The convection structure in a rectangular channel with a horizontal flow forΓ = 12 was studied. The simulations were preformed by solving the hydrodynamic equations using theSIMPLE method. The convective behavior in ...The convection structure in a rectangular channel with a horizontal flow forΓ = 12 was studied. The simulations were preformed by solving the hydrodynamic equations using theSIMPLE method. The convective behavior in an absolutely and convectively unstable regime wasstudied. The results show that the two types of convection patterns in this system appear dependingon the convection intensity and horizontal flow. A periodically localized traveling wave state wasfound in this system.展开更多
An experimental investigation is described for the characteristics of convective boiling flow instabilities in horizontally helically coiled tubes using a steam-water two-phase closed circulation test loop at pressure...An experimental investigation is described for the characteristics of convective boiling flow instabilities in horizontally helically coiled tubes using a steam-water two-phase closed circulation test loop at pressure from 0.5 MPa to 3.5 MPa. Three kinds of oscillation are reported: density waves; pressure drop excursions; thermal fluctuations. We describe their dependence on main system parameters such as system pressure, mass flowrate, inlet subcooling, compressible volume and heat flux. Utilizing the experimental data together with conservation constraints, a dimensionless correlation is proposed for the occurrence of density waves.展开更多
The aims of this study were to investigate the utility of solid microneedle arrays(150 mm in length)in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D_...The aims of this study were to investigate the utility of solid microneedle arrays(150 mm in length)in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D_(2)O flux.Four model peptides were used(Gly-Gln-Pro-Arg[tetrapeptide-3,456.6 Da],Val-Gly-Val-Ala-Pro-Gly[hexapeptide,498.6 Da],AC-Glu-Glu-Met-Gln-Arg-Arg-NH2[acetyl hexapeptide-3,889 Da]and Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2[oxytocin,1007.2 Da]).The influence of microneedle pretreat-ment on skin permeation was evaluated using porcine ear skin with Franze diffusion cell.Peptide permeation across the skin was significantly enhanced by microneedle pretreatment,and permeation rates were dependent on peptide molecular weights.A positive correlation between D_(2)O flux and acetyl hexapeptide-3 clearances suggests that convective solvent flow contributes to the enhanced transdermal peptide delivery.It is concluded that solid microneedle arrays are effective devices to enhance skin delivery of peptides.展开更多
Oxidation of organic pollutants by sulfate radicals produced via activation of persulfate has emerged as a promising advanced oxidation technology to address various challenging environmental issues. The development o...Oxidation of organic pollutants by sulfate radicals produced via activation of persulfate has emerged as a promising advanced oxidation technology to address various challenging environmental issues. The development of an effective, environmentally-friendly, metal-free catalyst is the key to this technology. Additionally, a supported catalyst design is more advantageous than conventional suspended powder catalysts from the point of view of mass transfer and practical engineering applications （e.g. post-use separation）. In this study, a metal-free N-doped reduced graphene oxide （N-rGO） catalyst was prepared via a facile hydrothermal method. N-rGO filters were then synthesized by facile vacuum filtration, such that water can flow through nanochannels within the filters. Various advanced characterization techniques were employed to obtain structural and compositional information of the as-synthesized N-rGO filters. An optimized phenol oxidative flux of 0.036 ＋_ 0.002 mmol.h ~ was obtained by metal-flee catalytic activation of persulfate at an influent persulfate concentration of 1.0 mmol-L 1 and filter weight of 15 rag, while a N-free rGO filter demonstrated negligible phenol oxidation capability under similar conditions. Compared to a conventional batch system, the flow-through design demonstrates obviously enhanced oxidation kinetics （0.036 vs. 0.010 retool-h-I）, mainly due to the liquid flow through the filter leading to convection-enhanced transfer of the target molecule to the filter active sites. Overall, the results exemplified the advantages of organic compound removal by catalytic activation of persulfate using a metal-free catalyst in flow- through mode, and demonstrated the potential of N-rGO filters for practical environmental applications.展开更多
