目的通过记录下颌偏斜患者的髁突运动轨迹,研究此类患者髁突运动的规律。方法下颌偏斜患者31例(男性9例,女性22例),年龄12～26岁,平均18岁。使用 CADIAX Ⅲ型髁突运动轨迹轴图描计仪,记录并通过配对 t 检验和秩和检验分析患者下颌侧方...目的通过记录下颌偏斜患者的髁突运动轨迹,研究此类患者髁突运动的规律。方法下颌偏斜患者31例(男性9例,女性22例),年龄12～26岁,平均18岁。使用 CADIAX Ⅲ型髁突运动轨迹轴图描计仪,记录并通过配对 t 检验和秩和检验分析患者下颌侧方运动时髁突的运动轨迹,并将其与患者下颌偏斜量进行多元线性回归分析。结果下颌偏斜患者下颌侧方运动时髁突的运动轨迹不对称,偏斜侧的运动位移大于非偏斜侧,差异有统计学意义(P<0.01);偏斜侧髁突的水平倾斜度小于非偏斜侧,差异有统计意义(P<0.01)。随着偏斜量的增加,偏斜侧与非偏斜侧髁突的位移差距也相应增加,非偏斜侧髁突的位移相应减小,差异有统计学意义(P<0.05)。结论下颌偏斜患者不仅颅面形态不对称,下颌侧方运动时髁突运动轨迹在长度、角度等方面也不对称,其与偏斜量有一定的相关性。展开更多
Nowadays mandibular advancement appliances (MA- As) are available and distributed widely in the field of dentistry for the treatment of snoring and ob- structtive sleep apnea (OSA). However, a few stud- ies discussed ...Nowadays mandibular advancement appliances (MA- As) are available and distributed widely in the field of dentistry for the treatment of snoring and ob- structtive sleep apnea (OSA). However, a few stud- ies discussed temporomandibular joint (TMJ) discom- fort and masticatory muscle stiffness during wearing MAAs are found. A new appliance that we introduced in this pilot study has shown significant jaw move- ment and could diminish TMJ and masticatory side effects.展开更多
The organization of the emotion-related somatic motor behavior, including jaw movements, is governed not only by the cortical limbic system but also by the subcortical limbic system including the amygdala and hypothal...The organization of the emotion-related somatic motor behavior, including jaw movements, is governed not only by the cortical limbic system but also by the subcortical limbic system including the amygdala and hypothalamus. GABAergic neurons in the central amygdaloid nucleus (CeA) and glutamatergic neurons in the posterior lateral hypothalamus (PLH) exert inhibitory and excitatory influences, respectively, upon premotor neurons for the motor trigeminal nucleus (Vm) in the parvicellular reticular formation (RFp) of the medulla oblongata. The CeA also has an inhibitory influence on non-dopaminergic (probably GABAergic) neurons in the retrorubral field of the midbrain that send their axons to the RFp. Furthermore, the CeA and lateral hypothalamus including the PLH may also modulate Vm neurons via projections to the mesencephalic trigeminal nucleus which contains the cell bodies of primary afferent neurons conveying inputs from the masticatory muscle spindles or the periodontal ligament receptors to jaw closing motoneurons within the Vm. These pathways from the subcortical limbic structures to the trigeminal motor system in the lower brainstem underlie the regulation of emotional jaw movements.展开更多
