Conducting polymers offer attractive mixed ionic-electronic conductivity,tunable interfacial barrier with metal,tissue matchable softness,and versatile chemical functionalization,making them robust to bridge the gap b...Conducting polymers offer attractive mixed ionic-electronic conductivity,tunable interfacial barrier with metal,tissue matchable softness,and versatile chemical functionalization,making them robust to bridge the gap between brain tissue and electronic circuits.This review focuses on chemically revised conducting polymers,combined with their superior and controllable electrochemical performance,to fabricate long-term bioelectronic implants,addressing chronic immune responses,weak neuron attraction,and long-term electrocommunication instability challenges.Moreover,the promising progress of zwitterionic conducting polymers in bioelectronic implants(≥4 weeks stable implantation)is highlighted,followed by a comment on their current evolution toward selective neural coupling and reimplantable function.Finally,a critical forward look at the future of zwitterionic conducting polymers for in vivo bioelectronic devices is provided.展开更多
Water soluble conducting polyaniline with electrical conductivity of 10^(-1)-10^(-2) S/cm was prepared employingdopant induced water solubility technology. The water resistance of the conducting film was significantly...Water soluble conducting polyaniline with electrical conductivity of 10^(-1)-10^(-2) S/cm was prepared employingdopant induced water solubility technology. The water resistance of the conducting film was significantly improvedemploying sol-gel hybrids method, especially when the conductive polyaniline loading was below 30 wt%. The reason forthe improvement is that the conducting polyaniline chains are confined in a stable inorganic network.展开更多
基金supported by NSFC(22175111,21474014,21704013,and 51903149)the Program for Professor of Special Appointment(Eastern Scholar)at the Shanghai Institutions of Higher Learning(TP2019043)the Program of Shanghai Academic/Technology Research Leader(20XD1400100).
文摘Conducting polymers offer attractive mixed ionic-electronic conductivity,tunable interfacial barrier with metal,tissue matchable softness,and versatile chemical functionalization,making them robust to bridge the gap between brain tissue and electronic circuits.This review focuses on chemically revised conducting polymers,combined with their superior and controllable electrochemical performance,to fabricate long-term bioelectronic implants,addressing chronic immune responses,weak neuron attraction,and long-term electrocommunication instability challenges.Moreover,the promising progress of zwitterionic conducting polymers in bioelectronic implants(≥4 weeks stable implantation)is highlighted,followed by a comment on their current evolution toward selective neural coupling and reimplantable function.Finally,a critical forward look at the future of zwitterionic conducting polymers for in vivo bioelectronic devices is provided.
基金This work was supported by the National Natural Science Foundation of China (Grant No. 29992535).
文摘Water soluble conducting polyaniline with electrical conductivity of 10^(-1)-10^(-2) S/cm was prepared employingdopant induced water solubility technology. The water resistance of the conducting film was significantly improvedemploying sol-gel hybrids method, especially when the conductive polyaniline loading was below 30 wt%. The reason forthe improvement is that the conducting polyaniline chains are confined in a stable inorganic network.
