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镉在土壤-植物-人体系统中迁移积累及其影响因子 被引量:117
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作者 崔玉静 赵中秋 +2 位作者 刘文菊 陈世宝 朱永官 《生态学报》 CAS CSCD 北大核心 2003年第10期2133-2143,共11页
环境镉 (Cd)污染对微生物、植物、动物和人体均可产生较大的危害。食物链是镉对普通人群造成健康危害的主要途径之一。污染土壤中的 1镉通过植物根系吸收与体内转运最终在植物可食部分中积累。Cd通过食物链进入人体并在体内蓄积受许多... 环境镉 (Cd)污染对微生物、植物、动物和人体均可产生较大的危害。食物链是镉对普通人群造成健康危害的主要途径之一。污染土壤中的 1镉通过植物根系吸收与体内转运最终在植物可食部分中积累。Cd通过食物链进入人体并在体内蓄积受许多因素的影响 ,这些影响因素主要有 3个方面 :土壤性质 (土壤含镉量、p H、有机质、粘土矿物和土壤养分状况 ) ,植物特性 (包括基因型差异、根际过程和植物生理机制 )和人体微量元素营养状况等因素。 展开更多
关键词 食物链 镉(CD) 矿物质 影响因子
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人类活动对南极陆地生态系统的影响 被引量:19
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作者 陈杰 Hans-Peter Blume 《极地研究》 CAS CSCD 2000年第1期62-74,共13页
由于科学考察活动日益频繁以及旅游业在南极地区的迅速开展 ,人类活动对南极陆地生态系统的影响在最近几十年内一直倍受国际社会的关注。在广泛收集国外有关资料的基础上 ,本文对人类活动引发的南极地区区域性的土壤与植被污染、野生动... 由于科学考察活动日益频繁以及旅游业在南极地区的迅速开展 ,人类活动对南极陆地生态系统的影响在最近几十年内一直倍受国际社会的关注。在广泛收集国外有关资料的基础上 ,本文对人类活动引发的南极地区区域性的土壤与植被污染、野生动物受扰、外来物种引进、以及细菌性疾病侵入等方面进行了论述。同时 ,阐述了南极以外地区的人为污染源对南极环境的潜在威胁。最后 ,对“南极条约体系”与国际社会为保护南极环境所作出的不懈努力进行了简要介绍与评价。 展开更多
关键词 人类活动 陆地生态系统 污染 南极条约 南极
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南四湖及主要入湖河流沉积物金属空间分布特征与污染评价 被引量:19
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作者 孟祥华 刘恩峰 +2 位作者 杨丽原 孙娟 袁和忠 《环境科学研究》 EI CAS CSCD 北大核心 2010年第1期1-6,共6页
对南四湖湖区及其主要人湖河流表层沉积物中金属元素质量分数进行了测试分析.结果表明,14种金属元素可分为3类组合:Ca和Sr为第1组元素;Al,Fe,Na,K,Mg,Ni,V和Ti为第Ⅱ组元素;第Ⅲ组元素包括Zn,Cr,Cu和Pb.其中,第1组元素... 对南四湖湖区及其主要人湖河流表层沉积物中金属元素质量分数进行了测试分析.结果表明,14种金属元素可分为3类组合:Ca和Sr为第1组元素;Al,Fe,Na,K,Mg,Ni,V和Ti为第Ⅱ组元素;第Ⅲ组元素包括Zn,Cr,Cu和Pb.其中,第1组元素在独山湖区及微山湖区质量分数较高,与第Ⅱ组元素变化趋势相反,这2组元素主要为流域自然来源;第Ⅲ组元素在老运河、白马河上游、洗府河下游及人湖口沉积物中质量分数较高,可能受到人为污染的影响.此外,其他表层沉积物中第Ⅱ组元素与第Ⅲ组元素质量分数具有相似的变化规律.选取流域非耕作土壤样品作为背景,采用参比元素校正及沉积物富集系数法,对Zn,Cr,Cu和Pb等重金属元素的人为污染特征进行了定量评价.结果显示:老运河沉积物中Cr和Pb的富集系数为3.7和3.9,具有中等程度的人为污染特征.Cu和Zn的富集系数达到16.6和22.0,具备重或严重的人为污染特征.Zn和Cu在洗府河下游及入湖口、白马河上游沉积物中的富集系数为2.0~7.1,具有中等或较重的人为污染特征.其余表层沉积物中Zn,Cr,Cu和Pb的富集系数均低于2.0,基本未受到人为污染的影响. 展开更多
关键词 沉积物 金属元素 空间分布 人为污染 南四湖
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Historical trends of heavy metal contamination and their sources in lacustrine sediment from Xijiu Lake,Taihu Lake Catchment,China 被引量:18
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作者 Haijian Bing Yanhong Wu +1 位作者 Zhaobin Sun Shuchun Yao 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2011年第10期1671-1678,共8页
Concentrations of Cd, Cr, Cu, Pb, Zn and Hg in Xijiu Lake sediment from the Taihu Lake catchment, China, were analyzed. Their contamination state was investigated based on the geoaccumulation index and enrichment fact... Concentrations of Cd, Cr, Cu, Pb, Zn and Hg in Xijiu Lake sediment from the Taihu Lake catchment, China, were analyzed. Their contamination state was investigated based on the geoaccumulation index and enrichment factors. Statistical analysis was used to differentiate the anthropogenic versus natural sources of heavy metals (HMs), and the anthropogenic accumulation fluxes were calculated to quantify anthropogenic contribution to HMs. The results indicated that the lake sediment had been heavily contaminated by Cd, enrichment of Zn and Hg was at a relatively high