Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired.Electrospun nanofibrous materials show great application po...Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired.Electrospun nanofibrous materials show great application potentials for wound healing owing to relatively large surface area,better mimicry of native extracellular matrix,adjustable waterproofness and breathability,and programmable drug delivery process.In this review article,we begin with a discussion of wound healing process and current commercial wound dressing materials.Then,we emphasize on electrospun nanofibrous materials for wound dressing,covering the efforts for controlling fiber alignment and morphology,constructing 3D scaffolds,developing waterproof-breathable membrane,governing drug delivery performance,and regulating stem cell behavior.Finally,we finish with challenges and future prospects of electrospun nanofibrous materials for wound dressings.展开更多
Piezoelectric nanogenerators(PENGs)are promising for harvesting renewable and abundant mechanical energy with high efficiency.Up to now,published research studies have mainly focused on increasing the sensitivity and ...Piezoelectric nanogenerators(PENGs)are promising for harvesting renewable and abundant mechanical energy with high efficiency.Up to now,published research studies have mainly focused on increasing the sensitivity and output of PENGs.The technical challenges in relation to practicability,comfort,and antibacterial performance,which are critically important for wearable applications,have not been well addressed.To overcome the limitations,we developed an all-nanofiber PENG(ANF-PENG)with a sandwich structure,in which the middle poly(vinylidene fluoride-co-hexafluoropropylene(P(VDF-HFP))/ZnO electrospun nanofibers serve as the piezoelectric layer,and the above and below electrostatic direct-writing P(VDF-HFP)/ZnO nanofiber membranes with a 110 nm Ag layer on one side that was plated by vacuum coating technique serve as the electrode layer.As the ANF-PENG only has 91μm thick and does not need further encapsulating,it has a high air permeability of 24.97 mm/s.ZnO nanoparticles in ANF-PENG not only improve the piezoelectric output,but also have antibacterial function(over 98%).The multifunctional ANF-PENG demonstrates good sensitivity to human motion and can harvest mechanical energy,indicating great potential applications in flexible self-powered electronic wearables and body health monitoring.展开更多
开发耐用且可靠的生物电极,用以采集高质量的生物电信号,已成为人体生理状态监测和人机交互领域的关键技术.然而,现有的生物电极多基于传统弹性基底,这导致了机械性能不匹配和低渗透性等问题,并且缺乏与生物皮肤类似的多方面属性和必要...开发耐用且可靠的生物电极,用以采集高质量的生物电信号,已成为人体生理状态监测和人机交互领域的关键技术.然而,现有的生物电极多基于传统弹性基底,这导致了机械性能不匹配和低渗透性等问题,并且缺乏与生物皮肤类似的多方面属性和必要的协同特性.本研究中,我们报道了一种新型的基于自支撑导电全聚合物薄膜的超薄表皮生物电极(ASU-EBE).该电极将超一致性、优异的拉伸性和透气性集成于一体,展现了约475 S cm^(-1)的高导电性,约48%的出色拉伸性,与生物组织界面的超一致性以及优异的透气性.该电极的电子和机械性能得到提升,这归功于在PEDOT:PSS中引入水溶性聚氧化乙烯,以调节分子间π-π堆积距离,并促进纳米纤维结构的形成.因此,ASU-EBE在与皮肤接触时的阻抗远低于标准凝胶电极,使其成为复杂日常环境下长期医疗监测的理想选择.展开更多
The successful implementation of bioelectronic devices attached to living organism hinges on a number of material and device characteristics,including not only electrical and mechanical performances to gather physiolo...The successful implementation of bioelectronic devices attached to living organism hinges on a number of material and device characteristics,including not only electrical and mechanical performances to gather physiological signals from living organism thus enabling status monitoring,but also permeability or breathability for gas/nutrient exchange between living organisms and surroundings to ensure minimum perturbation of the intrinsic biological function.However,most bioelectronic devices built on planar polymeric substrates,such as polydimethylsiloxane(PDMS),polyurethane(PU),and polyimide(PI),lack efficient gas permeability,which may hinder the emission of volatile compounds from the surface of living organism,affecting the natural metabolism and reducing the comfort of wearing.Thus,achieving permeability or breathability in bioelectronic devices is a significant challenge.Currently,the devices made of gas-permeable materials with porous structures,that combine electronic components with daily garments,such as fibric and textile,offer exciting opportunities for breathable electronics.In this review,several types of gas-permeable materials with their synthesis and processing routes are outlines.Then,two methods for measuring water vapor transmission rate of materials are discussed in depth.Finally,recent progress in the use of gaspermeable materials for the applications of plant-and skin-attached electronics is summarized systematically.展开更多
基金This work was supported by the National Natural Science Foundation of China(81771338)Natural Science Foundation of Shanghai(19ZR1470500)+1 种基金the Science and Technology Commission of Shanghai Municipality(18511109500)the Fundamental Research Funds for the Central Universities(223201900081).
文摘Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired.Electrospun nanofibrous materials show great application potentials for wound healing owing to relatively large surface area,better mimicry of native extracellular matrix,adjustable waterproofness and breathability,and programmable drug delivery process.In this review article,we begin with a discussion of wound healing process and current commercial wound dressing materials.Then,we emphasize on electrospun nanofibrous materials for wound dressing,covering the efforts for controlling fiber alignment and morphology,constructing 3D scaffolds,developing waterproof-breathable membrane,governing drug delivery performance,and regulating stem cell behavior.Finally,we finish with challenges and future prospects of electrospun nanofibrous materials for wound dressings.
