An improved particle swarm optimization（PSO） algorithm is proposed to train the fuzzy support vector machine（FSVM） for pattern multi-classification.In the improved algorithm,the particles studies not only from its...An improved particle swarm optimization（PSO） algorithm is proposed to train the fuzzy support vector machine（FSVM） for pattern multi-classification.In the improved algorithm,the particles studies not only from itself and the best one but also from the mean value of some other particles.In addition,adaptive mutation was introduced to reduce the rate of premature convergence.The experimental results on the synthetic aperture radar（SAR） target recognition of moving and stationary target acquisition and recognition（MSTAR） dataset and character recognition of MNIST database show that the improved algorithm is feasible and effective for fuzzy multi-class SVM training.展开更多
Charcot-Marie-Tooth （CMT） disease is the most common inherited peripheral neuropathic disorder. CMT is clinically and genetically heterogeneous. To date, 27 genes associated with the disease have been cloned. The pr...Charcot-Marie-Tooth （CMT） disease is the most common inherited peripheral neuropathic disorder. CMT is clinically and genetically heterogeneous. To date, 27 genes associated with the disease have been cloned. The present study carried out clinical classification according to clinical, electrophysiological and pathological features, conducted inheritance classification according to inheritance patterns, and performed mutation analysis of 13 CMT disease genes （PMP22, CX32, HSPB1, MNF2, MPZ, HSPB8, GDAP1, NFL, EGR2, SIMPLE, RAB7, LMNA, MTMR2） in 57 Chinese probands with CMT. Five cases of AD-CMT1 and 13 cases of sporadic CMT1 were diagnosed as CMT1A; five cases of X-CMT1, one case of X-CMT2 and one case of sporadic CMT1 were diagnosed as CMTXl; four cases of AD-CMT2 were diagnosed as CMT2F; one case of AD-CMT2 and one case of sporadic CMT2 were diagnosed as CMT2A2; one case of AD-CMT2 was diagnosed as CMT2L; one case of AD-CMT2 was diagnosed as CMT2J; one case of AR-CMT1 was diagnosed as CMT4A. Among the 57 CMT probands, seven genotypes were determined among 34 patients, with a detection rate of 59.6%. The results indicated that the clinical classification and inheritance classification are indispensable for selecting potential disease genes for mutation detection, and for efficient molecular diagnosis.展开更多
颠覆性技术对实现中国科技创新跨越式发展具有重要战略意义。以无人机技术领域为例,获取Web of Science论文数据库和德温特(Derwent)专利数据库2005—2019年收录的2812篇论文与专利数据,基于LDA-LSTM文本分类算法得到技术主题,采用CiteS...颠覆性技术对实现中国科技创新跨越式发展具有重要战略意义。以无人机技术领域为例,获取Web of Science论文数据库和德温特(Derwent)专利数据库2005—2019年收录的2812篇论文与专利数据,基于LDA-LSTM文本分类算法得到技术主题,采用CiteSpace构建共现网络,从突变权重排序及突变时间段和突变共词聚类知识图谱2个角度进行主题突变检测,进而识别出无人机交互技术中的脑机接口技术及手势控制技术为该领域内的颠覆性技术,通过2020年无人机技术领域相关论文专利验证了识别框架的有效性。展开更多
基金supported by the National Natural Science Foundation of China (60873086)the Aeronautical Science Foundation of China(20085153013)the Fundamental Research Found of Northwestern Polytechnical Unirersity (JC200942)
文摘An improved particle swarm optimization（PSO） algorithm is proposed to train the fuzzy support vector machine（FSVM） for pattern multi-classification.In the improved algorithm,the particles studies not only from itself and the best one but also from the mean value of some other particles.In addition,adaptive mutation was introduced to reduce the rate of premature convergence.The experimental results on the synthetic aperture radar（SAR） target recognition of moving and stationary target acquisition and recognition（MSTAR） dataset and character recognition of MNIST database show that the improved algorithm is feasible and effective for fuzzy multi-class SVM training.
基金the National Natural Science Foundation of China, No. 81071001, 30600200the Natural Science Foundation of Hu-nan Province, No. 2006JJ30009
文摘Charcot-Marie-Tooth （CMT） disease is the most common inherited peripheral neuropathic disorder. CMT is clinically and genetically heterogeneous. To date, 27 genes associated with the disease have been cloned. The present study carried out clinical classification according to clinical, electrophysiological and pathological features, conducted inheritance classification according to inheritance patterns, and performed mutation analysis of 13 CMT disease genes （PMP22, CX32, HSPB1, MNF2, MPZ, HSPB8, GDAP1, NFL, EGR2, SIMPLE, RAB7, LMNA, MTMR2） in 57 Chinese probands with CMT. Five cases of AD-CMT1 and 13 cases of sporadic CMT1 were diagnosed as CMT1A; five cases of X-CMT1, one case of X-CMT2 and one case of sporadic CMT1 were diagnosed as CMTXl; four cases of AD-CMT2 were diagnosed as CMT2F; one case of AD-CMT2 and one case of sporadic CMT2 were diagnosed as CMT2A2; one case of AD-CMT2 was diagnosed as CMT2L; one case of AD-CMT2 was diagnosed as CMT2J; one case of AR-CMT1 was diagnosed as CMT4A. Among the 57 CMT probands, seven genotypes were determined among 34 patients, with a detection rate of 59.6%. The results indicated that the clinical classification and inheritance classification are indispensable for selecting potential disease genes for mutation detection, and for efficient molecular diagnosis.
文摘颠覆性技术对实现中国科技创新跨越式发展具有重要战略意义。以无人机技术领域为例,获取Web of Science论文数据库和德温特(Derwent)专利数据库2005—2019年收录的2812篇论文与专利数据,基于LDA-LSTM文本分类算法得到技术主题,采用CiteSpace构建共现网络,从突变权重排序及突变时间段和突变共词聚类知识图谱2个角度进行主题突变检测,进而识别出无人机交互技术中的脑机接口技术及手势控制技术为该领域内的颠覆性技术,通过2020年无人机技术领域相关论文专利验证了识别框架的有效性。
