Bayés syndrome is an under-recognized clinical condition characterized by advanced interatrial block.Bayés syndrome is a subclinical disease that manifests electrocardiographically as a prolonged P wave dura...Bayés syndrome is an under-recognized clinical condition characterized by advanced interatrial block.Bayés syndrome is a subclinical disease that manifests electrocardiographically as a prolonged P wave duration>120 ms with biphasic morphology±in the inferior leads.The clinical relevance of Bayés syndrome lies in the fact that is a clear arrhythmological syndrome and has a strong association with supraventricular arrhythmias,particularly atypical atrial flutter and atrial fibrillation.Likewise,Bayés syndrome has been recently identified as a novel risk factor for non-lacunar cardioembolic ischemic stroke and vascular dementia.Advanced interatrial block can be a risk for embolic stroke due to its known sequelae of left atrial dilation,left atrial electromechanical dysfunction or atrial tachyarrhythmia(paroxysmal or persistent atrial fibrillation),conditions predisposing to thromboembolism.Bayés syndrome may be responsible for some of the unexplained ischemic strokes and shall be considered and investigated as a possible cause for cryptogenetic stroke.In summary,Bayés syndrome is a poorly recognized cardiac rhythm disorder with important cardiologic and neurologic implications.展开更多
OBJECTIVE: To precisely visualize cardiac anatomic structures and simultaneously depict electro-mechanical events for the purpose of precise underblood intervention. METHODS: Intracardiac high-resolution tissue Dopple...OBJECTIVE: To precisely visualize cardiac anatomic structures and simultaneously depict electro-mechanical events for the purpose of precise underblood intervention. METHODS: Intracardiac high-resolution tissue Doppler imaging was used to map real time myocardial contractions in response to electrical activation within the anatomic structure of the cardiac conductive system using a canine open-chest model. RESULTS: The detailed inner anatomic structure of the cardiac conductive system at different sites (i.e., sino-atrial, atrial wall, atrial-ventricular node and ventricular wall) with the inside onset and propagation of myocardial velocity and acceleration induced by electrical activation was clearly visualized and quantitatively evaluated. CONCLUSION: The simultaneous single modality visualization of the anatomy, function and electrical events of the cardiac conductive system will foster target pacing and precision ablation.展开更多
目的通过对心肌肥厚兔模型进行电生理研究,探讨心肌肥厚对心传导系统的影响。方法雄性新西兰大耳兔24只,随机分为心肌肥厚组和对照组,每组各12只。经耳缘静脉注射异丙肾上腺素制备心肌肥厚模型。造模2周后行超声检查评价造模结果。对所...目的通过对心肌肥厚兔模型进行电生理研究,探讨心肌肥厚对心传导系统的影响。方法雄性新西兰大耳兔24只,随机分为心肌肥厚组和对照组,每组各12只。经耳缘静脉注射异丙肾上腺素制备心肌肥厚模型。造模2周后行超声检查评价造模结果。对所有动物行在体电生理检查,测量两组动物心房有效不应期(AERP)、房室结有效不应期(AVERP)、房室结反向传导有效不应期(VAERP)、窦房传导时间(SACT)、最大窦房恢复时间(SNRTMAX)、文氏周期长度(WCL),反文氏周期长度(RWCL)、房室2∶1传导频率等指标。结果心肌肥厚组AERP较对照组缩短(68.60±6.20 ms vs 77.30±12.30 ms,P<0.05),SACT、SNRTMAX、AVERP、WCL及房室2:1传导频率较对照组延长(分别为101.57±25.11 ms vs 78.33±25.17 ms,616.91±59.89 ms vs 540.64±83.18 ms,160.30±9.73 ms vs 133.80±3.89 ms,191.40±32.90 ms vs 151.10±24.30 ms,148.8±35.00 ms vs 137.30±23.40 ms,P均<0.05),而VAERP与RWCL较对照组则无明显变化(P>0.05)。结论心肌肥厚可导致心传导系统功能受损,为心肌肥厚时心律失常的发生提供条件。展开更多
文摘Bayés syndrome is an under-recognized clinical condition characterized by advanced interatrial block.Bayés syndrome is a subclinical disease that manifests electrocardiographically as a prolonged P wave duration>120 ms with biphasic morphology±in the inferior leads.The clinical relevance of Bayés syndrome lies in the fact that is a clear arrhythmological syndrome and has a strong association with supraventricular arrhythmias,particularly atypical atrial flutter and atrial fibrillation.Likewise,Bayés syndrome has been recently identified as a novel risk factor for non-lacunar cardioembolic ischemic stroke and vascular dementia.Advanced interatrial block can be a risk for embolic stroke due to its known sequelae of left atrial dilation,left atrial electromechanical dysfunction or atrial tachyarrhythmia(paroxysmal or persistent atrial fibrillation),conditions predisposing to thromboembolism.Bayés syndrome may be responsible for some of the unexplained ischemic strokes and shall be considered and investigated as a possible cause for cryptogenetic stroke.In summary,Bayés syndrome is a poorly recognized cardiac rhythm disorder with important cardiologic and neurologic implications.
文摘OBJECTIVE: To precisely visualize cardiac anatomic structures and simultaneously depict electro-mechanical events for the purpose of precise underblood intervention. METHODS: Intracardiac high-resolution tissue Doppler imaging was used to map real time myocardial contractions in response to electrical activation within the anatomic structure of the cardiac conductive system using a canine open-chest model. RESULTS: The detailed inner anatomic structure of the cardiac conductive system at different sites (i.e., sino-atrial, atrial wall, atrial-ventricular node and ventricular wall) with the inside onset and propagation of myocardial velocity and acceleration induced by electrical activation was clearly visualized and quantitatively evaluated. CONCLUSION: The simultaneous single modality visualization of the anatomy, function and electrical events of the cardiac conductive system will foster target pacing and precision ablation.
文摘目的通过对心肌肥厚兔模型进行电生理研究,探讨心肌肥厚对心传导系统的影响。方法雄性新西兰大耳兔24只,随机分为心肌肥厚组和对照组,每组各12只。经耳缘静脉注射异丙肾上腺素制备心肌肥厚模型。造模2周后行超声检查评价造模结果。对所有动物行在体电生理检查,测量两组动物心房有效不应期(AERP)、房室结有效不应期(AVERP)、房室结反向传导有效不应期(VAERP)、窦房传导时间(SACT)、最大窦房恢复时间(SNRTMAX)、文氏周期长度(WCL),反文氏周期长度(RWCL)、房室2∶1传导频率等指标。结果心肌肥厚组AERP较对照组缩短(68.60±6.20 ms vs 77.30±12.30 ms,P<0.05),SACT、SNRTMAX、AVERP、WCL及房室2:1传导频率较对照组延长(分别为101.57±25.11 ms vs 78.33±25.17 ms,616.91±59.89 ms vs 540.64±83.18 ms,160.30±9.73 ms vs 133.80±3.89 ms,191.40±32.90 ms vs 151.10±24.30 ms,148.8±35.00 ms vs 137.30±23.40 ms,P均<0.05),而VAERP与RWCL较对照组则无明显变化(P>0.05)。结论心肌肥厚可导致心传导系统功能受损,为心肌肥厚时心律失常的发生提供条件。