基金The authors acknowledge the financial support from the National Natural Science Foundation of China(No.52073224)Textile Vision Basic Research Program of China(No.J202110)+3 种基金Advanced manufacturing technology project of Xi’an Science and Technology Bureau,China(21XJZZ0019)Scientific Research Project of Shaanxi Provincial Education Department,China(No.22JC035)Key Research and Development Program of Xianyang Science and Technology Bureau,China(No.2021ZDYF-GY-0035)Research Fund for the Doctoral Program of Xi’an Polytechnic University(No.BS202006).
文摘Piezoelectric nanogenerators(PENGs)are promising for harvesting renewable and abundant mechanical energy with high efficiency.Up to now,published research studies have mainly focused on increasing the sensitivity and output of PENGs.The technical challenges in relation to practicability,comfort,and antibacterial performance,which are critically important for wearable applications,have not been well addressed.To overcome the limitations,we developed an all-nanofiber PENG(ANF-PENG)with a sandwich structure,in which the middle poly(vinylidene fluoride-co-hexafluoropropylene(P(VDF-HFP))/ZnO electrospun nanofibers serve as the piezoelectric layer,and the above and below electrostatic direct-writing P(VDF-HFP)/ZnO nanofiber membranes with a 110 nm Ag layer on one side that was plated by vacuum coating technique serve as the electrode layer.As the ANF-PENG only has 91μm thick and does not need further encapsulating,it has a high air permeability of 24.97 mm/s.ZnO nanoparticles in ANF-PENG not only improve the piezoelectric output,but also have antibacterial function(over 98%).The multifunctional ANF-PENG demonstrates good sensitivity to human motion and can harvest mechanical energy,indicating great potential applications in flexible self-powered electronic wearables and body health monitoring.
基金supported by the National Key Research and Development Program of China(2023YFB3608904)the National Natural Science Foundation of China(21835003 and 61704077)+7 种基金the Natural Science Foundation of Jiangsu Province(BE2019120 and BK20191374)the Foundation of Key Laboratory of Flexible Electronics of Zhejiang Province(2023FE002)the Natural Science Foundation of Jiangsu Higher Education Institutions of China(18KJB150025)the Program for Jiangsu SpeciallyAppointed Professor(RK030STP15001)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX21_0778,SJCX21_0298)the NUPT Scientific Foundation(NY219021 and NY219109)the Leading Talent of Technological Innovation of National Ten-Thousands Talents Program of Chinathe Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)。
文摘开发耐用且可靠的生物电极,用以采集高质量的生物电信号,已成为人体生理状态监测和人机交互领域的关键技术.然而,现有的生物电极多基于传统弹性基底,这导致了机械性能不匹配和低渗透性等问题,并且缺乏与生物皮肤类似的多方面属性和必要的协同特性.本研究中,我们报道了一种新型的基于自支撑导电全聚合物薄膜的超薄表皮生物电极(ASU-EBE).该电极将超一致性、优异的拉伸性和透气性集成于一体,展现了约475 S cm^(-1)的高导电性,约48%的出色拉伸性,与生物组织界面的超一致性以及优异的透气性.该电极的电子和机械性能得到提升,这归功于在PEDOT:PSS中引入水溶性聚氧化乙烯,以调节分子间π-π堆积距离,并促进纳米纤维结构的形成.因此,ASU-EBE在与皮肤接触时的阻抗远低于标准凝胶电极,使其成为复杂日常环境下长期医疗监测的理想选择.
基金the financial support from the China Postdoctoral Science Foundation(No.2022M710606(Z.C.Y.))the National Natural Science Foundation of China(Nos.61825102 and U21A20460(Y.L.))+3 种基金the Fundamental Research Funds for the Central Universities of UESTC(No.ZYGX2021YGLH002(Y.L.))the Shenzhen Science and technology planning project(No.JSGG20201102152403008(T.H.))the Project of Innovation and Strong School(No.PT2020C002(X.Z.W.))the Science and Technology Project of Shenzhen City(No.JSGG20210802154213040(X.Z.W.)).
文摘The successful implementation of bioelectronic devices attached to living organism hinges on a number of material and device characteristics,including not only electrical and mechanical performances to gather physiological signals from living organism thus enabling status monitoring,but also permeability or breathability for gas/nutrient exchange between living organisms and surroundings to ensure minimum perturbation of the intrinsic biological function.However,most bioelectronic devices built on planar polymeric substrates,such as polydimethylsiloxane(PDMS),polyurethane(PU),and polyimide(PI),lack efficient gas permeability,which may hinder the emission of volatile compounds from the surface of living organism,affecting the natural metabolism and reducing the comfort of wearing.Thus,achieving permeability or breathability in bioelectronic devices is a significant challenge.Currently,the devices made of gas-permeable materials with porous structures,that combine electronic components with daily garments,such as fibric and textile,offer exciting opportunities for breathable electronics.In this review,several types of gas-permeable materials with their synthesis and processing routes are outlines.Then,two methods for measuring water vapor transmission rate of materials are discussed in depth.Finally,recent progress in the use of gaspermeable materials for the applications of plant-and skin-attached electronics is summarized systematically.
