Virtual reality is nowadays used to facilitate motor recovery in stroke patients. Most virtual reality studies have involved chronic stroke patients; however, brain plasticity remains good in acute and subacute patien...Virtual reality is nowadays used to facilitate motor recovery in stroke patients. Most virtual reality studies have involved chronic stroke patients; however, brain plasticity remains good in acute and subacute patients. Most virtual reality systems are only applicable to the proximal upper limbs (arms) because of the limitations of their capture systems. Nevertheless, the functional recovery of an affected hand is most difficult in the case of hemiparesis rehabilitation after a stroke. The recently developed Leap Motion controller can track the fine movements of both hands and fingers. Therefore, the present study explored the effects of a Leap Motion-based virtual reality system on subacute stroke. Twenty-six subacute stroke patients were assigned to an experimental group that received virtual reality training along with conventional occupational rehabilitation, and a control group that only received conventional rehabilitation. The Wolf motor func- tion test (WMFT) was used to assess the motor function of the affected upper limb; functional magnetic resonance imaging was used to measure the cortical activation. After four weeks of treatment, the motor functions of the affected upper limbs were significantly improved in all the patients, with the improvement in the experimental group being significantly better than in the control group. The action perfor- mance time in the WMFT significantly decreased in the experimental group. Furthermore, the activation intensity and the laterality index of the contralateral primary sensorimotor cortex increased in both the experimental and control groups. These results confirmed that Leap Motion-based virtual reality training was a promising and feasible supplementary rehabilitation intervention, could facilitate the recovery of motor functions in subacute stroke patients. The study has been registered in the Chinese Clinical Trial Registry (registration number: ChiCTR-OCH- 12002238).展开更多
设计一种磁共振成像(MRI)检查肢体隔离固定装置,用于3.0 TMRI检查时减少热效应对人体损伤,并解决运动性伪影现象。选取2020年9-10月在医院行3.0 T MRI检查的5768例患者,随机分为对照组和观察组,每组2884例,对照组患者执行常规MRI检查流...设计一种磁共振成像(MRI)检查肢体隔离固定装置,用于3.0 TMRI检查时减少热效应对人体损伤,并解决运动性伪影现象。选取2020年9-10月在医院行3.0 T MRI检查的5768例患者,随机分为对照组和观察组,每组2884例,对照组患者执行常规MRI检查流程,观察组患者在常规MRI检查流程前使用肢体隔离固定装置,将患者肢体进行隔离固定后进行检查。比较两组患者检查过程中的热效应(灼伤)现象和图像伪影发生率,对照组患者共出现12例热效应现象,其中1例出现灼伤点,热效应率为0.41%,对照组图像出现伪影207例,不可技术处理的伪影图像29例,伪影率为7.17%;观察组患者共出现5例发热现象,热效应率为0.17%,观察组图像出现轻微伪影36例,伪影率为1.24%,观察组患者热效应率和图像伪影率明显优于对照组患者,其差异具有统计学意义(x^(2) =2.112,x^(2) =1.036;P<0.05)。肢体隔离固定装置能有效减少和避免射频能量和肢体皮肤接触导致涡流热效应及肢体运动性伪影的产生,可提高患者检查安全度和工作效率。展开更多
基金supported by the Sub-Project under National "Twelfth Five-Year" Plan for Science&Technology Support Project in China,No.2011BAI08B11the Research Project of China Rehabilitation Research Center,No.2014-3
文摘Virtual reality is nowadays used to facilitate motor recovery in stroke patients. Most virtual reality studies have involved chronic stroke patients; however, brain plasticity remains good in acute and subacute patients. Most virtual reality systems are only applicable to the proximal upper limbs (arms) because of the limitations of their capture systems. Nevertheless, the functional recovery of an affected hand is most difficult in the case of hemiparesis rehabilitation after a stroke. The recently developed Leap Motion controller can track the fine movements of both hands and fingers. Therefore, the present study explored the effects of a Leap Motion-based virtual reality system on subacute stroke. Twenty-six subacute stroke patients were assigned to an experimental group that received virtual reality training along with conventional occupational rehabilitation, and a control group that only received conventional rehabilitation. The Wolf motor func- tion test (WMFT) was used to assess the motor function of the affected upper limb; functional magnetic resonance imaging was used to measure the cortical activation. After four weeks of treatment, the motor functions of the affected upper limbs were significantly improved in all the patients, with the improvement in the experimental group being significantly better than in the control group. The action perfor- mance time in the WMFT significantly decreased in the experimental group. Furthermore, the activation intensity and the laterality index of the contralateral primary sensorimotor cortex increased in both the experimental and control groups. These results confirmed that Leap Motion-based virtual reality training was a promising and feasible supplementary rehabilitation intervention, could facilitate the recovery of motor functions in subacute stroke patients. The study has been registered in the Chinese Clinical Trial Registry (registration number: ChiCTR-OCH- 12002238).