[LiAl_2(OH)_6]Cl·yH_2O was prepared by co-precipitation. The competitive intercalation of geometric isomers of hydroxybenzoic acid into the interlayer of layered double hydroxides (LDHs) was studied by the reacti...[LiAl_2(OH)_6]Cl·yH_2O was prepared by co-precipitation. The competitive intercalation of geometric isomers of hydroxybenzoic acid into the interlayer of layered double hydroxides (LDHs) was studied by the reaction of [LiAl_2(OH)_6]Cl·yH_2O with various mixtures of o-hydroxybenzoic acid, m-hydroxybenzoic acid and p-hydroxybenzoic acid. Powder X-ray diffraction (XRD) results confirmed the intercalation of the isomers, and high performance liquid chromatography (HPLC) was used for the quantitative study. The order of the preferential intercalation of the three isomers was found to be: o-hydroxybenzoic acid (1,2-C_7H_6O_3)》 p-hydroxybenzoic acid (1,4-C_7H_6O_3) > m-hydroxybenzoic acid (1,3-C_7H_6O_3).展开更多
A convenient synthesis of cis-（±） isomer 1 and trans-（±） isomer 2 of lamivudine starting from benzoyloxyacetaldehyde and 1,4-dithiane-2,5-diol is described. The key steps include chlorination of oxathiol...A convenient synthesis of cis-（±） isomer 1 and trans-（±） isomer 2 of lamivudine starting from benzoyloxyacetaldehyde and 1,4-dithiane-2,5-diol is described. The key steps include chlorination of oxathiolane lactol 5 by SOCl2/DMF, followed by coupling with silylated N^4- acetylcytosine and deprotection. The overall yield was 42.6 % and 20,1%, respectively.展开更多
In recently synthesized Cr（β-dik）Cl<sub>2</sub>L<sub>2</sub> type mixed ligand coordination compounds, β-dik represents acetylacetone （acac） and dibenzoylmethane （dbm） while L represent...In recently synthesized Cr（β-dik）Cl<sub>2</sub>L<sub>2</sub> type mixed ligand coordination compounds, β-dik represents acetylacetone （acac） and dibenzoylmethane （dbm） while L represents pyridine （Py）, γ-picoline （γ-pic） and β-picoline （β-pic）. As mentioned in [1], the stability of Cr（β-dik）Cl<sub>2</sub>（thf）<sub>2</sub> is higher than that of CrCl<sub>3</sub> （thf）<sub>3</sub>,展开更多
文摘[LiAl_2(OH)_6]Cl·yH_2O was prepared by co-precipitation. The competitive intercalation of geometric isomers of hydroxybenzoic acid into the interlayer of layered double hydroxides (LDHs) was studied by the reaction of [LiAl_2(OH)_6]Cl·yH_2O with various mixtures of o-hydroxybenzoic acid, m-hydroxybenzoic acid and p-hydroxybenzoic acid. Powder X-ray diffraction (XRD) results confirmed the intercalation of the isomers, and high performance liquid chromatography (HPLC) was used for the quantitative study. The order of the preferential intercalation of the three isomers was found to be: o-hydroxybenzoic acid (1,2-C_7H_6O_3)》 p-hydroxybenzoic acid (1,4-C_7H_6O_3) > m-hydroxybenzoic acid (1,3-C_7H_6O_3).
文摘A convenient synthesis of cis-（±） isomer 1 and trans-（±） isomer 2 of lamivudine starting from benzoyloxyacetaldehyde and 1,4-dithiane-2,5-diol is described. The key steps include chlorination of oxathiolane lactol 5 by SOCl2/DMF, followed by coupling with silylated N^4- acetylcytosine and deprotection. The overall yield was 42.6 % and 20,1%, respectively.
文摘In recently synthesized Cr（β-dik）Cl<sub>2</sub>L<sub>2</sub> type mixed ligand coordination compounds, β-dik represents acetylacetone （acac） and dibenzoylmethane （dbm） while L represents pyridine （Py）, γ-picoline （γ-pic） and β-picoline （β-pic）. As mentioned in [1], the stability of Cr（β-dik）Cl<sub>2</sub>（thf）<sub>2</sub> is higher than that of CrCl<sub>3</sub> （thf）<sub>3</sub>,
