目的探讨背阔肌肌皮瓣联合自体脂肪组织即刻乳房重建在乳腺癌术后的应用价值。方法回顾性分析2014年1月至2019年1月于深圳市中医院行乳腺癌改良根治术治疗的86例乳腺癌患者的临床资料,根据乳房重建方式的不同将其分为假体组(40例)和自...目的探讨背阔肌肌皮瓣联合自体脂肪组织即刻乳房重建在乳腺癌术后的应用价值。方法回顾性分析2014年1月至2019年1月于深圳市中医院行乳腺癌改良根治术治疗的86例乳腺癌患者的临床资料,根据乳房重建方式的不同将其分为假体组(40例)和自体脂肪组(46例)。两组患者均行常规乳腺癌改良根治术,假体组患者在术后行背阔肌肌皮瓣联合假体置入即刻乳房重建,自体脂肪组患者在术后行背阔肌肌皮瓣联合自体脂肪组织置入即刻乳房重建。比较两组患者术后临床情况、癌症自我管理效能感量表(strategies used by people to promote health,SUPPH)、生活质量核心量表(quality of life questionnaire-core 30,QLQ-30)、生活质量满意度、美观效果和并发症发生情况。结果两组患者术后引流时间、住院天数、开始辅助治疗时间比较差异均无统计学意义(均P>0.05)。两组患者术后SUPPH、QLQ-30评分均显著高于本组术前(均P<0.05),自体脂肪组患者术后SUPPH、QLQ-30评分均显著高于假体组(均P<0.05)。自体脂肪组患者术后焦虑占比和术后总并发症发生率均显著低于假体组(均P<0.05),对体型、社交满意的占比和美学效果优良率均显著高于假体组(均P<0.05)。结论乳腺癌改良根治术后行背阔肌肌皮瓣联合自体脂肪组织即刻乳房重建安全性较高,美观效果较好,可显著提高患者生活质量。展开更多
Objective: To evaluate the efficacy based on clinical symptom and on magnetic resonance image of platelet-rich plasma therapy in combination with mesenchymal stem cells from autologous adipose tissue for knee osteoart...Objective: To evaluate the efficacy based on clinical symptom and on magnetic resonance image of platelet-rich plasma therapy in combination with mesenchymal stem cells from autologous adipose tissue for knee osteoarthritis treatment. Patients and Method: 30 patients including 26 females and 4 males;correspondingly, 60 knee joints were diagnosed with osteoarthritis with stages II - III of Kellgren and Lawrence, their mean age was 58.63 ± 11.11. All were injected with autologous platelet-rich plasma that was extracted by PRP set, APC 30 PRP PRCEDURE PRAK and autologously extracted mesenchymal stem cells from abdominal adipose tissue using the ADI-25-01 ADIPOSEPRCEDURE PRAK of USA. Results: After 12 months: the pain level according to VAS score at the right knee joint was decreased from 6.0 ± 1.28 before treatment to 1.9 ± 0.3;VAS score at the left knee joint was decreased from 6.43 ± 1.19 to 2.25 ± 0.43. Total Lequene score at right knee joint was decreased from 16.04 ± 1.57 before treatment to 4.31 ± 1.04, at left knee joint was decreased from 17.52 ± 1.74 before treatment to 5.15 ± 1.48. Total WOMAC score at right knee joint was decreased from 55.93 ± 5.56 to 10.37 ± 1.56;at left knee joint was decreased from 53.97 ± 5.57 to 10.07 ± 1.59. There were 86.77% joints with cartilage thickness change and the patellar cartilage thickness was increased from 1.56 ± 0.09 mm before treatment to 1.65 ± 0.09 mm. Conclusion: The treatment of knee osteoarthritis by platelet-rich plasma therapyin combination with mesenchymal stem cells from autologous adipose tissue is effective in reducing pain, improving patient's mobility and walking function, reforming articular cartilage thickness on magnetic resonance image.展开更多
文摘目的探讨背阔肌肌皮瓣联合自体脂肪组织即刻乳房重建在乳腺癌术后的应用价值。方法回顾性分析2014年1月至2019年1月于深圳市中医院行乳腺癌改良根治术治疗的86例乳腺癌患者的临床资料,根据乳房重建方式的不同将其分为假体组(40例)和自体脂肪组(46例)。两组患者均行常规乳腺癌改良根治术,假体组患者在术后行背阔肌肌皮瓣联合假体置入即刻乳房重建,自体脂肪组患者在术后行背阔肌肌皮瓣联合自体脂肪组织置入即刻乳房重建。比较两组患者术后临床情况、癌症自我管理效能感量表(strategies used by people to promote health,SUPPH)、生活质量核心量表(quality of life questionnaire-core 30,QLQ-30)、生活质量满意度、美观效果和并发症发生情况。结果两组患者术后引流时间、住院天数、开始辅助治疗时间比较差异均无统计学意义(均P>0.05)。两组患者术后SUPPH、QLQ-30评分均显著高于本组术前(均P<0.05),自体脂肪组患者术后SUPPH、QLQ-30评分均显著高于假体组(均P<0.05)。自体脂肪组患者术后焦虑占比和术后总并发症发生率均显著低于假体组(均P<0.05),对体型、社交满意的占比和美学效果优良率均显著高于假体组(均P<0.05)。结论乳腺癌改良根治术后行背阔肌肌皮瓣联合自体脂肪组织即刻乳房重建安全性较高,美观效果较好,可显著提高患者生活质量。
文摘Objective: To evaluate the efficacy based on clinical symptom and on magnetic resonance image of platelet-rich plasma therapy in combination with mesenchymal stem cells from autologous adipose tissue for knee osteoarthritis treatment. Patients and Method: 30 patients including 26 females and 4 males;correspondingly, 60 knee joints were diagnosed with osteoarthritis with stages II - III of Kellgren and Lawrence, their mean age was 58.63 ± 11.11. All were injected with autologous platelet-rich plasma that was extracted by PRP set, APC 30 PRP PRCEDURE PRAK and autologously extracted mesenchymal stem cells from abdominal adipose tissue using the ADI-25-01 ADIPOSEPRCEDURE PRAK of USA. Results: After 12 months: the pain level according to VAS score at the right knee joint was decreased from 6.0 ± 1.28 before treatment to 1.9 ± 0.3;VAS score at the left knee joint was decreased from 6.43 ± 1.19 to 2.25 ± 0.43. Total Lequene score at right knee joint was decreased from 16.04 ± 1.57 before treatment to 4.31 ± 1.04, at left knee joint was decreased from 17.52 ± 1.74 before treatment to 5.15 ± 1.48. Total WOMAC score at right knee joint was decreased from 55.93 ± 5.56 to 10.37 ± 1.56;at left knee joint was decreased from 53.97 ± 5.57 to 10.07 ± 1.59. There were 86.77% joints with cartilage thickness change and the patellar cartilage thickness was increased from 1.56 ± 0.09 mm before treatment to 1.65 ± 0.09 mm. Conclusion: The treatment of knee osteoarthritis by platelet-rich plasma therapyin combination with mesenchymal stem cells from autologous adipose tissue is effective in reducing pain, improving patient's mobility and walking function, reforming articular cartilage thickness on magnetic resonance image.