level, while that of Cu and Pb was in the lower-to-moderate level and Cr was in the low enrichment level. Sources of Cr in the sediment were mainly from natural inputs, while other metals, especially Cd, were predominantly derived from anthropogenic sources. In the past century, anthropogenic accumulation fluxes of Pb, Zn and Hg increased by 0.147.3 mg/(cm2-yr), 2.4-398.1 mg/(cm2.yr), and 3.7-110.3 ng/(m2.yr), respectively, accounting for most inputs of HMs entering the sediment. The contamination state of HMs varied with industrial development of the catchment, which demonstrated that contamination started in the early 20th century, reached the maximal level between the mid-1970s and mid-1990s, and decreased a little after the implementation of constraints on high contamination industries, although the contamination of some HMs, such as Cd, Zn and Hg, is still at high levels. 展开更多
关键词 accumulation fluxes contamination heavy metals human activity sediment Xijiu Lake
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Antibiotic Resistance Genes in the Human-Impacted Environment:A One Health Perspective 被引量:14
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作者 James M. TIEDJE WANG Fang +5 位作者 Celia M. MANAIA Marko VIRTA SHENG Hongjie MA Liping ZHANG Tong Edward TOPP 《Pedosphere》 SCIE CAS CSCD 2019年第3期273-282,共10页
Antibiotic resistance and its environmental component are gaining more attention as part of combating the growing healthcare crisis. The One Health framework, promulgated by many global health agencies, recognizes tha... Antibiotic resistance and its environmental component are gaining more attention as part of combating the growing healthcare crisis. The One Health framework, promulgated by many global health agencies, recognizes that antimicrobial resistance is a truly inter-domain problem in which human health, animal agriculture, and the environment are the core and interrelated components.This prospectus presents the status and issues relevant to the environmental component of antibiotic resistance, namely, the needs for advancing surveillance methodology: the environmental reservoirs and sources of resistance, namely, urban wastewater treatment plants, aquaculture production systems, soil receiving manure and biosolid, and the atmosphere which includes longer range dispersal.Recently, much work has been done describing antibiotic resistance genes in various environments;now quantitative, mechanistic,and hypothesis-driven studies are needed to identify practices that reduce real risks and maintain the effectiveness of our current antibiotics as long as possible. Advanced deployable detection methods for antibiotic resistance in diverse environmental samples are needed in order to provide the surveillance information to identify risks and define barriers that can reduce risks. Also needed are practices that reduce antibiotic use and thereby reduce selection for resistance, as well as practices that limit the dispersal of or destroy antibiotic-resistant bacteria or their resistance genes that are feasible for these varied environmental domains. 展开更多