Hydrostatic spindles are increasingly used in precision machine tools. Thermal error is the key factor affecting the machining accuracy of the spindle, and research has focused on spindle thermal errors through examin...Hydrostatic spindles are increasingly used in precision machine tools. Thermal error is the key factor affecting the machining accuracy of the spindle, and research has focused on spindle thermal errors through examination of the influence of the temperature distribution, thermal deformation and spindle mode. However, seldom has any research investigated the thermal effects of the associated Couette flow. To study the heat transfer mechanism in spindle systems, the criterion of the heat transfer direction according to the temperature distribution of the Couette flow at different temperatures is deduced. The method is able to deal accurately with the significant phenomena occurring at every place where thermal energy flowed in such a spindle system. The variation of the motion error induced by thermal effects on a machine work-table during machining is predicated by establishing the thermo-mechanical error model of the hydrostatic spindle for a high precision machine tool. The flow state and thermal behavior of a hydrostatic spindle is analyzed with the evaluated heat power and the coefficients of the convective heat transfer over outer surface of the spindle are calculated, and the thermal influence on the oil film stiffness is evaluated. Thermal drift of the spindle nose is measured with an inductance micrometer, the thermal deformation data 1.35 μm after running for 4 h is consistent with the value predicted by the finite element analysis’s simulated result 1.28 μm, and this demonstrates that the simulation method is feasible. The thermal effects on the processing accuracy from the flow characteristics of the fluid inside the spindle are analyzed for the first time.展开更多
A compressible lattice Boltzmann-finite difference method is extended by the phase-field approach into a monolithic scheme to study fluid flow and heat transfer through regular arrangements of solid bodies of circular...A compressible lattice Boltzmann-finite difference method is extended by the phase-field approach into a monolithic scheme to study fluid flow and heat transfer through regular arrangements of solid bodies of circular,elliptical and irregular shapes.The advantage of using the phase-field method is demon-strated both in its simplicity of accounting for flow and thermal boundary conditions at solid surfaces with irregular shapes and in the capability of generating such complex-shaped objects.For an array of discs,numerical results for the overall solid-to-gas heat transfer rate are validated via experiments on flow through arrays of hot cylinders.The thus validated compressible LB-FD-PF hybrid scheme is used to study the dependence of heat transfer on flow and thermal boundary conditions(Reynolds number,temperature difference between the hot solid bodies and the inlet gas),porosity as well as on the shape of solid objects.Results are rationalized in terms of the residence time of the gas close to the solid body and downstream variations of gas velocity and temperature.Perspective for further applications of the proposed methodology are also discussed.展开更多
In this article, mathematical modeling for peristaltic flow of Rabinowitsch fluid model is considered in a non-uniform tube with combined effects of viscous dissipation and convective boundary conditions. Wall propert...In this article, mathematical modeling for peristaltic flow of Rabinowitsch fluid model is considered in a non-uniform tube with combined effects of viscous dissipation and convective boundary conditions. Wall properties analysis is also taken into account. Non-dimensional differential equations are simplified by using the well-known assumptions of low Reynolds number and long wavelength. The influence of various parameters connected with this flow problem such as rigidity parameter E1, stiffness parameter E2, viscous damping force parameter E3, Brickman number and Biot number are plotted for velocity distribution, temperature profile and for stream function. Results are plotted and discussed in detail for shear thinning, shear thickening and for viscous fluid. It is found that velocity profile is an increasing function of rigidity parameter, stiffness parameter, and viscous damping force parameter for shear thinning and for viscous fluid, due to the less resistance offered by the walls but, quite opposite behavior is depicted for shear thickening fluids. It is seen that Brickman number relates to the viscous dissipation effects, so it contributes in enhancing fluid temperature for all cases.展开更多
