AIM: To study the cannulation and complication rates of early pre-cut sphincterotomy vs persistent attempts at cannulation by standard approach.METHODS: Systematic search of PubMed, EMBASE, Web of Science, and the Coc...AIM: To study the cannulation and complication rates of early pre-cut sphincterotomy vs persistent attempts at cannulation by standard approach.METHODS: Systematic search of PubMed, EMBASE, Web of Science, and the Cochrane Library for relevant studies published up to February 2013. The main outcome measurements were cannulation rates and postendoscopic retrograde cholangiopancreatography(ERCP) complications. A comprehensive systematic search of the Cochrane library, PubMed, Google scholar, Scopus, National Institutes of Health, meta-register of controlled trials and published proceedings from major Gastroenterology journals and meetings until February 2013 was conducted using keywords. All Prospective randomized controlled trials(RCT) studies whichmet our inclusion criteria were included in the analysis. Prospective non-randomized studies and retrospective studies were excluded from our meta-analysis. The main outcomes of interest were post-ERCP pancreatitis, overall complication rates including cholangitis, ERCPrelated bleeding, perforation and cannulation success rates. RESULTS: Seven RCTs with a total of 1039 patients were included in the meta-analysis based on selection criteria. The overall cannulation rate was 90% in the pre-cut sphincterotomy vs 86.3% in the persistent attempts group(OR = 1.98; 95%CI: 0.70-5.65). The risk of post-ERCP pancreatitis(PEP) was not different between the two groups(3.9% in the pre-cut sphincterotomy vs 6.1% in the persistent attempts group, OR = 0.58, 95%CI: 0.32-1.05). Similarly, there was no statistically significant difference between the groups for overall complication rate including PEP, cholangitis, bleeding, and perforation(6.2% vs 6.9%, OR = 0.85, 95%CI: 0.51-1.41). CONCLUSION: This meta-analysis suggests that precut sphincterotomy and persistent attempts at cannulation are comparable in terms of overall complication rates. Early pre-cut implementation does not increase PEP complications.展开更多
BACKGROUND Previous studies found several factors associated with suicide in schizophrenic patients,such as age,sex,education level,history of suicide attempts,psychotic symptoms,social factors,and substance abuse.How...BACKGROUND Previous studies found several factors associated with suicide in schizophrenic patients,such as age,sex,education level,history of suicide attempts,psychotic symptoms,social factors,and substance abuse.However,there might be some additional factors that were not considered in previous studies but may be correlated with a greater likelihood of suicide attempts,such as medication and treatment.AIM To investigate the prevalence of suicide attempts and identify the risk of suicidality in hospitalized schizophrenia patients.METHODS This is a cross-sectional study of schizophrenic patients admitted to a psychiatric hospital who were 18 years of age or more.The outcomes and possible suicide risk factors in these patients were collated.The current suicide risk was evaluated using the mini-international neuropsychiatric interview module for suicidality and categorized as none(0 points),mild(1-8 points),moderate(9-16 points),or severe(17 or more points).This study used ordinal logistic regression to assess the association of potential risk factors with the current suicide risk in schizophrenic patients.RESULTS Of 228 hospitalized schizophrenia patients,214(93.9%)were included in this study.The majority(79.0%)of patients were males.Females appeared to have a slightly higher suicidality risk than males,with borderline significance.With regard to the current suicide risk assessed with the mini-international neuropsychiatric interview,172(80.4%)schizophrenic patients scored zero,20(9.4%)had a mild risk,8(3.7%)had a moderate risk,and 14(6.5%)had a severe risk.The total prevalence of current suicide risk in these schizophrenic patients was 19.6%.Based on multivariable ordinal logistic regression analysis with backward elimination,it was found that younger age,a current major depressive episode,receiving fluoxetine or lithium carbonate in the previous month,or a relatively higher Charlson comorbidity index score were all significantly and independently associated with a higher level of suicide risk.CONCLUSION The prev展开更多
Writing is one of the required abilities in learning a foreign language and it is the most difficult to master as well. Though nearly all the students have learned English for at least six years, when it comes to writ...Writing is one of the required abilities in learning a foreign language and it is the most difficult to master as well. Though nearly all the students have learned English for at least six years, when it comes to writing, they are incompetent for it and mistakes appear in their writing time and again. This article means to analyze the reasons of mistakes and attempts to offer some possible means to correct them. Thus students’ writing can be improved.展开更多
