Brain-controlled technology is the key technology in biological control,and the corresponding relationship between animal brain nuclei and motor behavior is the core.The purpose of this study was to explore the motor ...Brain-controlled technology is the key technology in biological control,and the corresponding relationship between animal brain nuclei and motor behavior is the core.The purpose of this study was to explore the motor nuclei of the medulla oblongata in carp.The carps were subjected to electrical stimulation and chemical stimulation experiments,respectively,in the water-free state,and the effective chemical stimulation sites were injected with the pontamine sky blue solution.The brain tissue sections were obtained by paraffin tissue section technology and the neutral red staining method.By comparing the positions of the brain nuclei shown in earlier studies,the motor nerve nuclei in the medulla oblongata were identified.The brain electrode was implanted into the motor nucleus of the medulla oblongata,and the underwater control experiment and behavioral tests were carried out with different electrical stimulation parameters.The results showed that the abducens nucleus(NVI)was the motor nucleus that controls the ipsilateral steering,and the facial nucleus(NVII)was the motor nucleus that controls the forward movement.By adjusting the stimulation voltage and the stimulation pulse number,the carp can be stably controlled to achieve a left–right steering motion of 30°–180°and a forward motion of more than 80 cm/s.This study indicated that the quantitative control of the steering and forward behavior of the carp can be achieved by electrical stimulation of the NVI and NVII,which provided a certain experimental basis for the accurate control of the carp robot.展开更多
目的研究手法按摩+低频电刺激+生物反馈在性交痛中的效果。方法选择2021年6月—2022年9月晋江市妇幼保健院收治的79例性交痛患者,以随机数字表法分为两组,研究组40例接受手法按摩+低频电刺激+生物反馈治疗,对照组39例实施低频电刺激+生...目的研究手法按摩+低频电刺激+生物反馈在性交痛中的效果。方法选择2021年6月—2022年9月晋江市妇幼保健院收治的79例性交痛患者,以随机数字表法分为两组,研究组40例接受手法按摩+低频电刺激+生物反馈治疗,对照组39例实施低频电刺激+生物反馈,治疗4周后评价总有效率,比较两组干预前后的性功能障碍评分、盆底肌力、尿流动力学指标、视觉模拟评分(visual analogue scale,VAS)、生活质量评分(quality of life,QOL),对比两组治疗结果。结果研究组总有效率为90.00%,高于对照组的71.79%(P<0.05)。两组干预前的性功能障碍评分差异无统计学意义(P>0.05);干预后研究组性生活质量、性欲望、总分均高出对照组(P<0.05)。两组干预前的盆底肌力差异无统计学意义(P>0.05);干预后研究组盆底肌力高于对照组(P<0.05)。两组干预前的VAS、QOL评分差异无统计学意义(P>0.05);干预后研究组VAS评分低于对照组,但QOL评分高于对照组(P<0.05)。两组干预前的尿流动力学指标差异无统计学意义(P>0.05);干预后研究组最大尿道压、腹压漏尿点压力、最大尿流率、最大尿道闭合压评分高于对照组(P<0.05)。结论手法按摩+低频电刺激+生物反馈的效果更为理想,能够缓解性功能障碍,改善盆底肌力及尿流动力学,快速降低疼痛,提高生活质量,值得推广。展开更多
目的分析宫腔镜宫腔粘连分离术(TCRA)治疗宫腔粘连后,以常规药物治疗联合仿生物电刺激技术预防宫腔再次粘连的临床价值。方法选取2018年1月~2019年6月在我院接受TCRA治疗的56例宫腔粘连确诊患者作为研究对象,按照随机数字表法,将其分为...目的分析宫腔镜宫腔粘连分离术(TCRA)治疗宫腔粘连后,以常规药物治疗联合仿生物电刺激技术预防宫腔再次粘连的临床价值。方法选取2018年1月~2019年6月在我院接受TCRA治疗的56例宫腔粘连确诊患者作为研究对象,按照随机数字表法,将其分为对照组(28例)和治疗组(28例)。对照组患者采用TCRA+宫腔内放置透明质酸钠凝胶2 ml及注水4.5~5.0 ml Floy导管+大剂量雌激素孕激素人工周期治疗。治疗组在上述治疗基础上联合仿生物电刺激进行治疗。比较两组患者的宫腔再次粘连事件发生情况、手术治疗总有效率、治疗前后子宫内膜厚度、妊娠结局和月经情况。结果治疗组患者的宫腔粘连复发率低于对照组,差异有统计学意义(P<0.05);治疗组患者的妊娠率高于对照组,差异有统计学意义(P<0.05);治疗组患者的手术总有效率高于对照组,差异有统计学意义(P<0.05);两组患者治疗后的月经量多于治疗前,月经周期短于治疗前,行经时间长于治疗前,差异有统计学意义(P<0.05);治疗后,治疗组患者的月经量多于对照组,月经周期、行经时间长于对照组,差异有统计学意义(P<0.05);两组患者治疗后的子宫内膜厚度均高于治疗前,差异有统计学意义(P<0.05);治疗后,治疗组患者的子宫内膜厚度高于对照组,差异有统计学意义(P<0.05)。结论宫腔粘连患者在TCRA术后采用常规药物联合仿生物电刺激技术进行治疗,可以预防宫腔再次粘连事件的发生,大幅度改善子宫内膜厚度,缩短术后治疗时间,提高妊娠率,使治疗的总有效率得到显著提升。展开更多
基金supported by the Project of National Natural Science Foundation of China(project number:61573305)Project of Natural Science Foundation of Hebei Province of China(project number:F2022203038,F2019203511)National High-Tech Research and Development Plan of China(863 Plan)Project(2013AA****)Fund.
