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三七总皂苷对线粒体调控作用的研究进展 被引量:28
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作者 杨子平 包怡敏 《中国中药杂志》 CAS CSCD 北大核心 2017年第5期870-874,共5页
线粒体是细胞关键的能量来源,在能量合成与释放、细胞功能维持方面具有重要作用。三七总皂苷作为中药三七中最重要的活性成分,具有抗血栓形成、扩血管、降血压、抗炎、抗氧化等作用。国内外研究表明,三七总皂苷参与调节线粒体能量代谢... 线粒体是细胞关键的能量来源,在能量合成与释放、细胞功能维持方面具有重要作用。三七总皂苷作为中药三七中最重要的活性成分,具有抗血栓形成、扩血管、降血压、抗炎、抗氧化等作用。国内外研究表明,三七总皂苷参与调节线粒体能量代谢、氧化应激、生物合成、凋亡与自噬及膜通道状态等,故线粒体是三七总皂苷生物活性的重要靶点。该文就三七总皂苷对线粒体的调控作用做一综述。 展开更多
关键词 三七总皂苷 线粒体 能量代谢 氧化应激 线粒体ATP敏感性钾通道 线粒体自噬 线粒体膜通透性转换孔
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Oil and gas cooperation between China and Central Asia in an environment of political and resource competition 被引量:10
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作者 Hu Bin 《Petroleum Science》 SCIE CAS CSCD 2014年第4期596-605,共10页
This paper investigates Central Asia's oil and gas resources, special geopolitics and energy competition, and approaches, challenges and prospects in cooperation between China and Central Asia. The objective is to pr... This paper investigates Central Asia's oil and gas resources, special geopolitics and energy competition, and approaches, challenges and prospects in cooperation between China and Central Asia. The objective is to propose measures for oil and gas cooperation between China and Central Asia. Central Asia is rich in oil and gas resources. Its remaining recoverable reserves of crude oil and natural gas account for 1.9% and 10.6 %, respectively, of the world's total reserves. Moreover, there is great exploration and development potential. As a strategic channel connecting Eurasia, Central Asia has a prominent geopolitical status. Many powerful countries such as the United States, Russia and China, as well as Europe, have an intense energy competition in Central Asia. In the oil and gas cooperation with Central Asia, the China National Petroleum Corporation (CNPC) focuses on establishing a coordination group, promoting overall oil and gas business opportunities and sustainable development, innovating and applying specialty engineering technology and improving project economic benefits. Through its efforts over the last nearly two decades, the China National Petroleum Corporation has completed a 50-million-tonne a year oil and gas production centre in Central Asia and oil and gas pipelines passing through multiple countries, becoming an important channel for securing China's energy imports. If appropriate measures are taken in the 'Thirteenth Five-Year Plan' period or later, the China National Petroleum Corporation will develop a 100-million-tonne p.a. oil and gas production centre in Central Asia and a strategic oil and gas import channel exceeding this amount of production. This cooperation between China and Central Asia is however faced with the following challenges: increasing multinational competition uncertainty, potential risks in the political systems of Central Asian countries, frequently occurring violence and also resource policy tightening in Central Asia. To further oil and gas cooperation w 展开更多
关键词 Central Asia oil and gas COOPERATION COMPETITION energy channels oil and gas productioncentre mode innovation PROPOSAL
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海上能源通道安全与中国海权发展 被引量:10
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作者 周云亨 余家豪 《太平洋学报》 CSSCI 2014年第3期66-76,共11页
凭借全球军事投射能力,美国能在中国难以掌控的国际能源咽喉要道影响中国海外能源供应。限于自身实力,中国在近期内奉行搭便车战略是潜在的政策选择,但难免会受制于人。中美两国的竞争关系,以及两国在海洋领域矛盾的凸显,决定了中国在... 凭借全球军事投射能力,美国能在中国难以掌控的国际能源咽喉要道影响中国海外能源供应。限于自身实力,中国在近期内奉行搭便车战略是潜在的政策选择,但难免会受制于人。中美两国的竞争关系,以及两国在海洋领域矛盾的凸显,决定了中国在中长期时段必须采取自助战略,发展本国的海上力量。对此,中国在推进陆上油气通道建设的同时,还应做好以下几方面工作:制定相应的国家海洋发展战略;发展一支能执行多种任务的蓝水海军;提高海上公共产品的供应能力;加强对国际海洋法体系的研究与建设;发展本国的海运能力和造船工业。 展开更多