关键词 animal agriculture antibiotic-resistant bacteria antimicrobial resistance AQUACULTURE human health One Health framework soil contamination wastewater and sludge
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An experimental study of preventing and treating acute radioactive enteritis with human umbilical cord mesenchymal stem cells 被引量:9
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作者 Rui Wang Wei Yuan +4 位作者 Qiang Zhao Peng Song Ji Yue Shi-De Lin Ting-Bao Zhao 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2013年第12期968-971,共4页
Objective:To test the curative effect of human umbilical cord-derived mesenchymal stem cells on rat acute radioactive enteritis and thus in provide clinical therapeutic basis for radiation sickness.Methods:Human umbil... Objective:To test the curative effect of human umbilical cord-derived mesenchymal stem cells on rat acute radioactive enteritis and thus in provide clinical therapeutic basis for radiation sickness.Methods:Human umbilical cord-derived mesenchymal stem cells were cultivated in vitro and the model of acute radioactive enteritis of rats was established.Then,the umbilical cord mesenchymal stem cells were injected into the rats via tail vein.Visual and histopathiological changes of the experimental rats were observed.Results:After the injection,the rats in the prevention group and treatment group had remarkably better survival status than those in the control group.The histological observations revealed that the former also had better intestinal mucosa structure,more regenerative cells and stronger proliferation activity than the latter.Conclusions:Human umbilical cord-derived mesenchymal stem cells have a definite therapeutic effect on acute radioactive enteritis in rats. 展开更多
关键词 RADIOACTIVE contamination human UMBILICAL CORD MESENCHYMAL stem cells ACUTE RADIOACTIVE ENTERITIS Rat
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Changes in hair arsenic concentration in a population exposed to heavy pollution:Follow-up investigation in Chenzhou City,Hunan Province,Southern China 被引量:4
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作者 Bin Wu,Tongbin Chen Center for Environmental Remediation,Institute of Geographic Sciences and Natural Resources Research,Chinese Academy of Sciences,Beijing 100101,China. 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2010年第2期283-289,共7页
Follow-up investigation on hair arsenic concentration was conducted in an arsenic heavily polluted area of southern China in 2002 and 2006. The results showed that the geometric mean of hair arsenic concentration decr... Follow-up investigation on hair arsenic concentration was conducted in an arsenic heavily polluted area of southern China in 2002 and 2006. The results showed that the geometric mean of hair arsenic concentration decreased from 2.95 mg/kg in 2002 to 1.78 mg/kg in 2006, when the percentage of the population with levels over 1 mg/kg only decreased from 93.4% in 2002 to 80.5% in 2006. Over this four-year period, the population with high arsenic concentrations decreased significantly while there was no obvious change in hair arsenic concentration for people who had relatively low concentrations. In terms of age distribution, young and old people had higher hair arsenic concentrations than the middle-aged. All of these results showed that it is difficult to reverse the negative impact of arsenic pollution on human health. Arsenic pollution has a long-term continuous influence on the health of local residents. 展开更多