文摘Brain-controlled technology is the key technology in biological control,and the corresponding relationship between animal brain nuclei and motor behavior is the core.The purpose of this study was to explore the motor nuclei of the medulla oblongata in carp.The carps were subjected to electrical stimulation and chemical stimulation experiments,respectively,in the water-free state,and the effective chemical stimulation sites were injected with the pontamine sky blue solution.The brain tissue sections were obtained by paraffin tissue section technology and the neutral red staining method.By comparing the positions of the brain nuclei shown in earlier studies,the motor nerve nuclei in the medulla oblongata were identified.The brain electrode was implanted into the motor nucleus of the medulla oblongata,and the underwater control experiment and behavioral tests were carried out with different electrical stimulation parameters.The results showed that the abducens nucleus(NVI)was the motor nucleus that controls the ipsilateral steering,and the facial nucleus(NVII)was the motor nucleus that controls the forward movement.By adjusting the stimulation voltage and the stimulation pulse number,the carp can be stably controlled to achieve a left–right steering motion of 30°–180°and a forward motion of more than 80 cm/s.This study indicated that the quantitative control of the steering and forward behavior of the carp can be achieved by electrical stimulation of the NVI and NVII,which provided a certain experimental basis for the accurate control of the carp robot.
文摘目的研究手法按摩+低频电刺激+生物反馈在性交痛中的效果。方法选择2021年6月—2022年9月晋江市妇幼保健院收治的79例性交痛患者,以随机数字表法分为两组,研究组40例接受手法按摩+低频电刺激+生物反馈治疗,对照组39例实施低频电刺激+生物反馈,治疗4周后评价总有效率,比较两组干预前后的性功能障碍评分、盆底肌力、尿流动力学指标、视觉模拟评分(visual analogue scale,VAS)、生活质量评分(quality of life,QOL),对比两组治疗结果。结果研究组总有效率为90.00%,高于对照组的71.79%(P<0.05)。两组干预前的性功能障碍评分差异无统计学意义(P>0.05);干预后研究组性生活质量、性欲望、总分均高出对照组(P<0.05)。两组干预前的盆底肌力差异无统计学意义(P>0.05);干预后研究组盆底肌力高于对照组(P<0.05)。两组干预前的VAS、QOL评分差异无统计学意义(P>0.05);干预后研究组VAS评分低于对照组,但QOL评分高于对照组(P<0.05)。两组干预前的尿流动力学指标差异无统计学意义(P>0.05);干预后研究组最大尿道压、腹压漏尿点压力、最大尿流率、最大尿道闭合压评分高于对照组(P<0.05)。结论手法按摩+低频电刺激+生物反馈的效果更为理想,能够缓解性功能障碍,改善盆底肌力及尿流动力学,快速降低疼痛,提高生活质量,值得推广。
文摘目的分析宫腔镜宫腔粘连分离术(TCRA)治疗宫腔粘连后,以常规药物治疗联合仿生物电刺激技术预防宫腔再次粘连的临床价值。方法选取2018年1月~2019年6月在我院接受TCRA治疗的56例宫腔粘连确诊患者作为研究对象,按照随机数字表法,将其分为对照组(28例)和治疗组(28例)。对照组患者采用TCRA+宫腔内放置透明质酸钠凝胶2 ml及注水4.5~5.0 ml Floy导管+大剂量雌激素孕激素人工周期治疗。治疗组在上述治疗基础上联合仿生物电刺激进行治疗。比较两组患者的宫腔再次粘连事件发生情况、手术治疗总有效率、治疗前后子宫内膜厚度、妊娠结局和月经情况。结果治疗组患者的宫腔粘连复发率低于对照组,差异有统计学意义(P<0.05);治疗组患者的妊娠率高于对照组,差异有统计学意义(P<0.05);治疗组患者的手术总有效率高于对照组,差异有统计学意义(P<0.05);两组患者治疗后的月经量多于治疗前,月经周期短于治疗前,行经时间长于治疗前,差异有统计学意义(P<0.05);治疗后,治疗组患者的月经量多于对照组,月经周期、行经时间长于对照组,差异有统计学意义(P<0.05);两组患者治疗后的子宫内膜厚度均高于治疗前,差异有统计学意义(P<0.05);治疗后,治疗组患者的子宫内膜厚度高于对照组,差异有统计学意义(P<0.05)。结论宫腔粘连患者在TCRA术后采用常规药物联合仿生物电刺激技术进行治疗,可以预防宫腔再次粘连事件的发生,大幅度改善子宫内膜厚度,缩短术后治疗时间,提高妊娠率,使治疗的总有效率得到显著提升。