关键词 海上能源 安全 美国因素 中国海权
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《丹溪心法》对经络证治的学术贡献 被引量:9
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作者 马啸 吕福全 《天津中医药大学学报》 CAS 2017年第3期178-179,共2页
《丹溪心法》是由其弟子戴元礼、赵以德、刘淑渊等整理朱丹溪之心得,是一部比较全面反映朱丹溪临床治疗经验的医学著作,该书对经络的认识有独到的见解。朱丹溪提出的十二经见证、手足阴阳经合生见证,是对经络病候、诊断归经的充实和完善... 《丹溪心法》是由其弟子戴元礼、赵以德、刘淑渊等整理朱丹溪之心得,是一部比较全面反映朱丹溪临床治疗经验的医学著作,该书对经络的认识有独到的见解。朱丹溪提出的十二经见证、手足阴阳经合生见证,是对经络病候、诊断归经的充实和完善,进一步发展了《内经》的经络学说,丰富了中医学基础理论的内容;灸法有补火泻火的功效,对灸法临床应用有一定的指导作用。 展开更多
关键词 《丹溪心法》 经络 学术贡献
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The molecular dynamics of neural metabolism during the action potential 被引量:6
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作者 ZHENG HongWen WANG RuBin +1 位作者 QIAO LinKun DU Ying 《Science China(Technological Sciences)》 SCIE EI CAS 2014年第5期857-863,共7页
Neural information processing is tightly coupled to both energy consumption and derivation from substrates.In this study,the energy function of the neuron during the action potential(AP)is described and analyzed.It ha... Neural information processing is tightly coupled to both energy consumption and derivation from substrates.In this study,the energy function of the neuron during the action potential(AP)is described and analyzed.It has been observed that energy consumption during the AP does not match predictions of the conventional theory of neural energy dynamics.On short time scales,neural energy expenditure shifts between positive and negative phases.During the AP,the energy source switches from neuronal stores(positive expenditure or net consumption)to exploitation of external substrates,specifically the glucose and oxygen carried in cerebral blood(the negative consumption phase).Based on the idea of reductionism,this paper demonstrates how ion channels,membrane pumps and transporters,ionotropic and metabotropic receptor signaling pathways,astrocyte glycolysis and the production lactate,and the glutamate-glutamine cycle all serve to relate cerebral blood flow and neuronal metabolism to neuronal activity and so maintain neuronal energy charge during the AP. 展开更多
关键词 neural energy action potential ion channels ASTROCYTES HYPERAEMIA
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Multi-Sinusoidal Waveform Shaping for Integrated Data and Energy Transfer in Aging Channels 被引量:1
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作者 Jie Hu Yaping Hou Kun Yang 《China Communications》 SCIE CSCD 2023年第4期243-258,共16页
Integrated data and energy transfer(IDET)is capable of simultaneously delivering on-demand data and energy to low-power Internet of Everything(Io E)devices.We propose a multi-carrier IDET transceiver relying on superp... Integrated data and energy transfer(IDET)is capable of simultaneously delivering on-demand data and energy to low-power Internet of Everything(Io E)devices.We propose a multi-carrier IDET transceiver relying on superposition waveforms consisting of multi-sinusoidal signals for wireless energy transfer(WET)and orthogonal-frequency-divisionmultiplexing(OFDM)signals for wireless data transfer(WDT).The outdated channel state information(CSI)in aging channels is employed by the transmitter to shape IDET waveforms.With the constraints of transmission power and WDT requirement,the amplitudes and phases of the IDET waveform at the transmitter and the power splitter at the receiver are jointly optimised for maximising the average directcurrent(DC)among a limited number of transmission frames with the existence of carrier-frequencyoffset(CFO).For the amplitude optimisation,the original non-convex problem can be transformed into a reversed geometric programming problem,then it can be effectively solved with existing tools.As for the phase optimisation,the artificial bee colony(ABC)algorithm is invoked in order to deal with the nonconvexity.Iteration between the amplitude optimisation and phase optimisation yields our joint design.Numerical results demonstrate the advantage of our joint design for the IDET waveform shaping with the existence of the CFO and the outdated CSI. 展开更多