Background: Recording jaw movement rhythms in patients with jaw defects is challenging using conventional tracking devices. However, masticatory rhythm is crucial for masticatory performance and nutritional intake. Th...Background: Recording jaw movement rhythms in patients with jaw defects is challenging using conventional tracking devices. However, masticatory rhythm is crucial for masticatory performance and nutritional intake. This study aimed to explore the impact of using a maxillofacial prosthesis to restore masticatory rhythm in mandibulectomy patients with a novel wearable device. Methods: Twelve patients who underwent mandibulectomy and were rehabilitated with maxillofacial prosthesis were recruited. Chewing rate, cycle durations, coefficient of variation of cycle durations (CV), changing times of skin morphology on the back of the ear pinna area (SM), and masticatory performance were measured during gum chewing without and with a denture using a wearable jaw movement rhythm tracking device. A paired t-test and the Pearson correlation coefficient were used for statistical analysis. Results: The chewing rate increased by 8.6 cycles/min with dentures (P P = 0.01). The CV and SM decreased with dentures (P = 0.004 and P = 0.01, respectively). Significant correlations were found between the CV and SM without dentures (P = 0.004). Conclusion: 1. Wearing maxillofacial prostheses can improve masticatory rhythm in patients who undergo mandibulectomy with Eichner B2 occlusal supports. 2. The wearable device is available for measuring masticatory rhythm in patients with jaw defects in clinics. 3. Changing times of the skin morphology on the back of the ear pinna indicate jaw movement stability through a simpler process than the coefficient of variation of cycle durations.展开更多
磁场是一种安全、无创的物理治疗方法。大量研究证实磁场具有良好的成骨效应,在加速正畸牙移动、促进种植体骨整合、促进骨折愈合和提高牵张成骨效果等方面有一定的临床应用价值,有望成为治疗口腔疾病的一种有效辅助手段。为更好地将磁...磁场是一种安全、无创的物理治疗方法。大量研究证实磁场具有良好的成骨效应,在加速正畸牙移动、促进种植体骨整合、促进骨折愈合和提高牵张成骨效果等方面有一定的临床应用价值,有望成为治疗口腔疾病的一种有效辅助手段。为更好地将磁场应用于临床,本文就磁场在口腔领域的应用、对骨组织细胞的生物学效应和磁场调控骨代谢的分子机制三方面进行综述。磁场对骨组织细胞的生物学效应主要体现为促进成骨细胞和间充质干细胞的成骨,降低骨细胞的凋亡率,对破骨细胞的影响则尚无定论。在分子层面,骨组织细胞感应并响应磁刺激,磁信号经位移电流、洛伦磁力和自由基对效应等机制转变为生物可识别的电信号,进而激活下游P2嘌呤能受体、腺苷受体信号通路、转化生长因子-β受体信号通路、哺乳动物雷帕霉素靶蛋白(mammalian target of rapamycin,m TOR)和Notch通路等信号网络。此外,本文还探讨了影响磁场成骨效应的因素——磁场参数,以期为临床医生提供参考。然而,磁场成骨效应的作用机制目前尚未明确,继续深入研究磁场的作用机制可为骨组织再生和牙周组织再生提供有效策略。另外,聚焦磁场的作用靶点,将磁场与其他药物联合应用,可为口腔疾病的治疗提供新思路。展开更多
文摘目的通过记录下颌偏斜患者的髁突运动轨迹,研究此类患者髁突运动的规律。方法下颌偏斜患者31例(男性9例,女性22例),年龄12～26岁,平均18岁。使用 CADIAX Ⅲ型髁突运动轨迹轴图描计仪,记录并通过配对 t 检验和秩和检验分析患者下颌侧方运动时髁突的运动轨迹,并将其与患者下颌偏斜量进行多元线性回归分析。结果下颌偏斜患者下颌侧方运动时髁突的运动轨迹不对称,偏斜侧的运动位移大于非偏斜侧,差异有统计学意义(P<0.01);偏斜侧髁突的水平倾斜度小于非偏斜侧,差异有统计意义(P<0.01)。随着偏斜量的增加,偏斜侧与非偏斜侧髁突的位移差距也相应增加,非偏斜侧髁突的位移相应减小,差异有统计学意义(P<0.05)。结论下颌偏斜患者不仅颅面形态不对称,下颌侧方运动时髁突运动轨迹在长度、角度等方面也不对称,其与偏斜量有一定的相关性。
文摘Nowadays mandibular advancement appliances (MA- As) are available and distributed widely in the field of dentistry for the treatment of snoring and ob- structtive sleep apnea (OSA). However, a few stud- ies discussed temporomandibular joint (TMJ) discom- fort and masticatory muscle stiffness during wearing MAAs are found. A new appliance that we introduced in this pilot study has shown significant jaw move- ment and could diminish TMJ and masticatory side effects.