Heat and mass transfer of a circular-shaped porous moist object inside a two-dimensional triangle cavity is investigated by using finite element method.The porous object is considered to be a moist food sample,located...Heat and mass transfer of a circular-shaped porous moist object inside a two-dimensional triangle cavity is investigated by using finite element method.The porous object is considered to be a moist food sample,located in the middle of the cavity with inlet and outlet ports with different configurations of inlet/outlet ports.Convective drying performance is numerically assessed for different values of Reynolds numbers(between 50 and 250),dry air inlet temperature(between 40 and 80℃)and different locations of the port.It is observed that changing the port locations has significant impacts on the flow recirculaitons inside the triangular chamber while convective drying performance is highly affected.The moisture content reduces with longer time and for higher Reynolds number(Re)values.Case P4 where inlet and outlet ports are in the middle of the walls provides the most effective configuration in terms of convective drying performance while the worst case is seen for P1 case where inlet and outlet are closer to the corners of the chamber.There is a 192% difference between the moisture reduction of these two cases at Re=250,T=80℃ and t=120 min.展开更多
The growth model of a spherical crystal in the undercooled melt including the surface energy, interfacial kinetics and convective flow is established. The effect of the convective flow induced by a small far field flo...The growth model of a spherical crystal in the undercooled melt including the surface energy, interfacial kinetics and convective flow is established. The effect of the convective flow induced by a small far field flow on the evolution and morphological stability of the interface of the spherical crystal is studied. The interface shape of the spherical crystal, which is affected by the far field flow, and the dispersion relation of the growth rate of amplitude of the perturbed interface are derived. It is shown that the convection induced by the far field flow makes the interface of the growing spherical crystal further grow in the upstream direction of the far field flow and inhibit growth in the downstream direction; the interface of the decaying spherical crystal further decays in the upstream direction and inhibits decay in the downstream direction. The theoretical result suggests that both the growth of the sphere in the upstream direction and the decay of the sphere in the downstream direction make the spherical crystal tend to evolve into an oval; the morphological stability of the interface depends on a certain radius R c such that the spherical crystal is unstable when its radius is greater than R c and stable when its radius is less than R c . The surface energy and interfacial kinetics have strong stabilizing effects on the growth of the spherical crystal. In the meantime interfacial kinetics is a table factor of the interface when the interface of the sphere is growing; it is an unstable factor of the interface when the interface is decaying.展开更多
文摘The convection structure in a rectangular channel with a horizontal flow forΓ = 12 was studied. The simulations were preformed by solving the hydrodynamic equations using theSIMPLE method. The convective behavior in an absolutely and convectively unstable regime wasstudied. The results show that the two types of convection patterns in this system appear dependingon the convection intensity and horizontal flow. A periodically localized traveling wave state wasfound in this system.
文摘2008年7月13-14日郑州市出现局地大暴雨,24 h降雨量达174 mm,为1951年以来第二高值。这次大暴雨主要由两个时段的强降水累计而成,具有明显的中尺度特征。通过对常规气象资料分析发现:第一时段的强降水由副热带高压内部产生的局地对流云团加强造成,对流层底层东风气流的加强提供的水汽输送和动力抬升作用,促进了对流发展;新生云团进入潮湿的大气环境中能够得到迅速的发展。针对降水具有的明显中尺度特征,综合分析卫星、雷达、自动站等资料发现:利用新一代天气雷达的组合风廓线拼图可以很好地监测中尺度系统的演变趋势;区域自动站的10 m in极大风速场上显示,地面中尺度辐合线和郑州附近的气旋中心维持时段,与对流云团影响郑州及强降水时段对应。因此具有中尺度特征的局地强降水,可由雷达、自动站等信息作出短时临近预报。
文摘An experimental investigation is described for the characteristics of convective boiling flow instabilities in horizontally helically coiled tubes using a steam-water two-phase closed circulation test loop at pressure from 0.5 MPa to 3.5 MPa. Three kinds of oscillation are reported: density waves; pressure drop excursions; thermal fluctuations. We describe their dependence on main system parameters such as system pressure, mass flowrate, inlet subcooling, compressible volume and heat flux. Utilizing the experimental data together with conservation constraints, a dimensionless correlation is proposed for the occurrence of density waves.
