I.INTRODUCTION Cell proliferation and differentiation are modulated by various regulators. It is well documented that loss control of any one of the key steps in the regulation of normal cell proliferation would cause...I.INTRODUCTION Cell proliferation and differentiation are modulated by various regulators. It is well documented that loss control of any one of the key steps in the regulation of normal cell proliferation would cause abnormal cell growth even result in malignant transformation.Currently, besides the well-known growth factor which is of positive regulation for cell proliferation, growth inhibitors with negative effect on cell growth are also isolated from vari-展开更多
文摘I.INTRODUCTION Cell proliferation and differentiation are modulated by various regulators. It is well documented that loss control of any one of the key steps in the regulation of normal cell proliferation would cause abnormal cell growth even result in malignant transformation.Currently, besides the well-known growth factor which is of positive regulation for cell proliferation, growth inhibitors with negative effect on cell growth are also isolated from vari-
