Remote monitoring of transmission lines of a power system is significant for improved reliability and stability during fault conditions and protection system breakdowns.This paper proposes a smart backup monitoring sy...Remote monitoring of transmission lines of a power system is significant for improved reliability and stability during fault conditions and protection system breakdowns.This paper proposes a smart backup monitoring system for detecting and classifying the type of transmission line fault occurred in a power grid.In contradiction to conventional methods,transmission line fault occurred at any locality within power grid can be identified and classified using measurements from phasor measurement unit(PMU)at one of the generator buses.This minimal requirement makes the proposed methodology ideal for providing backup protection.Spectral analysis of equivalent power factor angle(EPFA)variation has been adopted for detecting the occurrence of fault that occurred anywhere in the grid.Classification of the type of fault occurred is achieved from the spectral coefficients with the aid of artificial intelligence.The proposed system can considerably assist system protection center(SPC)in fault localization and to restore the line at the earliest.Effectiveness of proposed system has been validated using case studies conducted on standard power system networks.展开更多
Diabetic chronic wound,characterized by prolonged inflammation and impaired angiogenesis,has become one of the most serious challenges in clinic and pose a significant healthcare burden worldwide.Although a great vari...Diabetic chronic wound,characterized by prolonged inflammation and impaired angiogenesis,has become one of the most serious challenges in clinic and pose a significant healthcare burden worldwide.Although a great variety of wound dressings have been developed,few of encouraged achievements were obtained so far.In this study,the gene-activated strategy was applied to enhance sustained expression of vascular endothelial growth factor(VEGF)and achieve better healing outcomes by regulating inflammation and promoting angiogenesis.The gene-activated bilayer dermal equivalents(Ga-BDEs),which has good biocompatibility,were fabricated by loading the nano-sized complexes of Lipofectamine 2000/plasmid DNA-encoding VEGF into a collagen-chitosan scaffold/silicone membrane bilayer dermal equivalent.The DNA complexes were released in a sustained manner and showed the effective transfection capacities to up-regulate the expression of VEGF in vitro.To overcome cutaneous contraction of rodents and mimic the wound healing mechanisms of the human,a reformative rat model of full-thickness diabetic chronic wound was adopted.Under the treatment of Ga-BDEs,speeding wound healing was observed,which is accompanied by the accelerated infiltration and phenotype shift of macrophages and enhanced angiogenesis in early and late healing phases,respectively.These proved that Ga-BDEs possess the functions of immunomodulation and pro-angiogenesis simultaneously.Subsequently,the better regeneration outcomes,including deposition of oriented collagen and fast reepithelialization,were achieved.All these results indicated that,being different from traditional pro-angiogenic concept,the up-regulated expression of VEGF by Ga-BDEs in a sustained manner shows versatile potentials for promoting the healing of diabetic chronic wounds.展开更多
文摘Remote monitoring of transmission lines of a power system is significant for improved reliability and stability during fault conditions and protection system breakdowns.This paper proposes a smart backup monitoring system for detecting and classifying the type of transmission line fault occurred in a power grid.In contradiction to conventional methods,transmission line fault occurred at any locality within power grid can be identified and classified using measurements from phasor measurement unit(PMU)at one of the generator buses.This minimal requirement makes the proposed methodology ideal for providing backup protection.Spectral analysis of equivalent power factor angle(EPFA)variation has been adopted for detecting the occurrence of fault that occurred anywhere in the grid.Classification of the type of fault occurred is achieved from the spectral coefficients with the aid of artificial intelligence.The proposed system can considerably assist system protection center(SPC)in fault localization and to restore the line at the earliest.Effectiveness of proposed system has been validated using case studies conducted on standard power system networks.
基金financially supported by the National Natural Science Foundation of China(51873184,81671918)National Key R&D Program of China(2016YFC1101000).
文摘Diabetic chronic wound,characterized by prolonged inflammation and impaired angiogenesis,has become one of the most serious challenges in clinic and pose a significant healthcare burden worldwide.Although a great variety of wound dressings have been developed,few of encouraged achievements were obtained so far.In this study,the gene-activated strategy was applied to enhance sustained expression of vascular endothelial growth factor(VEGF)and achieve better healing outcomes by regulating inflammation and promoting angiogenesis.The gene-activated bilayer dermal equivalents(Ga-BDEs),which has good biocompatibility,were fabricated by loading the nano-sized complexes of Lipofectamine 2000/plasmid DNA-encoding VEGF into a collagen-chitosan scaffold/silicone membrane bilayer dermal equivalent.The DNA complexes were released in a sustained manner and showed the effective transfection capacities to up-regulate the expression of VEGF in vitro.To overcome cutaneous contraction of rodents and mimic the wound healing mechanisms of the human,a reformative rat model of full-thickness diabetic chronic wound was adopted.Under the treatment of Ga-BDEs,speeding wound healing was observed,which is accompanied by the accelerated infiltration and phenotype shift of macrophages and enhanced angiogenesis in early and late healing phases,respectively.These proved that Ga-BDEs possess the functions of immunomodulation and pro-angiogenesis simultaneously.Subsequently,the better regeneration outcomes,including deposition of oriented collagen and fast reepithelialization,were achieved.All these results indicated that,being different from traditional pro-angiogenic concept,the up-regulated expression of VEGF by Ga-BDEs in a sustained manner shows versatile potentials for promoting the healing of diabetic chronic wounds.