关键词 ARSENIC human health soil contamination hair arsenic
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广州水体中人类杯状病毒污染状况检测分析 被引量:2
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作者 曾爱华 金小宝 朱家勇 《中国公共卫生》 CAS CSCD 北大核心 2012年第12期1641-1643,共3页
目的调查研究广东省广州地区水体中人类杯状病毒(HuCV)的污染情况。方法收集广州地区268份自来水、715份矿泉水、119份生活污水和53份池塘水,用荧光定量PCR方法检测样本中的HuCV及GⅠ、GⅡ型的诺瓦克样病毒(NLVs)和扎幌样病毒(SLVs)。... 目的调查研究广东省广州地区水体中人类杯状病毒(HuCV)的污染情况。方法收集广州地区268份自来水、715份矿泉水、119份生活污水和53份池塘水,用荧光定量PCR方法检测样本中的HuCV及GⅠ、GⅡ型的诺瓦克样病毒(NLVs)和扎幌样病毒(SLVs)。结果生活污水、池塘水、自来水、矿泉水中HuCV总检出率分别为9.24%、11.32%、0、0;生活污水中的GⅠ、GⅡ型的NLVs和SLVs检出率分别为2.52%、7.56%和0;池塘水中的GⅠ、GⅡ型的NLVs和SLVs检出率分别为1.89%、9.43%、0、1.89%;在1例生活污水中检测出GⅠ、GⅡ型NLVs,1例池塘水里同时检测出GⅡ型NLVs、SLVs。结论广州地区生活用水是安全的,但环境水体中存在着HuCV不同基因型的混合污染。 展开更多
关键词 人类杯状病毒(HuCV) 基因型 污染
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<i>Aflatoxin</i>M1 (<i>Aspergillus parasiticus, flavus</i>) Occurrences in Milk and Milk Products and Its Possible Health Effects
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作者 Nafisatu Bukari Mabel Kyei Kwofie Oluwaseyi Adeboye 《Advances in Microbiology》 2020年第10期509-524,共16页
<i>Aflatoxin</i> M1 (AFM1) occurrence in milk and milk products has been a major concern among food scientists over the past three decades owing to its possible health risk in humans. The well-documented A... <i>Aflatoxin</i> M1 (AFM1) occurrence in milk and milk products has been a major concern among food scientists over the past three decades owing to its possible health risk in humans. The well-documented AFM1 associated adverse health outcomes include hepatocarcinogens, mutagens genotoxins, mutagenicity, and teratogen. The paper reviews the occurrence of AFM1 in milk, milk products, and human milk in developing and developed countries, with its safety standards of regulation. The health associated risks with AFM1 are the important methods used in detecting and reducing AFM1 in milk and other milk products are presented. 展开更多
关键词 AFLATOXINS MILK Milk Products human Milk contamination Feeds
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Contamination Levels of Some Selected Wells in Ogbomoso South Local Government Area, Nigeria and the Implications on Human Health
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作者 Samson O. Ojoawo T. Lateef Kolade 《Journal of Water Resource and Protection》 2013年第7期653-668,共16页
Incident of water-borne diseases is becoming more rampant in developing countries in the 21st century. This paper examines the contamination levels of some selected wells in Ogbomoso South Local Government Area (LGA),... Incident of water-borne diseases is becoming more rampant in developing countries in the 21st century. This paper examines the contamination levels of some selected wells in Ogbomoso South Local Government Area (LGA), Oyo State, Nigeria. Methodology includes administering