The 12-lead electrocardiogram(ECG)is a crucial tool in the diagnosis and risk stratification of acute coronary syndrome(ACS).Unlike other 11 leads,lead aVR has been long neglected until recent years.However,recent inv...The 12-lead electrocardiogram(ECG)is a crucial tool in the diagnosis and risk stratification of acute coronary syndrome(ACS).Unlike other 11 leads,lead aVR has been long neglected until recent years.However,recent investigations have shown that an analysis of ST-segment shift in lead aVR provides useful information on the coronary angiographic anatomy and risk stratification in ACS.ST-segment elevation in lead aVR can be caused by(1)transmural ischemia in the basal part of the interventricular septum caused by impaired coronary blood flow of the first major branch originating from the left anterior descending coronary artery;(2)transmural ischemia in the right ventricular outflow tract caused by impaired coronary blood flow of the large conal branch originating from the right coronary artery;and(3)reciprocal changes opposite to ischemic or non-ischemic ST-segment depression in the lateral limb and precordial leads.On the other hand,ST-segment depression in lead aVR can be caused by transmural ischemia in the inferolateral and apical regions.It has been recently shown that an analysis of T wave in lead aVR also provides useful prognostic information in the general population and patients with prior myocardial infarction.Cardiologists should pay more attention to the tracing of lead aVR when interpreting the12-lead ECG in clinical practice.展开更多
严重的冠脉病变包括冠脉左主干(left main coronary artery,LMCA)急性完全闭塞、次全闭塞以及3支血管病变(3-vessel disease,3-vd)。尽管LMCA急性完全闭塞患者能生存到达医院者很少,但aVR导联ST段抬高对其诊断的特异性和准确率均超过80...严重的冠脉病变包括冠脉左主干(left main coronary artery,LMCA)急性完全闭塞、次全闭塞以及3支血管病变(3-vessel disease,3-vd)。尽管LMCA急性完全闭塞患者能生存到达医院者很少,但aVR导联ST段抬高对其诊断的特异性和准确率均超过80%。对LMCA急性次全闭塞及3-vd患者,aVR导联ST段抬高的诊断价值高于心电图的任何其他单一或多个导联。aVR导联ST段抬高幅度越大、持续时间越长,患者的病情就越重。本文对aVR导联ST段抬高的诊断标准、电生理机制及国外研究进展进行综述。展开更多
文摘The 12-lead electrocardiogram(ECG)is a crucial tool in the diagnosis and risk stratification of acute coronary syndrome(ACS).Unlike other 11 leads,lead aVR has been long neglected until recent years.However,recent investigations have shown that an analysis of ST-segment shift in lead aVR provides useful information on the coronary angiographic anatomy and risk stratification in ACS.ST-segment elevation in lead aVR can be caused by(1)transmural ischemia in the basal part of the interventricular septum caused by impaired coronary blood flow of the first major branch originating from the left anterior descending coronary artery;(2)transmural ischemia in the right ventricular outflow tract caused by impaired coronary blood flow of the large conal branch originating from the right coronary artery;and(3)reciprocal changes opposite to ischemic or non-ischemic ST-segment depression in the lateral limb and precordial leads.On the other hand,ST-segment depression in lead aVR can be caused by transmural ischemia in the inferolateral and apical regions.It has been recently shown that an analysis of T wave in lead aVR also provides useful prognostic information in the general population and patients with prior myocardial infarction.Cardiologists should pay more attention to the tracing of lead aVR when interpreting the12-lead ECG in clinical practice.
文摘严重的冠脉病变包括冠脉左主干(left main coronary artery,LMCA)急性完全闭塞、次全闭塞以及3支血管病变(3-vessel disease,3-vd)。尽管LMCA急性完全闭塞患者能生存到达医院者很少,但aVR导联ST段抬高对其诊断的特异性和准确率均超过80%。对LMCA急性次全闭塞及3-vd患者,aVR导联ST段抬高的诊断价值高于心电图的任何其他单一或多个导联。aVR导联ST段抬高幅度越大、持续时间越长,患者的病情就越重。本文对aVR导联ST段抬高的诊断标准、电生理机制及国外研究进展进行综述。