关键词 integrated data and energy transfer(IDET) wireless energy transfer(WET) simultaneous wireless information and power transfer(SWIPT) carrier-frequency-offset(CFO) WAVEFORM aging channels outdated channel state information(CSI) orthogonal frequency division multiplexing(OFDM)
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金融促进“一带一路”能源合作的依据与路径选择——基于中国一次能源现状的视角 被引量:3
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作者 孙佳燕 金泽虎 《巢湖学院学报》 2015年第4期50-58,共9页
促进能源贸易合作是"一带一路"战略建设的重要组成部分。文章通过对我国一次能源严重供不应求现状的分析,利用要素禀赋理论说明能源贸易合作的重要性。金融对"一带一路"能源合作的促进要落到实处,就要依托现存的与... 促进能源贸易合作是"一带一路"战略建设的重要组成部分。文章通过对我国一次能源严重供不应求现状的分析,利用要素禀赋理论说明能源贸易合作的重要性。金融对"一带一路"能源合作的促进要落到实处,就要依托现存的与未来的金融渠道,推动"一带一路"的沿线相关国家及其能源产业合作,进而促进能源相关产业发展,实现"一带一路"沿线相关国家在中国经济新常态下的共同进步。 展开更多
关键词 一带一路 能源合作 要素禀赋 金融渠道
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基于多信道的能量高效传感器节点调度算法 被引量:2
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作者 张治学 曾波 +1 位作者 张各各 王辉 《计算机工程》 CAS CSCD 北大核心 2015年第9期135-139,共5页
在无线传感器网络中,传统时分多址(TDMA)调度算法未考虑节点在不同状态间切换时所耗费的能量,缩短了网络生存时间。为此,提出一种基于接收端的时分多址时隙分配算法。时隙分配过程始于数据汇聚节点,以节点的数据量为偏移,父节点以自身... 在无线传感器网络中,传统时分多址(TDMA)调度算法未考虑节点在不同状态间切换时所耗费的能量,缩短了网络生存时间。为此,提出一种基于接收端的时分多址时隙分配算法。时隙分配过程始于数据汇聚节点,以节点的数据量为偏移,父节点以自身的时隙为基础为其子节点分配时隙,以保证每个节点的传输活动满足连续接收-发送模式,并将节点的状态切换次数最小化为2次,降低节点能量消耗。采用优化的多信道分配机制,通过将节点时隙分派给不同信道,解决节点间时隙分配冲突问题,并实现时隙重用与信道数优化。仿真结果表明,在数据汇聚传感器网络中,与多跳TDMA和集中式TDMA调度算法相比,该算法节省了约10%的传感器网络能量,降低了数据汇聚时间。 展开更多
关键词 无线传感器网络 能量消耗 多信道 调度算法 时隙
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双流道太阳能空气集热器关键参数影响特性分析 被引量:2
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作者 张建军 王林军 +1 位作者 张东 景金龙 《机械设计与制造工程》 2020年第7期92-96,共5页
针对改型设计的平板型双流道太阳能空气集热器,搭建了实验平台,利用Fluent软件开展了关键参数对集热器集热性能的试验及模拟研究。结果表明:模拟所得太阳能空气集热器集热效率和出口空气温度与实验值具有良好的一致性;出口空气温度受太... 针对改型设计的平板型双流道太阳能空气集热器,搭建了实验平台,利用Fluent软件开展了关键参数对集热器集热性能的试验及模拟研究。结果表明:模拟所得太阳能空气集热器集热效率和出口空气温度与实验值具有良好的一致性;出口空气温度受太阳辐射强度的影响较大,而集热效率受太阳辐射强度影响较小;最优空气质量流量为0.06 kg/s;随着进口空气温度的增加,出口空气温度也增加,但进出口空气的温差在缩小,集热效率在下降;适当增加吸热板厚度可以有效提高出口空气温度和集热效率,但过量增加吸热板厚度不能持续提升集热系统的性能,推荐的吸热板厚度为0.35 mm。 展开更多
关键词 太阳能 空气集热器 双流道 实验验证 关键参数 热力性能
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Cement-and-pebble nanofluidic membranes with stable acid resistance as osmotic energy generators 被引量:1
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作者 Yifei Zhao Weiwen Xin +6 位作者 Yongchao Qian Zhehua Zhang Yadong Wu Xiangbin Lin Xiang-Yu Kong Lei Jiang Liping Wen 《Science China Materials》 SCIE EI CAS CSCD 2022年第10期2729-2736,共8页
Osmotic energy between river water and seawater has attracted interest as a new source of sustainable energy.Nanofluidic membranes in a reverse electrodialysis configuration can capture energy from salinity gradients.... Osmotic energy between river water and seawater has attracted interest as a new source of sustainable energy.Nanofluidic membranes in a reverse electrodialysis configuration can capture energy from salinity gradients.However,current membrane materials suffer from high resistances,low stabilities,and low charge densities,which limit their further application.Here,we designed a high-performance nanofluidic membrane using carboxylic cellulose nanofibers