文摘The organization of the emotion-related somatic motor behavior, including jaw movements, is governed not only by the cortical limbic system but also by the subcortical limbic system including the amygdala and hypothalamus. GABAergic neurons in the central amygdaloid nucleus (CeA) and glutamatergic neurons in the posterior lateral hypothalamus (PLH) exert inhibitory and excitatory influences, respectively, upon premotor neurons for the motor trigeminal nucleus (Vm) in the parvicellular reticular formation (RFp) of the medulla oblongata. The CeA also has an inhibitory influence on non-dopaminergic (probably GABAergic) neurons in the retrorubral field of the midbrain that send their axons to the RFp. Furthermore, the CeA and lateral hypothalamus including the PLH may also modulate Vm neurons via projections to the mesencephalic trigeminal nucleus which contains the cell bodies of primary afferent neurons conveying inputs from the masticatory muscle spindles or the periodontal ligament receptors to jaw closing motoneurons within the Vm. These pathways from the subcortical limbic structures to the trigeminal motor system in the lower brainstem underlie the regulation of emotional jaw movements.
文摘Background: Recording jaw movement rhythms in patients with jaw defects is challenging using conventional tracking devices. However, masticatory rhythm is crucial for masticatory performance and nutritional intake. This study aimed to explore the impact of using a maxillofacial prosthesis to restore masticatory rhythm in mandibulectomy patients with a novel wearable device. Methods: Twelve patients who underwent mandibulectomy and were rehabilitated with maxillofacial prosthesis were recruited. Chewing rate, cycle durations, coefficient of variation of cycle durations (CV), changing times of skin morphology on the back of the ear pinna area (SM), and masticatory performance were measured during gum chewing without and with a denture using a wearable jaw movement rhythm tracking device. A paired t-test and the Pearson correlation coefficient were used for statistical analysis. Results: The chewing rate increased by 8.6 cycles/min with dentures (P P = 0.01). The CV and SM decreased with dentures (P = 0.004 and P = 0.01, respectively). Significant correlations were found between the CV and SM without dentures (P = 0.004). Conclusion: 1. Wearing maxillofacial prostheses can improve masticatory rhythm in patients who undergo mandibulectomy with Eichner B2 occlusal supports. 2. The wearable device is available for measuring masticatory rhythm in patients with jaw defects in clinics. 3. Changing times of the skin morphology on the back of the ear pinna indicate jaw movement stability through a simpler process than the coefficient of variation of cycle durations.
文摘磁场是一种安全、无创的物理治疗方法。大量研究证实磁场具有良好的成骨效应,在加速正畸牙移动、促进种植体骨整合、促进骨折愈合和提高牵张成骨效果等方面有一定的临床应用价值,有望成为治疗口腔疾病的一种有效辅助手段。为更好地将磁场应用于临床,本文就磁场在口腔领域的应用、对骨组织细胞的生物学效应和磁场调控骨代谢的分子机制三方面进行综述。磁场对骨组织细胞的生物学效应主要体现为促进成骨细胞和间充质干细胞的成骨,降低骨细胞的凋亡率,对破骨细胞的影响则尚无定论。在分子层面,骨组织细胞感应并响应磁刺激,磁信号经位移电流、洛伦磁力和自由基对效应等机制转变为生物可识别的电信号,进而激活下游P2嘌呤能受体、腺苷受体信号通路、转化生长因子-β受体信号通路、哺乳动物雷帕霉素靶蛋白(mammalian target of rapamycin,m TOR)和Notch通路等信号网络。此外,本文还探讨了影响磁场成骨效应的因素——磁场参数,以期为临床医生提供参考。然而,磁场成骨效应的作用机制目前尚未明确,继续深入研究磁场的作用机制可为骨组织再生和牙周组织再生提供有效策略。另外,聚焦磁场的作用靶点,将磁场与其他药物联合应用,可为口腔疾病的治疗提供新思路。
