对3例先天性胆管扩张症合并胆管结石,利用 X 线衍射仪及红外线吸收光谱仪检测结石样品,发现3例结石成分基本一致,结晶程度极好,晶态物质的主要成分为柠檬酸钙、硬脂酸钙。结石属特殊型结石。作者认为,结石成因可能与胰胆管合流异常、胰...对3例先天性胆管扩张症合并胆管结石,利用 X 线衍射仪及红外线吸收光谱仪检测结石样品,发现3例结石成分基本一致,结晶程度极好,晶态物质的主要成分为柠檬酸钙、硬脂酸钙。结石属特殊型结石。作者认为,结石成因可能与胰胆管合流异常、胰液返流、胰脂肪酶被激活有关。同时对比观察2例遗传性球形细胞增多症合并胆囊结石的成分、类型与前者不同。指出胰胆管合流异常、胰液返流在结石形成过程中的作用值得重视。展开更多
Objective To observe the effect of serum trace elements in congenital bile duct dilatation.Methods The trace elements of serum including Cu, Zn, Fe, Ca and Mg were measured in sixty-six cases of congenital bile duct d...Objective To observe the effect of serum trace elements in congenital bile duct dilatation.Methods The trace elements of serum including Cu, Zn, Fe, Ca and Mg were measured in sixty-six cases of congenital bile duct dilatation.Results The concentrations of total bilirubin and direct reacting bilirubin in blood were higher than normal.The concentration of blood bilirubin was positive correlation to the concentration of serum Cu(r=0 4682,P<0 05) and was negative correlation to the concentration of serum Zn(r=-0 6023,P<0 01).The concentration of serum Zinc before operation was significantly lower than that after operation(P<0 05).The concentration of serum Cu before operation was significantly higher than that after operation(P<0 01).Conclusion The concentrations of serum Cu and Zn can imply the extents of cholestasis and hepatic injury.展开更多
文摘对3例先天性胆管扩张症合并胆管结石,利用 X 线衍射仪及红外线吸收光谱仪检测结石样品,发现3例结石成分基本一致,结晶程度极好,晶态物质的主要成分为柠檬酸钙、硬脂酸钙。结石属特殊型结石。作者认为,结石成因可能与胰胆管合流异常、胰液返流、胰脂肪酶被激活有关。同时对比观察2例遗传性球形细胞增多症合并胆囊结石的成分、类型与前者不同。指出胰胆管合流异常、胰液返流在结石形成过程中的作用值得重视。
文摘目的:探讨内镜逆行胰胆管造影(endoscopic retrograde cholangiopancreatography, ERCP)在诊断和治疗小儿胰胆管汇合异常(pancreaticobiliary maljunction, PBM)中的安全性和有效性。方法:回顾性分析本院ERCP确诊为PBM的74例患儿,分析临床资料和术后随访。结果 :按照日本胆胰管合流异常研究组(Japanese Study Group on Pancreaticobiliary Maljunction, JSGPM)分型,A型32例,B型16例,C型23例,D型3例。MRCP检查的阳性诊断率仅8%。本研究所有患儿均行乳头肌切开和鼻胆管引流。其中69例(93.4%)行取石/蛋白酶栓,2例术后留置胰管支架。7例(9.5%)术后出现ERCP后轻型胰腺炎,无术后出血、贲门撕裂及穿孔等严重并发症发生。除7例(9.5%)PBM不合并胆道扩张的患儿外,其余术后均行肝外胆管切除+肝管空肠Roux-en-Y吻合术。结论:ERCP在小儿PBM的诊治过程中具有诊断效力强、疗效好、安全性高的优点,对早期确诊并干预PBM的病理进程具有重要意义。
文摘Objective To observe the effect of serum trace elements in congenital bile duct dilatation.Methods The trace elements of serum including Cu, Zn, Fe, Ca and Mg were measured in sixty-six cases of congenital bile duct dilatation.Results The concentrations of total bilirubin and direct reacting bilirubin in blood were higher than normal.The concentration of blood bilirubin was positive correlation to the concentration of serum Cu(r=0 4682,P<0 05) and was negative correlation to the concentration of serum Zn(r=-0 6023,P<0 01).The concentration of serum Zinc before operation was significantly lower than that after operation(P<0 05).The concentration of serum Cu before operation was significantly higher than that after operation(P<0 01).Conclusion The concentrations of serum Cu and Zn can imply the extents of cholestasis and hepatic injury.