Research has indicated that child maltreatment is associated with an increased likelihood of mental disorders and suicidal ideation and attempts that continues into adulthood. The purpose of this paper is to provide a...Research has indicated that child maltreatment is associated with an increased likelihood of mental disorders and suicidal ideation and attempts that continues into adulthood. The purpose of this paper is to provide a synopsis of the recent published research from 2006 to 2010 on the association between child maltreatment and Axis I mental disorders and suicidal ideation and attempts. The databases MEDLINE and PsycINFO were searched for relevant and high quality citations up to October 2010. The results indicated that all types of child maltreatment examined are linked to reduced mental health. A general noted trend in the literature is that earlier age of onset of child maltreatment is associated with poorer mental health outcomes. Sex differences do exist with some disorders being more likely among males (e.g., anti-social behaviour) and other more likely among females (e.g., depression, PTSD, substance use disorders) following child maltreatment.展开更多
A case-control study was conducted to investigate associations between organophosphate pesticide（OP）exposure,aggression,impulsivity,and attempted suicide.Questionnaires were used to collect information;impulsivity a...A case-control study was conducted to investigate associations between organophosphate pesticide（OP）exposure,aggression,impulsivity,and attempted suicide.Questionnaires were used to collect information;impulsivity and aggression were measured by the Barratt Impulsivity Scale（BIS）and the Aggression Inventory（AI）.展开更多
Background: The association of eating habits and suicide attempts has been insufficiently studied. Aim: This study aimed to determine the eating habits associated with suicide attempts in a sample of psychiatric outpa...Background: The association of eating habits and suicide attempts has been insufficiently studied. Aim: This study aimed to determine the eating habits associated with suicide attempts in a sample of psychiatric outpatients. Methods: Through a case control study design, 283 psychiatric outpatients attending in two public hospitals in Durango City, Mexico were studied. Of the 283 patients, 156 have had suicide attempts and 127 have not had suicide attempts. Eating habits were obtained from all outpatients and compared in patients with history of suicide attempts and patients without such history. Results: Logistic regression analysis showed differences in eating habits between psychiatric outpatients with and without history of suicide attempts. A history of suicide attempts was positively associated with consumption of pork (OR = 2.35, 95% CI: 1.17 - 4.71;P = 0.01), mutton (OR = 2.38, 95% CI: 1.25 - 4.52;P = 0.008), chorizo (OR = 2.09, 95% CI: 1.04 - 4.19;P = 0.03), unwashed raw vegetables (OR = 3.23, 95% CI: 1.26 - 8.32;P = 0.01), and untreated water (OR = 1.77, 95% CI: 1.03 - 3.02;P = 0.03), and negatively associated with consumption of goat meat (OR = 0.39, 95% CI: 0.17 - 0.90;P = 0.02), and turkey meat (OR = 0.41, 95% CI: 0.23 - 0.73;P = 0.002). Conclusions: This is the first report on the association of eating habits with suicide attempts in psychiatric outpatients. Results suggest that suicide attempts are associated not only with the type of meat consumed but also with poor food hygiene in psychiatric outpatients. Further studies to confirm or challenge such results are needed.展开更多
Background:Cannulation of the common bile duct(CBD)is the initial and sometime challenging step in endoscopic retrograde cholangiopancreatography(ERCP)procedure.Endoscopists often use cannulation attempts and cannulat...Background:Cannulation of the common bile duct(CBD)is the initial and sometime challenging step in endoscopic retrograde cholangiopancreatography(ERCP)procedure.Endoscopists often use cannulation attempts and cannulation time to grade cannulation difficulty,but a standard system has yet to be established.The objective of this study was to compare cannulation times with numbers of cannulation attempts,as measures of cannulation difficulty.Methods:We conducted a prospective study in a tertiary referral center,enrolling 58 patients who were undergoing ERCP for a variety of indications.Cannulation time and the number of cannulation attempts were recorded for each patient.A subset of 14 ERCPs had two observers assessing attempts at cannulation.Cannulation time,number of attempts and inter-observer variability in assessment of attempts were compared and studied.Results:The degree of agreement between two the methods(cannulation times and number of cannulation attempts)was unacceptable.There were considerable discrepancies between attempt tallies from two observers but the mean difference was statistically insignificant.Conclusion:The grade of cannulation difficulty for a given ERCP procedure may differ when different methods are used(total cannulation time vs number of attempts);thus,grading by different methods should not be used interchangeably.Cannulation time is a more objective and more accurate assessment tool for grading cannulation difficulty than the number of attempts to cannulate the papilla.展开更多