of structured questionnaire, field survey/sampling and laboratory analysis. The first set of questionnaires sought information on water sources, quality, supply and treatment. These were administered in 10 selected major locations which included: Ajegunle, Arinkinkin, Arowomole, Caretaker, Esanu-Aje, Ita-Olola, Malete, Oke-Alapata, Ora-Gada and Sunsun. The other set which was administered in 6 randomly selected Health Institutions viz: Oyo State General Hospital, Alaafia Tayo, Oore-Ofe, Bethel, Favour, and Grace Hospitals had questions on health-related issues. Ten (10) wells were randomly selected for sampling, one in each location. Results were compared with WHO’s Drinking Water Standards. Questionnaires revealed that residents depended mostly on wells for water supply;the water quality was low;supply was irregular;quantity was inadequate and boiling was the commonest treatment method. Health Officials established that some residents consumed improperly treated well water and there were some incidences of water-related diseases. Laboratory analyses showed that samples from Ajegumle and Esanu-Aje had colour values above the standard. Also, the pH was observed to vary from slightly acidic to slightly alkaline with values ranging between 6.0 and 8.1. Only Arinkinkin and Ita-Olola areas had permissible values of total alkalinity and Oke-Alapata had the highest chloride value of 400 mg/l while the highest nitrate concentration was at Esanu-Aje (127.58 mg/l). Study concludes that water supply in the area is not fully supportive to health. To abate the problem, it is recommended that aside boiling, each household should endeavour to coagulate, filter, soften and disinfect well water before consumption. Also, personal hygiene within each household m 展开更多
关键词 contamination WELLS Water Quality human Health
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人乳和牛乳中有机物种类及邻苯二甲酸二丁酯水平的比较 被引量:1
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作者 刘慧杰 曹佳 舒为群 《中华预防医学杂志》 CAS CSCD 北大核心 2011年第1期53-56,共4页
目的 比较人乳和牛乳中有机物种类及邻苯二甲酸二丁酯(DBP)的污染水平.方法 选取40名健康产妇,年龄(27.44±3.43)岁.分别采集每名产妇乳汁5 ml.采用简单随机抽样的方法选取市售常见4种不同品牌鲜牛奶和1种品牌的奶粉,每种品牌... 目的 比较人乳和牛乳中有机物种类及邻苯二甲酸二丁酯(DBP)的污染水平.方法 选取40名健康产妇,年龄(27.44±3.43)岁.分别采集每名产妇乳汁5 ml.采用简单随机抽样的方法选取市售常见4种不同品牌鲜牛奶和1种品牌的奶粉,每种品牌的牛奶制品分别抽取3个样品,共取样15份(其中鲜牛奶12份,奶粉3份).应用气相色谱-质谱(GC-MS)联用法分别对样品中有机物种类进行定性分析及DBP的定量测定.结果 在40份人乳中共检出有机物176种,平均(10.58±4.16)种;12份鲜牛奶中共检出有机物37种,平均为(8.67±1.61)种;3份奶粉中共检出有机物31种,平均(12.67±0.58)种.奶粉中的有机物检出种类数高于人乳和鲜牛奶(t值分别为2.09、4.00,P值均〈0.05).在人乳与牛乳中检出率均较高的有机物主要是9-十八烯酸,人乳中检出率为45.00%(18/40),牛乳中检出率为53.33%(8/15).人乳中DBP的含量为(57.78±35.42)μg/L,鲜牛奶中DBP的含量为(20.76±6.60)μg/L,奶粉中DBP的含量为(0.45±0.05)mg/kg[相当于浓度值为(66.78±7.60)μg/L].鲜牛奶中DBP含量低于人乳和奶粉(t值分别为37.02、46.02,P值均〈0.05).结论 人乳与牛乳中均含有多种环境有机污染物,部分污染物具有生殖和发育毒性. 展开更多
关键词 食品污染 邻苯二甲酸二丁酯
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长江南京段表层水体中12种磺胺类抗生素的污染水平及风险评价 被引量:27
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作者 唐娜 张圣虎 +3 位作者 陈玫宏 宋宁慧 徐怀洲 张芹 《环境化学》 CAS CSCD 北大核心 2018年第3期505-512,共8页
