Objective:Since December 2019,an outbreak of corona virus disease 2019(COVID-19)occurred in Wuhan,and rapidly spread to almost all parts of China.This was followed by prevention programs recommending Chinese medicine(...Objective:Since December 2019,an outbreak of corona virus disease 2019(COVID-19)occurred in Wuhan,and rapidly spread to almost all parts of China.This was followed by prevention programs recommending Chinese medicine(CM)for the prevention.In order to provide evidenee for CM recommendations,we reviewed ancient classics and human studies.Methods:Historical records on prevention and treatment of infections in CM classics,clinical evidence of CM on the prevention of severe acute respiratory syndrome(SARS)and H1N1 in flue nza,and CM preve ntion programs issued by health authorities in China since the COVID-19 outbreak were retrieved from differe nt databases and websites till 12 February,2020.Research evide nee in eluded data from clinical trials,cohort or other population studies using CM for preventing contagious respiratory virus diseases.Results:The use of CM to prevent epidemics of infectious diseases was traced back to ancient Chinese practice cited in Huangdi's Internal Classic(Huang Di Nei Jing)where preventive effects were recorded.There were 3 studies using CM for prevention of SARS and 4 studies for H1N1 influenza.None of the participants who took CM contracted SARS in the 3 studies.The infection rate of H1N1 in flue nza in the CM group was significantly lower than the non-CM group(relative risk 0.36,95%confidence interval 0.24-0.52;n=4).For prevention of COVID-19,23 provinces in China issued CM programs.The main principles of CM use were to tonify qi to protect from external pathoge ns,disperse wind and discharge heat,and resolve damp ness.The most frequently used herbs in eluded Radix astragali(Huangqi),Radix glycyrrhizae(Gancao),Radix saposhnikoviae(Fangfeng),Rhizoma Atractylodis Macrocephalae(Baizhu),Lonicerae Japonicae Flos(Jinyinhua),and Fructus forsythia(Lianqiao).Conclusions:Based on historical records and human evidenee of SARS and H1N1 influenza prevention,Chinese herbal formula could be an alternative approach for prevention of COVID-19 in high-risk population.Prospective,rigorous population stud展开更多
Background Clinical practice guidelines （CPGs） play an important role in healthcare in China as well as in the world. However, the current status and trends of Chinese CPGs are unknown. The aim of this study was to ...Background Clinical practice guidelines （CPGs） play an important role in healthcare in China as well as in the world. However, the current status and trends of Chinese CPGs are unknown. The aim of this study was to systematically review the present situation and the quality of Chinese CPGs published in the peer-reviewed medical literature. Methods To identify Chinese CPGs, a systematic search of relevant literature databases （CBM, WANFANG, VIP, and CNKI） was performed for the period January 1978 to December 2010. We used the AGREE II instrument to assess the quality of the included guidelines. Results We evaluated 269 guidelines published in 115 medical journals from 1993 to 2010 and produced by 256 different developers. Only four guidelines （1%） described the systematic methods for searching and selecting the evidence, 14 （5%） guidelines indicated an explicit link between the supporting evidence and the recommendations, only one guideline used the Grading of Recommendations Assessment, Development and Evaluation （GRADE） system. Thirty-one guidelines （12%） mentioned updates and the average frequency of update was 5.5 years; none described a procedure for updating the guideline. From the assessment with the Appraisal of Guidelines for Research and Ecaluation II （AGREE II）, the mean scores were low for the domains ＂scope and purpose＂ （19%） and ＂clarity of presentation＂ （26%） and very low for the other domains （＂rigour of development＂ 7%, ＂stakeholder involvement＂ 8%, ＂applicability＂ 6% and ＂editorial independence＂ 2%）. Conclusions Compared with other studies on the quality of guidelines assessed with the AGREE instrument in other countries, Chinese CPGs received lower scores, which indicates a relatively poor quality of the guidelines. However, there was some increase over time.展开更多
Tens of thousands of landslides were triggered by May 12, 2008 earthquake over a broad area. The main purpose of this article is to apply and verify earthquake-triggered landslide hazard analysis techniques by using w...Tens of thousands of landslides were triggered by May 12, 2008 earthquake over a broad area. The main purpose of this article is to apply and verify earthquake-triggered landslide hazard analysis techniques by using weight of evidence modeling in Qingshui （清水） River watershed, Deyang （德阳） City, Sichuan （四川） Province, China. Two thousand three hundred and twenty-one landslides were interpreted in the study area from aerial photographs and multi-source remote sensing imageries post-earthquake, verified by field surveys. The landslide inventory in the study area was established. A spatial database, including landslides and associated controlling parameters that may have influence on the occurrence of landslides, was constructed from topographic maps, geological maps, and enhanced thematic mapper （ETM＋） remote sensing imageries. The factors that influence landslide occurrence,such as slope angle, aspect, curvature, elevation, flow accumulation, distance from drainages, and distance from roads were calculated from the topographic maps. Lithology, distance from seismogenic fault, distance from all faults, and distance from stratigraphic boundaries were derived from the geological maps. Normalized difference vegetation index （NDV1） was extracted from ETM＋ images. Seismic intensity zoning was collected from Wenchuan （汶川） Ms8.0 Earthquake Intensity Distribution Map published by the China Earthquake Administration.Landslide hazard indices were calculated using the weight of evidence model, and landslide hazard maps were calculated from using different controlling parameters cases. The hazard map was compared with known landslide locations and verified. The success accuracy percentage of using all 13 controlling parameters was 71.82%. The resulting landslide hazard map showed five classes of landslide hazard, i.e., very high, high, moderate, low, and very low. The validation results showed satisfactory agreement between the hazard map and the existing landslides distribution data.展开更多