The brain is among the most energetically costly organs in vertebrates,and thus trade-offs have been hypothesized to exert constraints on brain size evolution.The energy trade-off hypothesis(ETH) predicts that reducin...The brain is among the most energetically costly organs in vertebrates,and thus trade-offs have been hypothesized to exert constraints on brain size evolution.The energy trade-off hypothesis(ETH) predicts that reducing the energy consumption of reproduction or other costly tissues should compensate for the cost of a large brain.Egg production in birds requires a large proportion of the total energy budget,and a clutch mass in some bird species can outweigh the body mass of the female.To date,this hypothesis has mainly been tested in mammals and ectothermic animals such as anurans and fishes.We collated data on adult brain size,body mass and eggproduction traits such as clutch size,egg mass and annual broods from published studies,and conducted a phylogenetic comparative test of the interplay between egg-production investment and brain size evolution across bird species.After controlling for phylogenetic relationships and body size,we find a negative correlation between brain size and clutch size across 1395 species,which favored ETH.However,when egg mass was integrated in models,positive associations were detected between brain size and mass of eggs(via egg mass,clutch mass and annual total egg mass).Our results suggest that brain size trades off against egg-production only via certain aspects(e.g.,clutch size).By contrast,a positive relationship between brain size and total egg reproduction(e.g.,clutch mass and annual total egg mass) implied increased total energy budget outweighing energy allocation across bird species.Our study shows that there is no general energy trade-off between brain size and eggreproduction investment,and suggests that brain size evolution follows mixed strategies across bird species.展开更多
This study aimed to clarify the difference between the not qualified teams and the qualified teams to 2nd stage in the Pass Appearance Time and passes attempted at all group stage games of World Cup 2014 and compared ...This study aimed to clarify the difference between the not qualified teams and the qualified teams to 2nd stage in the Pass Appearance Time and passes attempted at all group stage games of World Cup 2014 and compared with World cup 2010. Results indicated changes in passing in modem football tactics. Actual playing time is represented as Net Playtime in this study. Pass Appearance Time is calculated by Net Playtime divided by passes Attempted. Pass Appearance Time of each team for the all Group stage games was calculated and compared with World cup 2010. No difference was revealed in the 2014 data between teams that did and did not qualify, though the 2010 data revealed differences. World cup 2010 data suggested that increasing passes attempts and lessening Pass Appearance Time were effective in qualifying for the 2rid stage. World cup 2014 data, however, suggested that diversity of tactics was important.展开更多
文摘AIM: To study the cannulation and complication rates of early pre-cut sphincterotomy vs persistent attempts at cannulation by standard approach.METHODS: Systematic search of PubMed, EMBASE, Web of Science, and the Cochrane Library for relevant studies published up to February 2013. The main outcome measurements were cannulation rates and postendoscopic retrograde cholangiopancreatography(ERCP) complications. A comprehensive systematic search of the Cochrane library, PubMed, Google scholar, Scopus, National Institutes of Health, meta-register of controlled trials and published proceedings from major Gastroenterology journals and meetings until February 2013 was conducted using keywords. All Prospective randomized controlled trials(RCT) studies whichmet our inclusion criteria were included in the analysis. Prospective non-randomized studies and retrospective studies were excluded from our meta-analysis. The main outcomes of interest were post-ERCP pancreatitis, overall complication rates including cholangitis, ERCPrelated bleeding, perforation and cannulation success rates. RESULTS: Seven RCTs with a total of 1039 patients were included in the meta-analysis based on selection criteria. The overall cannulation rate was 90% in the pre-cut sphincterotomy vs 86.3% in the persistent attempts group(OR = 1.98; 95%CI: 0.70-5.65). The risk of post-ERCP pancreatitis(PEP) was not different between the two groups(3.9% in the pre-cut sphincterotomy vs 6.1% in the persistent attempts group, OR = 0.58, 95%CI: 0.32-1.05). Similarly, there was no statistically significant difference between the groups for overall complication rate including PEP, cholangitis, bleeding, and perforation(6.2% vs 6.9%, OR = 0.85, 95%CI: 0.51-1.41). CONCLUSION: This meta-analysis suggests that precut sphincterotomy and persistent attempts at cannulation are comparable in terms of overall complication rates. Early pre-cut implementation does not increase PEP complications.
