目的了解脑卒中患者的自测健康状况及其人口统计学的影响因素,为促进脑卒中患者的心理康复治疗提供参考依据。方法应用自测健康评定量表(self-rated health measurement scale version1.0,SRHMS),在调查员的现场指导下采用自主填写方式...目的了解脑卒中患者的自测健康状况及其人口统计学的影响因素,为促进脑卒中患者的心理康复治疗提供参考依据。方法应用自测健康评定量表(self-rated health measurement scale version1.0,SRHMS),在调查员的现场指导下采用自主填写方式对206名脑卒中患者进行调查。结果 1脑卒中患者生理健康(BZT)、心理健康(MZT)、社会健康(SZT)、自测健康总得分(ZCZT)均显著低于国内常模水平(P<0.001);既往有无卒中史及高血压病史的患者BZT、MZT、SZT、ZCZT存在显著差异(P<0.01);经济贫困与非贫困者BZT、MZT、SZT、ZCZT存在明显差异(P<0.05);有宗教信仰与无宗教信仰的患者MZT、SZT及ZCZT存在明显差异(P<0.05),而BZT差异无统计学意义(P>0.05);不同性别、年龄、婚姻状态、文化程度脑卒中患者的SRHMS得分差异均无统计学意义(P>0.05)。2PearSon及多因素线性回归分析显示,既往卒中史、宗教信仰、经济状况是SRHMS得分的相关影响因素(P<0.05)。结论脑卒中患者的自测健康状况明显偏差,既往有卒中病史、贫困、有宗教信仰是脑卒中患者自测健康的主要影响因素。展开更多
Purpose： We conducted an empirical study to find out the role of demographic variables in affecting information sharing behaviors of college student users of WeChat.Design/methodology/approach： A questionnaire surve...Purpose： We conducted an empirical study to find out the role of demographic variables in affecting information sharing behaviors of college student users of WeChat.Design/methodology/approach： A questionnaire survey was carried out to investigate the relationship between demographic variables （gender, grade level, dating status, and singleparent family background） and information sharing behaviors of WeChat users. The participants were college students and a total of 255 valid questionnaires were collected. Data was analyzed using descriptive statistics and multiple regression analysis.Findings： Grade level and single-parent family background were found to be significantly correlated with information sharing behaviors whereas no effect of gender was found on information sharing behaviors. Dating status had no significant impact on user browsing behavior, but was related to users＇ publishing posts and posting replies.Implications： The study will help understand individual differences in information sharing among WeChat users.Limitations： First, the relatively small sample size is a limitation in exploring the effects of demographic variables on user information sharing behaviors. Second, this study only used questionnaire surveys to collect data and more research methods such as interviews should be adopted to improve the accuracy of the study results.Originality/value： This paper is one of the first studies to explore the relationship between demographic variables and user information sharing behaviors on WeChat.展开更多
Background: Autosomal dominant polycystic kidney disease (ADPKD) is an important etiological factor causing chronic kidney disease (CKD), cardiovascular diseases and hypertension (HT). The purpose of the present study...Background: Autosomal dominant polycystic kidney disease (ADPKD) is an important etiological factor causing chronic kidney disease (CKD), cardiovascular diseases and hypertension (HT). The purpose of the present study is to investigate the clinical information and demographic characteristics of autosomal dominant polycystic kidney disease patients who received treatment at our hospital for the last five years. Material and Method: Among 21400 people who sought care at Siirt State Hospital Urology and Nephrology Outpatient Clinics between January 2015 and January 2020 for various reasons, a total of 36 patients experiencing autosomal dominant polycystic kidney disease were included in the present research. Retrospective patient file access was used to gather demographic information and laboratory data. Results: The study included 36 patients in all, 25 (69.4%) male and 11 (30.6%) female. The patient’s average age was 50.8 ± 19.0. The average age at diagnosis was 43.4 ± 17.2. Family history was positive in 29 (80.5%) of the patients. There were hypertension in 27 (75.0%) patients, coronary artery disease in five (13.9%) patients, diabetes mellitus in five (13.9%) patients, left ventricular hypertrophy in 18 (50%) patients, proteinuria in 11 (30.6%) patients, and six (16.7%) patients had macroscopic hematuria. Liver cysts were found in 23 (63.9%) of the patients and nephrolithiasis in eight (22.2%). Discussion: Hypertension is the most common finding when clinical and demographic data of autosomal dominant polycystic kidney disease are examined. Providing blood pressure control reduces the risk of death due to left ventricular hypertrophy and slows down the rate at which chronic kidney disease progresses. The rate was found to be 80.5% for patients with a positive family history. It may be possible to diagnose and treat people with autosomal dominant polycystic kidney disease earlier by screening their family members.展开更多
Alzheimer＇s disease （AD） remains to be a grand challenge for the international community despite over a century of exploration. A key factor likely accounting for such a situation is the vast heterogeneity in the d...Alzheimer＇s disease （AD） remains to be a grand challenge for the international community despite over a century of exploration. A key factor likely accounting for such a situation is the vast heterogeneity in the disease etiology, which involves very complex and divergent pathways. Therefore, intervention strategies shall be tailored for subgroups of AD patients. Both demographic and in-depth information is needed for patient stratification. The demographic information includes primarily APOE genotype, age, gender, education, environmental exposure, life style, and medical history, whereas in-depth information stems from genome sequencing, brain imaging, peripheral biomarkers, and even functional assays on neurons derived from patient-specific induced pluripotent cells （iPSCs）. Comprehensive information collection, better understanding of the disease mech- anisms, and diversified strategies of drug development would help with more effective intervention in the foreseeable future.展开更多
