目的:探讨盐酸沙格雷酯治疗下肢动脉硬化闭塞症(arteriosclerotic obliterans,ASO)支架置入术后患者的疗效。方法:2008年6月至2009年10月,共52例因ASO而行下肢动脉支架置入术的患者,共57条患肢,随机分成两组,治疗组(26例,29条患肢)给予...目的:探讨盐酸沙格雷酯治疗下肢动脉硬化闭塞症(arteriosclerotic obliterans,ASO)支架置入术后患者的疗效。方法:2008年6月至2009年10月,共52例因ASO而行下肢动脉支架置入术的患者,共57条患肢,随机分成两组,治疗组(26例,29条患肢)给予盐酸沙格雷酯100mg/次,3次/d,口服,对照组(26例,28条患肢)给予胰激肽原酶肠溶片120U,3次/d,口服。治疗6个月后从患者症状、跛行距离(distance of claudication,DOC)、踝肱指数(ankle/brachial index,ABI)、经皮氧分压(transcutaneousoxygen pressure,TcPO2)、支架再狭窄率、药物不良反应等方面判断治疗效果。结果:和对照组相比,治疗组术前ABI、TcPO2及DOC差异无统计学意义(P>0.05);术后2 w ABI、TcPO2差异无统计学意义(P>0.05);术后6个月ABI差异无统计学意义(P>0.05),TcPO2及DOC均改善,差异有统计学意义(P<0.05);治疗组主观感觉症状改善者25例,出现支架再狭窄1例,对照组主观感觉改善者22例,支架再狭窄3例,两者差异无统计学意义(P>0.05);治疗组支架两组术后用药未见明显不良反应。结论:盐酸沙格雷酯用于ASO支架置入术后治疗效果明确,安全、方便,值得推广。展开更多
We could observe the endoluminal stent graft (SG) following thoracic endovascular aneurysm repair (TEVAR) by a coronary artery angioscope and establish intravascular visualization of SG. The patient was a 70-year-old ...We could observe the endoluminal stent graft (SG) following thoracic endovascular aneurysm repair (TEVAR) by a coronary artery angioscope and establish intravascular visualization of SG. The patient was a 70-year-old woman with the distal aortic arch aneurysm and the descending aortic aneurysm, and debranching TEVAR were performed. After 12 months follow up, urgent hospitalization was required for chest pain, and cardiac catheter examination with a coronary artery angioscope was performed. The endoluminal SG was observed. The observation in angioscope which is a video image is better than CT that is a still image, and observation in blood vessel or SG is possible. It may be possible to observe the endoluminal SG, allowing potential investigation of an endoleak, or the covering status of the SG with the native aortic vessel wall, or the state of intimal membrane formation in the endoluminal graft.展开更多
文摘目的:探讨盐酸沙格雷酯治疗下肢动脉硬化闭塞症(arteriosclerotic obliterans,ASO)支架置入术后患者的疗效。方法:2008年6月至2009年10月,共52例因ASO而行下肢动脉支架置入术的患者,共57条患肢,随机分成两组,治疗组(26例,29条患肢)给予盐酸沙格雷酯100mg/次,3次/d,口服,对照组(26例,28条患肢)给予胰激肽原酶肠溶片120U,3次/d,口服。治疗6个月后从患者症状、跛行距离(distance of claudication,DOC)、踝肱指数(ankle/brachial index,ABI)、经皮氧分压(transcutaneousoxygen pressure,TcPO2)、支架再狭窄率、药物不良反应等方面判断治疗效果。结果:和对照组相比,治疗组术前ABI、TcPO2及DOC差异无统计学意义(P>0.05);术后2 w ABI、TcPO2差异无统计学意义(P>0.05);术后6个月ABI差异无统计学意义(P>0.05),TcPO2及DOC均改善,差异有统计学意义(P<0.05);治疗组主观感觉症状改善者25例,出现支架再狭窄1例,对照组主观感觉改善者22例,支架再狭窄3例,两者差异无统计学意义(P>0.05);治疗组支架两组术后用药未见明显不良反应。结论:盐酸沙格雷酯用于ASO支架置入术后治疗效果明确,安全、方便,值得推广。
文摘We could observe the endoluminal stent graft (SG) following thoracic endovascular aneurysm repair (TEVAR) by a coronary artery angioscope and establish intravascular visualization of SG. The patient was a 70-year-old woman with the distal aortic arch aneurysm and the descending aortic aneurysm, and debranching TEVAR were performed. After 12 months follow up, urgent hospitalization was required for chest pain, and cardiac catheter examination with a coronary artery angioscope was performed. The endoluminal SG was observed. The observation in angioscope which is a video image is better than CT that is a still image, and observation in blood vessel or SG is possible. It may be possible to observe the endoluminal SG, allowing potential investigation of an endoleak, or the covering status of the SG with the native aortic vessel wall, or the state of intimal membrane formation in the endoluminal graft.