为评价长江南京段表层水体磺胺类抗生素的污染水平、生态风险及健康风险,利用高效液相色谱-串联质谱测定了长江南京段水体中14个采样点的12种磺胺类化合物.结果显示,长江南京段表层水体中共检出了8种磺胺类化合物,总浓度范围为13.2—21.... 为评价长江南京段表层水体磺胺类抗生素的污染水平、生态风险及健康风险,利用高效液相色谱-串联质谱测定了长江南京段水体中14个采样点的12种磺胺类化合物.结果显示,长江南京段表层水体中共检出了8种磺胺类化合物,总浓度范围为13.2—21.0 ng·L^(-1),中值为16.4 ng·L^(-1),平均值为16.2 ng·L^(-1),8种检出抗生素中最高的为磺胺甲唑,浓度范围为6.76—8.98 ng·L^(-1),其次是为磺胺嘧啶,浓度范围为2.52—6.59 ng·L^(-1).其中磺胺甲噻二唑、磺胺间甲氧嘧啶、磺胺甲氧哒嗪及磺胺噻唑在所有采样点均未检出.总体来说,长江南京段水体中的磺胺类抗生素浓度与国内及国外其他水体包括河流湖泊相比处于相对较低的水平.对4种磺胺类抗生素的生态风险评价结果表明,所有的4种抗生素RQs均小于0.01.采用简单叠加模型计算的磺胺类抗生素的联合毒性风险熵范围为0.0029—0.0039,表明长江南京段磺胺类抗生素对于水生生物风险不显著.对4种磺胺类抗生素的人体健康风险评价结果表明,每种化合物对于每个年龄段的RQs均小于1,表明长江南京段表层水体中的磺胺类抗生素对人体健康无风险. 展开更多
关键词 抗生素 长江南京段 地表水 生态风险评估 健康风险评估 污染 磺胺类
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无菌制剂车间环境微生物污染情况监测 被引量:6
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作者 张文婷 刘绪平 熊骏 《药物分析杂志》 CAS CSCD 北大核心 2019年第10期1895-1901,共7页
目的:采集无菌制剂生产车间洁净区环境微生物,应用全自动微生物检测系统进行监测分析,并进行耐药分析。方法:采样方法有沉降菌法、定量空气浮游菌采样法和表面取样法,对采集到的沉降菌、浮游菌、人员及设备表面微生物按照菌种鉴定仪使... 目的:采集无菌制剂生产车间洁净区环境微生物,应用全自动微生物检测系统进行监测分析,并进行耐药分析。方法:采样方法有沉降菌法、定量空气浮游菌采样法和表面取样法,对采集到的沉降菌、浮游菌、人员及设备表面微生物按照菌种鉴定仪使用说明书操作进行菌种鉴定和耐药性检测。结果:从345个样本中,检出微生物115株,其中沉降菌105株,浮游菌6株,人员及表面微生物4株;115株菌鉴定为46个菌种,分属于20个菌属。可信限均在95%以上。其中还检出了3株耐药菌。结论:对无菌GMP车间环境微生物进行监测,并建立药品GMP生产企业微生物信息库,可以更好地指导药品GMP企业实现有效的微生物管理。 展开更多
关键词 沉降菌 浮游菌 表面微生物 洁净区 微生物污染 溯源分析
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人来源样品中铝、砷、铬、镉和汞微量元素检测分析前因素的质量控制 被引量:5
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作者 钟堃 王薇 +2 位作者 何法霖 袁帅 王治国 《现代检验医学杂志》 CAS 2017年第2期160-164,共5页
该文旨在规范人来源样品中铝、砷、铬、镉和汞微量元素检测的分析前因素的质量控制,减少分析前变异对检测结果的影响。根据美国临床实验室标准化委员会(clinical and laboratory standards institute,CLSI)的批准指南,检测分析前变异的... 该文旨在规范人来源样品中铝、砷、铬、镉和汞微量元素检测的分析前因素的质量控制,减少分析前变异对检测结果的影响。根据美国临床实验室标准化委员会(clinical and laboratory standards institute,CLSI)的批准指南,检测分析前变异的控制和相关文献来制定人来源样品铝、砷、铬、镉和汞检测的质量控制方案,包括:人来源样品的采集、运输和处理所需考虑的因素,患者的准备,样品采集、运输、接收、保存和处理等方面实验室工作人员所需准备的条件,污染控制和质量保证计划等。通过查阅相关的指南和文献,对人来源样品检测的分析前因素,包括污染的预防控制、样品的选择与采集的操作规程等进行了较为详细和系统的描述和说明,希望能为人来源样品检测的实验室工作人员提供建议和帮助。 展开更多
关键词 人来源样品 分析前因素 污染控制
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STR图谱分析法鉴别人源细胞交叉污染 被引量:5
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作者 吴瑜 冯建平 +4 位作者 林林 吴雪伶 孟淑芳 王佑春 李德富 《中国生物制品学杂志》 CAS CSCD 2010年第1期74-78,86,共6页
目的采用STR图谱分析法鉴别人源细胞交叉污染。方法采用PCR-毛细管电泳分析方法,分别检测人源、猴源及鼠源细胞以及人源细胞交叉污染模型的16个STR位点,分析STR图谱法用于细胞交叉污染检测的可行性。并对来自不同生物制品生产单位的27... 目的采用STR图谱分析法鉴别人源细胞交叉污染。方法采用PCR-毛细管电泳分析方法,分别检测人源、猴源及鼠源细胞以及人源细胞交叉污染模型的16个STR位点,分析STR图谱法用于细胞交叉污染检测的可行性。并对来自不同生物制品生产单位的27株生产用细胞及5株组织工程医疗产品用细胞进行STR图谱分析。结果STR图谱分析方法具有人源细胞特异性,猴源细胞及鼠源细胞不产生特征性图谱。此方法可以对形态相似或不相似的人源细胞交叉污染模型进行明确鉴别。采用此方法检测的27株生物制品生产用人源细胞未发现有交叉污染现象,而5株组织工程医疗产品用细胞中,发现有2株为非单个个体的混合细胞。结论STR图谱分析法具有高特异性,可用于人源细胞间交叉污染或细胞个体来源的鉴别。 展开更多
关键词 STR图谱 人源细胞 组织工程产品 交叉污染
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载人火星探测的行星保护 被引量:3
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作者 徐侃彦 马玲玲 +2 位作者 印红 张秦 邹乐洋 《深空探测学报》 2019年第1期23-30,共8页
行星保护是影响载人火星探索任务的重要问题之一。载人探测的行星保护包括3个方面,即防止来源于地球的微生物污染目标星球的正向污染防护、防止外来生物对地球的潜在危害的逆向污染防护,以及确保航天员的健康和安全。国际宇航界已经开... 行星保护是影响载人火星探索任务的重要问题之一。载人探测的行星保护包括3个方面,即防止来源于地球的微生物污染目标星球的正向污染防护、防止外来生物对地球的潜在危害的逆向污染防护,以及确保航天员的健康和安全。国际宇航界已经开始针对载人火星探测的行星保护制定政策法规和开展技术研讨。本文介绍了行星保护的定义和法理依据,简要回顾了美国国家航空航天局在"阿波罗登月"中的行星保护措施,并对未来载人火星探测中的主要污染物、污染途径以及污染防护策略进行了初步探讨。 展开更多
关键词 行星保护 载人火星探测 正向污染 逆向污染 污染物 污染途径
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54例人肺癌细胞系的交叉污染情况分析
