Objective： To observe different efficacies of low-frequency electroacupuncture（EA） on pancreatic endocrine system in male and female patients with simple obesity due to spleen deficiency-related dampness. Methods：...Objective： To observe different efficacies of low-frequency electroacupuncture（EA） on pancreatic endocrine system in male and female patients with simple obesity due to spleen deficiency-related dampness. Methods： A total of 80 simple obesity patients were assigned to a male group（n=37） and a female group（n=43）. Both groups received a 30-minute low-frequency EA at Yinlingquan（SP 9）, Sanyinjiao（SP 6）, Zusanli（ST 36）, Fenglong（ST 40）, Quchi（LI 11）, Tianshu（ST 25）, Zhongwan（CV 12）, Shuifen（CV 9）, Qihai（CV 6） and Guanyuan（CV 4）. The treatment was done once a day, and 10 times made up a course of treatment. Patients in both groups were treated for 2 courses. Then the changes in body mass index（BMI）, serum insulin, insulin antibodies and leptin level in the two groups were observed and analyzed. Results： After treatment, the BMI, serum insulin, insulin antibodies and leptin levels were significantly reduced in both groups（P〈0.01 or P〈0.05）; the BMI and serum insulin concentration were more significantly reduced in the male group than those in the female group（both P〈0.01）; and the leptin level was more significantly reduced in the female group than that in the male group（P〈0.01）. Conclusion： EA can significantly regulate BMI and pancreatic endocrine system in both men and women with simple obesity; however, there is a gender difference： better effect for men in reducing BMI and serum insulin and better effect for women in reducing serum leptin level.展开更多
目的探讨空腹胰岛素水平对于散发高尿酸血症病人痛风发作的预测价值。方法选择2016年6月—2017年8月我院入院的高尿酸血症痛风病人78例(痛风组)和高尿酸血症无痛风病人120例(高尿酸组)。检测两组病人静脉血中胰岛素、尿酸、糖化血红蛋...目的探讨空腹胰岛素水平对于散发高尿酸血症病人痛风发作的预测价值。方法选择2016年6月—2017年8月我院入院的高尿酸血症痛风病人78例(痛风组)和高尿酸血症无痛风病人120例(高尿酸组)。检测两组病人静脉血中胰岛素、尿酸、糖化血红蛋白、谷丙转氨酶/谷草转氨酶、三酰甘油、总胆固醇、高密度脂蛋白、低密度脂蛋白、游离脂肪酸的水平。Logistic回归分析空腹胰岛素水平与痛风发作的关系,ROC曲线分析空腹胰岛素并预测痛风发作的切点。结果经过筛选,有2个因素与痛风发作相关。Logistic回归分析显示,空腹高胰岛素水平是痛风发作的危险因素(OR=1.091,95%CI=1.032~1.155),HDL水平增高是痛风发作的保护因素(OR=0.082,95%CI=0.026~0.263)。ROC曲线分析空腹胰岛素水平预测痛风发作的最佳切点为10.618 m U/L(诊断特异度为65.5%,灵敏度为80.0%,95%CI=0.715~0.865)。结论空腹高胰岛素水平是痛风发作的危险因素,HDL水平增高是痛风发作的保护性因素,空腹胰岛素预测痛风发作的最佳切点为10.618 m U/L。展开更多
基金supported by Science and Technology Support Project of Hebei Provincial Administration of Traditional Chinese Medicine,No.2014015,No.2017004Youth Fund Project of Hebei University of Chinese Medicine,No.QNZ2014023+1 种基金Science and Technology Plan Project of Hebei Provincial Department of Science and Technology,No.16277704DScience and Technology Research Project of Universities in Hebei Province,No.QN2015139~~
文摘Objective： To observe different efficacies of low-frequency electroacupuncture（EA） on pancreatic endocrine system in male and female patients with simple obesity due to spleen deficiency-related dampness. Methods： A total of 80 simple obesity patients were assigned to a male group（n=37） and a female group（n=43）. Both groups received a 30-minute low-frequency EA at Yinlingquan（SP 9）, Sanyinjiao（SP 6）, Zusanli（ST 36）, Fenglong（ST 40）, Quchi（LI 11）, Tianshu（ST 25）, Zhongwan（CV 12）, Shuifen（CV 9）, Qihai（CV 6） and Guanyuan（CV 4）. The treatment was done once a day, and 10 times made up a course of treatment. Patients in both groups were treated for 2 courses. Then the changes in body mass index（BMI）, serum insulin, insulin antibodies and leptin level in the two groups were observed and analyzed. Results： After treatment, the BMI, serum insulin, insulin antibodies and leptin levels were significantly reduced in both groups（P〈0.01 or P〈0.05）; the BMI and serum insulin concentration were more significantly reduced in the male group than those in the female group（both P〈0.01）; and the leptin level was more significantly reduced in the female group than that in the male group（P〈0.01）. Conclusion： EA can significantly regulate BMI and pancreatic endocrine system in both men and women with simple obesity; however, there is a gender difference： better effect for men in reducing BMI and serum insulin and better effect for women in reducing serum leptin level.
文摘目的探讨空腹胰岛素水平对于散发高尿酸血症病人痛风发作的预测价值。方法选择2016年6月—2017年8月我院入院的高尿酸血症痛风病人78例(痛风组)和高尿酸血症无痛风病人120例(高尿酸组)。检测两组病人静脉血中胰岛素、尿酸、糖化血红蛋白、谷丙转氨酶/谷草转氨酶、三酰甘油、总胆固醇、高密度脂蛋白、低密度脂蛋白、游离脂肪酸的水平。Logistic回归分析空腹胰岛素水平与痛风发作的关系,ROC曲线分析空腹胰岛素并预测痛风发作的切点。结果经过筛选,有2个因素与痛风发作相关。Logistic回归分析显示,空腹高胰岛素水平是痛风发作的危险因素(OR=1.091,95%CI=1.032~1.155),HDL水平增高是痛风发作的保护因素(OR=0.082,95%CI=0.026~0.263)。ROC曲线分析空腹胰岛素水平预测痛风发作的最佳切点为10.618 m U/L(诊断特异度为65.5%,灵敏度为80.0%,95%CI=0.715~0.865)。结论空腹高胰岛素水平是痛风发作的危险因素,HDL水平增高是痛风发作的保护性因素,空腹胰岛素预测痛风发作的最佳切点为10.618 m U/L。