functionalized with graphene oxide nanolamellas with cement-and-pebble microstructures and stable skeletons for enhanced ion transmembrane transport.By mixing artificial river water and seawater,the composite membrane achieved a high output power density up to 5.26 W m^(−2).Additionally,the membrane had an excellent acid resistance,which enabled long-term use with over 67 W m^(−2) of power density.The performance of this composite membrane benefited from the mechanically strong cellulose fibers and the bonding between nanofibers and nanolamellas.In this work,we highlight promising directions in industrial waste treatment using energy extracted from chemical potential gradients. 展开更多
关键词 cement-and-pebble membrane ion transport osmotic energy conversion nanoconfined fluidic channels chargedriven ion diffusion
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能源价格与粮食价格关系的研究综述 被引量:2
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作者 尹靖华 《浙江外国语学院学报》 2017年第1期95-101,共7页
能源价格是影响粮食价格的重要因素之一,因此学界围绕能源价格和粮食价格的关联性以及能源价格对粮食价格的影响机制开展了大量研究。研究结果表明:粮食期货价格和能源期货价格之间不存在长期均衡关系,仅存在短期动态关系;而粮食现货价... 能源价格是影响粮食价格的重要因素之一,因此学界围绕能源价格和粮食价格的关联性以及能源价格对粮食价格的影响机制开展了大量研究。研究结果表明:粮食期货价格和能源期货价格之间不存在长期均衡关系,仅存在短期动态关系;而粮食现货价格和能源现货价格之间存在长期均衡关系和短期动态关系。能源价格对粮食价格传导的渠道有生产成本渠道、生物能源需求渠道和运输成本渠道。 展开更多
关键词 能源价格 粮食价格 关联性 传导渠道
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“一带一路”战略下提升国家能源安全的措施探讨
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作者 杨小朋 郭佳 彭莉莉 《煤炭经济研究》 2016年第11期35-38,共4页
从常规能源储量、能源进口区域和能源进口通道等方面分析了中国能源安全面临的形势和压力,认为应该在"一带一路"战略的实施下,与周边国家广泛开展能源合作,丰富中国能源进口渠道,建设新疆综合能源基地,优化能源供给结构,调整... 从常规能源储量、能源进口区域和能源进口通道等方面分析了中国能源安全面临的形势和压力,认为应该在"一带一路"战略的实施下,与周边国家广泛开展能源合作,丰富中国能源进口渠道,建设新疆综合能源基地,优化能源供给结构,调整能源消费结构,推广新能源汽车5个方面,拉动电力能源需求,推动能源生产革命和消费革命,提高国家能源安全保障能力,提升国家总体安全水平。 展开更多
关键词 能源安全 能源通道 综合能源基地 电化中国 新能源汽车
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论中国古代文人画审美特质的多种因素
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作者 王勇 《芜湖职业技术学院学报》 2002年第3期33-36,共4页
对于中国古代文人画形成的审美特质研究,仅仅只局限于儒、道、禅三方面未免有些单一,从神权、经脉和丹田之气这几个方面阐述古代绘画的审美思想出发,我们可以求得对于中国绘画更为深入的理解和感受。
关键词 中国 古代 文人画 审美特质 神权 丹田 经脉 玄学 审美思想 绘画
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The Belt and Road Initiatives and China's International Energy Cooperation: Progress, Mechanisms, and Recommendations
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作者 Qian Xu-ming 《Cultural and Religious Studies》 2017年第2期85-94,共10页
China's international energy cooperation and energy security are important parts of The Belt and Road initiatives. China and the countries along the Belt and Road continue to promote cooperation, actively use the exi... China's international energy cooperation and energy security are important parts of The Belt and Road initiatives. China and the countries along the Belt and Road continue to promote cooperation, actively use the existing bilateral and multilateral cooperation mechanisms to promote the regional and inter-regional energy cooperation. Countries along the Belt and Road are rich in oil and gas resources; their demand on the diversification of export meet with the diversification demand on imports of consumption countries; and their oil refining and chemical technology as well as construction capacity is weak, which provides a lot of new opportunities in cooperation for Chinese enterprises. However, the energy cooperation of Chinese enterprises are also facing some challenges in the complex environment of energy cooperation, the interference of big powers, non-traditional security threats, and energy policy factors. Finally, the paper puts forward the strategic thinking of China's international energy cooperation under the new situation. 展开更多