基金Supported by the National Natural Science Foundation of China(No.81830115),ChinaProf.Nicola Robinson(visiting professor of Beijing University of Chinese Medicine)is supported by the Overseas Expertise Project,Ministry of Education of China(No.MS20080009)。
文摘Objective:Since December 2019,an outbreak of corona virus disease 2019(COVID-19)occurred in Wuhan,and rapidly spread to almost all parts of China.This was followed by prevention programs recommending Chinese medicine(CM)for the prevention.In order to provide evidenee for CM recommendations,we reviewed ancient classics and human studies.Methods:Historical records on prevention and treatment of infections in CM classics,clinical evidence of CM on the prevention of severe acute respiratory syndrome(SARS)and H1N1 in flue nza,and CM preve ntion programs issued by health authorities in China since the COVID-19 outbreak were retrieved from differe nt databases and websites till 12 February,2020.Research evide nee in eluded data from clinical trials,cohort or other population studies using CM for preventing contagious respiratory virus diseases.Results:The use of CM to prevent epidemics of infectious diseases was traced back to ancient Chinese practice cited in Huangdi's Internal Classic(Huang Di Nei Jing)where preventive effects were recorded.There were 3 studies using CM for prevention of SARS and 4 studies for H1N1 influenza.None of the participants who took CM contracted SARS in the 3 studies.The infection rate of H1N1 in flue nza in the CM group was significantly lower than the non-CM group(relative risk 0.36,95%confidence interval 0.24-0.52;n=4).For prevention of COVID-19,23 provinces in China issued CM programs.The main principles of CM use were to tonify qi to protect from external pathoge ns,disperse wind and discharge heat,and resolve damp ness.The most frequently used herbs in eluded Radix astragali(Huangqi),Radix glycyrrhizae(Gancao),Radix saposhnikoviae(Fangfeng),Rhizoma Atractylodis Macrocephalae(Baizhu),Lonicerae Japonicae Flos(Jinyinhua),and Fructus forsythia(Lianqiao).Conclusions:Based on historical records and human evidenee of SARS and H1N1 influenza prevention,Chinese herbal formula could be an alternative approach for prevention of COVID-19 in high-risk population.Prospective,rigorous population stud
文摘Background Clinical practice guidelines （CPGs） play an important role in healthcare in China as well as in the world. However, the current status and trends of Chinese CPGs are unknown. The aim of this study was to systematically review the present situation and the quality of Chinese CPGs published in the peer-reviewed medical literature. Methods To identify Chinese CPGs, a systematic search of relevant literature databases （CBM, WANFANG, VIP, and CNKI） was performed for the period January 1978 to December 2010. We used the AGREE II instrument to assess the quality of the included guidelines. Results We evaluated 269 guidelines published in 115 medical journals from 1993 to 2010 and produced by 256 different developers. Only four guidelines （1%） described the systematic methods for searching and selecting the evidence, 14 （5%） guidelines indicated an explicit link between the supporting evidence and the recommendations, only one guideline used the Grading of Recommendations Assessment, Development and Evaluation （GRADE） system. Thirty-one guidelines （12%） mentioned updates and the average frequency of update was 5.5 years; none described a procedure for updating the guideline. From the assessment with the Appraisal of Guidelines for Research and Ecaluation II （AGREE II）, the mean scores were low for the domains ＂scope and purpose＂ （19%） and ＂clarity of presentation＂ （26%） and very low for the other domains （＂rigour of development＂ 7%, ＂stakeholder involvement＂ 8%, ＂applicability＂ 6% and ＂editorial independence＂ 2%）. Conclusions Compared with other studies on the quality of guidelines assessed with the AGREE instrument in other countries, Chinese CPGs received lower scores, which indicates a relatively poor quality of the guidelines. However, there was some increase over time.
基金supported by the International Scientific Joint Project of China (No. 2009DFA21280)the National Natural Science Foundation of China (No. 40821160550)the Doctoral Candidate Innovation Research Support Program by Science & Technology Review (No. kjdb200902-5)
文摘Tens of thousands of landslides were triggered by May 12, 2008 earthquake over a broad area. The main purpose of this article is to apply and verify earthquake-triggered landslide hazard analysis techniques by using weight of evidence modeling in Qingshui （清水） River watershed, Deyang （德阳） City, Sichuan （四川） Province, China. Two thousand three hundred and twenty-one landslides were interpreted in the study area from aerial photographs and multi-source remote sensing imageries post-earthquake, verified by field surveys. The landslide inventory in the study area was established. A spatial database, including landslides and associated controlling parameters that may have influence on the occurrence of landslides, was constructed from topographic maps, geological maps, and enhanced thematic mapper （ETM＋） remote sensing imageries. The factors that influence landslide occurrence,such as slope angle, aspect, curvature, elevation, flow accumulation, distance from drainages, and distance from roads were calculated from the topographic maps. Lithology, distance from seismogenic fault, distance from all faults, and distance from stratigraphic boundaries were derived from the geological maps. Normalized difference vegetation index （NDV1） was extracted from ETM＋ images. Seismic intensity zoning was collected from Wenchuan （汶川） Ms8.0 Earthquake Intensity Distribution Map published by the China Earthquake Administration.Landslide hazard indices were calculated using the weight of evidence model, and landslide hazard maps were calculated from using different controlling parameters cases. The hazard map was compared with known landslide locations and verified. The success accuracy percentage of using all 13 controlling parameters was 71.82%. The resulting landslide hazard map showed five classes of landslide hazard, i.e., very high, high, moderate, low, and very low. The validation results showed satisfactory agreement between the hazard map and the existing landslides distribution data.