文摘The aims of this study were to investigate the utility of solid microneedle arrays(150 mm in length)in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D_(2)O flux.Four model peptides were used(Gly-Gln-Pro-Arg[tetrapeptide-3,456.6 Da],Val-Gly-Val-Ala-Pro-Gly[hexapeptide,498.6 Da],AC-Glu-Glu-Met-Gln-Arg-Arg-NH2[acetyl hexapeptide-3,889 Da]and Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2[oxytocin,1007.2 Da]).The influence of microneedle pretreat-ment on skin permeation was evaluated using porcine ear skin with Franze diffusion cell.Peptide permeation across the skin was significantly enhanced by microneedle pretreatment,and permeation rates were dependent on peptide molecular weights.A positive correlation between D_(2)O flux and acetyl hexapeptide-3 clearances suggests that convective solvent flow contributes to the enhanced transdermal peptide delivery.It is concluded that solid microneedle arrays are effective devices to enhance skin delivery of peptides.
文摘Oxidation of organic pollutants by sulfate radicals produced via activation of persulfate has emerged as a promising advanced oxidation technology to address various challenging environmental issues. The development of an effective, environmentally-friendly, metal-free catalyst is the key to this technology. Additionally, a supported catalyst design is more advantageous than conventional suspended powder catalysts from the point of view of mass transfer and practical engineering applications （e.g. post-use separation）. In this study, a metal-free N-doped reduced graphene oxide （N-rGO） catalyst was prepared via a facile hydrothermal method. N-rGO filters were then synthesized by facile vacuum filtration, such that water can flow through nanochannels within the filters. Various advanced characterization techniques were employed to obtain structural and compositional information of the as-synthesized N-rGO filters. An optimized phenol oxidative flux of 0.036 ＋_ 0.002 mmol.h ~ was obtained by metal-flee catalytic activation of persulfate at an influent persulfate concentration of 1.0 mmol-L 1 and filter weight of 15 rag, while a N-free rGO filter demonstrated negligible phenol oxidation capability under similar conditions. Compared to a conventional batch system, the flow-through design demonstrates obviously enhanced oxidation kinetics （0.036 vs. 0.010 retool-h-I）, mainly due to the liquid flow through the filter leading to convection-enhanced transfer of the target molecule to the filter active sites. Overall, the results exemplified the advantages of organic compound removal by catalytic activation of persulfate using a metal-free catalyst in flow- through mode, and demonstrated the potential of N-rGO filters for practical environmental applications.
基金supported by National Natural Science Foundation of China (Grant Nos. 51105005, 51275014)Ministry of Education of China (Grant No. 20111103120002)
文摘Hydrostatic spindles are increasingly used in precision machine tools. Thermal error is the key factor affecting the machining accuracy of the spindle, and research has focused on spindle thermal errors through examination of the influence of the temperature distribution, thermal deformation and spindle mode. However, seldom has any research investigated the thermal effects of the associated Couette flow. To study the heat transfer mechanism in spindle systems, the criterion of the heat transfer direction according to the temperature distribution of the Couette flow at different temperatures is deduced. The method is able to deal accurately with the significant phenomena occurring at every place where thermal energy flowed in such a spindle system. The variation of the motion error induced by thermal effects on a machine work-table during machining is predicated by establishing the thermo-mechanical error model of the hydrostatic spindle for a high precision machine tool. The flow state and thermal behavior of a hydrostatic spindle is analyzed with the evaluated heat power and the coefficients of the convective heat transfer over outer surface of the spindle are calculated, and the thermal influence on the oil film stiffness is evaluated. Thermal drift of the spindle nose is measured with an inductance micrometer, the thermal deformation data 1.35 μm after running for 4 h is consistent with the value predicted by the finite element analysis’s simulated result 1.28 μm, and this demonstrates that the simulation method is feasible. The thermal effects on the processing accuracy from the flow characteristics of the fluid inside the spindle are analyzed for the first time.
基金funded by the Deutsche For-schungsgemeinschaft(DFG,German Research Foundation)-422037413-CRC/TRR 287"BULK-REACTION".