关键词 The Belt and Road initiatives China's international energy cooperation energy cooperation mechanism energy strategic channels
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金融促进“一带一路”能源合作的依据与路径选择——基于中国一次能源现状的视角 被引量:1
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作者 孙佳燕 金泽虎 《安徽电气工程职业技术学院学报》 2015年第2期49-56,共8页
促进能源贸易合作是"一带一路"战略建设的重要组成部分。文章通过对我国一次能源严重供不应求现状的分析,利用要素禀赋理论说明能源贸易合作的重要性。那么金融对"一带一路"能源合作的促进如何落到实处,就要依托现... 促进能源贸易合作是"一带一路"战略建设的重要组成部分。文章通过对我国一次能源严重供不应求现状的分析,利用要素禀赋理论说明能源贸易合作的重要性。那么金融对"一带一路"能源合作的促进如何落到实处,就要依托现存的与未来的金融渠道,推动"一带一路"的沿线相关国家及其能源产业合作,进而促进能源相关产业发展,实现"一带一路"沿线相关国家在中国经济新常态下的共同进步。 展开更多
关键词 一带一路 能源合作 要素禀赋 金融渠道
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Energy pharmacological effects of chemical drugs
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作者 Rui-Ping Li Yan Liu +2 位作者 Zhu Wang Zhi-Yong Wang Wan-Sen Sun 《Medical Theory and Hypothesis》 2022年第3期1-4,共4页
Background:To study the energy pharmacological effects of chemical drugs.Methods:The energy pharmacological effects of chemical drugs were studied using a literature induction method.Results:Chemical drugs have energy... Background:To study the energy pharmacological effects of chemical drugs.Methods:The energy pharmacological effects of chemical drugs were studied using a literature induction method.Results:Chemical drugs have energy properties,which can be expressed in terms of cold,hot,warm,and cool.The energy properties of chemical drugs have energy pharmacological effects,which are related to the bond energy release and absorption of intermolecular chemical bonds,where the release of energy from chemical bonds indicates a warm-hot energy pharmacological effect and the absorption of energy indicates a cold energy pharmacological effect.The mechanisms of chemical drug energy may be related to the presence of temperature-sensitive ion channels in the body.Conclusion:Chemical drugs exhibit energy pharmacological effects. 展开更多
关键词 chemical drugs energy pharmacological effects temperature sensing ion channels
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基于能源安全的中国国际能源通道建设研究
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作者 姜巍 高卫东 《干旱区资源与环境》 CSSCI CSCD 北大核心 2011年第6期54-58,共5页
能源是国家工业化的基本保障,然而中国近年来规模日益增加的能源进口使得其能源保障成为国际社会共同关注的问题。文中从中国当前能源生产和消费特征入手,分析了中国当前的能源系统特点:从数量上看,尽管规模可观但落后的资源结构使得... 能源是国家工业化的基本保障,然而中国近年来规模日益增加的能源进口使得其能源保障成为国际社会共同关注的问题。文中从中国当前能源生产和消费特征入手,分析了中国当前的能源系统特点:从数量上看,尽管规模可观但落后的资源结构使得中国不得不大量进口现代能源矿种石油,因此目前中国石油对外依存度已达60%;从运输途径上看,海上运输仍然是我国当前主要的石油运输方式;从来源地看,中国的主要石油供应地区集中在中东和西非;从运输路线来看,中国高度依赖马六甲海峡。为保障我国能源通道安全,需要加强中国国际能源通道的建设与拓展,从地理和经济可行性的角度分析和阐述了中国未来石油进口可能的途径及存在风险,并从能源安全的角度提出了解决上述问题的建议。 展开更多
关键词 能源安全 能源通道 可持续发展
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ENHANCING OIL AND GAS CONSUMPTION THROUGH MULTI-CHANNELS──Trend Analysis of China's Energy Strategy Re-adjustment
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《China Oil & Gas》 CAS 1999年第3期154-159,共6页
关键词 GAS Trend Analysis of China’s energy Strategy Re-adjustment RE ENHANCING OIL AND GAS CONSUMPTION THROUGH MULTI-channels
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Cross-Layer Design for EH Systems with Finite Buffer Constraints
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作者 Mohammed Baljon Shailendra Mishra 《Computers, Materials & Continua》 SCIE EI 2021年第10期129-144,共16页