基金Supported by the Faculty of Medicine,Chiang Mai University,No.046/2557Chiang Mai University,No.04/2562
文摘BACKGROUND Previous studies found several factors associated with suicide in schizophrenic patients,such as age,sex,education level,history of suicide attempts,psychotic symptoms,social factors,and substance abuse.However,there might be some additional factors that were not considered in previous studies but may be correlated with a greater likelihood of suicide attempts,such as medication and treatment.AIM To investigate the prevalence of suicide attempts and identify the risk of suicidality in hospitalized schizophrenia patients.METHODS This is a cross-sectional study of schizophrenic patients admitted to a psychiatric hospital who were 18 years of age or more.The outcomes and possible suicide risk factors in these patients were collated.The current suicide risk was evaluated using the mini-international neuropsychiatric interview module for suicidality and categorized as none(0 points),mild(1-8 points),moderate(9-16 points),or severe(17 or more points).This study used ordinal logistic regression to assess the association of potential risk factors with the current suicide risk in schizophrenic patients.RESULTS Of 228 hospitalized schizophrenia patients,214(93.9%)were included in this study.The majority(79.0%)of patients were males.Females appeared to have a slightly higher suicidality risk than males,with borderline significance.With regard to the current suicide risk assessed with the mini-international neuropsychiatric interview,172(80.4%)schizophrenic patients scored zero,20(9.4%)had a mild risk,8(3.7%)had a moderate risk,and 14(6.5%)had a severe risk.The total prevalence of current suicide risk in these schizophrenic patients was 19.6%.Based on multivariable ordinal logistic regression analysis with backward elimination,it was found that younger age,a current major depressive episode,receiving fluoxetine or lithium carbonate in the previous month,or a relatively higher Charlson comorbidity index score were all significantly and independently associated with a higher level of suicide risk.CONCLUSION The prev
文摘Writing is one of the required abilities in learning a foreign language and it is the most difficult to master as well. Though nearly all the students have learned English for at least six years, when it comes to writing, they are incompetent for it and mistakes appear in their writing time and again. This article means to analyze the reasons of mistakes and attempts to offer some possible means to correct them. Thus students’ writing can be improved.
文摘Research has indicated that child maltreatment is associated with an increased likelihood of mental disorders and suicidal ideation and attempts that continues into adulthood. The purpose of this paper is to provide a synopsis of the recent published research from 2006 to 2010 on the association between child maltreatment and Axis I mental disorders and suicidal ideation and attempts. The databases MEDLINE and PsycINFO were searched for relevant and high quality citations up to October 2010. The results indicated that all types of child maltreatment examined are linked to reduced mental health. A general noted trend in the literature is that earlier age of onset of child maltreatment is associated with poorer mental health outcomes. Sex differences do exist with some disorders being more likely among males (e.g., anti-social behaviour) and other more likely among females (e.g., depression, PTSD, substance use disorders) following child maltreatment.
基金partially supported by the Colorado Injury Control Research Center Grant Number 5R49CE001168 from the Centers for Disease Control and Preventionthe USA-China Agricultural Injury Research Training Project Grant Number 5DW43TW007257 from the National Institutes of Health,Fogarty International Center
文摘A case-control study was conducted to investigate associations between organophosphate pesticide（OP）exposure,aggression,impulsivity,and attempted suicide.Questionnaires were used to collect information;impulsivity and aggression were measured by the Barratt Impulsivity Scale（BIS）and the Aggression Inventory（AI）.
