背景:玻璃酸钠本身特殊的理化性质决定了其非常重要的生理作用,如构成细胞基质、润滑关节、促进组织损伤修复等。目的:观察玻璃酸钠注射治疗不同病程髌骨软化症的疗效。方法:76例髌骨软化症患者关节腔内注射玻璃酸钠2 m L(以髌骨内侧缘...背景:玻璃酸钠本身特殊的理化性质决定了其非常重要的生理作用,如构成细胞基质、润滑关节、促进组织损伤修复等。目的:观察玻璃酸钠注射治疗不同病程髌骨软化症的疗效。方法:76例髌骨软化症患者关节腔内注射玻璃酸钠2 m L(以髌骨内侧缘为进针点,每周1次,5周为1个疗程),根据病程分两组,病程<3个月32例,病程>3个月44例,随访1年观察远期疗效。结果与结论:随访1年发现病程<3个月组的优良率达94%,远期疗效优于病程>3个月组(优良率73%)。治疗期间无明显毒副作用,其中有5例注射后疼痛加重,可能与髌下积液未抽尽和早期穿刺技术不熟练有关,休息后一两天均得到缓解,未发生感染。结果可见玻璃酸钠是治疗髌骨软化症的有效药物,早期治疗及合理的进针点是保证疗效的关键。展开更多
OBJECTIVE: To evaluate the clinical effect of traditional Chinese spinal orthopedic manipulation(TCSOM) in treating chondromalacia patellae(CP).METHODS: Sixty cases of CP patients were randomly assigned to a TCSOM gro...OBJECTIVE: To evaluate the clinical effect of traditional Chinese spinal orthopedic manipulation(TCSOM) in treating chondromalacia patellae(CP).METHODS: Sixty cases of CP patients were randomly assigned to a TCSOM group and a Celecoxib group according to the random number table method. All patients in the TCSOM group were treated with a maximum of 10 spinal manipulations and rehabilitation training of quadriceps femoris. The symptoms before and after treatment were assessed with visual analog scale(VAS) and Kujala functional knee scoring system(KFKSS). A symptom improvement rate(SIR) was implemented in order to evaluate the effects of the treatments.RESULTS: The symptoms of 16 patients in the TC-SOM group quickly resolved after the first spinal manipulation and 8 cases were significantly improved. The VAS scores in the TCSOM group after 4weeks of treatment were significantly lower than those in the Celecoxib group. The KFKSS scores in the TCSOM group after 4 weeks of treatment were significantly higher than those in the Celecoxib group. Side effects of the treatment were not reported. Symptom improvement rate based on the VAS in the TCSOM group indicated more significant improvements than the Celecoxib group.CONCLUSION: TCSOM has greater efficacy than Celecoxib capsules for relief of the symptoms of CP.展开更多
文摘背景:玻璃酸钠本身特殊的理化性质决定了其非常重要的生理作用,如构成细胞基质、润滑关节、促进组织损伤修复等。目的:观察玻璃酸钠注射治疗不同病程髌骨软化症的疗效。方法:76例髌骨软化症患者关节腔内注射玻璃酸钠2 m L(以髌骨内侧缘为进针点,每周1次,5周为1个疗程),根据病程分两组,病程<3个月32例,病程>3个月44例,随访1年观察远期疗效。结果与结论:随访1年发现病程<3个月组的优良率达94%,远期疗效优于病程>3个月组(优良率73%)。治疗期间无明显毒副作用,其中有5例注射后疼痛加重,可能与髌下积液未抽尽和早期穿刺技术不熟练有关,休息后一两天均得到缓解,未发生感染。结果可见玻璃酸钠是治疗髌骨软化症的有效药物,早期治疗及合理的进针点是保证疗效的关键。
基金Supported by the Scientific and Technologic Project of Jiangsu Administration of TCM(No.LZ13243)
文摘OBJECTIVE: To evaluate the clinical effect of traditional Chinese spinal orthopedic manipulation(TCSOM) in treating chondromalacia patellae(CP).METHODS: Sixty cases of CP patients were randomly assigned to a TCSOM group and a Celecoxib group according to the random number table method. All patients in the TCSOM group were treated with a maximum of 10 spinal manipulations and rehabilitation training of quadriceps femoris. The symptoms before and after treatment were assessed with visual analog scale(VAS) and Kujala functional knee scoring system(KFKSS). A symptom improvement rate(SIR) was implemented in order to evaluate the effects of the treatments.RESULTS: The symptoms of 16 patients in the TC-SOM group quickly resolved after the first spinal manipulation and 8 cases were significantly improved. The VAS scores in the TCSOM group after 4weeks of treatment were significantly lower than those in the Celecoxib group. The KFKSS scores in the TCSOM group after 4 weeks of treatment were significantly higher than those in the Celecoxib group. Side effects of the treatment were not reported. Symptom improvement rate based on the VAS in the TCSOM group indicated more significant improvements than the Celecoxib group.CONCLUSION: TCSOM has greater efficacy than Celecoxib capsules for relief of the symptoms of CP.