Energy harvesting(EH)technology in wireless communication is a promising approach to extend the lifetime of future wireless networks.A cross-layer optimal adaptation policy for a point-to-point energy harvesting(EH)wi... Energy harvesting(EH)technology in wireless communication is a promising approach to extend the lifetime of future wireless networks.A cross-layer optimal adaptation policy for a point-to-point energy harvesting(EH)wireless communication system with finite buffer constraints over a Rayleigh fading channel based on a Semi-Markov Decision Process(SMDP)is investigated.Most adaptation strategies in the literature are based on channeldependent adaptation.However,besides considering the channel,the state of the energy capacitor and the data buffer are also involved when proposing a dynamic modulation policy for EH wireless networks.Unlike the channeldependent policy,which is a physical layer-based optimization,the proposed cross-layer dynamic modulation policy is a guarantee to meet the overflow requirements of the upper layer by maximizing the throughput while optimizing the transmission power and minimizing the dropping packets.Based on the states of the channel conditions,data buffer,and energy capacitor,the scheduler selects a particular action corresponding to the selected modulation constellation.Moreover,the packets are modulated into symbols according to the selected modulation type to be ready for transmission over the Rayleigh fading channel.Simulations are used to test the performance of the proposed cross-layer policy scheme,which shows that it significantly outperforms the physical layer channel-dependent policy scheme in terms of throughput only. 展开更多
关键词 energy harvesting technology cross-layer design delay tolerant network fading channels resource allocation telecommunication power management telecommunication scheduling
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Survey of deep sub-barrier heavy-ion fusion hindrance phenomenon for positive and negative Q-value systems using the proximity-type potential
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作者 R.Gharaei A.Fuji B.Azadegan 《Chinese Physics C》 SCIE CAS CSCD 2021年第12期94-105,共12页
A systematic survey of the accurate measurements of heavy-ion fusion cross sections at extreme sub-barrier energies is performed using the coupled-channels(CC)theory that is based on the proximity formalism.This work ... A systematic survey of the accurate measurements of heavy-ion fusion cross sections at extreme sub-barrier energies is performed using the coupled-channels(CC)theory that is based on the proximity formalism.This work theoretically explores the role of the surface energy coefficient and energy-dependent nucleus-nucleus proxim-ity potential in the mechanism of the fusion hindrance of 14 typical colliding systems with negative Q-values,in-eluding ^(11a)B+^(197)AU,^(12)C+^(198)Pt,^(16)O+^(208)Pb,^(28)Si+^(94Mo),^(48)Ca+^(96)Zr,^(28Si+)^(64)Ni,^(58)Ni+^(58)Ni+,^(60)Ni+^(89)Y,^(12)C+^(204)Pb,^(36)S+^(64)Ni,^(36)S+^(90)Zr,^(40)Ca+^(90)Zr,^(40)Ca+^(40Ca)and ^(48)Ca+^(48)Ca,,as well as five typical colliding systems with positive Q-values,ineluding ^(12)C+^(30)Si,^24Mg+^(30)Si,^(36)Si+^(48)Ca, and ^(40)Ca+^(48)Ca.It is shown that the outcomes based on the proximity potential along with the above-mentioned physical effects achieve reasonable agreement with the experimentally observed data of the fusion cross sections(Tfus(£),astrophysical S(E)factors,and logarithmic derivatives L(E)in the energy region far below the Coulomb barrier.A discussion is also presented on the performance of the present theoretical approach in reproducing the experimental fusion barrier distributions for different colliding systems. 展开更多
关键词 thermal properties of hot nuclei surface energy coefficient proximity formalism fusion hindrance coupled-channels effects
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