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作者 方未英 刘毅 +2 位作者 徐兰 顾婷玉 陈跃磊 《中国细胞生物学学报》 CAS CSCD 2024年第8期1515-1520,共6页
该研究旨在鉴定国内实验室肺癌细胞系使用的正确性,对从国内多个实验室收集的54例人肺癌细胞样品提取基因组DNA,使用PCR技术扩增短串联重复序列(short tandem repeat,STR)后进行毛细管电泳,获得细胞的STR图谱。与国际数据库中已知细胞系... 该研究旨在鉴定国内实验室肺癌细胞系使用的正确性,对从国内多个实验室收集的54例人肺癌细胞样品提取基因组DNA,使用PCR技术扩增短串联重复序列(short tandem repeat,STR)后进行毛细管电泳,获得细胞的STR图谱。与国际数据库中已知细胞系的STR图谱进行比对,通过计算匹配度确认细胞系的身份信息,判断细胞是否存在交叉污染。结果表明54例肺癌细胞样品中存在交叉污染的有14例,错误率为25.93%(14/54)。其中51例常见人肺癌细胞样品的错误率为27.45%(14/51),3例中国科学院分子细胞科学卓越创新中心/生物化学与细胞生物学研究所科学家建立的人肺癌细胞系样品的错误率为0%(0/3)。该研究针对国内细胞系交叉污染的情况,分析了其原因并提出了相应的建议。 展开更多
关键词 短串联重复序列分型 人肺癌细胞系 交叉污染
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Ecological and Human Health Risk Assessment of Toxic Metals in Water, Sediment and Fish from Lower Usuma Dam, Abuja, Nigeria 被引量:2
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作者 R. Wuana C. Ogbodo +1 位作者 A. U. Itodo I. S. Eneji 《Journal of Geoscience and Environment Protection》 2020年第5期82-106,共25页
The study assessed the levels of some toxic metals (As, Cd, Cr, Cu, Hg, Ni, Pb and Zn) with their potential ecological and human health risks in water, African Catfish (Clarias gariepinus), Tilapia (Oreochromis spilur... The study assessed the levels of some toxic metals (As, Cd, Cr, Cu, Hg, Ni, Pb and Zn) with their potential ecological and human health risks in water, African Catfish (Clarias gariepinus), Tilapia (Oreochromis spilurus niger) and sediment samples from the Lower Usuma dam FCT, Nigeria during two major seasons in a year (rainy and dry seasons). Toxic metal concentrations were determined using Atomic Absorption spectrophotometry (Cd, Cr, Cu, Ni, Pb and Zn) and Atomic Emission Spectrophotometry (for As and Hg), and the results obtained were compared with national and international standards. The ecological and human health risk indices of the toxic metals present in the samples from the Dam were evaluated and interpreted. Tilapia from the dam posed the highest but medium ecological and human health risk due to Pb concentration of up to 7.11 mg/kg;ecological risk index of 35.55 and hazard quotient of 50.78. Overall ecological and human health risks were low due to the low concentrations of other toxic metals determined. As, Cd, Cr, Cu, Hg, Ni and Zn concentrations were all below WHO limits in the LUD water;Ni and Pb were above limits in the African Catfish and Tilapia samples. The data obtained were analyzed using one-way analysis of variance (ANOVA) and significant differences accepted at p ≤ 0.05. There was no statistical difference in the concentrations of toxic metals in water but there was significant difference between the concentrations of toxic metals in the fish and sediment samples. Correlation was found to exist between toxic metals in the water, fish and sediment analyzed from the dam. The ecological and human health risks of toxic metals in Lower Usuma dam require regular checks and monitoring hence, it was recommended by the researcher, that this and similar research work be carried out annually by NESREA and also, as research work by other students of Environmental and Analytical chemistry. 展开更多