文摘Background: The association of eating habits and suicide attempts has been insufficiently studied. Aim: This study aimed to determine the eating habits associated with suicide attempts in a sample of psychiatric outpatients. Methods: Through a case control study design, 283 psychiatric outpatients attending in two public hospitals in Durango City, Mexico were studied. Of the 283 patients, 156 have had suicide attempts and 127 have not had suicide attempts. Eating habits were obtained from all outpatients and compared in patients with history of suicide attempts and patients without such history. Results: Logistic regression analysis showed differences in eating habits between psychiatric outpatients with and without history of suicide attempts. A history of suicide attempts was positively associated with consumption of pork (OR = 2.35, 95% CI: 1.17 - 4.71;P = 0.01), mutton (OR = 2.38, 95% CI: 1.25 - 4.52;P = 0.008), chorizo (OR = 2.09, 95% CI: 1.04 - 4.19;P = 0.03), unwashed raw vegetables (OR = 3.23, 95% CI: 1.26 - 8.32;P = 0.01), and untreated water (OR = 1.77, 95% CI: 1.03 - 3.02;P = 0.03), and negatively associated with consumption of goat meat (OR = 0.39, 95% CI: 0.17 - 0.90;P = 0.02), and turkey meat (OR = 0.41, 95% CI: 0.23 - 0.73;P = 0.002). Conclusions: This is the first report on the association of eating habits with suicide attempts in psychiatric outpatients. Results suggest that suicide attempts are associated not only with the type of meat consumed but also with poor food hygiene in psychiatric outpatients. Further studies to confirm or challenge such results are needed.
文摘Background:Cannulation of the common bile duct(CBD)is the initial and sometime challenging step in endoscopic retrograde cholangiopancreatography(ERCP)procedure.Endoscopists often use cannulation attempts and cannulation time to grade cannulation difficulty,but a standard system has yet to be established.The objective of this study was to compare cannulation times with numbers of cannulation attempts,as measures of cannulation difficulty.Methods:We conducted a prospective study in a tertiary referral center,enrolling 58 patients who were undergoing ERCP for a variety of indications.Cannulation time and the number of cannulation attempts were recorded for each patient.A subset of 14 ERCPs had two observers assessing attempts at cannulation.Cannulation time,number of attempts and inter-observer variability in assessment of attempts were compared and studied.Results:The degree of agreement between two the methods(cannulation times and number of cannulation attempts)was unacceptable.There were considerable discrepancies between attempt tallies from two observers but the mean difference was statistically insignificant.Conclusion:The grade of cannulation difficulty for a given ERCP procedure may differ when different methods are used(total cannulation time vs number of attempts);thus,grading by different methods should not be used interchangeably.Cannulation time is a more objective and more accurate assessment tool for grading cannulation difficulty than the number of attempts to cannulate the papilla.
基金National Natural Science Foun-dation of China(Grant No.32170481 and Grant No.3221153042).
文摘The brain is among the most energetically costly organs in vertebrates,and thus trade-offs have been hypothesized to exert constraints on brain size evolution.The energy trade-off hypothesis(ETH) predicts that reducing the energy consumption of reproduction or other costly tissues should compensate for the cost of a large brain.Egg production in birds requires a large proportion of the total energy budget,and a clutch mass in some bird species can outweigh the body mass of the female.To date,this hypothesis has mainly been tested in mammals and ectothermic animals such as anurans and fishes.We collated data on adult brain size,body mass and eggproduction traits such as clutch size,egg mass and annual broods from published studies,and conducted a phylogenetic comparative test of the interplay between egg-production investment and brain size evolution across bird species.After controlling for phylogenetic relationships and body size,we find a negative correlation between brain size and clutch size across 1395 species,which favored ETH.However,when egg mass was integrated in models,positive associations were detected between brain size and mass of eggs(via egg mass,clutch mass and annual total egg mass).Our results suggest that brain size trades off against egg-production only via certain aspects(e.g.,clutch size).By contrast,a positive relationship between brain size and total egg reproduction(e.g.,clutch mass and annual total egg mass) implied increased total energy budget outweighing energy allocation across bird species.Our study shows that there is no general energy trade-off between brain size and eggreproduction investment,and suggests that brain size evolution follows mixed strategies across bird species.
文摘This study aimed to clarify the difference between the not qualified teams and the qualified teams to 2nd stage in the Pass Appearance Time and passes attempted at all group stage games of World Cup 2014 and compared with World cup 2010. Results indicated changes in passing in modem football tactics. Actual playing time is represented as Net Playtime in this study. Pass Appearance Time is calculated by Net Playtime divided by passes Attempted. Pass Appearance Time of each team for the all Group stage games was calculated and compared with World cup 2010. No difference was revealed in the 2014 data between teams that did and did not qualify, though the 2010 data revealed differences. World cup 2010 data suggested that increasing passes attempts and lessening Pass Appearance Time were effective in qualifying for the 2rid stage. World cup 2014 data, however, suggested that diversity of tactics was important.
