中国医师协会外科医师分会肥胖和糖尿病外科医师委员会(Chinese Society for Metabolic & Bariatric Surgery,CSMBS)于2014年组织国内减重代谢外科及内分泌科专家共同制定了我国首个减重代谢外科指南——《中国肥胖和2型糖尿病外科...中国医师协会外科医师分会肥胖和糖尿病外科医师委员会(Chinese Society for Metabolic & Bariatric Surgery,CSMBS)于2014年组织国内减重代谢外科及内分泌科专家共同制定了我国首个减重代谢外科指南——《中国肥胖和2型糖尿病外科治疗指南(2014)》[1]。展开更多
据中华医学会糖尿病学分会2008年中国糖尿病和代谢疾病研究（China national diabetes and metabolic disorders study）报告,我国20岁以上人群糖尿病（diabetes mellitus,DM）总体患病率为9.7%,其中男性10.6%,女性8.8%。由此推算我国D...据中华医学会糖尿病学分会2008年中国糖尿病和代谢疾病研究（China national diabetes and metabolic disorders study）报告,我国20岁以上人群糖尿病（diabetes mellitus,DM）总体患病率为9.7%,其中男性10.6%,女性8.8%。由此推算我国DM患病总人数达9240万,位居世界第一。DM前期的患病率高达15.5%,估算人数约为1.5亿。展开更多
Nonalcoholic fatty liver disease (NAFLD) represents a rapidly growing cause of chronic liver disease in the United States and is associated with significant morbidity and mortality,including progression to liver cirrh...Nonalcoholic fatty liver disease (NAFLD) represents a rapidly growing cause of chronic liver disease in the United States and is associated with significant morbidity and mortality,including progression to liver cirrhosis and hepatocellular carcinoma.NAFLD comprises a spectrum of liver conditions,ranging from simple steatosis to steatosis with inflammation (steatohepatitis) and progressive fibrosis.Weight loss represents a first line therapeutic modality for the management of NAFLD.Herein,we review the evidence base for medical,surgical,and endoscopic approaches to weight loss and their potential impact on the natural history of NAFLD.展开更多
AIM: To evaluate the prognosis of type Ⅱ diabetes mellitus (T2DM) after gastrectomy and related factors in gastric cancer patients. METHODS: 403 gastric cancer patients with T2DM were studied, who underwent gastrecto...AIM: To evaluate the prognosis of type Ⅱ diabetes mellitus (T2DM) after gastrectomy and related factors in gastric cancer patients. METHODS: 403 gastric cancer patients with T2DM were studied, who underwent gastrectomy between May 2003 and September 2009. A review of medica records and telephone interviews was performed in this cross-sectional study. The factors included in the statistical analysis were as follows: gender, age, type of surgery, preoperative body mass index (BMI), current BMI, BMI reduction ratio, preoperative insulin or oral diabetic medicine requirement, follow-up duration, and current state of diabetes. Assessment of diabetes status after surgery was classified into four categories according to the change in hypoglycemic agents after surgery and present status of T2DM: resolution, improvement, same, and worse.(± 20.6 mo), preoperative BMI was 24.7 kg/m2 (± 3.0 kg/m2), and BMI reduction ratio was 9.8% (± 8.6%). After surgery, T2DM was cured in 58 patients (15.1%) and was improved in 117 patients (30.4%). According to the type of surgery, the BMI reduction ratio was signif icantly higher in the total gastrectomy and Roux-en-Y reconstruction group [14.2% ± 9.2% vs 9.2% ± 7.7% (Billroth Ⅱ group), P < 0.001] and signif icantly lower in the subtotal gastrectomy and Billroth Ⅰ reconstruction group [7.6% ± 8.0%, 9.2% ± 7.7% (Billroth Ⅱ group), P < 0.001]. The BMI reduction ratio, follow-up duration after surgery, type of surgery, extent of gastrectomy, and performance of duodenal bypass were signif icantly correlated to the course of T2DM (P < 0.05). The BMI reduction ratio was the most influential factor on T2DM status. In a subgroup analysis of patients with a BMI reduction ratio of 10% or less (n = 206), T2DM was cured in 15 (7.6%) patients and was improved in 57 (28.8%) patients after surgery, and only the duration of surgery was signif icantly correlated to T2DM status (P = 0.022).展开更多
文摘中国医师协会外科医师分会肥胖和糖尿病外科医师委员会(Chinese Society for Metabolic & Bariatric Surgery,CSMBS)于2014年组织国内减重代谢外科及内分泌科专家共同制定了我国首个减重代谢外科指南——《中国肥胖和2型糖尿病外科治疗指南(2014)》[1]。
文摘据中华医学会糖尿病学分会2008年中国糖尿病和代谢疾病研究（China national diabetes and metabolic disorders study）报告,我国20岁以上人群糖尿病（diabetes mellitus,DM）总体患病率为9.7%,其中男性10.6%,女性8.8%。由此推算我国DM患病总人数达9240万,位居世界第一。DM前期的患病率高达15.5%,估算人数约为1.5亿。
文摘Nonalcoholic fatty liver disease (NAFLD) represents a rapidly growing cause of chronic liver disease in the United States and is associated with significant morbidity and mortality,including progression to liver cirrhosis and hepatocellular carcinoma.NAFLD comprises a spectrum of liver conditions,ranging from simple steatosis to steatosis with inflammation (steatohepatitis) and progressive fibrosis.Weight loss represents a first line therapeutic modality for the management of NAFLD.Herein,we review the evidence base for medical,surgical,and endoscopic approaches to weight loss and their potential impact on the natural history of NAFLD.
文摘AIM: To evaluate the prognosis of type Ⅱ diabetes mellitus (T2DM) after gastrectomy and related factors in gastric cancer patients. METHODS: 403 gastric cancer patients with T2DM were studied, who underwent gastrectomy between May 2003 and September 2009. A review of medica records and telephone interviews was performed in this cross-sectional study. The factors included in the statistical analysis were as follows: gender, age, type of surgery, preoperative body mass index (BMI), current BMI, BMI reduction ratio, preoperative insulin or oral diabetic medicine requirement, follow-up duration, and current state of diabetes. Assessment of diabetes status after surgery was classified into four categories according to the change in hypoglycemic agents after surgery and present status of T2DM: resolution, improvement, same, and worse.(± 20.6 mo), preoperative BMI was 24.7 kg/m2 (± 3.0 kg/m2), and BMI reduction ratio was 9.8% (± 8.6%). After surgery, T2DM was cured in 58 patients (15.1%) and was improved in 117 patients (30.4%). According to the type of surgery, the BMI reduction ratio was signif icantly higher in the total gastrectomy and Roux-en-Y reconstruction group [14.2% ± 9.2% vs 9.2% ± 7.7% (Billroth Ⅱ group), P < 0.001] and signif icantly lower in the subtotal gastrectomy and Billroth Ⅰ reconstruction group [7.6% ± 8.0%, 9.2% ± 7.7% (Billroth Ⅱ group), P < 0.001]. The BMI reduction ratio, follow-up duration after surgery, type of surgery, extent of gastrectomy, and performance of duodenal bypass were signif icantly correlated to the course of T2DM (P < 0.05). The BMI reduction ratio was the most influential factor on T2DM status. In a subgroup analysis of patients with a BMI reduction ratio of 10% or less (n = 206), T2DM was cured in 15 (7.6%) patients and was improved in 57 (28.8%) patients after surgery, and only the duration of surgery was signif icantly correlated to T2DM status (P = 0.022).