基金jointly supported by the National Social Science Foundation of China(Grant No.:14BTQ044)Wuhan University Academic Development Plan for Scholars born after the 1970s for the project of"research on Internet user behavior"Wuhan University Postgraduate English Course on Internet User Behavior and Luo Jia Youth Scholar of Wuhan University
文摘Purpose： We conducted an empirical study to find out the role of demographic variables in affecting information sharing behaviors of college student users of WeChat.Design/methodology/approach： A questionnaire survey was carried out to investigate the relationship between demographic variables （gender, grade level, dating status, and singleparent family background） and information sharing behaviors of WeChat users. The participants were college students and a total of 255 valid questionnaires were collected. Data was analyzed using descriptive statistics and multiple regression analysis.Findings： Grade level and single-parent family background were found to be significantly correlated with information sharing behaviors whereas no effect of gender was found on information sharing behaviors. Dating status had no significant impact on user browsing behavior, but was related to users＇ publishing posts and posting replies.Implications： The study will help understand individual differences in information sharing among WeChat users.Limitations： First, the relatively small sample size is a limitation in exploring the effects of demographic variables on user information sharing behaviors. Second, this study only used questionnaire surveys to collect data and more research methods such as interviews should be adopted to improve the accuracy of the study results.Originality/value： This paper is one of the first studies to explore the relationship between demographic variables and user information sharing behaviors on WeChat.
文摘Background: Autosomal dominant polycystic kidney disease (ADPKD) is an important etiological factor causing chronic kidney disease (CKD), cardiovascular diseases and hypertension (HT). The purpose of the present study is to investigate the clinical information and demographic characteristics of autosomal dominant polycystic kidney disease patients who received treatment at our hospital for the last five years. Material and Method: Among 21400 people who sought care at Siirt State Hospital Urology and Nephrology Outpatient Clinics between January 2015 and January 2020 for various reasons, a total of 36 patients experiencing autosomal dominant polycystic kidney disease were included in the present research. Retrospective patient file access was used to gather demographic information and laboratory data. Results: The study included 36 patients in all, 25 (69.4%) male and 11 (30.6%) female. The patient’s average age was 50.8 ± 19.0. The average age at diagnosis was 43.4 ± 17.2. Family history was positive in 29 (80.5%) of the patients. There were hypertension in 27 (75.0%) patients, coronary artery disease in five (13.9%) patients, diabetes mellitus in five (13.9%) patients, left ventricular hypertrophy in 18 (50%) patients, proteinuria in 11 (30.6%) patients, and six (16.7%) patients had macroscopic hematuria. Liver cysts were found in 23 (63.9%) of the patients and nephrolithiasis in eight (22.2%). Discussion: Hypertension is the most common finding when clinical and demographic data of autosomal dominant polycystic kidney disease are examined. Providing blood pressure control reduces the risk of death due to left ventricular hypertrophy and slows down the rate at which chronic kidney disease progresses. The rate was found to be 80.5% for patients with a positive family history. It may be possible to diagnose and treat people with autosomal dominant polycystic kidney disease earlier by screening their family members.
基金supported by the National High-tech R&D Program of China (863 ProgramGrant No.2015AA020108)+1 种基金the National Basic Research Program of China (973 ProgramGrant No.2014CB964901) funded by the Ministry of Science and Technology of China
文摘Alzheimer＇s disease （AD） remains to be a grand challenge for the international community despite over a century of exploration. A key factor likely accounting for such a situation is the vast heterogeneity in the disease etiology, which involves very complex and divergent pathways. Therefore, intervention strategies shall be tailored for subgroups of AD patients. Both demographic and in-depth information is needed for patient stratification. The demographic information includes primarily APOE genotype, age, gender, education, environmental exposure, life style, and medical history, whereas in-depth information stems from genome sequencing, brain imaging, peripheral biomarkers, and even functional assays on neurons derived from patient-specific induced pluripotent cells （iPSCs）. Comprehensive information collection, better understanding of the disease mech- anisms, and diversified strategies of drug development would help with more effective intervention in the foreseeable future.
