded continually, and the total area of cropland decreased, both at decreasing rates. The rates of built-up land expansion and cropland shrinkage were accelerated in central China. The rates of built-up land expansion and cropland growth increased in western China, while the decreasing rate of woodland and grassland accelerated. In northeastern China, built-up land expansion slowed continually, and cropland area increased slightly accompanied by the conversions between paddy land and dry land. Besides, woodland and grassland area decreased in northeastern China. The characteristics of land-use changes in eastern China were essentially consistent with the spatial govern and control requirements of the optimal development zones and key development zones according to the Major Function-oriented Zones Planning implemented during the 12 th Five-Year Plan(2011–2015). It was a serious challenge for the central government of China to effectively protect the reasonable layout of land use types dominated with the key ecological function zones and agricultural pro
文摘Background Primary percutaneous coronary intervention （PCI） has been identified as the first therapeutic option for patients with acute ST-segment elevation myocardial infarction （STEMI）. The strategy of transferring patient to a PCI center was recently recommended for those with acute STEMI who were present to PCI incapable hospitals, which include lack of facilities or experienced operators. In China, some local hospitals have been equipped with PCI facilities, but they have no interventional physicians qualified for performing primary PCI. This study was conducted to assess the feasibility, safety and efficacy of the strategy of transferring physician to a PCI-equipped hospital to perform primary PCI for patients with acute STEMI. Methods Three hundred and thirty-four consecutive STEMI patients with symptom presentation 〈12 hours in five local hospitals from November 2005 to November 2007 were randomized to receive primary PCI by either physician transfer （physician transfer group, n=165） or patient transfer （patient transfer group, n=169） strategy. Door-to-balloon time, in-hospital and 30-day major adverse cardiac events （MACE, including death, non-fatal re-infarction, and target vessel revascularization） were compared between the two groups. Results Baseline characteristics between the two groups were comparable. Thrombolysis in myocardial infarction （TIMI） 3 flow was revealed in more patients in the physician transfer group at initial angiography （17.6% vs 10.1%, P〈0.05）. The success rate of primary PCI （96.3% vs 95.4%, P〉0.05） and length of hospital stay were similar between the two groups （（15±4） days vs （14±3） days, P〉0.05）. In the physician transfer group, door-to-balloon time was significantly shortened （（95±20） minutes vs （147±29） minutes, P〈0.0001） and more patients received primary PCI with door-to-balloon time less than 90 minutes （21.2% vs 7.7%, P〈0.001）. During hospitalization, MACE occurred in 6.7% and 11.2% of patients
文摘AIM:To investigate the effect of preoperative biliary drainage(PBD)in jaundiced patients with hilar cholangiocarcinoma(HCCA)undergoing major liver resections.METHODS:An observational study was carried out by reviewing a prospectively maintained database of HCCA patients who underwent major liver resection for curative therapy from January 2002 to December 2012.Patients were divided into two groups based on whether PBD was performed:a drained group and an undrained group.Patient baseline characteristics,preoperative factors,perioperative and short-term postoperative outcomes were compared between the two groups.Risk factors for postoperative complications were also analyzed by logistic regression test with calculating OR and 95%CI.RESULTS:In total,78 jaundiced patients with HCCA underwent major liver resection:32 had PBD prior to operation while 46 did not have PBD.The two groups were comparable with respect to age,sex,body mass index and co-morbidities.Furthermore,there was no significant difference in the total bilirubin(TBIL)levels between the drained group and the undrained group at admission(294.2±135.7 vs 254.0±63.5,P=0.126).PBD significantly improved liver function,reducing not only the bilirubin levels but also other liver enzymes.The preoperative TBIL level was significantly lower in the drained group as compared to the undrained group(108.1±60.6 vs 265.7±69.1,P=0.000).The rate of overall postoperative complications(53.1%vs 58.7%,P=0.626),reoperation rate(6.3%vs 6.5%,P=1.000),postoperative hospital stay(16.5 vs 15.0,P=0.221)and mortality(9.4%vs 4.3%,P=0.673)were similar between the two groups.In addition,there was no significant difference in infectious complications(40.6%vs 23.9%,P=0.116)and noninfectious complications(31.3%vs 47.8%,P=0.143)between the two groups.Univariate and multivariate analyses revealed that preoperative TBIL>170μmol/L(OR=13.690,95%CI:1.275-147.028,P=0.031),Bismuth-Corlette classification(OR=0.013,95%CI:0.001-0.166,P=0.001)and extended liver resection(OR=14.010,95%CI:1.130-173.
