In order to find new urea cytokinins, a series of novel fluorinated heteroaromatic ureas have been designed and synthesized, The crystal structure of 3g was further determined by single crystal X-ray diffraction to ob...In order to find new urea cytokinins, a series of novel fluorinated heteroaromatic ureas have been designed and synthesized, The crystal structure of 3g was further determined by single crystal X-ray diffraction to obtain the structural feature of this class of urea compounds. The preliminary bioassay showed that some title compounds have good cytokinin activity.展开更多
The title compound 4-(5-(2,6-difluorophenyl)-1,3,4-oxadiazol-2-ylthio)-2-(trifluoromethyl)thieno[2,3-d]pyrimidine(C15H5F5N4OS2, Mr = 416.35) was designed and synthesized as antitumor agent, and its structure was deter...The title compound 4-(5-(2,6-difluorophenyl)-1,3,4-oxadiazol-2-ylthio)-2-(trifluoromethyl)thieno[2,3-d]pyrimidine(C15H5F5N4OS2, Mr = 416.35) was designed and synthesized as antitumor agent, and its structure was determined by 1H NMR, 13C NMR, MS, elemental analysis and single-crystal X-ray diffraction. The crystal belongs to monoclinic system, space group P21/c with a = 9.904(2), b = 10.057(2), c = 16.595(3) ?, β = 100.000(3)°, V = 1627.9(6) ?3, Z = 4, F(000) = 832, Dc = 1.699 g/cm3, μ = 0.395 mm-1, R = 0.0468 and wR = 0.1255 for 4726 independent reflections(Rint = 0.0336) and 2847 observed ones(I > 2σ(I)). The in vitro antitumor activity of the title compound was preliminarily evaluated by the standard MTT assay.展开更多
对化学镀Ni—P— (CF) n 复合镀层工艺进行了较全面的研究 ,详细测定和评述了氟化石墨浓度与镀层中(CF) n 粒子含量及镀速的关系 ,以及基础镀液性质和操作条件 (如温度、pH值、搅拌方式等 )对复合镀的影响。提出了一种具有实用价值的化...对化学镀Ni—P— (CF) n 复合镀层工艺进行了较全面的研究 ,详细测定和评述了氟化石墨浓度与镀层中(CF) n 粒子含量及镀速的关系 ,以及基础镀液性质和操作条件 (如温度、pH值、搅拌方式等 )对复合镀的影响。提出了一种具有实用价值的化学镀Ni—P— (CF) n 复合镀层工艺技术。与电镀相比 ,该复合镀层无应力、难以从机体上剥离、硬度高、无磁性、耐热性好。展开更多
基金This work was funded by the National Natural Science Foundation of China(No.20072009)the Research Project from Hubei Provincial Department of Education(No.Q200529003).
文摘In order to find new urea cytokinins, a series of novel fluorinated heteroaromatic ureas have been designed and synthesized, The crystal structure of 3g was further determined by single crystal X-ray diffraction to obtain the structural feature of this class of urea compounds. The preliminary bioassay showed that some title compounds have good cytokinin activity.
基金supported by the National Natural Science Foundation of China(No.21262012)
文摘The title compound 4-(5-(2,6-difluorophenyl)-1,3,4-oxadiazol-2-ylthio)-2-(trifluoromethyl)thieno[2,3-d]pyrimidine(C15H5F5N4OS2, Mr = 416.35) was designed and synthesized as antitumor agent, and its structure was determined by 1H NMR, 13C NMR, MS, elemental analysis and single-crystal X-ray diffraction. The crystal belongs to monoclinic system, space group P21/c with a = 9.904(2), b = 10.057(2), c = 16.595(3) ?, β = 100.000(3)°, V = 1627.9(6) ?3, Z = 4, F(000) = 832, Dc = 1.699 g/cm3, μ = 0.395 mm-1, R = 0.0468 and wR = 0.1255 for 4726 independent reflections(Rint = 0.0336) and 2847 observed ones(I > 2σ(I)). The in vitro antitumor activity of the title compound was preliminarily evaluated by the standard MTT assay.
文摘对化学镀Ni—P— (CF) n 复合镀层工艺进行了较全面的研究 ,详细测定和评述了氟化石墨浓度与镀层中(CF) n 粒子含量及镀速的关系 ,以及基础镀液性质和操作条件 (如温度、pH值、搅拌方式等 )对复合镀的影响。提出了一种具有实用价值的化学镀Ni—P— (CF) n 复合镀层工艺技术。与电镀相比 ,该复合镀层无应力、难以从机体上剥离、硬度高、无磁性、耐热性好。
