Objective:To study the mental health status of heroin addicts and their need for psychotherapy after detoxification. Methods:The mental health of 83 heroin addicts and 70 normal subjects were assessed by SCL-90, Socia...Objective:To study the mental health status of heroin addicts and their need for psychotherapy after detoxification. Methods:The mental health of 83 heroin addicts and 70 normal subjects were assessed by SCL-90, Social Support Rating Scale , EPQ, SAS and SDS. Results:As compared to normal controls, heroin additions were found to score higher on various mental health measures, including SCL-90 total and factor scores, the N score of EPQ, as well as total scores on SAS and SDS. The social support in heroin addicts scored lower than normal subjects. Conclusion:Heroin addicts have severe psychological problems, which warrant long-term psychological rehabilitation after detoxification.展开更多
Inhibitory control dysfunction is regarded as a core feature in addicts.The major objective of this study was to explore the time course of response inhibition in chronic heroin addicts and provide the neurophysiologi...Inhibitory control dysfunction is regarded as a core feature in addicts.The major objective of this study was to explore the time course of response inhibition in chronic heroin addicts and provide the neurophysiological evidence of their inhibitory control dysfunction.The amplitudes and latencies of ERP components were studied in fourteen heroin addicts(mean duration of heroin use being(13.54±5.71) years(Mean±SD),average abstinence being((4.67±6.44) months)) and fourteen matched healthy controls with a visual Go/Nogo task.Our results showed that heroin addicts demonstrated significantly larger Go-N2 amplitudes which results in a decreased N2 Go/Nogo effect,but no statistically significant differences were found between heroin addicts and controls in P3.The ERP data suggest that fronto-central areas of heroin addicts were impaired during the inhibition process(200-300 ms) and over-activated to targets.The impaired early process might reflect an abnormal conflict monitoring process in heroin addicts.These results consolidate the inhibitory control dysfunction hypothesis in chronic heroin users.展开更多
Objective: To investigate the effect of heroin on memory function in heroin addicts. Methods: Memory function of thirty-six heroin addicts and thirty-six normal controls was assessed with Wechsler Memory scale-Revised...Objective: To investigate the effect of heroin on memory function in heroin addicts. Methods: Memory function of thirty-six heroin addicts and thirty-six normal controls was assessed with Wechsler Memory scale-Revised in China. Results: The memory quotient and the scores on such factors as picture recall, design reproduction, traction memory,story recall as well as digit span of heroin addicts were significant lower than those of control group (P<0.01).The impairment of memory function in heroin addicts was positively correlated with the dosage of heroin and duration of heroin consuming through further analysis. Conclusion: There was impairment of memory function to a greater or lesser degree in heroin addicts.展开更多
文摘Objective:To study the mental health status of heroin addicts and their need for psychotherapy after detoxification. Methods:The mental health of 83 heroin addicts and 70 normal subjects were assessed by SCL-90, Social Support Rating Scale , EPQ, SAS and SDS. Results:As compared to normal controls, heroin additions were found to score higher on various mental health measures, including SCL-90 total and factor scores, the N score of EPQ, as well as total scores on SAS and SDS. The social support in heroin addicts scored lower than normal subjects. Conclusion:Heroin addicts have severe psychological problems, which warrant long-term psychological rehabilitation after detoxification.
基金Supported by Beijing Bureau of Reeducation-through-laber Administration (Grant NO. 2006021515)
文摘Inhibitory control dysfunction is regarded as a core feature in addicts.The major objective of this study was to explore the time course of response inhibition in chronic heroin addicts and provide the neurophysiological evidence of their inhibitory control dysfunction.The amplitudes and latencies of ERP components were studied in fourteen heroin addicts(mean duration of heroin use being(13.54±5.71) years(Mean±SD),average abstinence being((4.67±6.44) months)) and fourteen matched healthy controls with a visual Go/Nogo task.Our results showed that heroin addicts demonstrated significantly larger Go-N2 amplitudes which results in a decreased N2 Go/Nogo effect,but no statistically significant differences were found between heroin addicts and controls in P3.The ERP data suggest that fronto-central areas of heroin addicts were impaired during the inhibition process(200-300 ms) and over-activated to targets.The impaired early process might reflect an abnormal conflict monitoring process in heroin addicts.These results consolidate the inhibitory control dysfunction hypothesis in chronic heroin users.
文摘Objective: To investigate the effect of heroin on memory function in heroin addicts. Methods: Memory function of thirty-six heroin addicts and thirty-six normal controls was assessed with Wechsler Memory scale-Revised in China. Results: The memory quotient and the scores on such factors as picture recall, design reproduction, traction memory,story recall as well as digit span of heroin addicts were significant lower than those of control group (P<0.01).The impairment of memory function in heroin addicts was positively correlated with the dosage of heroin and duration of heroin consuming through further analysis. Conclusion: There was impairment of memory function to a greater or lesser degree in heroin addicts.