文摘A compressible lattice Boltzmann-finite difference method is extended by the phase-field approach into a monolithic scheme to study fluid flow and heat transfer through regular arrangements of solid bodies of circular,elliptical and irregular shapes.The advantage of using the phase-field method is demon-strated both in its simplicity of accounting for flow and thermal boundary conditions at solid surfaces with irregular shapes and in the capability of generating such complex-shaped objects.For an array of discs,numerical results for the overall solid-to-gas heat transfer rate are validated via experiments on flow through arrays of hot cylinders.The thus validated compressible LB-FD-PF hybrid scheme is used to study the dependence of heat transfer on flow and thermal boundary conditions(Reynolds number,temperature difference between the hot solid bodies and the inlet gas),porosity as well as on the shape of solid objects.Results are rationalized in terms of the residence time of the gas close to the solid body and downstream variations of gas velocity and temperature.Perspective for further applications of the proposed methodology are also discussed.
文摘In this article, mathematical modeling for peristaltic flow of Rabinowitsch fluid model is considered in a non-uniform tube with combined effects of viscous dissipation and convective boundary conditions. Wall properties analysis is also taken into account. Non-dimensional differential equations are simplified by using the well-known assumptions of low Reynolds number and long wavelength. The influence of various parameters connected with this flow problem such as rigidity parameter E1, stiffness parameter E2, viscous damping force parameter E3, Brickman number and Biot number are plotted for velocity distribution, temperature profile and for stream function. Results are plotted and discussed in detail for shear thinning, shear thickening and for viscous fluid. It is found that velocity profile is an increasing function of rigidity parameter, stiffness parameter, and viscous damping force parameter for shear thinning and for viscous fluid, due to the less resistance offered by the walls but, quite opposite behavior is depicted for shear thickening fluids. It is seen that Brickman number relates to the viscous dissipation effects, so it contributes in enhancing fluid temperature for all cases.
文摘Heat and mass transfer of a circular-shaped porous moist object inside a two-dimensional triangle cavity is investigated by using finite element method.The porous object is considered to be a moist food sample,located in the middle of the cavity with inlet and outlet ports with different configurations of inlet/outlet ports.Convective drying performance is numerically assessed for different values of Reynolds numbers(between 50 and 250),dry air inlet temperature(between 40 and 80℃)and different locations of the port.It is observed that changing the port locations has significant impacts on the flow recirculaitons inside the triangular chamber while convective drying performance is highly affected.The moisture content reduces with longer time and for higher Reynolds number(Re)values.Case P4 where inlet and outlet ports are in the middle of the walls provides the most effective configuration in terms of convective drying performance while the worst case is seen for P1 case where inlet and outlet are closer to the corners of the chamber.There is a 192% difference between the moisture reduction of these two cases at Re=250,T=80℃ and t=120 min.
基金Supported by the National Basic Research Program of China (Grant No. 2006CB605205)the National Natural Science Foundation of China (Grant Nos. 10672019 and 10572062)the Science and Technology Foundation of Shanghai (Grant No. 055207081)
文摘The growth model of a spherical crystal in the undercooled melt including the surface energy, interfacial kinetics and convective flow is established. The effect of the convective flow induced by a small far field flow on the evolution and morphological stability of the interface of the spherical crystal is studied. The interface shape of the spherical crystal, which is affected by the far field flow, and the dispersion relation of the growth rate of amplitude of the perturbed interface are derived. It is shown that the convection induced by the far field flow makes the interface of the growing spherical crystal further grow in the upstream direction of the far field flow and inhibit growth in the downstream direction; the interface of the decaying spherical crystal further decays in the upstream direction and inhibits decay in the downstream direction. The theoretical result suggests that both the growth of the sphere in the upstream direction and the decay of the sphere in the downstream direction make the spherical crystal tend to evolve into an oval; the morphological stability of the interface depends on a certain radius R c such that the spherical crystal is unstable when its radius is greater than R c and stable when its radius is less than R c . The surface energy and interfacial kinetics have strong stabilizing effects on the growth of the spherical crystal. In the meantime interfacial kinetics is a table factor of the interface when the interface of the sphere is growing; it is an unstable factor of the interface when the interface is decaying.
