The past two decades revealed a plethora of Ca^2＋-responsive proteins and downstream targets in plants, of which several are unique to plants. More recent high-throughput ＇omics＂ approaches and bioinformatics are e...The past two decades revealed a plethora of Ca^2＋-responsive proteins and downstream targets in plants, of which several are unique to plants. More recent high-throughput ＇omics＂ approaches and bioinformatics are exposing Ca^2＋-responsive cis-elements and the corresponding Ca^2＋-responsive genes. Here, we review the current knowledge on Ca^2＋-signaling pathways that regulate gene expression in plants, and we link these to mechanisms by which plants respond to biotic and abiotic stresses.展开更多
Exercise-induced rhabdomyolysis(exRML), a pathophysiological condition of skeletal muscle cell damage that may cause acute renal failure and in some cases death. Increased Ca^(2+) level in cells along with functional ...Exercise-induced rhabdomyolysis(exRML), a pathophysiological condition of skeletal muscle cell damage that may cause acute renal failure and in some cases death. Increased Ca^(2+) level in cells along with functional degradation of cell signaling system and cell matrix have been suggested as the major pathological mechanisms associated with exRML. The onset of exRML may be exhibited in athletes as well as in general population. Previous studies have reported that possible causes of exRML were associated with excessive eccentric contractions in high temperature, abnormal electrolytes balance, and nutritional deficiencies possible genetic defects. However, the underlying mechanisms of exRML have not been clearly established among health professionals or sports medicine personnel. Therefore, we reviewed the possible mechanisms and correlated prevention of exRML, while providing useful and practical information for the athlete and general exercising population.展开更多
文摘The past two decades revealed a plethora of Ca^2＋-responsive proteins and downstream targets in plants, of which several are unique to plants. More recent high-throughput ＇omics＂ approaches and bioinformatics are exposing Ca^2＋-responsive cis-elements and the corresponding Ca^2＋-responsive genes. Here, we review the current knowledge on Ca^2＋-signaling pathways that regulate gene expression in plants, and we link these to mechanisms by which plants respond to biotic and abiotic stresses.
文摘Exercise-induced rhabdomyolysis(exRML), a pathophysiological condition of skeletal muscle cell damage that may cause acute renal failure and in some cases death. Increased Ca^(2+) level in cells along with functional degradation of cell signaling system and cell matrix have been suggested as the major pathological mechanisms associated with exRML. The onset of exRML may be exhibited in athletes as well as in general population. Previous studies have reported that possible causes of exRML were associated with excessive eccentric contractions in high temperature, abnormal electrolytes balance, and nutritional deficiencies possible genetic defects. However, the underlying mechanisms of exRML have not been clearly established among health professionals or sports medicine personnel. Therefore, we reviewed the possible mechanisms and correlated prevention of exRML, while providing useful and practical information for the athlete and general exercising population.