基金financially supported by the Chinese National Basic Research 973 Program(2012CB416604,2007CB411307)the National Natural Science Foundation of China(41230207,41390441,41190075)the One Hundred Talent Program B of the Chinese Academy of Sciences
文摘How ophiolitic mèlanges can be defined as sutures is controversial with regard to accretionary orogenesis and continental growth.The Chinese Altay,East junggar,Tianshan,and Beishan belts of the southern Central Asian Orogenic Belt（CAOB） in Northwest China,offer a special natural laboratory to resolve this puzzle.In the Chinese Altay,the Erqis unit consists of ophiolitic melanges and coherent assemblages,forming a Paleozoic accretionary complex.At least two ophiolitic melanges（Armantai,and Kelameili） in East Junggar,characterized by imbricated ophiolitic melanges,Nb-enriched basalts,adakitic rocks and volcanic rocks,belong to a Devonian-Carboniferous intra-oceanic island arc with some Paleozoic ophiolites,superimposed by Permian arc volcanism.In the Tianshan,ophiolitic melanges like Kanggurtag,North Tianshan,and South Tianshan occur as part of some Paleozoic accretionary complexes related to amalgamation of arc terranes.In the Beishan there are also several ophiolitic melanges,including the Hongshishan,Xingxingxia-Shibangjing,Hongliuhe-Xichangjing,and Liuyuan ophiolitic units.Most ophiolitic melanges in the study area are characterized by ultramafic,mafic and other components,which are juxtaposed,or even emplaced as lenses and knockers in a matrix of some coherent units.The tectonic settings of various components are different,and some adjacent units in the same melange show contrasting different tectonic settings.The formation ages of these various components are in a wide spectrum,varying from Neoproterozoic to Permian.Therefore we cannot assume that these ophiolitic melanges always form in linear sutures as a result of the closure of specific oceans.Often the ophiolitic components formed either as the substrate of intra-oceanic arcs,or were accreted as lenses or knockers in subduction-accretion complexes.Using published age and paleogeographic constraints,we propose the presence of （1） a major early Paleozoic tectonic boundary that separates the Chinese Altay-East Junggar multiple subduction system
基金Under the auspices of Key Project of National Natural Science Foundation of China (No. 40830741)National Key Technology R&D Program (No. 2008BAH31B01)
文摘Newest planning methods implemented by Chinese government are promoting a coordinated regional development and shaping an orderly spatial structure by applying the regulation of territorial function. This article analyzes the problems of spatial planning and regional strategy caused by the wrongly-set primary goal of economic development; it states that the three-fold objective of competitiveness, sustainability, and welfare fairness shall be the principal for China to implement the spatial regulation in the new era; it discusses about theoretical thoughts and technology framework of conducting the ′Major Function Oriented Zone′ based on their different major functions that each region plays in urbanization and industrialization, ecological constructions, grain productions, and protection of natural and cultural heritages; it introduces the new concept of ′Major Function Oriented Zone′ that include the major functions category, the stereo regional equilibrium mode, the two-level zoning specification, and the territorial development intensity; it offers a zoning scheme that defines development-optimized and development-prioritized zones as regions with massive urbanization and industrialization, development-restricted zones as ecological constructing or grain producing regions, development-prohibited zones as natural and cultural heritage protecting regions; and finally it addresses the main obstacle for implementing ′Major Function Oriented Zone′, which is the institutional arrangement of the supreme goal of high GDP growth rate that is currently being implemented.
文摘An insertion fragment in porcine FSHβ subunit gene was cloned by PCR. Sequencing data show that the insertion is a retroposon of 292 bp siting in intronⅠ at the site between +809 and +810 base. Based on these results, a PCR programme was created to genotype animal individuals in different pig breeds at FSHβ locus and polymorphism of FSHβ gene was analyzed. With the combination of genotype and litter size of sows, it was demonstrated that FSHβ locus is closely associated with major gene controlling litter size in commercial pig breeds, such as Yorkshire, Landrace, Durco. Averagely the AA sows give more 1.5 piglets than BB sows do per litter.