关键词 Toxic Metals AAS AES Concentration ECOLOGICAL RISK human Health RISK LOWER Usuma DAM contamination Factor Water SEDIMENT FISH
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The Volatilization of Pollutants from Soil and Groundwater: Its Importance in Assessing Risk for Human Health for a Real Contaminated Site
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作者 Pamela Morra Laura Leonardelli Gigliola Spadoni 《Journal of Environmental Protection》 2011年第9期1192-1206,共15页
Pollution of different elements (air, water, soil and subsoil) resulting both from accidental events and from ordinary industrial and civil activities causes negative effects on the human health and on the environment... Pollution of different elements (air, water, soil and subsoil) resulting both from accidental events and from ordinary industrial and civil activities causes negative effects on the human health and on the environment. The present paper examines the analysis of a contaminated site, focusing the attention on the negative effects for receptors exposed to soil and groundwater contamination caused by industrial activities. The case study investigated is a contaminated area located in the industrial district of Trento North once occupied by the Italian Carbochimica plant. Pollution in that area is mainly due to contamination of soil and groundwater with polycyclic aromatic hydrocarbons. The methodology applied is the risk evaluation for human health, in terms of individual cancer risk and hazard index. In particular the attention has been focused on a specific migration way: if pollutants in the soil or in the groundwater undergo a phase change, they spread and get to the soil surface, causing a dispersion of vapors in the atmosphere. In this case risk assessment calls for the evaluation of volatilization factor. Among the different models dealing with the estimation of volatilization factor, those mostly known and used in the national and international field of Human Health Risk Assessment were chosen: Jury’s and Farmer’s models. A sensitivity analysis of models was performed, in order to identify the most significant parameters to estimate the volatilization factors among the wide range of input parameters for the application of models. Performing an accurate selection and data processing of the contaminated site, models for the volatilization factors calculation are applied, thus evaluating air concentrations and Human Health Risk. The analysis of the resulting estimates is an excellent aid to draw interesting conclusions and to verify if the soil and groundwater pollutants volatilization affects the human health considerably. 展开更多
关键词 human Health RISK Assessment VOLATILIZATION Models SOIL contamination GROUNDWATER contamination Cancer RISK Hazard Index
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消除人血白蛋白制品中热原的工艺实验研究 被引量:3
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作者 王克勤 蔡兴三 严涛世 《中国医院药学杂志》 CAS CSCD 北大核心 1990年第10期437-439,共3页
本文首次系统地报道了消除HSA 制品中污染热原的综合工艺,经十二批热原消除和十一批生产中应用,结果表明:本工艺解决了被热原污染的HSA 制品的去热原纯化问题,纯化后其质可达到合格标准。
关键词 人血白蛋白 细菌内毒素 热原质污染
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